MichaelGSpigarelliMD

Internal Medicine • Salt Lake City, UT

Adolescent Medicine

Professor, Pediatrics, University of Utah School of Medicine

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Office
50 N Medical Dr
Salt Lake City, UT 84132
Phone+1 801-585-2150

Fax+1 801-585-9410
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Education & Training

Cincinnati Children's Hospital Medical CenterFellowship, Adolescent Medicine, 2000 - 2002
University of Michigan Health SystemResidency, Internal Medicine/Pediatrics, 1996 - 2000
University of Michigan Medical SchoolClass of 1996

Certifications & Licensure

UT State Medical License 2010 - 2026
OH State Medical License 2000 - 2026
MI State Medical License 1996 - 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Adolescent Medicine

Awards, Honors, & Recognition

Fellow (FAAP) American Academy of Pediatrics

Clinical Trials

Epiduo Pediatric Acne Study Start of enrollment: 2010 Jun 01
Completed
Phase 4
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care Start of enrollment: 2011 Nov 01
Completed
Monitoring the Peripheral Intravenous Infusion Site for Infiltration and Extravasation Start of enrollment: 2011 Aug 01
Completed
Safety and Acceptability of Tenofovir 1% Gel in Adolescent Females
Withdrawn
Phase 1
Cannabidiol (CBD) to 27 Patients (Aged 2 Years - 19 Years) With Drug Resistant Epilepsy Start of enrollment: 2014 Sep 18
Completed
Phase 1
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Publications & Presentations

