MichaelRosenMDMSCI

PubMed

• Real-world effectiveness of ustekinumab and vedolizumab in TNF-exposed pediatric patients with ulcerative colitis.
  Perseus V Patel, Amy Zhang, Balu Bhasuran, Vignesh G Ravindranath, Melvin B Heyman, Sofia G Verstraete, Atul J Butte, Michael J Rosen, Vivek A Rudrapatna> ;Journal of Pediatric Gastroenterology and Nutrition. 2024 Mar 14
• 1 citations
  Recommendations for Standardizing MRI-based Evaluation of Perianal Fistulizing Disease Activity in Pediatric Crohn's Disease Clinical Trials.
  Eileen Crowley, Christopher Ma, Leonard Guizzetti, Guangyong Zou, Peter J Lewindon, Michael S Gee, Jeffrey S Hyams, Michael J Rosen, Daniel von Allmen, Anthony de Buck...> ;Inflammatory Bowel Diseases. 2024 Mar 1
• 2 citations
  Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
  Kathryn Clarkston, Rebekah Karns, Anil G Jegga, Mihika Sharma, Sejal Fox, Babajide A Ojo, Phillip Minar, Thomas D Walters, Anne M Griffiths, David R Mack, Brendan Boyl...> ;Journal of Crohn's & Colitis. 2022 Nov 23
• 5 citations
  Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13.
  Michael A Schumacher, Cambrian Y Liu, Kay Katada, Megan H Thai, Jonathan J Hsieh, Britany J Hansten, Amanda Waddell, Michael J Rosen, Mark R Frey> ;Cellular and Molecular Gastroenterology and Hepatology. 2023 Jan 1
• 7 citations
  Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis.
  Kaitlin G Whaley, Ye Xiong, Rebekah Karns, Jeffrey S Hyams, Subra Kugathasan, Brendan M Boyle, Thomas D Walters, Judith Kelsen, Neal LeLeiko, Jason Shapiro, Amanda Wad...> ;Clinical Gastroenterology and Hepatology. 2023 May 1
• 4 citations
  Identification of Immunoglobulin G Autoantibody Against Malondialdehyde-Acetaldehyde Adducts as a Novel Serological Biomarker for Ulcerative Colitis.
  Michael J Duryee, Rizwan Ahmad, Derrick D Eichele, Carlos D Hunter, Ananya Mitra, Geoffrey A Talmon, Shailender Singh, Lynette M Smith, Michael J Rosen, Punita Dhawan,...> ;Clinical and Translational Gastroenterology. 2022 Apr 1
• 14 citations
  Antibodies-to-infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease.
  Ruben J Colman, Ye Xiong, Tomoyuki Mizuno, Jeffrey S Hyams, Joshua D Noe, Brendan Boyle, Geert R D'Haens, Johan van Limbergen, Kelly Chun, Jane Yang, Michael J Rosen, ...> ;Alimentary Pharmacology & Therapeutics. 2022 Mar 1
• Controversies in Abdominal Wall Reconstruction.
  Kevin F. Baier, Michael J. Rosen> ;The Surgical Clinics of North America. 2021 Dec 1
• 1 citations
  A pragmatic, evidence-based approach to coding for abdominal wall reconstruction
  Benjamin K. Poulose, Li-Ching Huang, Sharon Phillips, J. Greenberg, William W. Hope, R. Janczyk, F. Malcher, Arielle J. Perez, R. A. Petersen, Ajita S. Prabhu, Michael...> ;Hernia. 2021 Oct 30
• 1 citations
  New Role for Fatty Acid Receptor Regulation of Immune Cells to Control Intestinal Inflammation.
  Michael J. Rosen> ;Gastroenterology. 2021 Oct 18
• 7 citations
  Vedolizumab Experience in Children and Adolescents With Inflammatory Bowel Disease: A Multicenter Observational Study.
  Temara M Hajjat, Maua Mosha, Kaitlin G Whaley, Michael J Rosen, Carmine Suppa, James Markowitz, Lauren Dufour, Cary Sauer, Monica Shukla-Udawatta, Brendan Boyle, Megha...> ;Crohn's & Colitis 360. 2021 Jul 1
• 15 citations
  Favorable Outcomes and Anti-TNF Durability After Addition of an Immunomodulator for Anti-Drug Antibodies in Pediatric IBD Patients.
  Ruben J. Colman, Andrea Portocarrero-Castillo, Deepika L. Chona, Jennifer Hellmann, Phillip Minar, Michael J. Rosen> ;Inflammatory Bowel Diseases. 2021 Mar 15
• 5 citations
  Understanding the benefits of botulinum toxin A: retrospective analysis of the Abdominal Core Health Quality Collaborative.
