MichaelPThomasMD

PubMed

• Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies.
  Hacken, E. T.,Valentin, R.,Regis, FFD.,Sun, J.,Yin, S.,Werner, L.,Deng, J.,Gruber, M.,Wong, J.,Zheng, M.,Gill, A. L.,Seiler, M.,Smith, P.,Thomas, M.,Buonamici, S.,Ghia...> ;JCI Insight. 2018 Oct 05
• H3B-8800, an Orally Available Small-Molecule Splicing Modulator, Induces Lethality in Spliceosome-Mutant Cancers
  Michael Thomas, Virginia Klimek, Eric Padron, John Wang, Omar Abdel-Wahab> ;Nature. 2018 Feb 20
• Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial.
  Kim, D. W.,Mehra, R.,Tan, D. S.,Felip, E.,Chow, L. Q.,Camidge, D. R.,Vansteenkiste, J.,Sharma, S.,De Pas, T.,Riely, G. J.,Solomon, B. J.,Wolf, J.,Thomas, M.,Schuler, M...> ;Lancet Oncol.. 1900 Jan 01
• Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation.
  Popat U, Mehta RS, Rezvani K, Fox P, Kondo K, Marin D, McNiece I, Oran B, Hosing C, Olson A, Parmar S, Shah N, Andreeff M, Kebriaei P, Kaur I, Yvon E, de Lima M, Coope...> ;Blood. 2015-05-07
• 14 citations
  Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids.
  Scott F. Allen, Robert W. Godley, Joshua M. Evron, Amer Heider, John M. Nicklas, Michael P. Thomas> ;The Canadian Journal of Cardiology. 2014 Dec 1
• Cor Triatriatum: A Reversible Cause of Severe Pulmonary Hypertension.
  Howe, M. J.,Thomas, M. P.,Agarwal, P. P.,Bach, D. S.,Rubenfire, M.> ;Can J Cardiol. 2015 Mar 10
• Nedd8-Activating Enzyme Inhibitor MLN4924 Provides Synergy with Mitomycin C through Interactions with ATR, BRCA1/BRCA2, and Chromatin Dynamics Pathways.
  Garcia, K.,Blank, J. L.,Bouck, D. C.,Liu, X. J.,Sappal, D. S.,Hather, G.,Cosmopoulos, K.,Thomas, M. P.,Kuranda, M.,Pickard, M. D.,Liu, R.,Bandi, S.,Smith, P. G.,Lightc...> ;Mol. Cancer Ther.. 2014 Mar 29
• Ceritinib in ALK-rearranged non-small-cell lung cancer.
  Shaw, A. T.,Kim, D. W.,Mehra, R.,Tan, D. S.,Felip, E.,Chow, L. Q.,Camidge, D. R.,Vansteenkiste, J.,Sharma, S.,De Pas, T.,Riely, G. J.,Solomon, B. J.,Wolf, J.,Thomas, M...> ;N. Engl. J. Med.. 2014 Mar 29
• When is it right to be wrong?
  Thomas, M. P.,Gurm, H. S.,Nallamothu, B. K.> ;J. Am. Coll. Cardiol.. 2013 Nov 05
• Absolute Quantification of E1, Ubiquitin-Like Proteins and Nedd8-MLN4924 Adduct by Mass Spectrometry.
  Yang, X.,Brownell, J. E.,Xu, Q.,Zhu, F.,Ma, J.,Loke, H. K.,Rollins, N.,Soucy, T. A.,Minissale, J. J.,Thomas, M. P.,Mallender, W. D.,Dick, L. R.,Li, P.,Liao, H.> ;Cell Biochem. Biophys.. 2013 Sep
• Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer.
  Nawrocki, S. T.,Kelly, K. R.,Smith, P. G.,Espitia, C. M.,Possemato, A.,Beausoleil, S. A.,Milhollen, M.,Blakemore, S.,Thomas, M.,Berger, A.,Carew, J. S.> ;Clin. Cancer Res.. 2013 Jul 1
• Balancing the yin and the yang of vascular closure.
  Thomas, M. P.,Gurm, H. S.> ;J Invasive Cardiol. 2012 Mar 06
• Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML.
  Deisseroth AB, Zu Z, Claxton D, Hanania EG, Fu S, Ellerson D, Goldberg L, Thomas M, Janicek K, Anderson WF> ;Blood. 1994-05-15
• Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis.
  Hull R, Hirsh J, Jay R, Carter C, England C, Gent M, Turpie AG, McLoughlin D, Dodd P, Thomas M, Raskob G, Ockelford P> ;N. Engl. J. Med.. 1982-12-30
• Hepatitis A vaccination.
  Thomas, M. P.> ;N Engl J Med. 1998 Sep 3
• The secret to achieving reliable biological phosphorus removal.
  Thomas, M. P.> ;Water Sci Technol. 2008 Oct 11
• Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
  Mawji, I. A., Simpson, C. D., Hurren, R., Gronda, M., Williams, M. A., Filmus, J., Jonkman, J., Da Costa, R. S., Wilson, B. C., Thomas, M. P., Reed, J. C., Glinsky, G....> ;J Natl Cancer Inst. 2007 May 16
• Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors.
  Schimmer, A. D., Thomas, M. P., Hurren, R., Gronda, M., Pellecchia, M., Pond, G. R., Konopleva, M., Gurfinkel, D., Mawji, I. A., Brown, E., Reed, J. C.> ;Cancer Res. 2006 Feb 15
• Outcome of contemporary percutaneous coronary intervention in the elderly and the very elderly: insights from the Blue Cross Blue Shield of Michigan Cardiovascular Con...
  Thomas, M. P., Moscucci, M., Smith, D. E., Aronow, H., Share, D., Kraft, P., Gurm, H. S.> ;Clin Cardiol. 2011 Sep
• Evaluation of pathogen removal in a solar sludge drying facility using microbial indicators.
  Shanahan, E. F., Roiko, A., Tindale, N. W., Thomas, M. P., Walpole, R., Kurtböke, D. I.> ;Int J Environ Res Public Health. 2010 Feb
• MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma.
  Milhollen, M. A., Traore, T., Adams-Duffy, J., Thomas, M. P., Berger, A. J., Dang, L., Dick, L. R., Garnsey, J. J., Koenig, E., Langston, S. P., Manfredi, M., Narayana...> ;Blood. 2010 Sep 2
• An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
  Soucy, T. A., Smith, P. G., Milhollen, M. A., Berger, A. J., Gavin, J. M., Adhikari, S., Brownell, J. E., Burke, K. E., Cardin, D. P., Critchley, S., Cullis, C. A., Do...> ;Nature. 2009 Apr 09
• Clinical problem-solving. Taken out of context.
  Thomas, M. P., Wang, A.> ;N Engl J Med. 2008 Dec 04
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