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Mitchell Brin, MD, Neurology, Irvine, CA, UCI Health

MitchellBrinMDFAAN, FAHS, FANA

Neurology Irvine, CA

Movement Disorder

Sr. VP Development & Chief Scientific Officer BOTOX & Neurotoxins, Allergan & Professor of Neurology, UC Irvine

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Education & Training

  • Columbia University Neurologic Institute
    Columbia University Neurologic InstituteFellowship, Movement Disorders, 1983 - 1986
  • New York Presbyterian Hospital (Columbia Campus)
    New York Presbyterian Hospital (Columbia Campus)Residency, Neurology, 1980 - 1983
  • Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital
    Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalInternship, Internal Medicine, 1979 - 1980
  • Columbia University Vagelos College of Physicians and Surgeons
    Columbia University Vagelos College of Physicians and SurgeonsClass of 1979

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 2001 - 2025
  • NY State Medical License
    NY State Medical License 1980 - 2024
  • American Board of Psychiatry and Neurology Neurology

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Botulinum neurotoxin type A-cleaved SNAP25 is confined to primary motor neurons and localized on the plasma membrane following intramuscular toxin injection  
    Cai BB, Francis J, Brin MF, Broide RS, Neuroscience, 1/1/2017
  • Repeated onabotulinumtoxinA treatment of glabellar lines at rest over three treatment cycles  
    Carruthers A, Carruthers J, Fagien S, Lei X, Kolodziejczyk J, Brin MF, Dermatol.Surg., 1/1/2016
  • Impact of cervical dystonia on work productivity: an analysis from a patient registry  
    Molho ES, Stacy M, Gillard P, Charles D, Adler CH, Jankovic J, Schwartz M, Brin MF, Mov Disord.Clin.Pract., 1/1/2016
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Books/Book Chapters

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Abstracts/Posters

  • Effects of onabotulinumtoxinA treatment on the chronic migraine comorbidities of depression, anxiety, sleep and fatigue
    Brin MF, Manack Adams A, Interagency Botulism Research Coordinating Committee - 54th Annual Meeting, Burlingame, CA, 1/22/2017
  • The psychological impact of horizontal frontalis lines, glabellar lines, and lateral canthal lines: qualitative, patient-centered studies
    Brin MF, Dayan S, Yoelin SG, De Boulle K, Garcia J, Ferrusi IL, Interagency Botulism Research Coordinating Committee - 54th Annual Meeting, Burlingame, CA, 1/22/2017
  • Botulinum neurotoxin type A�cleaved SNAP25 is confined to primary motor neurons and expressed on the plasma membrane following intramuscular toxin injection
    Broide R, Cai B, Francis J, Brin MF, Society for Neuroscience - 46th Annual Meeting; International Neurotoxin Association - 3rd Conference (TOXINS), San Diego, CA, 2016; Madrid, Spain, 2017, 1/18/2017
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Other

  • The Role of Chemodenervation in Spasticity Management (Videotape) 
    Brin MF, O'Brien CF, Gormley ME, McGuire J, Blazer J, WE MOVE
    www.wemove.org
    New York, NY - 1/1/2000
  • New Advances in the Management of Spasticity and Muscle Overactivity (CD Rom) 
    Esquenazi A, Mayer N, Professional Postgraduate Services
    Knoxville, TN - 1/1/2000
  • Advances in dystonia: Classification, genetics and therapeutics 
    Brin MF, Neuroscience Year: Supplement to the Encyclopedia of Neuroscience
    1/1/1999
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Press Mentions

  • AbbVie Announces Late-Breaking Results from Phase 2 Exploratory NOVA Trial of Novel Investigational Neurotoxin AGN-151607 for the Prevention of Postoperative Atrial Fibrillation in Cardiac Surgery Patients
    AbbVie Announces Late-Breaking Results from Phase 2 Exploratory NOVA Trial of Novel Investigational Neurotoxin AGN-151607 for the Prevention of Postoperative Atrial Fibrillation in Cardiac Surgery PatientsNovember 9th, 2022
  • Botox Approved to Treat Spasticity in 8 New Arm, Hand Muscles
    Botox Approved to Treat Spasticity in 8 New Arm, Hand MusclesAugust 2nd, 2021
  • AbbVie Adds to the Botox War Chest with a 12th FDA Approval — but Competition Is Fast Approaching
    AbbVie Adds to the Botox War Chest with a 12th FDA Approval — but Competition Is Fast ApproachingFebruary 10th, 2021
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Professional Memberships

Hospital Affiliations