MiguelAngelPappollaMDPhD(He/Him)

PubMed

• Viral Infections, Are They a Trigger and Risk Factor of Alzheimer's Disease?
  Meagan D Rippee-Brooks, Wenzhe Wu, Xiaoyong Bao, Jianli Dong, Miguel Pappolla, Xiang Fang> ;Pathogens. 2024 Mar 8
• Changes of tRNA-Derived Fragments by Alzheimer's Disease in Cerebrospinal Fluid and Blood Serum.
  Wenzhe Wu, Audrey Shen, Inhan Lee, Ernesto G Miranda-Morales, Heidi Spratt, Miguel A Pappolla, Xiang Fang, Xiaoyong Bao> ;Journal of Alzheimer's Disease. 2023 Jan 1
• Nitric Oxide as a Determinant of Human Longevity and Health Span.
  Burkhard Poeggeler, Sandeep Kumar Singh, Kumar Sambamurti, Miguel A Pappolla> ;International Journal of Molecular Sciences. 2023 Sep 26
• 1 citations
  The Lymphatic System in Neurological Disease and Alzheimer's Disease. A Brief Editorial.
  Miguel A Pappolla, Roxana O Carare, Burkhand Poeggeler, Thomas Wisniewski, Kumar Sambamurti> ;Current Alzheimer Research. 2022 Jan 1
• 4 citations
  Tryptophan in Nutrition and Health.
  Burkhard Poeggeler, Sandeep Kumar Singh, Miguel A Pappolla> ;International Journal of Molecular Sciences. 2022 May 13
• 33 citations
  Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease
  Miguel A. Pappolla, George Perry, Xiang Fang, Michael G. Zagorski, Kumar Sambamurti, Burkhard Poeggeler> ;Neurobiology of Disease. 2021 Jun 1
• 6 citations
  Insulin Resistance is Associated with Central Pain in Patients with Fibromyalgia.
  Miguel A. Pappolla, Laxmaiah Manchikanti, Kenneth D. Candido, Nigel H. Grieg, Michael A. Seffinger, Fauwad Ahmed, Xiang Fang, Clark R. Andersen, Andrea M. Trescot> ;Pain Physician. 2021 Mar 1
• 2 citations
  HIV-Related Neuropathy: Pathophysiology, Treatment and Challenges
  Noushin Jazebi, Chad Evans, Hima S. Kadaru, Divya Kompella, Felix Fang, Mukaila Raji, Miguel A. Pappolla, Shao-Jun Tang, Jin Mo Chung, Bruce Hammock, Xiang Fang> ;Journal of Neurology and Experimental Neuroscience. 2021 Jan 1
• 17 citations
  Methodology for Evidence Synthesis and Development of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain.
  Laxmaiah Manchikanti, Sairam Atluri, Mark V. Boswell, Aaron K. Calodney, Sudhir Diwan, Sanjeeva Gupta, Alan D. Kaye, Nebojsa Nick Knezevic, Kenneth D. Candido, Alaa Ab...> ;Pain Physician. 2021 Jan 1
• 7 citations
  Methodology for Evidence Synthesis and Development of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain.
  Laxmaiah Manchikanti, Sairam Atluri, Mark V. Boswell, Aaron K. Calodney, Sudhir Diwan, Sanjeeva Gupta, Alan D. Kaye, Nebojsa Nick Knezevic, Kenneth D. Candido, Alaa Ab...> ;Pain Physician. 2021 Jan 1
• 5 citations
  Is insulin resistance the cause of fibromyalgia? A preliminary report.
  Miguel A. Pappolla, Laxmaiah Manchikanti, Clark R. Andersen, Nigel H. Greig, Fawad Ahmed, Xiang Fang, Michael A. Seffinger, Andrea M. Trescot> ;Plos One. 2019 May 6
• 58 citations
  Responsible, Safe, and Effective Use of Biologics in the Management of Low Back Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.
  Annu Navani, Laxmaiah Manchikanti, Sheri L. Albers, Richard E. Latchaw, Jaya Sanapati, Alan D. Kaye, Sairam Atluri, Sheldon E. Jordan, Ashim Gupta, David L. Cedeño, Al...> ;Pain Physician. 2019 Jan 1
• 67 citations
  Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis.