  Charlotte M. Horne, V. Augenstein, F. Malcher, J. Yunis, L. C. Huang, S. J. Zolin, Aldo Fafaj, Jonah D. Thomas, David M. Krpata, Clayton C. Petro, Michael J. Rosen, Aj...> ;The British Journal of Surgery. 2021 Mar 12
• 3 citations
  Utilization of a quality reporting system to increase faculty participation in resident operative assessment.
  Robert Naples, Judith C. French, Jonah D. Thomas, Cathleen Khandelwal, Michael J. Rosen, Jeremy M. Lipman> ;Surgery. 2021 Mar 1
• 25 citations
  Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
  Michael A. Schumacher, Jonathan J. Hsieh, Cambrian Y. Liu, Keren Appel, Amanda Waddell, Dana Almohazey, Kay Katada, Jessica K. Bernard, Edie B Bucar, Safina Gadeock, K...> ;Nature Communications. 2021 Feb 5
• 7 citations
  The European Hernia Society classification applied to the rare cases of parastomal hernia after ileal conduit urinary diversion: a retrospective cohort of 96 patients.
  J S Su, Nathan Y. Hoy, Aldo Fafaj, Luciano Tastaldi, Andrew T. Strong, Michael J. Rosen, J Li, Hadley M. Wood> ;Hernia. 2021 Feb 1
• 31 citations
  Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease.
  Ye Xiong, Tomoyuki Mizuno, Ruben J. Colman, Jeffrey S. Hyams, Joshua D. Noe, Brendan M. Boyle, Yi-Ting Tsai, Min Dong, Kimberly Jackson, Nieko Punt, Michael J. Rosen, ...> ;Clinical Pharmacology and Therapeutics. 2021 Jun 1
• 9 citations
  Management of ventral hernia defect during enterocutaneous fistula takedown: practice patterns and short-term outcomes from the Abdominal Core Health Quality Collabora...
  Aldo Fafaj, Luciano Tastaldi, Hemasat Alkhatib, S. J. Zolin, Steven Rosenblatt, Li-Ching Huang, Sharon Phillips, David M. Krpata, Ajita S. Prabhu, Clayton C. Petro, Mi...> ;Hernia. 2021 Jan 2
• 28 citations
  Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer
  Sarah P. Short, Jennifer M. Pilat, Caitlyn W. Barrett, Vishruth K. Reddy, Yael Haberman, Jared Hendren, Benjamin J. Marsh, Cody E. Keating, Amy K. Motley, Kristina E. ...> ;Gastroenterology. 2021 Apr 1
• 5 citations
  Predicting Therapeutic Response in Pediatric Ulcerative Colitis-A Journey Towards Precision Medicine.
  Ruben J. Colman, Jasbir Dhaliwal, Michael J. Rosen> ;Frontiers in Pediatrics. 2021 Feb 17
• 2 citations
  Robo FOMO (Fear of Missing Out), But at What Cost? The Unintended Consequences of Robotics for General Surgery Operations at Rural Hospitals.
  Ajita S. Prabhu, Michael J. Rosen> ;Surgical Innovation. 2020 Dec 31
• 4 citations
  The Efficacy of Liposomal Bupivacaine On Postoperative Pain Following Abdominal Wall Reconstruction: A Randomized, Double-Blind, Placebo-Controlled Trial.
  Aldo Fafaj, David M. Krpata, Clayton C. Petro, Ajita S. Prabhu, Steven Rosenblatt, Luciano Tastaldi, Hemasat Alkhatib, Chao Tu, Samuel J. Zolin, Jonah D. Thomas, Adele...> ;Annals of Surgery. 2020 Dec 2
• 17 citations
  Registry-Based Randomized Controlled Trials: A New Paradigm for Surgical Research.
  Samuel J. Zolin, Clayton C. Petro, Ajita S. Prabhu, Aldo Fafaj, Jonah D. Thomas, Charlotte M. Horne, Luciano Tastaldi, Hemasat Alkhatib, David M. Krpata, Steven Rosenb...> ;The Journal of Surgical Research. 2020 Nov 1
• 42 citations
  Patient-Reported Outcomes of Robotic vs Laparoscopic Ventral Hernia Repair With Intraperitoneal Mesh: The PROVE-IT Randomized Clinical Trial.
  Clayton C. Petro, S. J. Zolin, David M. Krpata, Hemasat Alkhatib, Chao Tu, Michael J. Rosen, Ajita S. Prabhu> ;JAMA Surgery. 2020 Oct 21
• 2 citations
  Could a Small Population of Epithelial Cells Get "Tuft" With Crohn's Disease?
