MohammadOmarHussainiMD

PubMed

• Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML.
  Onyee Chan, Najla Al Ali, Hammad Tashkandi, Austin Ellis, Somedeb Ball, Justin Grenet, Caroline Hana, Yehuda Deutsch, Ling Zhang, Mohammad Hussaini, Jinming Song, Seon...> ;Blood Advances. 2024 Mar 12
• Chimeric antigen receptor T-cells might unmask transdifferentiated histiocytic sarcoma during diffuse large B-cell lymphoma treatment.
  Curtis Gravenmier, Bijal Shah, Mohammad Hussaini, Ling Zhang> ;Leukemia & Lymphoma. 2024 May 1
• Sclerotic marginal zone lymphoma: A case report.
  Zade Moureiden, Hammad Tashkandi, Mohammad Omar Hussaini> ;World Journal of Methodology. 2023 Sep 20
• Profiling endogenous, environmental, and infectious disease mutational signatures in blastic plasmacytoid dendritic cell neoplasms.
  Corinn Small, Soham Mukerjee, Diwash Jangam, Sumanth Gollapudi, Kunwar Singh, David L Jaye, Phyu P Aung, Christiane Querfeld, Keluo Yao, Karen M Chisholm, Sheeja Pulla...> ;International Journal of Laboratory Hematology. 2023 Oct 1
• 1 citations
  Co-mutation ofandPredicts Poorer Overall Survival Than IsolatedorMutations.
  Jinming Song, Lynn Moscinski, Ethan Yang, Haipeng Shao, Mohammad Hussaini, Hailing Zhang> ;In Vivo. 2023 Apr 27
• 1 citations
  Clinicopathologic characteristics, genetic features, and treatment options for acute lymphoblastic leukemia with JAK2 rearrangement-A 10-case study and literature review.
  Ling Zhang, Bijal Shah, Yumeng Zhang, Hammad Tashkandi, Wenbin Xiao, Sebastian Fernandez-Pol, Maria Vergara-Lluri, Mohammad Hussaini, Jinming Song, Jeffrey Lancet, Lyn...> ;Human Pathology. 2023 Jun 1
• 4 citations
  U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes.
  Rami Komrokji, Luis E Aguirre, Najla Al Ali, Mohamad Hussaini, David Sallman, Dana Rollison, Eric Padron> ;Blood Advances. 2023 Jan 10
• 1 citations
  Clinical characteristics and outcomes of EZH2-mutant myelodysplastic syndrome: A large single institution analysis of 1774 patients.
  Somedeb Ball, Akriti G Jain, Najla Al Ali, Sara M Tinsley, Onyee Chan, Andrew T Kuykendall, Kendra Sweet, Jeffrey E Lancet, David A Sallman, Mohammad Omar Hussaini, Er...> ;Leukemia Research. 2023 Jan 1
• 2 citations
  Frontline treatment approaches in-aberrant mantle cell lymphoma.
  Franco Castillo-Tokumori, Junmin Whiting, David Boulware, Jose Sandoval-Sus, Todd C Knepper, Mohammad Hussaini, Jianguo Tao, Julio C Chavez, Leidy Isenalumhe, Sameh Ga...> ;Leukemia & Lymphoma. 2023 Jan 1
• 7 citations
  An Analysis of the Pathologic Features of Blastic Plasmacytoid Dendritic Cell Neoplasm Based on a Comprehensive Literature Database of Cases.
  Robert S Ohgami, Phyu P Aung, Alejandro A Gru, Mohammad Hussaini, Kunwar Singh, Christiane Querfeld, Kelou Yao, Corinn Small, Sumanth Gollapudi, David Jaye, Sa A Wang,...> ;Archives of Pathology & Laboratory Medicine. 2023 Jul 1
• Genomic Landscape of Mixed-Phenotype Acute Leukemia.
