MichaelRSchlabachMDMPH

PubMed

• 188 citations
  Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss.
  Huayang Liu, Javad Golji, Lauren K. Brodeur, Franklin Chung, Julie T. Chen, Rosalie deBeaumont, Caroline Bullock, Michael D. Jones, Grainne Kerr, Li Li, Daniel P. Raki...> ;Nature Medicine. 2019 Jan 1
• 38 citations
  TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.
  Robert M. Witwicki, Muhammad B. Ekram, Xintao Qiu, Michalina Janiszewska, Shaokun Shu, Mijung Kwon, Anne Trinh, Elizabeth Frias, Nadire Ramadan, Greg Hoffman, Kristine...> ;Cell Reports. 2018 Oct 30
• 1 citations
  Corrigendum: Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program.
  Anna E Mazzucco, Agata Smogorzewska, Chanhee Kang, Ji Luo, Michael R Schlabach, Qikai Xu, Rupesh Patel, Stephen J Elledge> ;Genes & Development. 2017 Nov 15
• 17 citations
  Correction: KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer.
  Elsa Beyer Krall, Belinda Wang, Diana M Munoz, Nina Ilic, Srivatsan Raghavan, Matthew J. Niederst, Kristine Yu, David A. Ruddy, Andrew J. Aguirre, Jong Wook Kim, Amand...> ;Elife. 2017 Oct 31
• 8 citations
  Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program.
  Anna E Mazzucco, Agata Smogorzewska, Chanhee Kang, Ji Luo, Michael R Schlabach, Qikai Xu, Rupesh Patel, Stephen J Elledge> ;Genes & Development. 2017 Oct 1
• 402 citations
  Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening
  E. Robert McDonald, Antoine de Weck, Michael R. Schlabach, Eric Billy, Konstantinos J. Mavrakis, Gregory R. Hoffman, Dhiren Belur, Deborah Castelletti, Elizabeth Frias...> ;Cell. 2017 Jul 27
• 97 citations
  KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer
  Elsa Beyer Krall, Belinda Wang, Diana M Munoz, Nina Ilic, Srivatsan Raghavan, Matthew J. Niederst, Kristine Yu, David A. Ruddy, Andrew J. Aguirre, Jong Wook Kim, Amand...> ;Elife. 2017 Feb 1
• 236 citations
  CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions
  Diana M Munoz, Pamela J. Cassiani, Li Li, Eric Billy, Joshua M. Korn, Michael D. Jones, Javad Golji, David A. Ruddy, Kristine Yu, Gregory McAllister, Antoine deWeck, D...> ;Cancer Discovery. 2016 Aug 1
• 316 citations
  Studying clonal dynamics in response to cancer therapy using high-complexity barcoding
  Hyo-eun C. Bhang, David A. Ruddy, Viveksagar Krishnamurthy Radhakrishna, Justina X. Caushi, Rui Zhao, Matthew M Hims, Angad P Singh, Iris Kao, Daniel P. Rakiec, Pamela...> ;Nature Medicine. 2015 May 1
• 64 citations
  A Chemical Genetics Approach for the Functional Assessment of Novel Cancer Genes
  Qianhe Zhou, Adnan Derti, David A. Ruddy, Daniel P. Rakiec, Iris Kao, Michelle Lira, Veronica Gibaja, Ho Man Chan, Yi Yang, Junxia Min, Michael R. Schlabach, Frank Ste...> ;Cancer Research. 2015 May 15
• 102 citations
  Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma
  Jie Li, Shan Zhu, David Kozono, Kimberly Ng, Diahnn Futalan, Ying Shen, Johnny C. Akers, Tyler Steed, Deepa Kushwaha, Michael R. Schlabach, Bob S. Carter, Chang-Hyuk K...> ;Oncotarget. 2014 Mar 2
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