  Jaya Sanapati, Laxmaiah Manchikanti, Sairam Atluri, Sheldon E. Jordan, Sheri L. Albers, Miguel A. Pappolla, Alan D. Kaye, Kenneth D. Candido, Vidyasagar Pampati, Joshu...> ;Pain Physician. 2018 Nov 1
• 32 citations
  Melatonin treatment enhances Aβ lymphatic clearance in a transgenic mouse model of amyloidosis
  Miguel A. Pappolla, Etsuro Matsubara, Ruben Vidal, Javier Pacheco-Quinto, Burkhard Poeggeler, Michael G. Zagorski, Kumar Sambamurti> ;Current Alzheimer Research. 2018 May 31
• 213 citations
  Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer's Disease
  Robert J. Baranello, Krishna L. Bharani, Vasudevaraju Padmaraju, Nipun Chopra, Debomoy K. Lahiri, Nigel H. Greig, Miguel A. Pappolla, Kumar Sambamurti> ;Current Alzheimer Research. 2015 Jan 1
• 39 citations
  Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice
  Miguel A. Pappolla, Kumar Sambamurti, Ruben Vidal, Javier Pacheco-Quinto, Burkhard Poeggeler, Etsuro Matsubara> ;Neurobiology of Disease. 2014 Nov 1
• 16 citations
  Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.
  Eliza Barnwell, Vasudevaraju Padmaraju, Robert J. Baranello, Javier Pacheco-Quinto, Craig E. Crosson, Zsolt Ablonczy, Elizabeth A. Eckman, Christopher B. Eckman, Viswa...> ;Plos One. 2014 Mar 21
• 12 citations
  Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long.
  Inga Pinnix, Jorge Ghiso, Miguel A. Pappolla, Kumar Sambamurti> ;The American Journal of Geriatric Psychiatry. 2013 May 1
• 52 citations
  Targets for AD treatment: conflicting messages from γ-secretase inhibitors
  Kumar Sambamurti, Nigel H. Greig, Tadanobu Utsuki, Eliza Barnwell, Ekta Sharma, Cheryl Mazell, Narayan R. Bhat, Mark S. Kindy, Debomoy K. Lahiri, Miguel A. Pappolla> ;Journal of Neurochemistry. 2011 May 1
• 17 citations
  Amphiphilic amide nitrones: a new class of protective agents acting as modifiers of mitochondrial metabolism.
  Grégory Durand, Burkhard Poeggeler, Stéphanie Ortial, Ange Polidori, Frederick A. Villamena, Jutta Böker, Rüdiger Hardeland, Miguel A. Pappolla, Bernard Pucci> ;Journal of Medicinal Chemistry. 2010 Jul 8
• 31 citations
  A Novel Endogenous Indole Protects Rodent Mitochondria and Extends Rotifer Lifespan
  Burkhard Poeggeler, Kumar Sambamurti, Sandra L. Siedlak, George Perry, Mark A. Smith, Miguel A. Pappolla> ;Plos One. 2010 Apr 21
• 94 citations
  Higher incidence of mild cognitive impairment in familial hypercholesterolemia
  Daniel Zambón, Melibea Quintana, Pedro Mata, Rodrigo Alonso, Jaume Benavent, Félix F. Cruz-Sánchez, Jordi Gich, Miguel Pocovi, Fernando Civeira, Sebastian Capurro, Dav...> ;The American Journal of Medicine. 2010 Mar 1
• 65 citations
  Leptin and the skin: a new frontier
  Burkhard Poeggeler, Carla Schulz, Miguel A. Pappolla, Enikő Bodó, Stephan Tiede, Hendrik Lehnert, Ralf Paus> ;Experimental Dermatology. 2010 Jan 1
• 48 citations
  Differential Accumulation of Secreted AβPP Metabolites in Ocular Fluids
  Annamalai Prakasam, Anusuya Muthuswamy, Zsolt Ablonczy, Nigel H. Greig, Abdul H. Fauq, Kosagisharaf Jagannatha Rao, Miguel A. Pappolla, Kumar Sambamurti> ;Journal of Alzheimer's Disease. 2010 Jan 1
• 59 citations
  Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.
  Sandra L. Siedlak, Gemma Casadesus, Kate M. Webber, Miguel A. Pappolla, Craig S. Atwood, Mark A. Smith, George Perry> ;Free Radical Research. 2009 Jul 7
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Journal Articles

• Targets for AD treatment: conflicting messages from Gamma-secretase inhibitors.  
  Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA, J Neurochem, 5/1/2011
• Amphiphilic amide nitrones: a new class of protective agents acting as modifiers of mitochondrial metabolism.  
  J Med Chem, 7/1/2010
• Differential Accumulation of Secreted AbetaPP Metabolites in Ocular Fluids.  
  Prakasam A, Muthuswamy A, Ablonczy Z, Greig NH, Fauq A, Rao KJ, Pappolla MA, Sambamurti K, J Alzheimers Dis, 4/22/2010
• A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan.  
  Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA, PLoS One, 4/21/2010
• Higher Incidence of Mild Cognitive Impairment in Familial Hypercholesterolemia.  
  Am J Med, 3/1/2010
• Leptin and the skin: a new frontier.  
  Exp Dermatol, 1/1/2010
• Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.  
  Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G, Free Radic Res, 2/1/2009
• Frontiers in the pathogenesis of Alzheimer's disease. (Invited Article)  
  Sambamurti, K., Rao, K. J. and Pappolla, M. A., Indian Journal of Psychiatry, 1/1/2009
• Statins, incident Alzheimer disease, change in cognitive function, and neuropathology.  
  Pappolla MA, Neurology, 12/1/2008
• Value in development of a TAPIR-like mouse monoclonal antibody to Abeta.  
  Sambamurti K, Pappolla MA, Jagannatha Rao KS, J Alzheimers Dis., 6/1/2008
• Beta-secretase: structure, function, and evolution. (Review)  
  Venugopal C, Demos CM, Rao KS, Pappolla MA, Sambamurti K, CNS Neurol Disord Drug Targets, 6/1/2008
• Fine-Tuning the Amphiphilicity: A Crucial Parameter in the Design of Potent alpha-Phenyl-N-tert-butylnitrone Analogues.  
  Durand G, Poeggeler B, Boker J, Raynal S, Polidori A, Pappolla MA, Hardeland R, Pucci B, J Med Chem, 1/1/2007
• A unique case of limb-girdle muscular dystrophy type 2A carrying novel compound heterozygous mutations in the human CAPN3 gene.  
  Matsubara E, Tsuchiya A, Minami N, Nishino I, Pappolla MA, Shoji M, Abe K, Eur J Neurol., 1/1/2007
• Insulysin cleaves the APP cytoplasmic fragment at multiple sites.  
  Venugopal C, Pappolla MA, Sambamurti K, Neurochem Res., 1/1/2007
• Fluorinated amphiphilic amino acid derivatives as antioxidant carriers: a new class of protective agents.  
  Ortial S, Durand G, Poeggeler B, Polidori A, Pappolla MA, Boker J, Hardeland R, Pucci B, J Med Chem, 5/1/2006
• Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice.  
  Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA., Biochim Biophys Acta., 4/1/2006
• Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels.  
  Pacheco-Quinto J, Rodriguez de Turco EB, Derosa S, Howard A, Cruz-Sanchez F, Sambamurti K, Refolo L, Petanceska S, Pappolla MA, Neurobiol Dis., 1/1/2006
• Mitochondrial medicine: neuroprotection and life extension by the newamphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent.  
  Poeggeler B, Durand G, Polidori A, Pappolla MA, Vega-Naredo I, Coto-Montes A, Boker J, Hardeland R, Pucci B, J Neurochem., 11/1/2005
• Alzheimer's disease-a dysfunction in cholesterol and lipid metabolism.  
  Lukiw WJ, Pappolla M, Pelaez RP, Bazan NG, Cell Mol Neurobiol., 6/1/2005
• Melatonin Relieves the Neural Oxidative Burden that Contributes to Dementias.  
  Reiter RJ, Tan DX, Pappolla MA, Ann N Y Acad Sci., 12/1/2004
• Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.  
  Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, Herbert D, Cruz-Sanchez F, Chyan YJ, Smith MA, Perry G, Shoji M, Abe K, Leone A, Grun..., J Neurochem, 1/1/2003
• Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging.  
  Y.Z. Wadghiri, E.M. Sigurdsson, M. Sadowski , J.L.Elliott ,Y. Li , H. Scholtzova , C.Y. Tang , G. Aguinaldo , M. Pappolla, K. Duff , T. Wisniewski ,D.H. Turnbull, Magn Reson Med., 1/1/2003
• Hypercholesterolemia is an Early Risk Factor for the Development of Alzheimer Amyloid Pathology.  
