Michelle A. Fanale MD

Oncology•Bothell, WA

Hematologic Oncology

Global Medical Strategy, CD30 Portfolio Lead (Brentuximab Vedotin, 35C, 35T)

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Pfizer2500 223rd St SEBothell, WA 98021
Phone+1 425-527-4000

Education & Training

University of Texas Health Science Center at Houston/M D Anderson Cancer CenterFellowship, Hematology and Medical Oncology, 2002 - 2005
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1999 - 2002
Rutgers New Jersey Medical SchoolClass of 1999
Rutgers College BA, Biochemistry/ Molecular Biology & Psychology , 1990 - 1994

Certifications & Licensure

TX State Medical License 2002 - 2022
AZ State Medical License 2001 - 2017
MN State Medical License 2000 - 2015

Clinical Trials

SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma Start of enrollment: 2006 Aug 01
Terminated
Phase 2
Velcade Plus ICE for Patients With Relapsed Classical Hodgkin Lymphoma Start of enrollment: 2007 Feb 01
Completed
Phase 1
Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma Start of enrollment: 2008 Mar 19
Completed
Phase 2
Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment. Start of enrollment: 2009 Aug 24
Completed
Phase 2
Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma Start of enrollment: 2011 Jun 21
Completed
Phase 1
Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma Start of enrollment: 2011 Nov 01
Active, not recruiting
Phase 2
ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas Start of enrollment: 2013 Jan 31
Completed
Phase 3
A Safety Study of SGN-CD19A for B-Cell Lymphoma Start of enrollment: 2013 Feb 01
Completed
Phase 1
Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas Start of enrollment: 2013 Jul 17
Completed
Phase 1
Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational) Start of enrollment: 2014 Aug 12
Completed
Phase 2
Nivolumab and Brentuximab Vedotin in Treating Older Patients With Untreated Hodgkin Lymphoma Start of enrollment: 2016 May 13
ACTIVE_NOT_RECRUITING
PHASE2
Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma Start of enrollment: 2017 Mar 08
ACTIVE_NOT_RECRUITING
PHASE1, PHASE2
Nivolumab, Ifosfamide, Carboplatin, and Etoposide as Second-Line Therapy in Treating Patients With Refractory or Relapsed HL Start of enrollment: 2017 Apr 24
ACTIVE_NOT_RECRUITING
PHASE2
Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma Start of enrollment: 2017 May 25
ACTIVE_NOT_RECRUITING
PHASE2
Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL. Start of enrollment: 2017 Jul 18
ACTIVE_NOT_RECRUITING
PHASE1
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Publications & Presentations

PubMed

14 citations
Brentuximab Vedotin Combination for Relapsed Diffuse Large B-Cell Lymphoma.
Nancy L Bartlett, Uwe Hahn, Won-Seog Kim, Isabelle Fleury, Kamel Laribi
Journal of Clinical Oncology. 2025-03-20
6 citations
Brentuximab vedotin, nivolumab, doxorubicin, and dacarbazine for advanced-stage classical Hodgkin lymphoma.
Hun Ju Lee, Rod Ramchandren, Judah Friedman, Jason Melear, Ian W Flinn
Blood. 2025-01-16
1 citations
A systematic literature review of clinical evidence and treatment burden in newly diagnosed high-risk pediatric patients with classical Hodgkin lymphoma.
Jamie E Flerlage, Christine Waters-Banker, Michelle Fanale, Rachel Beckerman, Sharon M Castellino
Pediatric Blood & Cancer. 2024-08-01

Journal Articles

Long‐Term Overall‐ and Progression‐Free Survival After Pentostatin, Cyclophosphamide and Rituximab Therapy for Indolent Non‐Hodgkin Lymphoma
Peter McLaughlin, M Alma Rodriguez, Sattva S Neelapu, Anas Younes, Lei Feng, Michelle A Fanale, Felipe Samaniego, Barbara Pro, Luis Fayad, Fredrick Hagemeister, Jorge ..., British Journal of Haematology
Rituximab with ABVD vs ABVD for Advanced Stage High-Risk Classical Hodgkin Lymphoma: A Randomized Phase II Study
Francesco Turturro, Luis E Fayad, Anas Younes, Michelle Fanale, Yasuhiro Oki, Hun Ju Lee, Nancy L Bartlett, Haematologica

Lectures

Safety and efficacy of anti-CD20 immunotoxin MT-3724 in relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (NHL) in a phase I study.
2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018

Press Mentions

My B-cell Lymphoma Treatment During PregnancyJune 21st, 2018
Novel Agents Show Impressive Activity in Hodgkin LymphomaOctober 27th, 2017
Longer Nivolumab Response Reported in Hodgkin Lymphoma PatientsAugust 10th, 2017
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