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Michelle Baack, MD, Neonat/Perinatology, Sioux Falls, SD, Sanford USD Medical Center

MichelleL.BaackMD(She/Her)

Neonat/Perinatology Sioux Falls, SD

Associate Professor and Chair of Pediatrics, The University of South Dakota - Sanford School of Medicine Associate Scientist, Environmental Influences on Health and Disease Group, Sanford Research

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Summary

  • Dr. Baack completed her undergraduate training at South Dakota State University (SDSU) College of Pharmacy, Medical School at the University of South Dakota – Sanford School of Medicine and Pediatric Residency at Creighton - University of Nebraska Joint Pediatric Residency Program in Omaha. She practiced as a general pediatrician for 10 years in Pierre, SD before returning to a fellowship in Neonatal and Perinatal Medicine at the University of Iowa where she developed a passion for perinatal and neonatal research. She is currently a neonatologist in the Boekelheide Neonatal Intensive Care Unit at Sanford Children’s Hospital, an Associate Professor and the Chair of Pediatrics at the University of South Dakota – Sanford School of Medicine and an Associate Scientist in the Environmental Influences on Health and Disease Group at Sanford Research. Her primary research objective is to understand the role of maternal and neonatal lipid abnormalities in the developmental origin of health and disease (DOHaD) and to develop preventative strategies to decrease the risk of both short and long-term disease in high-risk populations including infants born to obese or diabetic mothers. To meet this objective, she has both clinical and basic science platforms. As the Sanford – site principal investigator for NICHD Neonatal Research Networks (NRN), her clinical research works to improve the outcomes of premature infants. Basic and translational research in the Baack lab focuses on understanding the mitochondria-mediated mechanisms of developmental programming of heart disease in a fetus exposed to maternal dyslipidemia or diabetic pregnancy. Her overarching goal is to find translational dietary interventions that improve mitochondrial function, metabolism and prevent cardiovascular disease in not only one, but subsequent generations.

Education & Training

  • University of Iowa Hospitals and Clinics
    University of Iowa Hospitals and ClinicsFellowship, Neonatal-Perinatal Medicine, 2008 - 2011
  • University of Nebraska Medical Center College of Medicine
    University of Nebraska Medical Center College of MedicineResidency, Pediatrics, 1996 - 1999
  • University of South Dakota, Sanford School of Medicine
    University of South Dakota, Sanford School of MedicineClass of 1995

Certifications & Licensure

  • SD State Medical License
    SD State Medical License Active through 2025
  • IA State Medical License
    IA State Medical License 2008 - 2018
  • MN State Medical License
    MN State Medical License 2012 - 2016
  • American Board of Pediatrics Neonatal-Perinatal Medicine

Clinical Trials

Publications & Presentations

PubMed

Grant Support

  • Dietary interventions to modulate heart health in offspring born to diabetic mothers and the subsequent generationNIH/NHLBI2022–Present
  • NICHD Cooperative Multicenter Neonatal Research NetworkNIH-NICHD2017–Present
  • Mitochondria, metabolic plasticity and cell fate in the developmental origin of fuel-mediated cardiomyopathyNIH/NIGMS2018–2022
  • Extracellular matrix to optimize cardiomyogenesis from mesenchymal stem cells for applications in cardiovascular regenerative medicine.Sanford Foundation Research Fund2018–2020
  • Is the heterogenic mother mitochondrial DNA genome a cause of rejection in transplanted organs from cloned animals?T. Denny Pediatric Collaborative Pilot Project2017–2019
  • Lipotoxic Effects of Maternal Diabetes and High Fat Diet on the Developing HeartNIH/NICHD2014–2019
  • Epigenetic Outcome of Prenatal High-fat Diet in Offspring Cardiometabolic HealthSanford Health-SDSU Collaborative Research Seed Grant2014–2015
  • Maternal diabetes or high-fat intake alters lipid fuel stores in the developing fetal heartUSD-SSOM Faculty Development Grant2014–2015
  • Bridging the Docosahexeanoic Acid (DHA) Gap of Prematurity: The Effects of Omega-3 Fatty Acid Supplementation in Premature BabiesGerber Foundation2012–2015
  • Overcoming the DHA Deficit in Premature Infants through Daily SupplementationSanford Health Seed Grant2012–2013
  • Cardiovascular Effects of Late Gestation Hyperglycemia and High Fat Diet in Offspring: Are Lipids the Culprit?Sanford Burnham Collaborative Research Fund2011–2012
  • The Modulation of Diabetic Embryopathy by Long Chain Polyunsaturated Fatty AcidsChildren's Miracle Network2010–2011
  • Long Chain Polyunsaturated Fatty Acids in Donor Human Milk: Enough for a Lifetime of Benefit?NIH/T322009–2010

Hospital Affiliations