MohamedElsayed AhmedSalemMD

PubMed

• Differential responses to immune checkpoint inhibitors are governed by diverse mismatch repair gene alterations.
  Khushman, M., Toboni, M., Xiu, J., Manne, U., Farrell, A., Lou, E., Shields, A., Philip, P., Salem, M., Abraham, J., Spetzler, D., Marshall, J., Jayachandran, P., Hall...> ;Clinical Cancer Research. 2024 Feb 13
• 4 citations
  Multi-omic Characterization of Pancreatic Ductal Adenocarcinoma Relates CXCR4 mRNA Expression Levels to Potential Clinical Targets.
  Florian Kocher, Alberto Puccini, Gerold Untergasser, Agnieszka Martowicz, Kai Zimmer, Andreas Pircher, Yasmine Baca, Joanne Xiu, Johannes Haybaeck, Piotr Tymoszuk, Ric...> ;Clinical Cancer Research. 2022 Nov 14
• 2 citations
  Phase II Single-Arm Study of Palbociclib and Cetuximab Rechallenge in Patients with KRAS/NRAS/BRAF Wild-Type Colorectal Cancer.
  Jonathan D Sorah, Dominic T Moore, Matthew J Reilley, Mohamed E Salem, Tammy Triglianos, Hanna K Sanoff, Autumn J McRee, Michael S Lee> ;The Oncologist. 2022 Dec 9
• 15 citations
  Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets.
  Alberto Puccini, Kelsey Poorman, Fabio Catalano, Andreas Seeber, Richard M Goldberg, Mohamed E Salem, Anthony F Shields, Martin D Berger, Francesca Battaglin, Ryuma To...> ;Oncogene. 2022 Jun 1
• 26 citations
  Immune Checkpoint Blockade Therapy in Patients With Colorectal Cancer Harboring Microsatellite Instability/Mismatch Repair Deficiency in 2022.
  Thierry André, Romain Cohen, Mohamed E Salem> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2022 Apr 1
• 37 citations
  Landscape of, Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in-Mutated Cancers.
  Mohamed E Salem, Sherif M El-Refai, Wei Sha, Alberto Puccini, Axel Grothey, Thomas J George, Jimmy J Hwang, Bert O'Neil, Alexander S Barrett, Kunal C Kadakia, Laura W ...> ;JCO Precision Oncology. 2022 Mar 1
• 2 citations
  Association of Homologous Recombination-DNA Damage Response Gene Mutations with Immune Biomarkers in Gastroesophageal Cancers.
  Michael Cerniglia, Joanne Xiu, Axel Grothey, Michael J. Pishvaian, Yasmine Baca, Jimmy J. Hwang, John L. Marshall, Ari M. Vanderwalde, Anthony F. Shields, Heinz-Josef ...> ;Molecular Cancer Therapeutics. 2021 Nov 1
• 7 citations
  Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients.
  Alberto Puccini, Andreas Seeber, Joanne Xiu, Richard M. Goldberg, Davide Soldato, Axel Grothey, Anthony F. Shields, Mohamed E. Salem, Francesca Battaglin, Martin D. Be...> ;NPJ Precision Oncology. 2021 Oct 27
• 13 citations
  Impact of Sociodemographic Disparities and Insurance Status on Survival of Patients with Early-Onset Colorectal Cancer.
  Mohamed E. Salem, Alberto Puccini, Sally Jeanne Trufan, Wei Sha, Kunal C. Kadakia, Marion L. Hartley, Laura W. Musselwhite, James T. Symanowski, Jimmy J. Hwang, Derek ...> ;The Oncologist. 2021 Oct 1
• 8 citations
  Molecular characterization of squamous cell carcinoma of the anal canal
  Samantha A Armstrong, Rita Malley, Hongkun Wang, Heinz-Josef Lenz, David Arguello, Wafik S. El-Deiry, Joanne Xiu, Zoran Gatalica, Jimmy J. Hwang, Philip A. Philip, Ant...> ;Journal of Gastrointestinal Oncology. 2021 Oct 1
• 5 citations
  Re-Evaluating Disease-Free Survival as an Endpoint vs Overall Survival in Stage III Adjuvant Colon Cancer Trials
  Jun Yin, Mohamed E. Salem, Jesse G. Dixon, Zhaohui Jin, Romain Cohen, Aimery de Gramont, Eric Van Cutsem, Julien Taieb, Steven R. Alberts, Norman Wolmark, Hans-Joachim...> ;Journal of the National Cancer Institute. 2021 Sep 10
• 2 citations
  Early-onset pancreatic cancer: an institutional series evaluating end-of-life care.