PubMed

20 citations
Diagnostic performance of kSORT, a blood-based mRNA assay for noninvasive detection of rejection after kidney transplantation: A retrospective multicenter cohort study.
Elisabet Van Loon, Magali Giral, Dany Anglicheau, Evelyne Lerut, Valérie Dubois, Maud Rabeyrin, Sophie Brouard, Silke Roedder, Michael G. Spigarelli, Marion Rabant, Kr...> ;American Journal of Transplantation. 2021 Feb 1
8 citations
Use of Oxandrolone to Promote Growth in Neonates following Surgery for Complex Congenital Heart Disease: An Open-Label Pilot Trial
Phillip T. Burch, Michael G. Spigarelli, Linda M. Lambert, Patrick D. Loftus, Catherine M.T. Sherwin, Matthew W. Linakis, Xiaoming Sheng, L. LuAnn Minich, Richard V. W...> ;Congenital Heart Disease. 2016 Jun 3
12 citations
Statewide analysis of missed opportunities for human papillomavirus vaccination using vaccine registry data.
Deanna Kepka, Michael G Spigarelli, Echo L Warner, Yukiko Yoneoka, Nancy McConnell, Alfred Balch> ;Papillomavirus Research. 2016 Dec 1
25 citations
A propensity-matched cohort study of vancomycin-associated nephrotoxicity in neonates.
Jonathan E. Constance, Alfred H. Balch, Chris Stockmann, Matthew W. Linakis, E. Kent Korgenski, Jessica K. Roberts, Robert M. Ward, Catherine M.T. Sherwin, Michael G. ...> ;Archives of Disease in Childhood. Fetal and Neonatal Edition. 2016 May 1
30 citations
Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites
Tian Yu, Sarah C. Campbell, Chris Stockmann, Casey R. Tak, Katherine Schoen, Erin A.S. Clark, Michael W. Varner, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Journal of Clinical Pharmacology. 2016 May 1
7 citations
Renal Function Descriptors in Neonates: Which Creatinine-Based Formula Best Describes Vancomycin Clearance?
Jiraganya Bhongsatiern, Chris Stockmann, Tian Yu, Jonathan E. Constance, Ganesh Moorthy, Michael G. Spigarelli, Pankaj B. Desai, Catherine M.T. Sherwin> ;Journal of Clinical Pharmacology. 2016 May 1
13 citations
Therapeutic Drug Monitoring of Ganciclovir Treatment for Cytomegalovirus Infections Among Immunocompromised Children
Chris Stockmann, Catherine M.T. Sherwin, Elizabeth D. Knackstedt, Adam L. Hersh, Andrew T. Pavia, Michael G. Spigarelli> ;Journal of the Pediatric Infectious Diseases Society. 2016 Jun 1
3 citations
High school females and those with other vaccinations most likely to complete the Human Papillomavirus vaccine.
Deanna Kepka, Qian Ding, Echo L. Warner, Michael G. Spigarelli, Kathi Mooney> ;Preventive Medicine Reports. 2015 Jan 1
16 citations
Challenges Associated with Route of Administration in Neonatal Drug Delivery.
Matthew W. Linakis, Jessica K. Roberts, Anita C. Lala, Michael G. Spigarelli, Natalie J. Medlicott, David M. Reith, Robert M. Ward, Catherine M.T. Sherwin> ;Clinical Pharmacokinetics. 2016 Feb 1
17 citations
Evaluation of Vancomycin Use in Late-Onset Neonatal Sepsis Using the Area Under the Concentration-Time Curve to the Minimum Inhibitory Concentration ≥400 Target.
Jiraganya Bhongsatiern, Chris Stockmann, Jessica K. Roberts, Tian Yu, Kent Korgenski, Michael G. Spigarelli, Pankaj B. Desai, Catherine M.T. Sherwin> ;Therapeutic Drug Monitoring. 2015 Dec 1
27 citations
Special population considerations and regulatory affairs for clinical research.
Kristin N Grimsrud, Catherine M.T. Sherwin, Jonathan E. Constance, Casey R. Tak, Athena F. Zuppa, Michael G. Spigarelli, Nicole L. Mihalopoulos> ;Clinical Research and Regulatory Affairs. 2015 Jul 22
3 citations
Quantitative Assay Validation for Oxandrolone in Human Plasma Using LC–MS-MS
Matthew W. Linakis, Chris Stockmann, Sarah C. Campbell, Richard V. Williams, Phillip T. Burch, Linda M. Lambert, Catherine M.T. Sherwin, Christopher A. Reilly, Michael...> ;Journal of Analytical Toxicology. 2015 Sep 1
4 citations
Comanagement of Pediatric Depression and Obesity: A Clear Need for Evidence
Nicole L. Mihalopoulos, Michael G. Spigarelli> ;Clinical Therapeutics. 2015 Sep 1
Application of a method used to deconstruct a single dose pharmacokinetic profile from multiple dose data.
Chris Stockmann, Michael G. Spigarelli, Daniel P. Healy, Michele M. Gottschlich, Richard J. Kagan, Alfred H. Balch, Catherine M.T. Sherwin> ;Biopharmaceutics & Drug Disposition. 2015 Sep 1
6 citations
Effect of CYP3A5*3 on asthma control among children treated with inhaled beclomethasone
Chris Stockmann, Christopher A. Reilly, Bernhard Fassl, Roger Gaedigk, Flory L. Nkoy, Bryan L. Stone, Jessica K. Roberts, Derek A. Uchida, J. Steven Leeder, Catherine ...> ;The Journal of Allergy and Clinical Immunology. 2015 Aug 1
19 citations
Determination of Optimal Amikacin Dosing Regimens for Pediatric Patients With Burn Wound Sepsis.
Tian Yu, Chris Stockmann, Daniel P. Healy, Jared Olson, Stephanie Wead, Alice N. Neely, Richard J. Kagan, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Journal of Burn Care & Research. 2015 Jul 1
37 citations
Darbepoetin administration to neonates undergoing cooling for encephalopathy: a safety and pharmacokinetic trial
Mariana Baserga, Joanna C. Beachy, Jessica K. Roberts, Robert M. Ward, Robert DiGeronimo, William F. Walsh, Robin K. Ohls, Jennifer Anderson, Dennis E. Mayock, Sandra ...> ;Pediatric Research. 2015 May 21
43 citations
Predictive Performance of a Vancomycin Population Pharmacokinetic Model in Neonates
Chris Stockmann, Adam L. Hersh, Jessica K. Roberts, Jiraganya Bhongsatiern, E K Korgenski, Michael G. Spigarelli, Catherine M.T. Sherwin, Adam Frymoyer> ;Infectious Diseases and Therapy. 2015 May 22
5 citations
Population Pharmacokinetics of Darbepoetin Alfa in Conjunction with Hypothermia for the Treatment of Neonatal Hypoxic-Ischemic Encephalopathy
Jessica K. Roberts, Chris Stockmann, Robert M. Ward, Joanna C. Beachy, Mariana Baserga, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Clinical Pharmacokinetics. 2015 May 20
17 citations
National trends in the incidence, outcomes and charges of pediatric osteoarticular infections, 1997-2012.
Chris Stockmann, Kwabena Krow Ampofo, Andrew T. Pavia, Carrie L. Byington, Anne J. Blaschke, Catherine M.T. Sherwin, Michael G. Spigarelli, Adam L. Hersh> ;The Pediatric Infectious Disease Journal. 2015 Jun 1
23 citations
Optimal design in pediatric pharmacokinetic and pharmacodynamic clinical studies
Jessica K. Roberts, Chris Stockmann, Alfred H. Balch, Tian Yu, Robert M. Ward, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Paediatric Anaesthesia. 2015 Mar 1
8 citations
Development of an optimal sampling schedule for children receiving ketamine for short-term procedural sedation and analgesia
Catherine M.T. Sherwin, Chris Stockmann, Kristin N Grimsrud, David Herd, Brian J. Anderson, Michael G. Spigarelli> ;Paediatric Anaesthesia. 2015 Feb 1
30 citations
Clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection
Chris Stockmann, Jessica K. Roberts, Elizabeth D. Knackstedt, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Expert Opinion on Drug Metabolism & Toxicology. 2015 Jan 14
26 citations
Levofloxacin inhalation solution for the treatment of chronic Pseudomonas aeruginosa infection among patients with cystic fibrosis
Chris Stockmann, Brad Hillyard, Krow Ampofo, Michael G. Spigarelli, Catherine M.T. Sherwin> ;Expert Review of Respiratory Medicine. 2015 Jan 13
2 citations
Nonsteroidal Anti-inflammatory Drug-associated Nephrotoxicity Among Neonate Diagnosed With Patent Ductus Arteriosus
Jonathan E. Constance, Robert M. Ward, Catherine M.T. Sherwin, E. Kent Korgenski, Michael G. Spigarelli> ;Clinical Pharmacology in Drug Development. 2015 Jan 1
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Press Mentions

BioSpace Movers & Shakers, April 9April 8th, 2021
PsyBio Strengthens Its Leadership Team with Appointment of Dr. Michael Spigarelli as Chief Medical OfficerApril 5th, 2021