  Michael J. Rosen> ;Gastroenterology. 2020 Oct 1
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Journal Articles

• Mucosal type 2 and type 17 gene expression distinguishes ulcerative colitis from colon-only Crohn�s disease in treatment-na�ve pediatric patients  
  Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Collins MH, Haberman Y, Minar P, Baldassano RN, Hyams JS, Baker SS, Kellermayer R, Noe J, Griffiths AM, Rosh JR, C..., Gastroenterology, 1/1/2017
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  Liu Z, Kong F, Vallance JE, Harmel-Laws E, Amarachintha S, Steinbrecher KA, Rosen MJ, Bhattacharyya S., Physiological Reports., 1/1/2017
• Microbiota-sensitive epigenetic signature predicts inflammation in Crohn�s disease  
  Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, H..., JCI Insight, 1/1/2017
• A Low Neutrophil CD64 Index Is Associated with Sustained Remission During Infliximab Maintenance Therapy  
  Minar P, Jackson K, Tsai YT, Rosen MJ, Northcutt M, Khodoun M, Finkelman FD, Denson LA., Inflamm Bowel Dis., 1/1/2016
• Review Article: Applying Pharmacokinetics to Optimize Dosing of Anti-TNF Biologics in Acute Severe Ulcerative Colitis  
  Rosen MJ, Minar P, Vinks AA., Alimentary Pharmacology and Therapeutics., 1/1/2015
• IL-33 signaling protects from murine oxazolone colitis by supporting intestinal epithelial function  
  Waddell A, Vallance JE, Moore PD, Hummel AT, Shanmukhappa SK, Wu D, Fei L, Washington MK, Minar P, Coburn L, Nakae S, Wilson KT, Denson LA, Hogan SP, Rosen MJ., Inflammatory Bowel Diseases, 1/1/2015
• Small intestinal intraepithelial TCRgammadelta lymphocytes Are Present in the Premature Intestine but Selectively Reduced in Surgical Necrotizing Enterocolitis  
  Weitkamp JH, Rosen MJ, Zhiguo Z, Koyama T, Denning TL, Rock MT, Moore DJ, Matta P, Denning PW., PLOS One, 1/1/2014
• Endoscopic diagnosis of duodenal stenosis in a 5-month-old male infant  
  Nicholson MR, Acra SA, Chung DH, Rosen MJ, Clinical Endoscopy, 1/1/2014
• Appendicitis after Colonoscopy  
  Rosen MJ, Sands BE., Journal of Clinical Gastroenterology, 1/1/2005
• Inflammatory Bowel Disease in Children and Adolescents  
  Rosen MJ, Dhawan A, Saeed SA, JAMA Pediatrics
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Abstracts/Posters

• The treatment na�ve rectal transcriptome identifies pathways mediating clinical and endoscopic severity and response to initial therapy in pediatric ulcerative colitis.
  Haberman Y, Karns R, Dexheimer PJ, Bauman LE, Collins MH, Rosen MJ, et al., AGA Annual Scientific Meeting at DDW, Washington, DC, 1/1/2018
• IL-33 indirectly induces goblet cell hyperplasia in the murine intestine through IL-13 production by type 2 innate lymphoid cells.
  Waddell AP, Vallance JE, Rosen MJ., AGA Abstracts published in Gastroenterology, 1/1/2017
• Effect of an Anti-TNF Therapeutic Drug Monitoring Quality Improvement Program on Inflammatory Bowel Disease Patient Outcomes at a Large Academic Pediatric Gastroentero...
  Mulgund AA, Bauman L, Chona DL, Sharma P, Su W, Fei L, Denson LA, Minar P, Dykes DM, Rosen MJ., World Congress of Gastroenterology at ACG, NASPGHAN Annual Scientific Meeting, 1/1/2017
• The Self-Management Transition Enhancement Program (STEP): Study Design and Preliminary Findings
  Grey W, Morgan P, Holbrook E, Rosen M, Yacyshyn B, Wise C, Wagoner S, Schaefer M, Saeed S, Denson L, Mackner L, Maddux M, Hommel K., CCFA Advances in Inflammatory Bowel Disease, 1/1/2016
• IL-33 signaling augments epithelial barrier function in vitro and protects mice from oxazolone colitis.
  Waddell A, Vallance JE, Moore PD, Hummel AT, Shanmukhappa SK, Washington MK, Nakae S, McKenzie ANJ, Wilson KT, Denson LA, Hogan SP, Rosen MJ., AGA Annual Scientific Meeting at Digestive Diseases Week, 1/1/2015
• Loss of MTG 16 Results in a Pro-Tumorigenic Inflammatory Microenvironment.