  Kunal C. Kadakia, Sally Jeanne Trufan, Megan Jagosky, William M Worrilow, Bradley W. Harrison, Katherine Broyhill, Jimmy J. Hwang, Laura W. Musselwhite, Aynur Aktas, D...> ;Supportive Care in Cancer. 2021 Jul 1
• 3 citations
  Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of KRAS.
  Emil Lou, Joanne Xiu, Yasmine Baca, Andrew C. Nelson, Benjamin A. Weinberg, Muhammad Shaalan Beg, Mohamed E. Salem, Heinz-Josef Lenz, Philip A. Philip, Wafik S. El-Dei...> ;Cells. 2021 May 21
• 9 citations
  Colorectal Cancer: In the Pursuit of Health Equity.
  Laura W. Musselwhite, Folasade P. May, Mohamed E. Salem, Edith P Mitchell> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2021 May 19
• Role of Immune Checkpoint Inhibitors in Understudied Populations.
  Kunal C. Kadakia, Mohamed E. Salem> ;JCO Oncology Practice. 2021 Apr 8
• 22 citations
  Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer.
  Jim Abraham, Daniel Magee, Chiara Cremolini, Carlotta Antoniotti, David D. Halbert, Joanne Xiu, Phillip Stafford, Donald A. Berry, Matthew J. Oberley, Anthony F. Shiel...> ;Clinical Cancer Research. 2021 Feb 15
• 36 citations
  Prevalence of class I-III BRAF mutations among 114,662 cancer patients in a large genomic database.
  Jeff Owsley, Matthew K Stein, Jason Porter, Gino K. In, Mohamed E. Salem, Steven J. O'Day, Andrew Elliott, Kelsey Poorman, Geoffrey T. Gibney, Ari M. Vanderwalde> ;Experimental Biology and Medicine. 2021 Jan 1
• 73 citations
  Relationship between MLH1, PMS2, MSH2 and MSH6 gene-specific alterations and tumor mutational burden in 1057 microsatellite instability-high solid tumors.
  Mohamed E. Salem, J. Nicholas Bodor, Alberto Puccini, Joanne Xiu, Richard M. Goldberg, Axel Grothey, W. Michael Korn, Anthony F. Shields, William M Worrilow, Edward S....> ;International Journal of Cancer. 2020 Nov 15
• 39 citations
  Comprehensive genomic profiling of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs)
  Alberto Puccini, Kelsey Poorman, Mohamed E. Salem, Davide Soldato, Andreas Seeber, Richard M. Goldberg, Anthony F. Shields, Joanne Xiu, Francesca Battaglin, Martin D. ...> ;Clinical Cancer Research. 2020 Nov 15
• 58 citations
  Molecular profile of BRCA-mutated biliary tract cancers
  Gilbert Spizzo, Alberto Puccini, Joanne Xiu, Richard M. Goldberg, Axel Grothey, Anthony F. Shields, Sukeshi Patel Arora, Moh’d Khushman, Mohamed E. Salem, Francesca Ba...> ;ESMO Open. 2020 Jun 1
• 10 citations
  WRN-Mutated Colorectal Cancer Is Characterized by a Distinct Genetic Phenotype.
  Kai Zimmer, Alberto Puccini, Joanne Xiu, Yasmine Baca, Gilbert Spizzo, Heinz-Josef Lenz, Francesca Battaglin, Richard M. Goldberg, Axel Grothey, Anthony F. Shields, Mo...> ;Cancers. 2020 May 22
• 25 citations
  Molecular Analyses of Left‐ and Right‐Sided Tumors in Adolescents and Young Adults with Colorectal Cancer
  Mohamed E. Salem, Francesca Battaglin, Richard M. Goldberg, Alberto Puccini, Anthony F. Shields, David Arguello, W. Michael Korn, John L. Marshall, Axel Grothey, Heinz...> ;The Oncologist. 2020 May 1
• 24 citations
  Overcoming resistance to anti-PD1 and anti-PD-L1 treatment in gastrointestinal malignancies.
  Alberto Puccini, Francesca Battaglin, Maria Laura Iaia, Heinz-Josef Lenz, Mohamed E. Salem> ;Journal for Immunotherapy of Cancer. 2020 May 1
• 6 citations
  Prognostic value of tumor mutation burden (TMB) and INDEL burden (IDB) in cancer: current view and clinical applications
  Anwaar Saeed, Mohamed E. Salem> ;Annals of Translational Medicine. 2020 Apr 27
• 22 citations
  Evaluation of the change of outcomes over a 10-year period in patients with stage III colon cancer: pooled analysis of 6501 patients treated with fluorouracil, leucovo...
  Mohamed E. Salem, Jun Yin, Richard M. Goldberg, Levi Pederson, Norman Wolmark, Steven R. Alberts, Julien Taieb, John L. Marshall, Sara Lonardi, Takayuki Yoshino, Rache...> ;Annals of Oncology. 2020 Apr 1
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