MichelleChristineCrankMD

PubMed

• 12 citations
  An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults.
  Alicia T Widge, Amelia R Hofstetter, Katherine V Houser, Seemal F Awan, Grace L Chen, Maria C Burgos Florez, Nina M Berkowitz, Floreliz Mendoza, Cynthia S Hendel, LaSo...> ;Science Translational Medicine. 2023 Apr 19
• 12 citations
  A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine.
  Lauren A Chang, Emily Phung, Michelle C Crank, Kaitlyn M Morabito, Tonya Villafana, Filip Dubovsky, Judith Falloon, Mark T Esser, Bob C Lin, Grace L Chen, Barney S Gra...> ;Science Translational Medicine. 2022 Dec 21
• 12 citations
  Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
  Syed M Moin, Jeffrey C Boyington, Seyhan Boyoglu-Barnum, Rebecca A Gillespie, Gabriele Cerutti, Crystal Sao-Fong Cheung, Alberto Cagigi, John R Gallagher, Joshua Brand...> ;Immunity. 2022 Dec 13
• 7 citations
  CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines.
  Sean A Nelson, Katherine A Richards, Maryah A Glover, Francisco A Chaves, Michelle C Crank, Barney S Graham, Masaru Kanekiyo, Andrea J Sant> ;NPJ Vaccines. 2022 Oct 26
• 7 citations
  Elicitation of pneumovirus-specific B cell responses by a prefusion-stabilized respiratory syncytial virus F subunit vaccine.
  Emily Phung, Lauren A Chang, Maryam Mukhamedova, Lijuan Yang, Deepika Nair, Scott A Rush, Kaitlyn M Morabito, Jason S McLellan, Ursula J Buchholz, John R Mascola, Mich...> ;Science Translational Medicine. 2022 Jun 22
• 54 citations
  Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial.
  Katherine V Houser, Grace L Chen, Cristina Carter, Michelle C Crank, Thuy A Nguyen, Maria Claudia Burgos Florez, Nina M Berkowitz, Floreliz Mendoza, Cynthia Starr Hend...> ;Nature Medicine. 2022 Feb 1
• 31 citations
  Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation cli...
  Tracy J. Ruckwardt, Kaitlyn M. Morabito, Emily Phung, Michelle C. Crank, Pamela Costner, LaSonji A. Holman, Lauren A. Chang, Somia P. Hickman, Nina M. Berkowitz, Ingel...> ;The Lancet. Respiratory Medicine. 2021 Oct 1
• 25 citations
  Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
  Maryam Mukhamedova, Daniel Wrapp, Chen-Hsiang Shen, Morgan S.A. Gilman, Tracy J. Ruckwardt, Chaim A. Schramm, Larissa Ault, Lauren A. Chang, Alexandrine Derrien-Colemy...> ;Immunity. 2021 Apr 13
• 146 citations
  Quadrivalent influenza nanoparticle vaccines induce broad protection.
  Seyhan Boyoglu-Barnum, Daniel Ellis, Rebecca A. Gillespie, Geoffrey B. Hutchinson, Young-Jun Park, Syed M. Moin, Oliver J. Acton, Rashmi Ravichandran, Michael E. P. Mu...> ;Nature. 2021 Mar 24
• 30 citations
  A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies.
  Adrian Creanga, Rebecca A. Gillespie, Brian E. Fisher, Sarah F. Andrews, Julia Lederhofer, Christina Yap, Liam Hatch, Tyler Stephens, Yaroslav Tsybovsky, Michelle C. C...> ;Nature Communications. 2021 Mar 19
• 44 citations
  Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
  Nicole Darricarrère, Yu Qiu, Masaru Kanekiyo, Adrian Creanga, Rebecca A. Gillespie, Syed M. Moin, Jacqueline Saleh, Jose Sancho, Te Hui Chou, Yanfeng Zhou, Ruijun Zhan...> ;Science Translational Medicine. 2021 Mar 3
• 5 citations
  Author Correction: Next-generation influenza vaccines: opportunities and challenges
  Chih-Jen Wei, Michelle C. Crank, John Shiver, Barney S. Graham, John R. Mascola, Gary J. Nabel> ;Nature Reviews. Drug Discovery. 2020 Jun 1
• 163 citations
  Next-generation influenza vaccines: opportunities and challenges
  Chih-Jen Wei, Michelle C. Crank, John Shiver, Barney S. Graham, John R. Mascola, Gary J. Nabel> ;Nature Reviews. Drug Discovery. 2020 Feb 14
• 30 citations
  Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
  Seyhan Boyoglu-Barnum, Geoffrey B. Hutchinson, Jeffrey C. Boyington, Syed M. Moin, Rebecca A. Gillespie, Yaroslav Tsybovsky, Tyler Stephens, John R. Vaile, Julia Leder...> ;Nature Communications. 2020 Feb 7
• 83 citations
  Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin
  Sarah F. Andrews, Michael Chambers, Chaim A. Schramm, Jason Plyler, Julie E. Raab, Masaru Kanekiyo, Rebecca A. Gillespie, Amy Ransier, Sam Darko, Jianfei Hu, Xuejun Ch...> ;Immunity. 2019 Aug 20
• 182 citations
  A proof of concept for structure-based vaccine design targeting RSV in humans.
