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1 Medical Plaza DriveIrvine, CA 92697
Phone+1 949-824-8816
Fax+1 855-209-8413
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Summary
- Dr. Michael Sy is a neurologist in Irvine, CA and is an Assistant Professor with UC Irvine Health. He received his MD and PhD from University of California Irvine School of Medicine and has been in practice 6 years. He specializes and has experience in neuroimmunology/multiple sclerosis.
Education & Training
University of California (Irvine)Residency, Neurology, 2011 - 2014
University of California, Irvine, School of MedicineClass of 2011
Yale UniversityBS, Biology, 1998 - 2002- University of California (Irvine)Fellowship, Neuroimmunology & Multiple Sclerosis
Certifications & Licensure
CA State Medical License 2013 - 2028
American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Marilyn Hilton Innovator Award Hilton Foundation, 2017-2020
Clinical Trials
- A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS) Start of enrollment: 2021 Mar 17
- A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS) Start of enrollment: 2020 Dec 03
- Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Participants With Early Stage Relapsing Remitting Multiple Sclerosis (RRMS) Start of enrollment: 2017 Mar 24
Publications & Presentations
PubMed
- Acute effects of high-dose corticosteroids on serum biomarker profiles in primary CNS demyelinating disease: A pilot study.Anastasia P Chumakova, Michael Demetriou, Michael Sy
Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2026-09-07 - Autologous Stem Cell Transplantation for Multiple Sclerosis.Shreya Condamoor, Pongthep Vittayawacharin, Michael Sy, Piyanuch Kongtim, Stefan O Ciurea
Transplantation and Cellular Therapy. 2026-05-01 - Neurogenic Lower Urinary Tract Dysfunction in Women With Multiple Sclerosis.Kruti Patel, Amy Yan, Alejandra Cacheiro, Michael Sy, Michael Demetriou
Urogynecology. 2026-04-30
Press Mentions
Benefits of Medications for MS Outweigh Risks, Says UCI Health NeurologistAugust 6th, 2025
Depression, Constipation, and Urinary Tract Infections May Precede MS DiagnosisDecember 5th, 2023
Octave Bioscience Gaining Traction Among CliniciansNovember 6th, 2023
Grant Support
- Oral N-Acetylglucosamine as Anti-Neuroinflammatory Add-on therapy for Multiple Sclerosis (NANA-MS)UNIVERSITY OF CALIFORNIA-IRVINE2025–2026
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