MinsigChoiMD

Oncology • Stony Brook, NY

Gastrointestinal Cancer, Hematologic Oncology

Associate Professor, Stony Brook University School of Medicine

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Office
Nicolls Rd
Stony Brook, NY 11794
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Education & Training

Detroit Medical Center/Wayne State UniversityFellowship, Hematology and Medical Oncology, 2003 - 2006
Chicago Medical School/Rosalind Franklin University of Medicine & ScienceResidency, Internal Medicine, 2000 - 2003
Far Eastern University Nicanor Reyes Medical FoundationClass of 1998

Certifications & Licensure

NY State Medical License 2014 - 2025
KY State Medical License 2022 - 2025
MI State Medical License 2003 - 2016
IL State Medical License 2000 - 2003
American Board of Internal Medicine Medical Oncology

Clinical Trials

E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors and Previously Untreated Gastric Cancer Start of enrollment: 2011 Nov 01
Terminated
Phase 1, Phase 2
Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer) Start of enrollment: 2011 Aug 17
Completed
Phase 1
Fosaprepitant Dimeglumine in Preventing Nausea and Vomiting in Patients With Gastrointestinal Cancer Receiving Combination Chemotherapy Start of enrollment: 2012 Jun 01
Completed
Not Applicable
Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer Start of enrollment: 2012 Mar 01
Completed
Not Applicable
A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer Start of enrollment: 2016 May 19
Active, not recruiting
Phase 2
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers Start of enrollment: 2019 Feb 07
Active, not recruiting
Phase 3
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer Start of enrollment: 2019 May 10
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