  Marah Hennawi, Nagehan Pakasticali, Hammad Tashkandi, Mohammad Hussaini> ;International Journal of Molecular Sciences. 2022 Sep 24
• 6 citations
  Molecular annotation of extramedullary acute myeloid leukemia identifies high prevalence of targetable mutations.
  Somedeb Ball, Todd C Knepper, Yehuda E Deutsch, Wassim Samra, Justin M Watts, Terrence J Bradley, Onyee Chan, Mohammad Omar Hussaini, Ling Zhang, Kendra L Sweet, Andre...> ;Cancer. 2022 Nov 1
• 28 citations
  Whole-genome sequencing reveals complex genomic features underlying anti-CD19 CAR T-cell treatment failures in lymphoma.
  Michael D Jain, Bachisio Ziccheddu, Caroline A Coughlin, Rawan Faramand, Anthony J Griswold, Kayla M Reid, Meghan Menges, Yonghong Zhang, Ling Cen, Xuefeng Wang, Moham...> ;Blood. 2022 Aug 4
• 3 citations
  The Application of NextGen Sequencing in the Diagnosis of Myeloid Neoplasms in Myeloma Patients With Cytopenia.
  Jinming Song, Hailing Zhang, Ning Dong, Xiaohui Zhang, Mohammad Hussaini, Akriti Jain, Lynn Moscinski, Ken Shain, Rachid Baz, Melissa Alsina, Taiga Nishihori, Ling Zhang> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Jun 1
• 2 citations
  Technological Advances:andInternal Tandem Duplication Mutations Can be Reliably Detected by Next Generation Sequencing.
  Ratilal Akabari, Dahui Qin, Mohammad Hussaini> ;Genes. 2022 Apr 1
• 5 citations
  Marrow ring sideroblasts are highly predictive for TP53 mutation in MDS with excess blasts.
  David M Swoboda, Rashmi Kanagal-Shamanna, Andrew M Brunner, Thomas Cluzeau, Onyee Chan, Najla Al Ali, Guillermo Montalban-Bravo, Quinto J Gesiotto, Alexander Gavralidi...> ;Leukemia. 2022 Apr 1
• Osteonectin/SPARC Expression in Head and Neck Squamous Cell Carcinoma: A Tissue Microarray Study.
  James S Lewis Jr, Wade L Thorstad, Mohammad Hussaini> ;Applied Immunohistochemistry & Molecular Morphology. 2022 Mar 29
• 1 citations
  Expanding diagnostic criteria: Multiorgan T-Cell/myeloid mixed phenotype acute leukemia with t(v;11q23)-rearrangement successfully treated by allogeneic stem cell tran...
  Suhayb Syed, Amy Song, Mohammad Hussaini> ;Leukemia Research Reports. 2022 Jan 1
• 8 citations
  "Alterations in the Skin Microbiota Are Associated With Symptom Severity in Mycosis Fungoides".
  Yumeng Zhang, Lucia Seminario-Vidal, Mohammad Hussaini, Jiqiang Yao, David Rutenberg, Youngchul Kim, Anna Giualiano, Lary A Robinson, Lubomir Sokol, Leah Cohen> ;Frontiers in Cellular and Infection Microbiology. 2022 Jan 1
• 1 citations
  Clinical characteristics and prognostic factors of 70 patients with Sézary syndrome: a single-institutional experience at Moffitt cancer center.
  Yumeng Zhang, Lucia Seminario-Vidal, Christa Varnadoe, Yuanyuan Lu, Ning Dong, Christopher Salamanca, Shannen Whiddon, Janice Bennett, Rebecca Hargis, Hien Liu, Michae...> ;Leukemia & Lymphoma. 2021 Sep 1
• Acquisition of IDH2 mutations in relapsed/refractory AML is associated with worse patient outcomes.
  Amy Song, Omar Altabbakh, David A. Sallman, Eric Padron, Chetasi Talati, Mohammad Hussaini> ;European Journal of Haematology. 2021 Aug 18
• 6 citations
  Assessment of Clonotypic Rearrangements and Minimal Residual Disease in Lymphoid Malignancies: A Large Cancer Center Experience Using clonoSEQ.