  Michelle C. Crank, Tracy J. Ruckwardt, Man Chen, Kaitlyn M. Morabito, Emily Phung, Pamela Costner, LaSonji A. Holman, Somia P. Hickman, Nina M. Berkowitz, Ingelise J. ...> ;Science. 2019 Aug 2
• 6 citations
  Preparing for the Next Influenza Pandemic: The Development of a Universal Influenza Vaccine.
  Michelle C. Crank, John R. Mascola, Barney S. Graham> ;The Journal of Infectious Diseases. 2019 Apr 8
• 74 citations
  Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages
  Kizzmekia S. Corbett, Syed M. Moin, Hadi M. Yassine, Alberto Cagigi, Masaru Kanekiyo, Seyhan Boyoglu-Barnum, Sky I Myers, Yaroslav Tsybovsky, Adam K. Wheatley, Chaim A...> ;Mbio. 2019 Feb 26
• 25 citations
  Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.
  Hadi M. Yassine, Patrick M. Mctamney, Jeffery C. Boyington, Tracy J. Ruckwardt, Michelle C. Crank, Maria K. Smatti, Julie E. Ledgerwood, Barney S. Graham> ;Scientific Reports. 2018 Jun 5
• 70 citations
  Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.
  Sarah F. Andrews, M. Gordon Joyce, Michael Chambers, Rebecca A. Gillespie, Masaru Kanekiyo, Kwanyee Leung, Eun Sung Yang, Yaroslav Tsybovsky, Adam K. Wheatley, Michell...> ;Science Immunology. 2017 Jul 14
• 21 citations
  An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial.
  Adam DeZure, Emily E. Coates, Zonghui Hu, Galina Yamshchikov, Kathryn L Zephir, Mary E. Enama, Sarah H. Plummer, Ingelise J. Gordon, Florence Kaltovich, Sarah F. Andre...> ;NPJ Vaccines. 2017 Jun 1
• 13 citations
  Safety and Immunogenicity of a rAd35-EnvA Prototype HIV-1 Vaccine in Combination with rAd5-EnvA in Healthy Adults (VRC 012).
  Michelle C. Crank, Eleanor Wilson, Laura Novik, Mary E. Enama, Cynthia S. Hendel, Wenjuan Gu, Martha Nason, Robert T. Bailer, Gary J. Nabel, Adrian B. McDermott, John ...> ;Plos One. 2016 Nov 15
• 19 citations
  IL-1β enhances inflammatory TH2 differentiation
  Stephan M. Caucheteux, Jane Hu-Li, Liying Guo, Nisan Bhattacharyya, Michelle C. Crank, Michael T. Collins, William E. Paul> ;The Journal of Allergy and Clinical Immunology. 2016 Sep 1
• 18 citations
  Phase 1 study of pandemic H1 DNA vaccine in healthy adults.
  Michelle C. Crank, Ingelise J. Gordon, Galina Yamshchikov, Sandra Sitar, Zonghui Hu, Mary E. Enama, LaSonji A. Holman, Robert T. Bailer, Melissa B. Pearce, Richard A. ...> ;Plos One. 2015 Apr 17
• 119 citations
  Mutations in PIK3CD can cause hyper IgM syndrome (HIGM) associated with increased cancer susceptibility.
  M. C. Crank, Jennifer Grossman, Susan Moir, Stefania Pittaluga, Clarisa M. Buckner, Lela Kardava, Anahita Agharahimi, H. Meuwissen, Jennifer Stoddard, Julie E. Niemela...> ;Journal of Clinical Immunology. 2014 Mar 8
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