ASO Visual Abstract: A Multicenter, Phase 1, Trial Evaluating Nanoliposomal Irinotecan for Heated Intraperitoneal Chemotherapy Combined with Cytoreductive Surgery in P...
Minsig Choi, Megan M Harper, Prakash K Pandalai, Sherif R Z Abdel-Misih, Reema A Patel, Carleton S Ellis, Ellen Reusch, Jeri Reynolds, Caterina Vacchi-Suzzi, Jinha M P...> ;Annals of Surgical Oncology. 2023 Feb 1
A Multicenter Phase 1 Trial Evaluating Nanoliposomal Irinotecan for Heated Intraperitoneal Chemotherapy Combined with Cytoreductive Surgery for Patients with Peritonea...
Minsig Choi, Megan M Harper, Prakash K Pandalai, Sherif R Z Abdel-Misih, Reema A Patel, Carleton S Ellis, Ellen Reusch, Jeri Reynolds, Caterina Vacchi-Suzzi, Jinha M P...> ;Annals of Surgical Oncology. 2023 Feb 1
3 citations
Perioperative chemotherapy versus adjuvant chemotherapy strategies in resectable gastric and gastroesophageal cancer: A Markov decision analysis.
Minsig Choi, Sayaka Ishizawa, David N. Kraemer, Aaron R. Sasson, Eugene A. Feinberg> ;European Journal of Surgical Oncology. 2021 Aug 17
33 citations
Clinical and immune responses to anti-CD3 x anti-EGFR bispecific antibody armed activated T cells (EGFR BATs) in pancreatic cancer patients.
Lawrence G. Lum, Archana Thakur, Minsig Choi, Abhinav Deol, Vidya Kondadasula, Dana L Schalk, Kristie Fields, Melissa Dufrense, Philip A. Philip, Gregory Dyson, Hussei...> ;Oncoimmunology. 2020 Jun 10
Correction: Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer
Mei Gao, Miranda Lin, Richard A. Moffitt, Marcela d'Alincourt Salazar, Jinha M. Park, Jeffrey Vacirca, Chuan Huang, Kenneth R. Shroyer, Minsig Choi, Georgios V. Georga...> ;British Journal of Cancer. 2020 May 11
10 citations
Comparative single-cell RNA sequencing (scRNA-seq) reveals liver metastasis-specific targets in a patient with small intestinal neuroendocrine cancer.
Manisha Rao, Ki Oh, Richard A. Moffitt, Patricia A. Thompson, Jinyu Li, Jingxuan Liu, Aaron R. Sasson, George Georgakis, Joseph Kim, Minsig Choi, Scott Powers> ;Cold Spring Harbor Molecular Case Studies. 2020 Apr 1
20 citations
Identification of targetable BRAF ΔN486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma.
Kazimierz O. Wrzeszczynski, Sadia Rahman, Mayu O. Frank, Kanika Arora, Minita Shah, Heather Geiger, Vanessa Felice, Dina Manaa, Esra Dikoglu, Depinder Khaira, A. Rao C...> ;Cold Spring Harbor Molecular Case Studies. 2019 Dec 13
2 citations
Fluoridation and county-level secondary bone cancer among cancer patients 18 years or older in New York State
Natalie Crnosija, Minsig Choi, Jaymie R. Meliker> ;Environmental Geochemistry and Health. 2019 Apr 1
12 citations
Spotlight on liposomal irinotecan for metastatic pancreatic cancer: patient selection and perspectives
Wonhee Woo, Edward T Carey, Minsig Choi> ;Oncotargets and Therapy. 2019 Feb 21
29 citations
Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer
Mei Gao, Miranda Lin, Richard A. Moffitt, Marcela d'Alincourt Salazar, Jinha M. Park, Jeffrey Vacirca, Chuan Huang, Kenneth R. Shroyer, Minsig Choi, Georgios V. Georga...> ;British Journal of Cancer. 2019 Jan 1
45 citations
Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues.
Mei Gao, Miranda Lin, Manisha Rao, Hannah Thompson, Kelsi Hirai, Minsig Choi, Georgios V. Georgakis, Aaron R. Sasson, Juan Carlos Bucobo, Demetri Tzimas, Lionel S. D’S...> ;Annals of Surgical Oncology. 2018 Jul 12
6 citations
Assessing Clinical Outcomes in Colorectal Cancer with Assays for Invasive Circulating Tumor Cells.
Yue Zhang, Kevin Zarrabi, Wei Hou, Stefan Madajewicz, Minsig Choi, Stanley Zucker, Wen-Tien Chen> ;Biomedicines. 2018 Jun 6
7 citations
Multiregion Comprehensive Genomic Profiling of a Gastric Mixed Neuroendocrine-Nonneuroendocrine Neoplasm with Trilineage Differentiation
Faheem Farooq, Kevin Zarrabi, Keith Sweeney, Joseph Kim, Jela Bandovic, Chiraag Patel, Minsig Choi> ;Journal of Gastric Cancer. 2018 Jun 1
26 citations
Challenges in Ras therapeutics in pancreatic cancer.
Minsig Choi, Harold Bien, Adaobi Mofunanya, Scott Powers> ;Seminars in Cancer Biology. 2017 Nov 1
31 citations
A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal ...
Daniel W. Bowles, Mark D. Kochenderfer, Allen Lee Cohn, Lucas Sideris, Nghia Nguyen, Vivian Jean Mikao Cline-Burkhardt, Ian D. Schnadig, Minsig Choi, Lisle Nabell, Arv...> ;Clinical Colorectal Cancer. 2016 Dec 1
1 citations
Liposomal Irinotecan in the Treatment of Refractory Pancreatic Cancer.
Harold Bien, Gerardo G. Mackenzie, Minsig Choi> ;Recent Patents on Anti-Cancer Drug Discovery. 2016 Oct 31
14 citations
Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers
Robert Matthews, Minsig Choi> ;Diagnostics. 2016 Sep 9
17 citations
Neoadjuvant vs. adjuvant treatment of Siewert type II gastroesophageal junction cancer: an analysis of data from the surveillance, epidemiology, and end results (SEER)...
Joseph A. Miccio, Oluwadamilola T. Oladeru, Jie Yang, Yaqi Xue, Minsig Choi, Hannah Yoon, Samuel Ryu, A. Stessin> ;Journal of Gastrointestinal Oncology. 2016 Jun 1
12 citations
Immune Therapy in Pancreatic Cancer: Now and the Future?
Yue Zhang, Minsig Choi> ;Reviews on Recent Clinical Trials. 2015 Jan 1
10 citations
Second-Line Treatment of Advanced Gastric Cancer: Where Do We Stand?
Amit Mahipal, Minsig Choi, Richard Kim> ;Journal of the National Comprehensive Cancer Network. 2015 Oct 1
10 citations
PET scans as a predictive marker of survival in advanced colorectal cancer.
Minsig Choi, Sri Lakshmi S. Kollepara, Lance K. Heilbrun, Daryn Smith, Anthony F. Shields, Philip A. Philip> ;Clinical Colorectal Cancer. 2015 Mar 1
72 citations
A randomized, phase II trial of cetuximab with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic...
Antonio Jimeno, Keisuke Shirai, Minsig Choi, J. Laskin, Mark D. Kochenderfer, Alexander I. Spira, Vivian Jean Mikao Cline-Burkhardt, Eric Winquist, Diana F. Hausman, L...> ;Annals of Oncology. 2015 Mar 1
12 citations
Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or l...
Andre Konski, Joshua E. Meyer, Michael C. Joiner, Michael J. Hall, Philip A. Philip, Anthony F. Shields, E. McSpadden, Minsig Choi, Beth Adaire, Gail Duncan, Neal J. M...> ;Radiotherapy and Oncology. 2014 Oct 1
20 citations
Ipilimumab augments antitumor activity of bispecific antibody-armed T cells
Hiroshi Yano, Archana Thakur, Elyse N. Tomaszewski, Minsig Choi, Abhinav Deol, Lawrence G. Lum> ;Journal of Translational Medicine. 2014 Jul 9
22 citations
Neo-adjuvant therapy for hepatocellular carcinoma before liver transplantation: where do we stand?
Masato Fujiki, Federico Aucejo, Minsig Choi, Richard D. Kim> ;World Journal of Gastroenterology. 2014 May 14
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Press Mentions

Pancreatic Cancer Drug Developed by Stony Brook University Moves into Phase III Clinical TrialsOctober 23rd, 2019
Vitamin D Linked to Lower Risk of Colorectal CancerJune 20th, 2018