  Pappolla MA, Bryant-Thomas TK, Herbert D, Pacheco J, Fabra Garcia M, Manjon M, Girones X, Henry TL, Matsubara E, Zambon D, Wolozin B, Petanceska SS, Sano M,..., Neurology, 1/1/2003
• Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol.  
  Petanceska SS, DeRosa S, Sharma A, Diaz N, Duff K, Tint SG, Refolo LM, Pappolla M, J Mol Neurosci, 1/1/2003
• Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP).  
  Marlow L, Cain M, Pappolla MA, Sambamurti K, J Mol Neurosci, 1/1/2003
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Books/Book Chapters

• Neuropathologia Diagnostico Y Clinica 
  Chapter: Molecular Biology and Neuropathology of Alzheimer's Disease. 
  Pappolla MAEditors: F. Cruz-Sanchez.Edimsa2000
• Free Radicals in Brain Pathophysiology. 
  Chapter: The role of Transgenic models for the Study of Oxidative Neurotoxicity in Alzheimer’s Disease. 
  M. A. Pappolla, Y-J Chyan, G. Perry, M.A. SmithEditors: Poli G and Cadenas E..2000
• Alzheimer’s Disease: Biology, Diagnosis and Therapeutics 
  Chapter: Dual Anti-amyloidogenic and Anti-oxidant Properties of Melatonin. A New Therapy for Alzheimer’s Disease? 
  Page 661 - 669Pappolla MA, Bozner P, Soto C, Shao H, Brewer G. Robakis NK, Zagorski M, Frangione B, Ghiso JEditors: K. Iqbal, B. Winblad, and H.M. Wisniewski.John Wiley & Sons Ltd.1999
• Handbook of Neurochemistry and Molecular Neurobiology 
  Chapter: Amyloid and Neurodegeneration: Alzheimer’s disease and retinal degeneration. 
  Prakasam, A., Venugopal, C., Suram, A., Pacheco-Quinto, J., Pappolla, M.A., Sharpe, K.A., Lahiri, D.K., Greig, N.H., Rohrer, B., Sambamurti, KEditors: Editor-in-chief: Lajtha, Abel, Volume Editors Banik, N and Ray, S.K..Edition 3rd ,1999
• Alzheimer’s Disease: Biology, Diagnosis and Therapeutics 
  Chapter: Oxidative Damage and Cell Death Induced by an Amyloid Peptide Fragment is Completely Prevented by Melatonin. 
  Page 741 - 749Pappolla MA, Sos M, Bick RJ, Omar RA, Hickson-Bick DLM, Reiter RJ, Efthimiopoulos S, Sambamurti K, Robakis NKEditors: K. Iqbal, B. Winblad, T. Nisimura, M. Takeda and H.M. Wisniewski.John Wiley & Sons Ltd.1997
• Perspectives on Behavioral Medicine 
  Chapter: Neuropathology and Molecular Biology of Alzheimer's Disease. 
  Pappolla MA, Robakis NKEditors: Stein M, Baum A.Lawrence Erlbaum Associates Publishers, New Jersey1995
• Ann New York Acad Sci.: Proteases and Protease Inhibitors in Alzheimer's Disease Pathogenesis. 
  Chapter: The Alzheimer's Amyloid Precursor is Cleaved Intracellularly in the Tran-Golgi Network or in a Post-Golgi Compartment. 
  Page 118 - 128Sambamurti K, Refolo LM, Shioi J, Pappolla MA, Robakis NKEditors: Banner, C.D.B. and Nixon, R.A..1992
• Healing Back And Joint Injuries: A Proven Approach To Ending Chronic Pain And Avoiding Unnecessary Surgery (Hardcover) 
  Joseph Valdez (Author), Miguel Pappolla (Co-author
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Abstracts/Posters

• Cognitive Impairment in Familial Heterozygous Hypercholesterolemia.
  Pappolla MA, Sambamurti K, Pacheco J, et al, World Congress of Alzheimer’s Congress, Chicago, IL., 7/1/2008
• Isoprenoids Phenocopy Familial AD Mutations And Regulate Gamma Secretase.
  Sambamurti K, Parkasam A, Venugopal, C, Jayachandran AD, Rao KS, Lahiri DK, Greig NH, Pappolla MA, Zhou Y, The Alzheimer's Association International Conference on Alzheimer's Disease (ICAD) McCormick Place, , 1/1/2008
• Alzheimer's Amyloid Protein Precursor and Neurotrophins in Age Related Retinal Degeneration.
