MoniqueEvangelineHinchcliffMDMS

PubMed

• 1 citations
  Gene expression meta-analysis reveals aging and cellular senescence signatures in scleroderma-associated interstitial lung disease.
  Monica M Yang, Seoyeon Lee, Jessica Neely, Monique Hinchcliff, Paul J Wolters, Marina Sirota> ;Frontiers in Immunology. 2024 Jan 1
• IL-6 trans-signaling in a humanized mouse model of scleroderma.
  Ian D Odell, Kriti Agrawal, Esen Sefik, Anahi V Odell, Elizabeth Caves, Nancy C Kirkiles-Smith, Valerie Horsley, Monique Hinchcliff, Jordan S Pober, Yuval Kluger, Rich...> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Sep 12
• Correction: Learnings from clinical trials in patients with connective tissue disease‑associated interstitial lung disease.
  Jean Paul Higuero Sevilla, Areeka Memon, Monique Hinchcliff> ;Arthritis Research & Therapy. 2023 Jul 27
• 1 citations
  Learnings from clinical trials in patients with connective tissue disease-associated interstitial lung disease.
  Jean Paul Higuero Sevilla, Areeka Memon, Monique Hinchcliff> ;Arthritis Research & Therapy. 2023 Jul 8
• 2 citations
  Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis.
  Attila Feher, Edward J Miller, Dana C Peters, Hamid R Mojibian, Albert J Sinusas, Monique Hinchcliff, Lauren A Baldassarre> ;Rheumatology International. 2023 May 1
• Hyperspectral imaging in systemic sclerosis-associated Raynaud phenomenon.
  Shannon Teaw, Akash Gupta, Alyssa Williams, F Perry Wilson, Brandon J Sumpio, Bauer E Sumpio, Monique Hinchcliff> ;Arthritis Research & Therapy. 2023 Jan 20
• 8 citations
  Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis.
  Ian D Odell, Holly Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell> ;Science Immunology. 2022 Dec 16
• 3 citations
  Three Distinct Transcriptional Profiles of Monocytes Associate with Disease Activity in Scleroderma Patients.
  Hadijat-Kubura M Makinde, Julia L M Dunn, Gaurav Gadhvi, Mary Carns, Kathleen Aren, Anh H Chung, Lutfiyya N Muhammad, Jing Song, Carla M Cuda, Salina Dominguez, John E...> ;Arthritis & Rheumatology. 2023 Apr 1
• A Novel MIP-1-Expressing Macrophage Subtype in BAL Fluid from Healthy Volunteers.
  Paul A Reyfman, Elizabeth S Malsin, Basil Khuder, Nikita Joshi, Gaurav Gadhvi, Annette S Flozak, Mary A Carns, Kathleen Aren, Isaac A Goldberg, Seokjo Kim, Michael Ale...> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Feb 1
• 6 citations
  Clinical Phenotypes of Patients With Systemic Sclerosis With Distinct Molecular Signatures in Skin.
  Monica Yang, Vivien Goh, Jungwha Lee, Monica Espinoza, Yiwei Yuan, Mary Carns, Kathleen Aren, Lorinda Chung, Dinesh Khanna, Zsuzsanna H McMahan, Rishi Agrawal, Lauren ...> ;Arthritis Care & Research. 2023 Jul 1
• 5 citations
  Human dermal fibroblast-derived exosomes induce macrophage activation in systemic sclerosis.
  Rajan Bhandari, Heetaek Yang, Noelle N Kosarek, Avi E Smith, Jonathan A Garlick, Monique Hinchcliff, Michael L Whitfield, Patricia A Pioli> ;Rheumatology. 2023 Feb 6
• 1 citations
  Differences in symptom experience among patients with systemic sclerosis: a cluster analytic approach to identifying subgroups.
  Susan L Murphy, Yen T Chen, Yvonne C Lee, Mary Carns, Kathleen Aren, Benjamin Korman, Monique Hinchcliff, John Varga> ;Rheumatology. 2023 Feb 6
• 2 citations
  Clinical and Autoantibody Associations in Antinuclear Antibody-Positive Systemic Sclerosis Lacking Prototypic Autoantibodies.
