MichaelG.SeneffMD

PubMed

• A residency style transition to practice program in trauma and critical care: The George Washington University Hospital experience.
  Jonathan Messing, Miranda Peters, Amy Vota, Michael G. Seneff, Babak Sarani> ;Journal of the American Association of Nurse Practitioners. 2021 Jan 8
• Medicare, Value-Based Purchasing, and the Law of Unintended Consequences.
  Mustafa Al-Mashat, Michael G. Seneff> ;Journal of Intensive Care Medicine. 2018 Jan 1
• 16 citations
  Characterization of end-of-life electroencephalographic surges in critically ill patients
  Lakhmir S. Chawla, Megan Terek, Christopher Junker, Seth Akst, Bona Yoon, Ermira Brasha-Mitchell, Michael G. Seneff> ;Death Studies. 2017 Feb 1
• 15 citations
  Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes
  Lakhmir S. Chawla, Ian Toma, Danielle Davison, Khashayar Vaziri, Juliet Lee, Raymond Lucas, Michael G. Seneff, Aobhinn Nyhan, Timothy A. McCaffrey> ;BMC Medical Genomics. 2016 Jul 15
• 147 citations
  Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity
  Jay L. Koyner, Danielle Davison, Ermira Brasha-Mitchell, Divya M. Chalikonda, John M. Arthur, Andrew D. Shaw, James A. Tumlin, Sharon Trevino, Michael R. Bennett, Paul...> ;Journal of the American Society of Nephrology. 2015 Feb 5
• 117 citations
  Intravenous angiotensin II for the treatment of high-output shock (ATHOS trial): a pilot study
  Lakhmir S. Chawla, Laurence W. Busse, Ermira Brasha-Mitchell, Danielle Davison, Jacqueline Honiq, Ziyad Alotaibi, Michael G. Seneff> ;Critical Care. 2014 Oct 6
• 1 citations
  Safety and dose-finding study of activated protein C (drotrecogin alfa activated) as an anticoagulant in end-stage renal disease patients treated with hemodialysis.
  Ermira Brasha-Mitchell, Ashte Collins, Lindita Shehu, Michael G. Seneff, Samir S. Patel, Lakhmir S. Chawla> ;Blood Purification. 2014 Jan 1
• 2 citations
  End-of-life electrical surges
  Lakhmir S. Chawla, Michael G. Seneff> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Oct 29
• 214 citations
  Development and standardization of a furosemide stress test to predict the severity of acute kidney injury.
  Lakhmir S. Chawla, Danielle Davison, Ermira Brasha-Mitchell, Jay L. Koyner, John M. Arthur, Andrew D. Shaw, James A. Tumlin, Sharon Trevino, Paul L. Kimmel, Michael G....> ;Critical Care. 2013 Sep 20
• 49 citations
  A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis.
  Alejandro C. Arroliga, Robert A. Balk, Chad M. Cannon, Nathan C. Dean, Phillip Dellinger, Paula Dennen, Juan Figueroa, Eugene Fletcher, Kalpalatha K. Guntupalli, David...> ;Critical Care Medicine. 2013 Mar 1
• 1 citations
  Treatment of addison disease and subsequent hypophosphatemic respiratory failure.
  Leah Meisterling, Lakhmir S. Chawla, Michael G. Seneff> ;Journal of Intensive Care Medicine. 2012 Sep 1
• 55 citations
  Off-Pump versus On-Pump Coronary Artery Bypass Grafting Outcomes Stratified by Preoperative Renal Function
  Lakhmir S. Chawla, Yue Zhao, Fredrick C. Lough, Elizabeth Schroeder, Michael G. Seneff, J. Matthew Brennan> ;Journal of the American Society of Nephrology. 2012 Aug 1
• 34 citations
  Neurogenic Pulmonary Edema: Successful Treatment With IV Phentolamine
  Danielle Davison, Lakhmir S. Chawla, Leelie Selassie, Rahul Tevar, Christopher Junker, Michael G. Seneff> ;Chest. 2012 Mar 1
• 10 citations
  Utilization of base deficit and reliability of base deficit as a surrogate for serum lactate in the peri-operative setting
  Lakhmir S. Chawla, Amirali Nader, Todd Nelson, Trusha Govindji, Ryan Wilson, Sonia Szlyk, Aline Nguyen, Christopher Junker, Michael G. Seneff> ;BMC Anesthesiology. 2010 Sep 9
• 20 citations
  Femoral-Based Central Venous Oxygen Saturation Is Not a Reliable Substitute for Subclavian/Internal Jugular-Based Central Venous Oxygen Saturation in Patients Who Are ...