  Mohammad Hussaini, Jaya Srivastava, Lik Wee Lee, Taiga Nishihori, Bijal D. Shah, Melissa Alsina, Javier Pinilla-Ibarz, Kenneth H. Shain> ;Archives of Pathology & Laboratory Medicine. 2021 Aug 3
• 40 citations
  Baseline and serial molecular profiling predicts outcomes with hypomethylating agents in myelodysplastic syndromes.
  Anthony M. Hunter, Rami S. Komrokji, Seongseok Yun, Najla Al Ali, Onyee Chan, Jinming Song, Mohammad Hussaini, Chetasi Talati, Kendra Sweet, Jeffrey E. Lancet, Eric Pa...> ;Blood Advances. 2021 Feb 23
• 11 citations
  ELN 2017 Genetic Risk Stratification Predicts Survival of Acute Myeloid Leukemia Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation
  Doris K. Hansen, Jongphil Kim, Zachary J. Thompson, Mohammad Hussaini, Taiga Nishihori, Anam Ahmad, Hany Elmariah, Rawan Faramand, Asmita Mishra, Marco L. Davila, Farh...> ;Transplantation and Cellular Therapy. 2021 Mar 1
• 13 citations
  Genomic Characteristics and Prognostic Significance of Co-mutated ASXL1/SRSF2 Acute Myeloid Leukemia
  Daniel R. Richardson, David M Swoboda, Dominic T. Moore, Steven M Johnson, Onyee Chan, Jonathan Galeotti, Sonia Esparza, Mohammad Hussaini, Hendrick W. van Deventer, M...> ;American Journal of Hematology. 2021 Apr 1
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Journal Articles

• Sentinel case of richter transformation from chronic lymphocytic leukemia/small lymphocytic lymphoma to CD3+ diffuse large b-cell lymphoma  
  Ismail, M; Mallick, J; Qin, D; Hussaini, M, Journal of Clinical Pathology, 1/1/2017
• PRDM1 expression levels in Marginal Zone Lymphoma and Lymphoplasmacytic Lymphoma  
  M Hussaini, C Yeung, XP Zhu, A Mirza, J Pfeifer, A Hassan, Int J Clin Exp Pathol, 1/1/2017
• Allogeneic hematopoietic cell transplantation for Richter syndrome: a single-center experience  
  Mohamed A. Kharfan-Dabaja, Ambuj Kumar, Facundo Stingo, Farhad Khimani, Mohammad Hussaini, Ernesto Ayala, Taiga Nishihori, Bijal Shah, Frederick Locke, Javier Pinilla-..., Clinical Lymphoma, Myeloma and Leukemia, 1/1/2017
• Somatic Sequencing Identifies Trametinib-Responsive MDS and Finds Acquired CHIP  
  Cory M. Vela, Magali Van den Bergh, Nancy K. Gillis, Markus Ball, Mohammad O. Hussaini, Christine M. Walko, J. Kevin Hicks, Lia Perez , Eric Padron, Rami S. Komrokji, JCO Precision Oncology, 1/1/2017
• Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement: a Multicenter Experience  
  P Strati, Guilin Tang, DY Duose, M Hussaini, M Sayeef, R S Komrokji, S Oh, JMascarenhas, V Najfeld, V Subbiah, H Kantarjian, S Verstovsek, N Daver, Leukemia and Lymphoma, 1/1/2017
• Efficacy of high-dose therapy and autologous HCT in gray zone lymphoma with features intermediate between classical Hodgkin lymphoma and diffuse large B-cell lymphoma:...  