  Karen Kruzer, Roberta Goncalves Marangoni, Ilana Heckler, Aya Elhage, John Varga, Monique Hinchcliff, Mary Carns, Kathleen Aren, Amy Wielgosz, Marc Nuzzo, Iswariya Ven...> ;Journal of Clinical Rheumatology. 2023 Jan 1
• 5 citations
  A genomic meta-analysis of clinical variables and their association with intrinsic molecular subsets in systemic sclerosis.
  Jennifer M Franks, Diana M Toledo, Viktor Martyanov, Yue Wang, Suiyuan Huang, Tammara A Wood, Cathie Spino, Lorinda Chung, Christopher P Denton, Emma Derrett-Smith, Je...> ;Rheumatology. 2022 Dec 23
• 11 citations
  Lung Injury Induces Alveolar Type 2 Cell Hypertrophy and Polyploidy with Implications for Repair and Regeneration.
  Anthea Weng, Mariana Maciel Herrerias, Satoshi Watanabe, Lynn C Welch, Annette S Flozak, Rogan A Grant, Raul Piseaux Aillon, Laura A Dada, Seung Hye Han, Monique Hinch...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 May 1
• 17 citations
  High-throughput identification of autoantibodies that target the human exoproteome.
  Eric Y Wang, Yile Dai, Connor E Rosen, Monica M Schmitt, Mei X Dong, Elise M N Ferré, Feimei Liu, Yi Yang, Jaime A González-Hernández, Eric Meffre, Monique Hinchcliff,...> ;Cell Reports Methods. 2022 Feb 28
• 2 citations
  FDG PET vascular imaging in IgG4-RD: Potential and challenges.
  Darko Pucar, Monique Hinchcliff> ;Journal of Nuclear Cardiology. 2022 Dec 1
• Cellular and Molecular Diversity in Scleroderma.
  Monique Hinchcliff, Rolando Garcia-Milian, Stefano Di Donato, Karin Dill, Elizabeth Bundschuh, Francesco Del Galdo> ;Seminars in Immunology. 2021 Dec 1
• 4 citations
  The Scleroderma Patient-centered Intervention Network Self-Management (SPIN-SELF) Program: protocol for a two-arm parallel partially nested randomized controlled feasi...
  Julia Nordlund, Richard S. Henry, Linda Kwakkenbos, Marie-Eve Carrier, Brooke Levis, Warren R. Nielson, Susan J. Bartlett, Laura Dyas, Lydia Tao, Claire Fedoruk, Karen...> ;Trials. 2021 Nov 27
• 5 citations
  Heterogeneity of primary and secondary peristalsis in systemic sclerosis: A new model of "scleroderma esophagus".
  Dustin A. Carlson, Jacqueline Prescott, Emma Germond, Darren M. Brenner, Mary Carns, Chase Correia, Marie Pier Tetreault, Zsuzsanna H. McMahan, Monique Hinchcliff, Wen...> ;Neurogastroenterology and Motility. 2021 Oct 28
• 6 citations
  Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease.
  Attila Feher, Nabil E. Boutagy, Evangelos Oikonomou, Yi-Hwa Liu, Edward J. Miller, Albert J. Sinusas, Monique Hinchcliff> ;Circulation. Cardiovascular Imaging. 2021 Sep 1
• 2 citations
  Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis.
  Attila Feher, Nabil E. Boutagy, Evangelos Oikonomou, Stephanie Thorn, Yi-Hwa Liu, Edward J. Miller, Albert J. Sinusas, Monique Hinchcliff> ;The Journal of Rheumatology. 2021 Jul 15
• 4 citations
  Esophageal Dilation and Other Clinical Factors Associated With Pulmonary Function Decline in Patients With Systemic Sclerosis.
  Kimberly Showalter, Aileen Hoffmann, Carrie Richardson, David A. Aaby, Jongmin Lee, Jane Dematte, Rishi Agrawal, Hatice Savas, Xiaoping Wu, Rowland W. Chang, Monique H...> ;The Journal of Rheumatology. 2021 Jul 15
• 5 citations
  Circulating CTRP9 is Associated with Severity of Systemic Sclerosis-associated Interstitial Lung Disease.
  Monica M Yang, Lauren C. Balmert, Roberta Goncalves Marangoni, Mary Carns, Monique Hinchcliff, Benjamin D. Korman, John Varga> ;Arthritis Care & Research. 2021 Jul 12
• 20 citations
  Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective m...