  Danielle Davison, Lakhmir S. Chawla, Leelie Selassie, Elizabeth M. Jones, Kayc C. McHone, Amy R. Vota, Christopher Junker, Sara Sateri, Michael G. Seneff> ;Chest. 2010 Jul 1
• 51 citations
  Surges of electroencephalogram activity at the time of death: a case series
  Lakhmir S. Chawla, Seth Akst, Christopher Junker, Barbara Jacobs, Michael G. Seneff> ;Journal of Palliative Medicine. 2009 Dec 8
• 2 citations
  In-hospital CPR: Performing it Better but Less Often
  Amirali Nader, Michael G. Seneff> ;Journal of Intensive Care Medicine. 2009 May 1
• 29 citations
  Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the...
  Lakhmir S. Chawla, Shirley L. Shih, Danielle Davison, Christopher Junker, Michael G. Seneff> ;BMC Emergency Medicine. 2008 Dec 16
• 24 citations
  Anion Gap, Anion Gap Corrected for Albumin, and Base Deficit Fail to Accurately Diagnose Clinically Significant Hyperlactatemia in Critically Ill Patients
  Lakhmir S. Chawla, Dhiraj Jagasia, Lynn M. Abell, Michael G. Seneff, Melinda Egan, Natale Danino, Aline Nguyen, Mazer Ally, Paul L. Kimmel, Christopher Junker> ;Journal of Intensive Care Medicine. 2008 Mar 1
• 135 citations
  Elevated Plasma Concentrations of IL-6 and Elevated APACHE II Score Predict Acute Kidney Injury in Patients with Severe Sepsis
  Lakhmir S. Chawla, Michael G. Seneff, David R. Nelson, Mark E. Williams, Howard Levy, Paul L. Kimmel, William L. Macias> ;Clinical Journal of the American Society of Nephrology. 2006 Nov 2
• 2 citations
  Comparing thermodilution and fick cardiac outputs: should I buy an edsel or a yugo?
  Michael G. Seneff> ;Journal of Intensive Care Medicine. 2006 Mar 1
• 66 citations
  Identifying critically ill patients at high risk for developing acute renal failure: a pilot study.
  Lakhmir S. Chawla, Lynn M. Abell, Ramin Mazhari, Melinda Egan, Navin Kadambi, Harry B. Burke, Christopher Junker, Michael G. Seneff, Paul L. Kimmel> ;Kidney International. 2005 Nov 1
• 8 citations
  Lactate concentration gradient from right atrium to pulmonary artery
  Guillermo Gutierrez, Lakhmir S. Chawla, Michael G. Seneff, Nevin M Katz, Hasan Zia> ;Critical Care. 2005 Jun 10
• 30 citations
  Modification of continuous venovenous hemodiafiltration with single-pass albumin dialysate allows for removal of serum bilirubin
  Lakhmir S. Chawla, Florin Georgescu, Bruce Abell, Michael G. Seneff, Paul L. Kimmel> ;American Journal of Kidney Diseases. 2005 Mar 1
• 133 citations
  Lack of Equivalence between central and mixed venous oxygen saturation.