  M A Kharfan-Dabaja, R Raj, L Nikolaenko, S Ahmed, N Reddy, S Nathan, M Cherry, N El-Jurdi, C Obiozor, T Fenske, J Song, T Muzzafar, E Ayala, B Savani, M Khawandanah, ..., Biology of Blood and Marrow Transplantation, 1/1/2017
• Genetic landscape of Acute Myeloid Leukemia Interrogated by Next-Generation Sequencing: A Large Cancer Center Experience  
  M O Hussaini, S Mirza, E Padron, J Lancet, J Song, Cancer Genomics and Proteomics, 1/1/2017
• Comparison of the Mutational Profiles of Primary Myelofibrosis, Polycythemia Vera, and Essential Thrombocytosis  
  J Song, M Hussaini, E Padron, J Lancet, R Komorkji, L Moscinski, L Zhang, AJCP, 1/1/2016
• Biomarkers in Hematological Malignancies: A Review of Molecular Testing in Hematopathology  
  Mohammad Hussaini, MD, Cancer Control
• Biomarkers in hematologic malignancies: a review of molecular testing in hematopathology  
  Hussaini, MO, Cancer Control, 1/1/2015
• Richter syndrome: An unusual case of concurrent small lymphocytic lymphoma, Hodgkin lymphoma, and anaplastic plasmacytoma  
  M Hussaini, J Klein, J Xiao, F Kreisel, J Frater, A Hassan, J Appl Hematol, 1/1/2014
• Erdheim-Chester Disease Involving the Bone Marrow: A Discussion of Non-Langerhans Histiocytic Disorders  
  A Gru, J Frater, L. Dehner, A Hassan, F Kreisel, M Hussaini, T Nguyen, Pathology Case Reviews, 1/1/2012
• Impact of proliferative indices and tumor suppressor genes on treatment response in marginal zone lymphomas  
  M Hussaini, F Kreisel, A Hassan, Comparative Clinical Pathology, 1/1/2011
• Detection of novel t(12;17)(p12;p13) in relapsed refractory acute myeloid leukemia by anchored multiplex PCR(AMP)-based next generation sequencing  
  T Badar, L Johnson, K Trifilo, H Wang, B Kudlow, E Padron, P Pappenhausen, M Hussaini, Appl Immunohistochem Mol Morphol, 1/9./2017
• Who is Who?: Acquisition of Germline Variants in a Case of Allogeneic Stem Cell Transplant  
  Todd C. Knepper, James Saller, Asmita Mishra, Mohammad Hussaini, Howard L. McLeod, Rami S. Komrokji, Eric Padron, JCO Precision Oncology
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Books/Book Chapters

• Genomic Applications in Pathology 
  Chapter: Pharmacogenomics 
  M Hussaini and H. McLeodEdition 2nd,2017
• USMLE Amnesia Cure 
  Hussaini MFalcon PublishingEdition 1st,2009
• COMLEX Amnesia Cure 
  Hussaini MFalcon PublishingEdition 1st,2009
• Washington Manual of Surgical Pathology 
  Chapter: Spleen 
  Hussaini M, A HassanLLWEdition 2nd,
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Abstracts/Posters

• Clearance of Somatic Gene Mutations in Patients with Acute Myeloid Leukemia Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) Predicts Outcome
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• The Lymphoma Tumor Microenvironment Influences Toxicity after CD19 CAR T Cell Therapy
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Impact of TP53 gene Mutation Clearance and Conditioning Intensity on Outcome in MDS or AML Patients Prior to Allogeneic Stem Cell Transplantation
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Marrow Ring Sideroblasts Are Highly Predictive for TP53 Mutation in MDS with Excess Blasts
  Mohammad O Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• CSF3R Mutations Are Exceedingly Rare Genetic Events Associated with Inferior Survival and Sensitivity to Ruxolitinib across Myeloid Malignancies
