MichaelH.RoehrlMDPhD MBA

PubMed

• Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures.
  Atsushi Tanaka, Makiko Ogawa, Yihua Zhou, Kei Namba, Ronald C Hendrickson, Matthew M Miele, Zhuoning Li, David S Klimstra, Patrick G Buckley, Jeffrey Gulcher, Julia Y ...> ;Cell Reports. 2024 Feb 27
• Technical report: The clinically useful selection of proteins protocol: An approach to identify clinically useful proteins for validation.
  Ella E K Swaney, Stephen Hearps, Paul Monagle, Michael H A Roehrl, Vera Ignjatovic> ;Journal of Proteomics. 2024 Mar 30
• Reliability and Variability of Ki-67 Digital Image Analysis Methods for Clinical Diagnostics in Breast Cancer.
  Dawe, M., Shi, W., Liu, T., Lajkosz, K., Shibahara, Y., Gopal, N., Geread, R., Mirjahanmardi, S., Wei, C., Butt, S., Abdalla, M., Manolescu, S., Liang, S., Chadwick, D...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2024 Jan 25
• 1 citations
  The 2023 Report on the Proteome from the HUPO Human Proteome Project.
  Gilbert S Omenn, Lydie Lane, Christopher M Overall, Cecilia Lindskog, Charles Pineau, Nicolle H Packer, Ileana M Cristea, Susan T Weintraub, Sandra Orchard, Michael H ...> ;Journal of Proteome Research. 2024 Feb 2
• Dramatic, durable response to therapy in gBRCA2-mutated pancreas neuroendocrine carcinoma: opportunity and challenge.
  Fergus Keane, Raazi Bajwa, Pier Selenica, Wungki Park, Michael H Roehrl, Jorge S Reis-Filho, Diana Mandelker, Eileen M O'Reilly> ;NPJ Precision Oncology. 2023 Apr 22
• 22 citations
  The 2022 Report on the Human Proteome from the HUPO Human Proteome Project.
  Gilbert S Omenn, Lydie Lane, Christopher M Overall, Charles Pineau, Nicolle H Packer, Ileana M Cristea, Cecilia Lindskog, Susan T Weintraub, Sandra Orchard, Michael H ...> ;Journal of Proteome Research. 2023 Apr 7
• Pancreatoblastomas and mixed and pure acinar cell carcinomas share epigenetic signatures distinct from other neoplasms of the pancreas.
  Jamal K Benhamida, Monika Vyas, Atsushi Tanaka, Lu Wang, Armita Bahrami, Kerem Ozcan, Olca Basturk, Liliana Villafania, Douglas A Mata, Tony El Jabbour, Pier Selenica,...> ;Modern Pathology. 2022 Jul 1
• 23 citations
  Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.
  N Shukla, M F Levine, G Gundem, D Domenico, B Spitzer, N Bouvier, J E Arango-Ossa, D Glodzik, J S Medina-Martínez, U Bhanot, J Gutiérrez-Abril, Y Zhou, E Fiala, E Stoc...> ;Nature Communications. 2022 May 18
• 17 citations
  Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts.
  Rebecca Caeser, Jacklynn V Egger, Shweta Chavan, Nicholas D Socci, Caitlin Byrne Jones, Faruk Erdem Kombak, Marina Asher, Michael H Roehrl, Nisargbhai S Shah, Viola Al...> ;Nature Communications. 2022 Apr 19
• 7 citations
  Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer.
  Makiko Ogawa, Atsushi Tanaka, Kei Namba, Jinru Shia, Julia Y Wang, Michael H A Roehrl> ;Scientific Reports. 2022 Feb 17
• 6 citations
  A master autoantigen-ome links alternative splicing, female predilection, and COVID-19 to autoimmune diseases.
  Julia Y Wang, Michael W Roehrl, Victor B Roehrl, Michael H Roehrl> ;Journal of Translational Autoimmunity. 2022 Jan 1
• 7 citations
  An Autoantigen Atlas From Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19.