  Lakhmir S. Chawla, Hasan Zia, Guillermo Gutierrez, Nevin M Katz, Michael G. Seneff, Muhammed Shah> ;Chest. 2004 Dec 1
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Journal Articles

• Acute Appendicitis: Transcript profiling of blood identifies promising biomarkers and potential underlying processes  
  Chawla LS, Toma IV, Davison D, Vaziri K, Lee J, Lucas R, Seneff MG, Nyhan A, McCaffrey T, BMC Med Genomics, 1/1/2016
• Furosemide stress test and biomarkers for the prediction of AKI severity  
  Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS, J Am Soc Nephrol, 1/1/2015
• Safety and dose-finding study of activated protein C (Drotrecogin Alafa Activated) as an anticoagulant in end-stage renal disease patients treated with hemodialysis  
  Brasha-Mitchell E, Collins A, Shehu L, Seneff MG, Patel SS, Chawla LS, Blood Purif, 1/1/2014
• Intravenous Angiotensin II for the treatment of high-output shock (ATHOS) trial: a pilot study  
  Chawla LS,, Busse L, Brasha-Mitchell E, Davison D, Honig J, Alotaibi Z, Seneff MG, Critical Care, 1/1/2014
• Development and standardization of a furosemide stress test to predict the severity of acute kjdney injury  
  Chawla LS, Davison DL, Brasha-Mitchell E, Koyner JL, Shaw AD, Trevino S, Kimmel PL, Seneff MG, Critical Care, 1/1/2013
• End-Of-Life electrical surges  
  Chawla L, Seneff MG, Proc Natl Acad Sci, 1/1/2013
• Treatment of Addison Disease and subsequent hypophosphatemic respiratory failure  
  Meisterling L, Chawla LS, Seneff MG, J Intens Care Med, 1/1/2012
• Off-pump versus on-pump coronary bypass grafting outcomes stratified by preoperative renal function  
  Chawla LS, Zhao Y, Lough FC, Schroeder E, Seneff MG, Brennan JM, J Am Soc Nephrol, 1/1/2012
• Utilization of base deficit and reliability of base deficit as a surrogate for serum lactate in the peri-operative setting  
  Chawla LS, Nader A, Nelson T, Govindji T, Wilson R, Szlyk S, Nguyen A, Junker C, Seneff MG, BMC Anesthesiology, 1/1/2010
• Surges of Electroencephalogram activity at the time of death: A case series  
  Chawla LS, Akst S, Junker C, Jacobs B, Seneff MG, J Palliative Medicine, 1/1/2009
• In-hospital CPR: Performing it better but less often  
  Nader A, Seneff MG, J. Intensive Care Med, 1/1/2009
• International integrated database for the evaluation of severe sepsis(INDEPTH): clinical Evaluation committee report on the safety of dotrecogin alfa (activated) Therapy  
  Dhainaut JF and the INDEPTH Clinical Evaluation Committee, Curr Med Res Opin, 1/1/2008
• Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the...  
  Chawla LS, Shih S, Davison DL, Junker C, Seneff MG, BMC Emergency Medicine, 1/1/2008
• Elevated plasma concentration of IL-6 and elevated APACHEII score predict acute kidney injury in patients with severe sepsis  
  Chawla LS, Seneff MG, Nelson DR, et al, J Am Soc Nephrol, 1/1/2007
• Lactate concentration gradient from right atrium to pulmonary artery  
  Gutierrez G, Chawla LS, Seneff MG, Katz NM, Zia H, Critical Care, 1/1/2005
• Identifying critically ill patients at high risk for developing acure renal failure:A pilot study  
  Chawla LS, Abell L, Mazhari R, Egan M, Kadambi N, Burke HB, Junker C, Seneff MG, Kimmel PL, Kidney Int, 1/1/2005
• In Response for the Editors  
  Seneff MG, J Intens Care Med, 1/1/2005
• Alice in ICULand: In resuscitation, timimg is key  
  Gutierrez G, Seneff M, J. Intensive Care, 1/1/2003
• The impact of long term acute care (LTAC) facilities on the outcome and cost of care for patients undergoing prolonged mechanical ventilation  
  Seneff MG, Thompson D, Wagner D, Honeycutt C, Silver M, Crit Care Med, 1/1/2000
• Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, doubleblind, placebo-controlled, multicenter trial  
  Opal SM, Fisher CJ, Dhainaut JFA, Seneff MG, et al. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group, Crit Care Med, 1/1/1997
• Using the APACHE III system to improve the quality of intensive care  
  Seneff MG, Zimmerman JE, Knaus WA, Brit J Intensive Care, 1/1/1997
• Intensive care unit admissions with cirrhosis: Risk stratifying patient groups and predicting individual survival  
  Zimmerman JE, Wagner DP, Seneff MG, Becker RB, Sun X, Knaus WA, Hepatology, 1/1/1996
• Predicting the duration of mechanical ventilation: The importance of disease and patient characteristics  
  Seneff MG, Zimmerman JE, Knaus WA, Wagner DP, Draper EA, Chest, 1/1/1996
• Facilitation of internal jugular venous cannulation using an audio-guided Doppler ultrasound device: Results from a prospective,dual center, randomized, crossover clin...  
  Gilbert TB, Seneff MG, Becker RB, Crit Care Med, 1/1/1995
• The use of Apache III to evaluate ICU length of stay, resource use, and mortality after coronary artery by-pass surgery  
  Becker RB, Zimmerman JE, Knaus WA, Wagner DP, Seneff MG, Draper EA, Higgins TL, Estafanous FG, Loop FD, J Cardiovasc Surg, 1/1/1995
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Books/Book Chapters

• Trauma Critical Care 
  Chapter: Indwelling vascular catheter-related infection and sepsis. 