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• RUNX1 Mutation Is Associated with Poor Outcome in Patients with Acute Myeloid Leukemia Receiving Allogeneic Stem Cell Transplantation
  Mohammad Hussaini, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Characterization of hematologic malignancies with Anchored Multiplex PCR and next-generation sequencing
  L Johnson, M Bessette, A Berlin, J Haimes, Ds Fugere, L M Griffin, K Trifilo, N Manoj, H Wang, R Ryan, M Hussaini, B Kudlow, 22nd European Hematology Association Congress, Madrid, Spain, 1/1/2017
• Prognostic Significance of Serial Molecular Annotation in Myelodysplastic Syndromes (MDS) and Secondary Acute Myeloid Leukemia (sAML)
  Seongseok Yun, Rami Komrokji, Najla Al Ali, Jinming Song, Christine Vaupel, Mohammad Hussaini, Kendra Sweet, Jeffrey Lancet, Jeff Hall, Alan List, Eric Padron, David S..., Clinical Lymphoma, Myeloma and Leukemia, 1/1/2017
• Prognostic Significance of Serial Molecular Annotation in Myelodysplastic Syndromes (MDS) and Secondary Acute Myeloid Leukemia (SAML)
  D. Sallman, S. Yun, N. Al Ali, J. Song, C. Vaupel, M. Hussaini, K. Sweet, J. Lancet, J. Hall, A. List, E. Padron, R. Kormokji, Leukemia Research, 1/1/2017
• JAK2-negative refractory anemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) occurs more commonly in women
  Hussaini M, AMP, 1/1/2017
• Detection of Novel t(12;17)(p12;p13) in Treatment-Refractory/Relapsed Acute Myeloid Leukemia by Anchored Multiplex PCR(AMP)-based Next Generation Sequencing
  L Johnson, P Papenhausen, M O Hussaini, AARC, 1/1/2016
• Novel t(X;21)(q26;q22) detected in a case of acute unclassifiable leukemia by application of anchored multiplex PCR- based Next Generation Sequencing
  L Johnson, P Papenhausen, M O Hussaini, AARC, 1/1/2016
• Impact of Persistent Somatic Mutations on Day 14 After Induction Chemotherapy for Acute Myeloid Leukemia
  K Sweet, M Hussaini, J Lancet, R Komrokji, A List, L Moscinski, J Song, E Padron, 1/1/2016
• Clinical Utility of Molecular Profiling in Higher Risk MDS Treated with Azacitidine: Can We Tailor Therapy Accordingly?
  D Sallman, E Padron, J Song, M Hussaini, C Vaupel, N H Al Ali, J E Lancet, J Hall, A List and R Komrokji, Blood, 1/1/2016
• Peripheral T-Cell Lymphoma Arising in a Patient With Prior T-Cell Acute Lymphoblastic Lymphoma: A Dyadic Case Series
  M Hussaini, H Shao, P Horna, M Markow, Am J Clin Pathol, 1/1/2015
• Evolution of Chronic Lymphocytic Leukemia to Atypical Burkitt Lymphoma
  A Rehman, P Horna, M Hussaini, International Clinical Cytometry Society 2014 Annual Meeting, Seattle, WA, 1/1/2014
• CD4+ Diffuse Large B-cell lymphomas: an aggressive subtype
  Hussaini M, A Hassan, TT Nguyen, F Kreisel, J Frater, Modern Pathology, 1/1/2013
• DNA Mechanisms of FLT3 Internal Tandem Duplications in Acute Myeloid Leukemia
  Hussaini M, E Duncavage, Modern Pathology, 1/1/2013
• Performance of Next-Generation Sequencing for Detection of Clinically Actionable Genetic Variants in Cancer
  Hussaini M, Hagemann IS, Cox TM, Lockwood T, Seibert K, Kulkarni S, Pfeifer JD, Duncavage E, American Society of Clinical Oncology Annual Meeting, Chicago, 1/1/2013
• Detection of Epstein Barr Virus in Lymphoma by Multiplex Targeted Next Generation Sequencing
  Chastain E, Hussaini M, Pfeifer E, Abel H, Duncavage E, Journal of Molecular Diagnostics, Association of Molecular Pathology Annual Meeting, 1/1/2013