  Sambamurti K, Pappolla MA, Granholm A-C, A. Prakasam A, Annual ARVO meeting, FT. Lauderdale, FL., 1/1/2008
• Changes in the Alzheimer’s Amyloid Protein Precursor Metabolism During Light-Induced Retinal Degeneration.
  Prakasam A, Pappolla MA, Rohrer B, Sambamurti K, Annual ARVO meeting, FT. Lauderdale, FL., 1/1/2008
• Protein misprocessing in Neurodegeneration.
  Sambamurti K, Venugopal C, Greig N, Pappolla M, Rohrer B, Prakasam A, Silver Jubilee Conference of Indian Academy of Neurosciences, Varanasi, India., 12/1/2007
• Amyloid Precursor Protein Metabolism in Retinal Degeneration.
  Sambamurti K, Venugopal C, Suram A, Pappolla M, Rohrer B, Annamalai P, Annual ARVO meeting, FT. Lauderdale, FL., 1/1/2007
• Common mechanism of neurodegeneration: role of Alzheimer's APP in light-induced retinal degeneration.
  Venugopal C, Haugabook S, Canet-Aviles R, Suram A, Pappolla M, Sambamurti K, 37th annual meeting of the Society for Neuroscience., 1/1/2007
• Cholesterol metabolism: A risk factor and potential therapeutic target for Alzheimer’s disease. Abstract # 551
  Refolo, L, Petanceska, S, DeRosa, S, Diaz, N, Bryant-Thomas, T, Sharma, A, Manjon, M, Cruz-Sanchez, F, Pappolla, M, 8th International Conference on Alzheimer’s Disease and Related Disorders., 1/1/2002
• In vivo detection of Alzheimer's amyloid by magnetic resonance imaging. Abstract # 1307
  Sigurdsson, EM, Wadghiri, YZ, Li, Q, Tang, CY, Aguilnaldo, JG, Duff, K, Pappolla, M, Elliott, JI, Watanabe, M, Scholtzova, H, Turnbull, DH, Wisniewski, T, 8th International Conference on Alzheimer’s Disease and Related Disorders, 1/1/2002
• Detection of Alzheimer’s amyloid by magnetic resonance imaging. Abstract #463.7
  Wisniewski TM, Wadghiri YZ, Elliott JI, Pappolla MA, Duff K, Turnbull DH, Sigurdsson EM, Society for Neuroscience, 11/1/2001
• Cholesterol metabolism: a potential target for Alzheimer’s disease therapy. Abstract #583.7
  Refolo LM, Petanceska SS, Derosa S, Olm V, La Francois J, Malester B, Bryant-Thomas T, Tint GS, Wang R, Ramabhadran R, Duff KEK, Pappolla MA, Society for Neuroscience, 11/1/2001
• Hypercholesterolemia is an early risk factor in the development of human amyloid pathology. Abstract # 583.10
  Pappolla MA, Manjon M, Bryant-Thomas T, Girones X, Ross A, Creekmore T, Matsubara E, Duff K, Cruz-Sanchez F, Refolo L, Society for Neuroscience, 11/1/2001
• Melatonin Dramatically Inhibits the Time Dependent Elevation of Beta-amyloid in a Transgenic Mouse Model of Alzheimer’s Disease.
