MichalFilipTomczakMD

Gastroenterology • Needham, MA

Advanced Endoscopic Interventional, Inflammatory Bowel Disease

Gastroenterology Attending, Brigham and Women's Hospital

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Office
464 Hillside Ave
Suite 201
Needham, MA 02494
Phone+1 781-444-6460
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Education & Training

Brigham and Women's HospitalFellowship, Gastroenterology, 2008 - 2012
St Elizabeth's Medical CenterResidency, Internal Medicine, 2006 - 2008
University of Medical Science PoznanClass of 2000

Certifications & Licensure

MA State Medical License 2009 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Publications & Presentations

PubMed

45 citations
Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Jieru E. Lin, Francheska Colon-Gonzalez, Erik S. Blomain, Gilbert W. Kim, Amanda Aing, Brian Arthur Stoecker, Justin Rock, Adam E. Snook, Tingting Zhan, Terry Hyslop, ...> ;Cancer Research. 2016 Jan 15
133 citations
Efficacy of Vedolizumab as Induction Therapy in Refractory IBD Patients: A Multicenter Cohort.
Edward Shelton, Jessica R. Allegretti, Betsy W. Stevens, Matthew B. Lucci, Hamed Khalili, Deanna D. Nguyen, Jenny Sauk, Cosmas Giallourakis, John J. Garber, Matthew J....> ;Inflammatory Bowel Diseases. 2015 Dec 1
92 citations
Early-onset Crohn’s disease and autoimmunity associated with a variant in CTLA-4
Sebastian Zeissig, Britt-Sabina Petersen, Michal Tomczak, Espen Melum, Emilie Huc-Claustre, Stephanie K. Dougan, Jon K. Laerdahl, Bjoern Stade, Michael Forster, Stefan...> ;Gut. 2015 Dec 1
510 citations
Paneth cells as a site of origin for intestinal inflammation
Timon E. Adolph, Michal Tomczak, Lukas Niederreiter, Hyun-Jeong Ko, Janne Böck, Eduardo Martínez-Naves, Jonathan N. Glickman, Markus Tschurtschenthaler, John H. Hartwi...> ;Nature. 2013 Nov 14
107 citations
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
Lukas Niederreiter, Teresa M.J. Fritz, Timon E. Adolph, Anna-Maria Krismer, Felix Offner, Markus Tschurtschenthaler, Magdalena B. Flak, Shuhei Hosomi, Michal Tomczak, ...> ;The Journal of Experimental Medicine. 2013 Sep 23
41 citations
The unfolded protein response and its role in intestinal homeostasis and inflammation
Arthur Kaser, Magdalena B. Flak, Michal Tomczak, Richard S. Blumberg> ;Experimental Cell Research. 2011 Nov 15
31 citations
NF-κB1 Inhibits TLR-Induced IFN-β Production in Macrophages through TPL-2–Dependent ERK Activation
Huei-Ting Yang, Yan Yan Wang, Xixing Zhao, Ezana Demissie, Stamatia Papoutsopoulou, Agnes Mambole, Anne O'Garra, Michal Tomczak, Susan E. Erdman, James G. Fox, Steven ...> ;Journal of Immunology. 2011 Feb 15
11 citations
"ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine.
Arthur Kaser, Michal Tomczak, Richard S. Blumberg> ;Gastroenterology. 2011 Feb 1
33 citations
Inhibition of Helicobacter hepaticus-induced colitis by IL-10 requires the p50/p105 subunit of NF-kappa B.
Michal Tomczak, Susan E. Erdman, Anne Davidson, Yan Yan Wang, Prashant R. Nambiar, Arlin B. Rogers, Barry H. Rickman, David Luchetti, James G. Fox, Bruce H. Horwitz> ;Journal of Immunology. 2006 Nov 15
32 citations
Defective Activation of ERK in Macrophages Lacking the p50/p105 Subunit of NF-κB Is Responsible for Elevated Expression of IL-12 p40 Observed after Challenge with Heli...
Michal Tomczak, Mihaela Gadjeva, Yan Yan Wang, Ketorah Brown, Ioanna G. Maroulakou, Philip N. Tsichlis, Susan E. Erdman, James G. Fox, Bruce H. Horwitz> ;Journal of Immunology. 2006 Jan 15
62 citations
A Role for NF-κB Subunits p50 and p65 in the Inhibition of Lipopolysaccharide-Induced Shock
Mihaela Gadjeva, Michal Tomczak, Ming Zhang, Yan Yan Wang, Karen E. Dull, Arlin B. Rogers, Susan E. Erdman, James G. Fox, Michael C. Carroll, Bruce H. Horwitz> ;Journal of Immunology. 2004 Nov 1
488 citations
Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses.
Spencer C Liang, Yvette Latchman, Janet E. Buhlmann, Michal Tomczak, Bruce H. Horwitz, Gordon J. Freeman, Arlene H. Sharpe> ;European Journal of Immunology. 2003 Oct 1
168 citations
CD4(+)CD25(+) Regulatory Lymphocytes Require Interleukin 10 to Interrupt Colon Carcinogenesis in Mice
Susan E. Erdman, Varada P. Rao, Theofilos Poutahidis, Melanie Ihrig, Zhongming Ge, Yan Feng, Michal Tomczak, Arlin B. Rogers, Bruce H. Horwitz, James G. Fox> ;Cancer Research. 2003 Sep 15
49 citations
NF-κB Is Required Within the Innate Immune System to Inhibit Microflora-Induced Colitis and Expression of IL-12 p40
Michal Tomczak, Susan E. Erdman, Theofilos Poutahidis, Arlin B. Rogers, Hilda Holcombe, Benjamin Plank, James G. Fox, Bruce H. Horwitz> ;Journal of Immunology. 2003 Aug 1
241 citations
CD4+ CD25+ Regulatory T Lymphocytes Inhibit Microbially Induced Colon Cancer in Rag2-Deficient Mice
Susan E. Erdman, Theofilos Poutahidis, Michal Tomczak, Arlin B. Rogers, Kathleen S. Cormier, Benjamin Plank, Bruce H. Horwitz, James G. Fox> ;The American Journal of Pathology. 2003 Feb 1
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Hospital Affiliations

Newton-Wellesley HospitalNewton Lower Falls, Massachusetts
Beth Israel Deaconess Hospital-NeedhamNeedham, Massachusetts