  Sara Jaafar, Alain Lescoat, Suiyuan Huang, Jessica K. Gordon, Monique Hinchcliff, Ami A. Shah, Shervin Assassi, Robyn T. Domsic, Elana J. Bernstein, Virginia D. Steen,...> ;Arthritis Research & Therapy. 2021 Jun 14
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Journal Articles

• Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis  
  Miruna Carnaru, MD, and Monique Hinchcliff, MD, MS, Springer Nature, 2/12/2021
• The Scleroderma Patient-Centered Intervention Network Cohort: Baseline Clinical Features and Comparison with Other Large Scleroderma Cohorts  
  Daniel E Furst, Robert Spiera, Maureen D Mayes, Lorinda Chung, Suzanne Kafaja, Virginia Steen, Shervin Assassi, Monique Hinchcliff, Rheumatology
• Mycophenolate mofetil treatment of systemic sclerosis reduces myeloid cell numbers and attenuates the inflammatory gene signature in skin Journal of Investigative Derm...  
  Hinchcliff M, Toledo DM, Taroni JN, Wood TA, Franks JM, Ball MS, Hoffmann A, Amin SA, Tan AU, Tom K, Nesbeth Y, Lee J, Ma M, Aren K, Carns MA, Pioli PA, Whitfield ML, J Invest Dermatol, 1/31/2018
• Validation of the Brief Fear of Negative Evaluation Scale-II in patients with systemic sclerosis: A Scleroderma Patient-centered Intervention Network Cohort study  
  Fox RS, Kwakkenbos L, Carrier ME, Mills SD, Gholizadeh S, Jewett LR, Roesch SC, Merz EL, Assassi S, Furst DE, Gottesman K, Mayes MD, Thombs BD, Malcarne VL; SPIN Inves..., Arthritis Care Res (Hoboken), 1/6/2018
• Reliability and Validity of the Tender and Swollen Joint Counts and Modified Rodnan Skin Score in Early Diffuse Cutaneous Systemic Sclerosis  
  Gordon JK, Girish G, Berrocal VJ, Zhang M, Hatzis C, Assassi S, Bernstein EJ, Domsic RT, Hant F, Hinchcliff M, Schiopu E, Steen VD, Frech T, Khanna D, J Rheumatol, 1/15/2017
• Abnormal esophageal acid exposure on high-dose proton pump inhibitor therapy is common in systemic sclerosis patients  
  Stern EK, Carlson DA, Falmagne S, Hoffmann A, Carns MA, Pandolfino JE, Hinchcliff M, Brenner DM, Neurogastroenterology and Motility, 1/6/2017
• Contributed equally Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the lifespan  
  Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen C, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M,..., J Exp Med, 1/1/2017
• A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis, pulmonary fibrosis and pulmonary arterial hypertension  
  Taroni JN, Greene CS, Martyanov V, Wood TA, Christmann RB; Farber HW, Lafyatis RA, Denton CP, Hinchcliff ME, Pioli PA, Mahoney JM, Whitfield ML, Genome Med, 1/1/2017
• The association between systemic sclerosis disease manifestations and esophageal high-resolution manometry parameters  
  Kimmel JN, Carlson DA, Hinchcliff M, Carns MA, Aren KA, Lee J, Pandolfino JE, Neurogastroenterol Motil, 1/27/2016
• Esophageal dilatation and interstitial lung disease in systemic sclerosis: A cross-sectional study  
  Richardson C, Agrawal R, Lee J, Almagor O, Nelson R, Varga J, Cuttica MJ, Dematte JD, Chang RW, Hinchcliff ME, Semin Arthritis Rheum, 1/26/2016
• Integrated, Multi-cohort Analysis of Systemic Sclerosis Identifies Robust Transcriptional Signature of Disease Severity  
  Lofgren S, Hinchcliff M, Carns M, Wood TA, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi A, Boin F, Chung L, Fiore..., Journal of Clinical Investigation Insight, 1/22/2016
• Loss of Peristaltic Reserve, Determined by Multiple Rapid Swallows is the Most Frequent Esophageal Motility Abnormality in Patients with Systemic Sclerosis  