  Matsubara E, Poeggeler B, Manjon M, Thomas T, Cruz-Sanchez F, Chyan Y-J, Leone A, Shoji M, Buxbaum J, Herbert D, Frangione B, Ghiso J, Pappolla MA, International Congress of Neuropathology., 9/1/2000
• Hypercholesterolemia Accelerates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer’s Amyloidosis. Abstract #566
  Refolo LM, Pappolla MA, Wang R, Tint S, Sambamurti, Malester BT, Francois JL, Duff K, Neurobiol Disease, 5/1/2000
• Melatonin Reverses the Pro-Fibrillogenic Activity of Apolipoprotein E. Abstract #856
  Pappolla MA, Poeggeler B, J-Y Chyan, Bryant-Thomas T, Miravalle L, Neurobiol Disease, 5/1/2000
• Amyloid ABeta (1-40) and ABeta(1-42) Adopt Remarkably Stable, Monomeric, and Extended Structures in Water Solution at Neutral pH. Abstract #48
  Zagorski MG, Shao H, Ma K, Yang, Li H, Zeng H, Zhang Y, Pappolla MA, Neurobiol Disease, 5/1/2000
• Induction of NADPH Cytochrome P450 Reductase by Amyloid Beta Protein: Friend or Foe of Neurons? Abstract #88
  MA Pappolla, Y-J Chyan, P Bozner, B Poeggeler, B Frangione, K Hsiao, RA Omar, G Perry, MA Smith, J Ghiso, J Neuropathol Exp Neurol, 1/1/1999
• Direct Scavenging of Carbonate Radicals by Melatonin. Identification of a New Neuroprotective Pathway Against Beta-amyloid Toxicity. Abstract #10
  Poeggeler B, MA Pappolla et al, J Neuropathol Exp Neurol, 1/1/1999
• Neuroprotection by Melatonin Against ABeta toxicity is not Mediated by Melatonin Receptors. Abstract #86
  Chyan Y-C, Poeggeler B, Omar RA, Ghiso J, Pappolla, J Neuropathol Exp Neurol, 1/1/1999
• NADPH Cytochrome P450 Reductase Mediates Oxidative Stress Induced by the Amyloid Beta Protein.
  Pappolla MA, Chyan Y-J, Bozner P, Martin B, Frangione B, Hsiao K, Omar RA, Perry G, Smith MA, Shiso J, Society for Neuroscience 28th Annual Meeting, Los Angeles, CA., 11/1/1998
• Chyan Y-J, Poeggeler B, Dubocovich M, Bick R, Omar RA, Frangione B, Soto C, Ghiso J, Pappolla MA, Society for Neuroscience 28th Annual Meeting, Los Angeles, CA., 11/1/1998
• Oxidative Stress in a Transgenic Model of Alzheimer’s Disease.
  Bozner P, Chyan Y-J, Hsiao K, Omar R, Perry G, Smith M, Ghiso J, Pappolla MA, Society for Neuroscience 28th Annual Meeting, Los Angeles, CA., 11/1/1998
• The Solution Structures of the Amyloid beta-(1-40) and beta-(1-42) Peptides and the Utility of MNR in the Design of Beta-Amyloid Inhibitors. Abstract #181
  Zaborski MG, Shao H, Ma K, Yang M, Pappolla MA, Neurobiology of Aging, 1/1/1998
• Oxidative Stress in Alzheimer’s Disease: A Transgenic Mouse Model. Abstract #1216
  Omar R, Bozner P, Chyan Y-J, Hsiao K, Perry G, Smith M, Ghiso J, Pappolla MA, Neurobiology of Aging, 1/1/1998
• Inhibition of Alzheimer Beta-fibrillogenesis by Melatonin. Abstract #480
  Pappolla MA, Bozner P, Soto C, Shao H, Zaborski MG, Chyan Y-J, Robakis NK, Frangione B, Ghiso J, Neurobiology of Aging, 1/1/1998
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Lectures

• "Interventional Pain Modalities for Spine Care. A Short Review". (Invited Speaker) 
  Charleston Spine Symposium. - 8/24/2007
• Cholesterol metabolism, hyperhomocysteinemia and oxidative stress: Novel therapeutic targets for Alzheimer’s disease. (Invited Symposium Speaker) 
  9th International Conference on Alzheimer’s Disease and Related Disorders, Philadelphia, PA. - 7/1/2004
• Cholesterol metabolism: A risk factor and potential therapeutic target for Alzheimer’s disease. (Invited Symposium Speaker) 
  8th International Conference on Alzheimer’s Disease and Related Disorders, Stockholm, Sweden. - 7/20/2002
• Hypercholesterolemia is an early risk factor in the development of human amyloid pathology. (Symposium Speaker) 
  31st Annual Meeting of the Society for Neuroscience, San Diego, CA. - 11/10/2001
• Hypercholesterolemia Accelerates Amyloid Pathology In A Transgenic Mouse Model Of Alzheimer’s Amyloidosis. (Invited Speaker) 
  001 European Congress of Clinical Investigation, Barcelona, Spain. - 5/5/2001
• Melatonin Reduces ABeta Accumulation in a Transgenic Mouse Model of Alzheimer’s Disease. 