  Page 863 - 871Seneff MG, Senel ACEditors: Wilson W, Grande CM, Hoyt DB.Informa Healthcare, New York2007
• Arterial line placement and care. 
  Chapter: Severity of illness indices and outcome prediction: Development and evaluation. 
  Seneff MG, Zimmerman JE, Knaus WAEditors: Ayres SM, Grenvik A, Holbrook PR, Shoemaker WC.W.B. Saunders Company, Philadelphia1995
• Textbook of Critical Care 
  Chapter: Outcome prediction for specific conditions. 
  Page 1808 - 1816Seneff MG, Zimmerman JE, Knaus WAEditors: Ayres SM, Grenvik A, Holbrook PR, Shoemaker WC.W.B. Saunders Company, Philadelphia1995
• Procedures and Techniques in Intensive Care Medicine 
  Chapter: Central venous catheters. 
  Page 15 - 35Seneff MGEditors: Rippe JM, Irwin RS, Fink MP, Cerra FB, Curley FJ, Heard SO.Little Brown & Co., Boston1994
• Procedures and Techniques in Intensive Care Medicine 
  Chapter: Arterial line placement and care. 
  Page 36 - 47Seneff MGEditors: Rippe JM, Irwin RS, Fink MP, Cerra FB, Curley FJ, Heard SO.Little Brown & Co., Boston1994
• Intensive Care Medicine 
  Chapter: Arterial line placement and care. 
  Page 37 - 47Seneff MGEditors: Rippe JM, Irwin RS, Alpert JS, Fink M.Little Brown & Co., BostonEdition 2nd,1991
• Intensive Care Medicine 
  Chapter: Central venous catheters. 
  Page 16 - 33Seneff MG, Rippe JSEditors: Rippe JM, Irwin RS, Alpert JS, Dalen JE.Little Brown & Co., Boston1985
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Abstracts/Posters

• A rare case of Langerhans Cell Histiocytosis and Hemophagocytic Lymphohistiocytosis.
  Gautam, Samir; Dhaybi, Omar; Maaty, Nancy; Seneff, Michael; Davison, Danielle, Critical Care Medicine, Society of Critical Care Medicine, Orlando, FL, 2016, 1/1/2015
• Development and standardisation of a furosemide stress test to predict the severity of acute kidney injury.
  Chawla LS, Davison DL, Brasha-Mitchell E, Koyner JL, Arthur JM, Tumlin JA, Shaw AD, Trevino S, Kimmel PL, Seneff MG, Crit Care, 1/20/2013
• REffect of Off-Pump versus on-pump CABG in patients with chronic kidney disease.
  Schroeder E, Chawla LS, Zhao Y, Lough F, Seneff MG, Brennan M, ESICM, Berlin, 1/1/2012
• Intravascular heat exchange femoral catheters and deep vein thrombosis.
  Vota A, Honig J, Chawla L, Satalin M, Jones E, Seneff MG, Crit Care Med, 1/1/2012
• Reliable detection of peripheral decoupling leads to improved cardiac output accuracy in unstable patients.
  Junker CD, Seneff MG, Chawla LS, Akst SA, Davison DL, Hatib FS, Intensive Care Med, 1/1/2011
• The impact of an antimicrobial rotation in the Intensive Care Unit on pathogen sensitivities.
  Nader A, Yohannes S, Junker C, Chawla L, Lin A, Goldwater S, Prue M, Thompson C, Davison D, Seneff M, Crit Care Med, 1/1/2007
• Pilot Study of novel indicator for detecting extreme hyperdynamic conditions in severe sepsis.
  Junker C, Seneff MG, Chawla L, Akst SA, Davison DI, Crit Care Med, 1/1/2007
• Elevated interleukin 6 and APACHE II score predicts the development of acute kidney injury in patients with severe sepsis.
  Chawla LS, Seneff MG, Williams MD, Nelson DR, Kimmel PL, Macias WL, J Am Soc Nephrol, ASN Annual Meeting, Philadelphia, PA, 1/10/2005
• Increased markers of coagulation activation as measured by plasma levels of D-dimer and protein C activity correlate with increasing levels of interleukin-6 in stable ...