• Spectrum of Actionable Variants Identified by Clinical Targeted Next-Generation Sequencing in Cancer
  H. Al-Kateb, I. Hageman, C.E. Cottrell, C. Lockwood, T. Nguyen, E.J. Duncavage, D. Spencer, A. Bredemeyer, T. Cox, M. Hussaini, R. Head, S. Shrivastava, R. Nagarajan, ..., Journal of Molecular Diagnostics, Association of Molecular Pathology Annual Meeting, 1/1/2013
• Prognostic value of 1p36 and p16 deletions in diffuse large B-cell lymphoma in predicting response to R-CHOP
  Hussaini M i, A Gru, AF Cashen, JL Frater, A Hassan, TT Nguyen, F Kreisel, Archives of Pathology and Laboratory Medicine, 1/1/2011
• Utility of PRDM1 in Differentiation of Marginal Zone and Lymphoplasmacytic Lymphoma
  Hussaini M, C Yeung, A Hassan, Modern Pathology, 1/1/2011
• Predictive values of proliferative indices in marginal zone lymphomas
  Hussaini M, F Kreisel, A Hassan, American Society of Clinical Pathology Annual Meeting, 1/1/2010
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Lectures

• Moffitt Cancer Center 2-Year Single-Institution Experience with Next-Generation Sequencing Minimal Residual Disease Detection: Clinical Utility, Application, and Corre... 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Increased Frequency of IDH1/2 Mutations in Extramedullary Acute Myeloid Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Clonal Suppression of TP53 Mutant MDS and Oligoblastic AML with Hypomethylating Agent Therapy Improves Overall Survival 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Role of Next Generation Sequencing in Lymphoid Malignancies 
  1/1/2017
• Religion and Medicine 
  1/1/2016
• Next Generation Sequencing in Diagnostics and Research in the Context of Hematological Malignancies 
  Riyadh, Saudi Arabia - 1/1/2015
• Clinical Scenarios in MDS 2015-Diagnostic Pathways and Pitfalls 
  Riyadh, Saudi Arabia - 1/1/2015
• Acute Lymphoblastic Leukemia- Review and Update 
  Qassim, Saudi Arabia - 1/1/2015
• CML: How Low Do We Go? 
  Makkah, Saudi Arabia - 1/1/2015
• Next Generation sequencing and Laboratory Medicine 
  King Faisal Specialist and Research Hospital - 1/1/2015
• Review of Molecular Biomarkers in Myeloid Disease 
  King Faisal Specialist and Research Hospital - 1/1/2015
• Spiritual Diversity in Medicine 
  USF Medical School - 1/1/2014
• Off the beaten path: what they don't teach you in medical school 
  USF Medical School - 1/1/2013
• Step 1 Strategies and Spirituality 
  USF Medical School - 1/1/2013
• Institution of Hematologic Malignancy Algorithm Decreases Molecular Diagnostic Lab Utilization in Acute Myeloid Leukemia Testing 
  Emory University - 1/1/2013
• Introduction to Next Generation Sequencing: Clinical and Research applications 
  1/11/2017
• Next Generation Sequencing in Lymphoid Malignancies 
  1/11/2016
• Breast and GI tract Lymphomas 
  1/26/2016
• Step1 and Spirituality 
  1/26/2016
• Tips on making it Through Medical School 
  USF Medical School - 1/29/2014
• Hematologic Neoplasms Involving Breast/ Gastrointestinal Tract 
  Hilton Clearwater Beach, Clearwater, FL - 1/26/2015
• Next Generation Sequencing: What the Pathologist Needs to Know 
  1/18/2016
• Clinical Implications of Next Generation Sequencing 
  Moffitt Cancer Center - 1/17/2016
• Personalized Medicine at the Moffitt Cancer Center 
  1/9./2016
• CLL Diagnosis, Prognostic Factors, Genomics and MRD Detection 
  Embassy Suites, Tampa, FL - 1/16/2017
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