Michelle L Hernandez MD

Asthma & Allergic Conditions, Pediatric Asthma & Allergic Conditions

Professor of Pediatrics, Division of Allergy and Immunology, University of North Carolina-Chapel Hill School of Medicine. Director, Clinical Research Unit, UNC Children's Research Institute.

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2801 Blue Ridge Road, Ground FloorRaleigh, NC 27607
Phone+1 984-974-0500

Summary

I am a board certified pediatrician and allergist/immunologist. My clinical interests are focused on difficult-to-control asthma and other allergic disorders.

My research is focused on identifying pragmatic interventions to treat asthma, and the development of novel technology to enhance asthma care.

Education & Training

University of California (San Diego) Medical CenterFellowship, Allergy and Immunology, 2005 - 2007
University of North Carolina HospitalsResidency, Pediatrics, 2002 - 2005
University of North Carolina at Chapel Hill School of MedicineClass of 2002

Certifications & Licensure

NC State Medical License 2002 - 2026
CA State Medical License 2005 - 2007
American Board of Allergy and Immunology Allergy & Immunology

Clinical Trials

Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults Start of enrollment: 2008 May 01
Completed
Phase 1
Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers Start of enrollment: 2005 Oct 01
Completed
Phase 1
In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics
COMPLETED
PHASE1
Evaluation of Allergenicity of Hypoallergenic Peanut Product in Peanut Allergic Subjects Start of enrollment: 2011 Dec 01
Completed
Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2 Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Sulforaphane Supplementation in Atopic Asthmatics Start of enrollment: 2013 Apr 01
Completed
Phase 1
Observational Assessment of Baseline Asthma Control in African-American Children Start of enrollment: 2013 Jul 01
Completed
Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy Start of enrollment: 2015 Mar 03
Completed
Phase 1, Phase 2
To Determine the Measurement Properties of the ACT in an African American Adolescent Population With Persistent Asthma Start of enrollment: 2014 Oct 01
Completed
Screening Inhaled Allergen Challenge for Dermatophagoides Farinae Start of enrollment: 2018 Jan 29
Terminated
Early Phase 1
Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Start of enrollment: 2020 Sep 01
Withdrawn
Phase 1, Phase 2
Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Start of enrollment: 2019 Aug 09
Withdrawn
Phase 1, Phase 2
Woodsmoke Particulate + Hypertonic Saline Start of enrollment: 2019 Aug 01
COMPLETED
NA
Woodsmoke Particulate + Prednisone Start of enrollment: 2019 Mar 22
COMPLETED
PHASE1, PHASE2
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Publications & Presentations

PubMed

Evaluating the Impact of the COVID-19 Pandemic on Pediatric Asthma Incidence.
Ashley L Devonshire, Theresa Guilbert, Cindy S Bauer, Heidi Schmidt, Stephanie Davis
The Journal of Allergy and Clinical Immunology. in Practice. 2025-08-01
Meaningful Score Differences and Meaningful Score Regions of the Patient-Reported Outcomes Measurement Information System® Pediatric Asthma Impact Scale.
Jing Yuan, Li Lin, Kevin Weinfurt, Nicole Lucas, Allison J Burbank
Value in Health. 2025-06-05
3 citations
An Overview of Climate Changes and Its Effects on Health: From Mechanisms to One Health.
Ioana Agache, Michelle L Hernandez, Jared M Radbel, Harald Renz, Cezmi A Akdis
The Journal of Allergy and Clinical Immunology. in Practice. 2025-02-01

Journal Articles

Review and Feature Article Eosinophilic Granulomatosis with Polyangiitis: Clinical Pathology Conference and Review
Ronald J Falk, Eveline Y Wu, Michelle L Hernandez, ScienceDirect

Press Mentions

Novel Immunologic Surveillance Study Provides New Insights into Post-Pandemic Return of Respiratory VirusesAugust 6th, 2025
Newsworthy from the School of Medicine, Week of August 16 – August 22August 21st, 2024
UNC School of Medicine Experts to Present New Research at AAAAI and SRNT Annual Meetings in San FranciscoFebruary 19th, 2019
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