  Jagasia D, Chawla LS, Sothinathan R, Seneff MG, Obeid MA, Krishnan M, Kimmel PL, J Am Soc Nephrol, ASN Annual Meeting, Philadelphia, PA, 1/10/2005
• INDEPTH Database of severe sepsis patients shows fewer cardiac events in Drotecogin Alfa (activated) patients vs placebo patients.
  Heiselman D, Lowry S, Dhainaut JF, Laterre PF, Schein R, Seneff M, et al, Chest, 1/1/2005
• Identifying critically ill patients at high risk for acute renal failure requiring renal replacement therapy.
  Chawla LS, Abell L, Mazhari R, Kadambi N, Seneff MG, Kimmel PL, J Am Soc Nephrol, American Society of Nephrology Annual Meeting, St. Louis, MO, 1/27/2004
• Acute renal failure in the ICU: Prospective modeling.
  Abell L, Kadambi N, Mazhari R, Seneff MG, Kimmel PL, Chawla LS, Am J Kid Dis, 1/1/2004
• Comparison of mixed venous oxygenation saturation measurement: Pulmonary proximal port versus distal port sampling.
  Zia HA, Chawla LS, Seneff MG, Senel AC, Gutierrez G, Crit Care Med, 1/1/2003
• Saturation difference between central and mixed venous blood as a marker of cardiac energy metabolism.
  Zia HA, Chawla LS, Seneff MG, Gutierrez G, Am J Resp Crit Care Med, 1/1/2003
• Prospectively predicting which patients develop acute renal failure in the ICU using risk factor profiling.
  Chawla LS, Mazhari R, Seneff MG, Amarsinghe A, Kimmel PL, J Am Soc Nephrol, 1/1/2003
• Improving ICU utilization by decreasing the frequency of admission and length of stay for low-risk monitor patients.
  Seneff MG, Zimmerman JE, Bojanowski, L, SCCM 28th Educational and Scientific Symposium, San Francisco, CA, 1/1/1999
• The microbiology of patients with AIDS admitted to the intensive care unit: The importance of bacterial infection.
  Rosenberg AL, Atiyeh L, Seneff MG, Wagner R, Zimmerman JE, 4th Conference on Retroviruses and Opportunistic Infections, Washington, DC, 1/22/1997
• Critical care for patients with AIDS: The increasing importance of sepsis.
  Rosenberg AL, Seneff MG, Bojanowski LA, Zimmerman JE, Crit Care Med, 1/1/1997
• Differences in hospital mortality and resource use for ICU admissions over a 5 year period.
  Rosenberg AL, Zimmerman JE, Seneff MG, Wagner D, Shonk C, Draper EA, Crit Care Med, 1/1/1997
• Variations in ICU laboratory testing: The impact of patient and institutional characteristics.
  Seneff MG, Zimmerman JE, Wagner DP, Sun X, Knaus WA, Crit Care Med, 1/1/1996
• 31P-NMR comparison studies of erythocyte and circulating ionized magnesium concentrations in critically ill patients.
  Thompson D, Laughlin M, Seneff MG, Salem M, Crit Care Med, 1/1/1996
• Thrombotic complications following femoral vein catheterization.
  Healy B, Seneff MG, Massarin E, Williams JF, Zimmerman JE, Crit Care Med, 1/1/1995
• Daily outcome estimates for patients with advanced malignancy and respiratory failure.
  Becker RB, Zimmerman JE, Wagner DP, Seneff MG, Knaus WA, Crit Care Med, 1/1/1995
• Individual prognostic estimates for patients with cirrhosis who receive mechanical ventilation.
  Zimmerman JE, Wagner DP, Seneff MG, Becker RB, Knaus WA, Crit Care Med, 1/1/1995
• Prognosis in nontraumatic coma: Identifying high risk patients using daily prognostic estimates for mortality.
  Seneff MG, Wagner DP, Zimmerman JE, Becker RB, Knaus WA, Crit Care Med, 1/1/1995
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Other

• Assessing patient outcomes as an indicator of quality of care. 
  Seneff MG, Knaus WA, Pathways in Critical Care
  1/1/1994
• Outcome prediction in intensive care. 
  Zimmerman JE, Knaus WA, Seneff MG, Intens Care Rounds
  1/1/1993
• APACHE: A prognostic scoring system. 
  Seneff MG, Knaus WA, Problems in Critical Care
  1/1/1989