  Naik RD, McDonough E, Barrett C, Parang B, Bradley A, Choksi YA, Ning W, Poindexter S, Fischer M, Chaturvedi R, Ravetta F, Washington MK, Rosen MJ, Wilson KT, Williams..., AGA Annual Scientific Meeting at Digestive Diseases Week, 1/1/2014
• Colon Mucosal Signal Transducer and Activator of Transcription (STAT) Protein Activation Profiles in Pediatric Inflammatory Bowel Disease.
  Falaiye TO, Washington MK, Moulton DE, Kuhnhein LA, Moore PD, Wilson KT, Rosen MJ., AGA Annual Scientific Meeting at Digestive Diseases Week, 1/1/2013
• Prospective Randomized Trial of a Progressive Pediatric to Adult Transition of Care Program in Adolescents with Inflammatory Bowel Disease.
  Moulton DE, Rosen MJ, Beaulieu DB, Horst SN, Schwartz DA, AGA Annual Meeting at Digestive Diseases Week, 1/1/2013
• STAT6 contributes to sustaining oxazolone-induced colitis in mice
  Rosen MJ, Washington MK, Chaturvedi R, Coggeshall SS, Kuhnhein LA, Moore PD, Singh AB, Van Kaer L, Wilson KT., AGA Annual Scientific Meeting at Digestive Diseases Week, 1/1/2012
• STAT6 deficiency attenuates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines.
  Rosen MJ, Chaturvedi R, Washington MK, Kuhnhein LA, Moore PD, Coggeshall, SS, McDonough EM, Weitkamp JH, Singh AB, Coburn LA, Williams CS, Kaer LV, Peebles RS, Wilson KT., NASPGHAN Meeting, 1/1/2012
• Outcome Following Infliximab Therapy for Pediatric Patients Hospitalized with Severe Colitis.
  Falaiye TO, Mitchell KR, Lu Z, Saville BR, Horst SN, Beaulieu DB, Moulton DE, Schwartz DA, Wilson KT, Rosen MJ., Inflammatory Bowel Diseases (Advances in Inflammatory Bowel Diseases Crohn's & Colitis Foundation's Research & Clinical Conference Abstract Supplement), 1/1/2012
• IL-13-induced colon epithelial cell apoptosis and barrier dysfunction is STAT6 dependent.
  Rosen MJ, Kuhnhein LA, Coggeshall SS, Chaturvedi R, Frey MR, Matta P, Polk DB, Wilson, KT, AGA Annual Scientific Meeting at Digestive Diseases Week, 1/1/2011
• Biologic and Immunomodulator Therapy Improves Depressive Symptoms in Subjects with Inflammatory Bowel Disease.
  Horst SN, Gaines L, Rosen MJ, Beaulieu D, Schwartz DA, AGA Annual Meeting at Digestive Diseases Week, 1/1/2011
• Pediatric Crohn�s Disease Presenting as Upper Gastrointestinal Obstruction
  Falaiye T, Warolin J, Martinez JA, Gillis L, Arthur C, Acra S, Moulton DE, Rosen MJ., NASPGHAN Annual Meeting., 1/1/2011
• 15-year-old girl with chronic atrophic gastritis and enterochromaffin-like cell hyperplasia.
  Russell AC, Black JO, Schwartz DA, Correa H, Rosen MJ., NASPGHAN Annual Meeting, 1/1/2010
• STAT6 activation in ulcerative colitis: A target for prevention of IL-13-induced colonic epithelial cell dysfunction.
  Rosen MJ, Washington MK, Polk DB., Gastroenterology, 1/1/2009
• Role of SAHA for preventing IL-13-induced colon epithelial cell dysfunction
  Rosen MJ, Frey MR, Washington MK, Polk DB, Advances in Inflammatory Bowel Diseases Crohn's & Colitis Foundation's Research & Clinical Conference, 1/1/2009
• Endoscopic Ultrasound to Guide the Combined Medical and Surgical Management of Pediatric Perianal Crohn�s Disease: A Single-Center Five-Year Experience.
  Rosen MJ, Moulton DE, Koyama T, Morgan WM, Morrow SE, Herline AJ, Muldoon RL, Wise PE, Polk DB, Schwartz DA., American College of Gastroenterology 73rd Annual Scientific Meeting., 1/1/2008
• Endoscopic Ultrasound to Guide Management of Pediatric Perianal Crohn�s Disease: A Single-Center Five-Year Experience.