  Julia Y Wang, Wei Zhang, Victor B Roehrl, Michael W Roehrl, Michael H Roehrl> ;Frontiers in Immunology. 2022 Jan 1
• 2 citations
  Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer.
  Makiko Ogawa, Atsushi Tanaka, Kei Namba, Jinru Shia, Julia Y Wang, Michael H Roehrl> ;Frontiers in Oncology. 2022 Jan 1
• 13 citations
  Inhibition of XPO1 sensitizes small cell lung cancer to first- and second-line chemotherapy.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yuan Hao, Andrew Chow, Yingqian Zhan, Shweta S Chavan, Fathema Uddin, Viola Allaj, P. Manoj, Nisargbhai S. Shah, Josep...> ;Cancer Research. 2021 Nov 23
• 22 citations
  Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project.
  Gilbert S. Omenn, Lydie Lane, Christopher M. Overall, Young Ki Paik, Ileana M. Cristea, Fernando J. Corrales, Cecilia Lindskog, Susan T. Weintraub, Michael H.A. Roehrl...> ;Journal of Proteome Research. 2021 Oct 20
• 22 citations
  Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Zhan, Maysun Hasan, Shweta S. Chavan, Fanli Meng, Fathema Uddin, Viola Allaj, P. Manoj, Nisargbhai S. Shah, J...> ;Journal of Hematology & Oncology. 2021 Oct 16
• 193 citations
  Proteogenomic characterization of pancreatic ductal adenocarcinoma
  Liwei Cao, Chen Huang, Daniel Cui Zhou, Yingwei Hu, T. Mamie Lih, Sara R. Savage, Karsten Krug, David J. Clark, Michael Schnaubelt, Lijun Chen, Felipe da Veiga Leprevo...> ;Cell. 2021 Sep 16
• 4 citations
  A Master Autoantigen-ome Links Alternative Splicing, Female Predilection, and COVID-19 to Autoimmune Diseases
  Wang Jy, Michael W Roehrl, Victor B Roehrl, Michael H.A. Roehrl> ;Biorxiv. 2021 Aug 4
• 27 citations
  Integrated digital pathology at scale: A solution for clinical diagnostics and cancer research at a large academic medical center.
  Peter J. Schüffler, Luke Geneslaw, D Vijay K Yarlagadda, Matthew G. Hanna, Jennifer Samboy, Evangelos Stamelos, Chad M. Vanderbilt, John Philip, Marc-Henri Jean, Lorra...> ;Journal of the American Medical Informatics Association. 2021 Aug 13
• 4 citations
  An Autoantigen Profile from Jurkat T-Lymphoblasts Provides a Molecular Guide for Investigating Autoimmune Sequelae of COVID-19
  Wang Jy, Wei Zhang, Michael W Roehrl, Victor B Roehrl, Michael H.A. Roehrl> ;Biorxiv. 2021 Jul 7
• 50 citations
  Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Zhan, Maysun Hasan, Shweta S Chavan, Fanli Meng, Fathema Uddin, P. Manoj, Mark T.A. Donoghue, Helen Won, Jose...> ;Cancer Discovery. 2021 Jun 21
• 23 citations
  An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19.
  Julia Y. Wang, Wei Zhang, Michael W Roehrl, Victor B Roehrl, Michael H.A. Roehrl> ;Journal of Autoimmunity. 2021 Apr 27
• 11 citations
  An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19
  Wang Jy, Wei Zhang, Victor B Roehrl, Michael W Roehrl, Michael H.A. Roehrl> ;Biorxiv. 2021 Apr 6
• 7 citations
  An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19
  Julia Y. Wang, Wei Zhang, Michael W Roehrl, Victor B Roehrl, Michael H.A. Roehrl> ;Biorxiv. 2021 Feb 22
• 19 citations
  An Autoantigen Atlas from Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19
  Wang Jy, Wei Zhang, Michael W Roehrl, Victor B Roehrl, Michael H.A. Roehrl> ;Biorxiv. 2021 Jan 24
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