  Selected presentation for the Hot Topics Symposium of the 2000 World Congress of Alzheimer’s Disease - 1/16/2001
• Biological Bases of Current Therapeutic Trends in Alzheimer’s Disease. (Invited Grand Rounds Speaker) 
  University of Alabama at Birmingham, Birmingham, AL. - 1/1/2001
• Melatonin Reverses the Pro-Fibrillogenic Activity of Apolipoprotein E. 
  World Alzheimer’s Congress. Washington, DC. - 7/1/2000
• Amyloid ABeta (1-40) and ABeta(1-42) Adopt Remarkably Stable, Monomeric, and Extended Structures in Water Solution at Neutral pH. 
  World Alzheimer’s Congress. Washington, DC. - 7/1/2000
• Hypercholesterolemia Accelerates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer’s Amyloidosis. 
  Annual Meeting of the American Association of Neuropathologists, Atlanta, GA. - 6/10/2000
• Biological Bases of Current Therapeutic Trends in Alzheimer’s disease. (Invited Speaker) 
  Mobile Neurological Society, Mobile, AL. - 5/1/2000
• Induction of NADPH Cytochrome P450 Reductase by Amyloid Beta Protein: Friend or Foe of Neurons? 
  Annual Meeting of the American Society of Neuropathologists, Portland, OR. - 1/1/1999
• Direct Scavenging of Carbonate Radicals by Melatonin. Identification of a New Neuroprotective Pathway Against Beta-amyloid Toxicity. 
  Annual Meeting of the American Society of Neuropathologists, Portland, OR. - 1/1/1999
• Neuroprotection by Melatonin Against ABeta toxicity is not Mediated by Melatonin Receptors. 
  Annual Meeting of the American Society of Neuropathologists, Portland, OR. - 1/1/1999
• The oxidative stress hypothesis of Alzheimer’s disease. (Invited Speaker) 
  European Congress of Neuropathology, Barcelona, Spain. - 1/1/1999
• The role of melatonin in Alzheimer’s. (Invited Speaker) 
  European Congress of Neuropathology, Barcelona, Spain. - 1/1/1999
• Indole Analogues as Potential Therapeutic Agents in Neurodegenerative Disease. (Invited Speaker) 
  Harvard Club-New York University, New York, NY. - 1/1/1998
• Role of Melatonin on Oxidative Neurotoxicity. (Invited Speaker) 
  New York University, Department of Pathology, New York, NY, 1997; (Invited Groundrounds Speaker) Mou - 1/1/1997
• Melatonin and its possible role in Alzheimer’s disease. (Invited Symposium Speaker) 
  The Gerontological Society of America 49th Annual Scientific Meeting, Washington, DC. - 1/1/1996
• The Oxidative Stress/Heat Shock Connection. Relevance to Alzheimer's Disease. (Invited Speaker) 
  Neurodegenerative Disorders: Common Molecular Mechanisms, Decade of the Brain Midpoint, Ocho Rios, J - 1/1/1995
• Grading of Central Nervous System Tumors. (Invited Speaker) 
  Argentine Congress of Pathology, Buenos Aires, Argentina. - 1/1/1995
• The Heat-Shock/Oxidative Stress Connection: Production Of Free, Radicals By Hyperthermia. 
  Fourth International Conference on Alzheimer's Disease and Related Disorders. - 1/1/1994
• Heat Shock Induces Miscompartmentalization of the Amyloid Precursor Protein (APP). 
  XIIth International Congress of Neuropathology. - 1/1/1994
• Glycosylation is not Required for Secretory Processing of the Alzheimer's Amyloid Precursor Protein (APP). 
  XIIth International Congress of Neuropathology. - 1/1/1994
• Neuropathology of Epilepsy. (Invited Speaker) 
  Argentine Congress of Pathology-Cordoba, Argentina. - 1/1/1994
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Other

• Cholesterol, Oxidative Stress and Alzheimer’s disease. Expanding the Horizons of Pathogenesis. (Review) 
  Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM, Free Radic Biol Med
  1/1/2002
• Inhibition of Alzheimer’s Beta Amyloid Fibril Formation. 
  Pappolla M, Bozner P, Zagorski M, Shao H, Frangione B, Ghiso J, Emerging Therapeutic Targets.
  1/1/1997
• Oxygen Free Radicals and Amyloidosis in Alzheimer's Disease: Is There a Connection? Editorial. 
  Robakis NK, Pappolla MA, Neurobiol Aging
  1/1/1994