  Rosen MJ, Moulton DE, Koyama T, Morgan WM, Morrow SE, Herline AJ, Muldoon RL, Wise PE, Polk DB, Schwartz DA, NASPGHAN Annual Meeting., 1/1/2008
• The Use of Endoscopic Ultrasound in Pediatric Patients with Perianal Crohn's Disease.
  Rosen MJ, Moulton D, Little C, et al., Gastroenterology, 1/1/2007
• A Randomized Prospective Trial of Endoscopic Ultrasound to Guide Combination Medical and Surgical Treatment for Crohn�s Perianal Fistulas
  Spradlin NM, Wise P, Herline A, Muldoon R, Rosen M, Schwartz DA, American College of Gastroenterology 72nd Annual Scientific Meeting, 1/1/2007
• ASCA Positivity is associated with increased risk for early surgery in Crohn's disease
  Forcione DG, Rosen MJ, Kisiel JB, Sands BS, American College of Gastroenterology 68th Annual Scientific Meeting, 1/1/2003
• Increased mucosal type 2 and type 17 gene expression distinguishes ulcerative colitis from colitis-only Crohn�s disease in treatment-na�ve pediatric patients.
  Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Haberman Y, Minar P, Wilson KT, Hogan SP, Denson LA, RISK Study Group., World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, 1/8./2016
• Refined population pharmacokinetic model for infliximab precision dosing in pediatric inflammatory bowel disease.
  Bauman LE, Xiong Ye, Mizuno T, Fukuda T, Dong M, Rosen MJ, Vinks AA, Crohn�s & Colitis Congress Abstracts in Gastroenterol
• Circulating Interleukin 10 (IL10) and MIP-3alpha (CCL20) Segregates Liver Disease from Transient Elevation of Liver Enzymes in a Discovery Cohort of Pediatric Ulcerati...
  Lam S, Squires JE, Rosen MJ, Su W, Fei L, Zhang W, Setchell KDR, Denson LA, Hyams JS, Miethke AG, Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Hepatology, San Francisco, CA, 1/9./2018
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Lectures

• Cases from the Wards 
  Children�s Hospital Boston - 1/1/2005
• Interleukin-33 in Ulcerative Colitis: Pro-Inflammatory Cytokine or Protective Response 
  Cincinnati, OH - 1/10/2015
• Mucosal type 2 and type 17 gene expression distinguishes ulcerative colitis from colitis-only Crohn�s disease in treatment-na�ve pediatric patients 
  Mt. Sterling, OH - 1/9./2016
• Immune cell regulation of intestinal epithelial differentiation 
  1/16/2018
• Cell-specific Transcriptome Dysregulation across the Inflammatory Front Line in Ulcerative Colitis 
  Cincinnati, OH - 1/11/2018
• Ulcerative Colitis: Current Concepts of Pathogenesis 
  St. Louis, MO - 1/14/2009
• STAT6 Signaling in Ulcerative Colitis 
  New Orleans, LA - 1/22/2010
• Th Who? The Role of Th2 Inflammation in Pediatric Inflammatory Bowel Disease 
  Cincinnati Children�s Hospital Medical Center Digestive Health Center - 1/6./2011
• Take 2: Th2 Inflammation in Pediatric IBD 
  Emory University, Division of Pediatric Gastroenterology, Hepatology, and Nutrition - 1/31/2012
• Progress and Challenges in Pediatric Inflammatory Bowel Disease Research 
  1/17/2012
• Getting your Manuscript Published 
  1/17/2013
• Th2 Cytokines and Signaling in Pediatric IBD 
  Weill Cornell Medicine - 1/17/2015
• What�s Next in Treatments for Pediatric Inflammatory Bowel Disease 
  1/16/2016
• A Tale of the Sponge, the Shark, and the Sieve: Optimizing Anti-TNF Therapy for Acute Severe Ulcerative Colitis 
  1/11/2016
• When Can We Use Genetic Testing in Our Pediatric IBD Patients 
  1/10/2016
• Imaging of Pediatric Crohn�s Disease: What the Pediatric Gastroenterologist Wants to Know 
  1/15/2017
• Translational Advances in Pediatric IBD � How Will It Affect My Practice? 
  1/18/2018
• Type 2 Inflammation in Pediatric Inflammatory Bowel Disease 
  Children�s Hospital of Fudan University - 1/9./2016
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Other

• Outcome following infliximab therapy for pediatric patients hospitalized with refractory colitis-predominant inflammatory bowel disease. 
  Falaiye TO, Mitchell KR, Lu Z, Saville BR, Horst SN, Moulton DE, Schwartz DA, Wilson KT, Rosen MJ., Biologic Treatment of Pediatric Inflammatory Bowel Disease: A Decade of JPGN Contributions
  1/1/2014