  Carlson DA, Crowell MD, Kimmel JN, Patel A, Gyawali CP, Hinchcliff M, Griffing WL, Pandolfino JE, Vela MF, Clin Gastroenterol Hepatol, 1/5/2016
• Calcinosis is associated with digital ulcers and osteoporosis in patients with Systemic Sclerosis: A Scleroderma Clinical Trials Consortium Study  
  Valenzuela A, Gordon J, Rodriguez-Reyna TS, Proudman S, Hsu V, Baron M, Medsger TA, Assassi S, Salazar G, Hinchcliff M, Fiorentino D, Khanna D, Young A, Kahaleh B, Cas..., Semin Arthritis Rheum, 1/2/2016
• Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients  
  Wu M, Assassi S, Salazar GA, Pedroza C, Gorlova OY, Chen WV, Charles J, Taing ML, Liao K, Wigley FM, Hummers LK, Shah AA, Hinchcliff M, Khanna D, Schiopu E, Phillips K..., Arthritis Res Ther, 1/1/2016
• Tenascin-C drives persistence of organ fibrosis  
  Bhattacharyya S, Wang W, Morales-Nebreda L, Feng G, Wu M, Zhou X, Lafyatis R, Lee J, Hinchcliff M, Feghali-Bostwick C, Lakota K, Budinger GR, Raparia K, Tamaki Z, Varga J, Nat Commun, 1/1/2016
• Controversies: molecular vs clinical systemic sclerosis classification  
  Johnson SR, Hinchcliff M, Asano Y, J scleroderma Relat Disord, 1/1/2016
• Survival in SSc-PAH by Serum Autoantibody Status in the Pulmonary Hypertension Assessment and Recognition of Outcomes Registry  
  Hinchcliff ME, Khanna S, Lee J, Podlusky S, Almagor O, Chang RW, Steen VD, Chung L for the PHAROS Investigators, Seminars in Arthritis and Rheumatism, 1/19/2015
• Association between Initial Oral Therapy and Outcomes in Systemic Sclerosis-related Pulmonary Arterial Hypertension: Observations from PHAROS  
  Lammi MR, Mathai SC, Saketkoo L, Domsic RT, Bojanowski C, Furst D, Steen V; PHAROS Investigators: Hinchcliff M, Varga J, Frech T, Hummers L, Hsu V, Chung L, Csuka ME, ..., Arthritis Rheumatol, 1/19/2015
• Longitudinal evaluation of PROMIS-29 and FACIT-Dyspnea short forms in systemic sclerosis  
  Hinchcliff M, Beaumont JL, Carns M, Podlusky S, Thavarajah K, Varga J, Cella D, Chang RW, J Rheumatol, 1/1/2015
• Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms  
  Mahoney JM, Taroni J, Martyanov V, Wood TA, Greene CS, Pioli PA, Hinchcliff ME, Whitfield ML, PLoS Comput Biol, 1/1/2015
• Serum amyloid A is a marker for pulmonary involvement in systemic sclerosis  
  Lakota K, Carns M, Podlusky S, Mrak-Poljsak K, Hinchcliff M, Lee J, Tomsic M, Sodin-Semrl S, Varga J, PLoS One, 1/1/2015
• Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: a case report  
  Frech TM, Revelo MP, Ryan JJ, Shah AA, Gordon J, Domsic R, Hant F, Assassi S, Shanmugam VK, Hinchcliff M, Steen V, Khanna D, Bernstein EJ, Cox J, Luem N, Drakos S, J Med Case Rep, 1/1/2015
• A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-y) gene and systemic sclerosis  
  Marangoni RG, Korman BD, Allanore Y, Dieude P, Armstrong LL, Rzhetskaya M, Hinchcliff M, Carns M, Podlusky S, Shah SJ, Ruiz B, Hachulla E, Tiev K, Cracowski JL, Varga ..., Arthritis Res Ther, 1/1/2015
• The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor B Signaling  
  Wei J, Ghosh AK, Chu H, Fang F, Hinchcliff ME, Wang J, Marangoni RG, Varga J, Arthritis Rheumatol, 1/1/2015
• Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures  
  Taroni JN, Martyanov V, Huang CC, Mahoney JM, Hirano I, Shetuni B, Yang GY, Brenner D, Jung B, Wood TA, Bhattacharyya S, Almagor O, Lee J, Sirajuddin A, Varga J, Chang..., Arthritis Research & Therapy, 1/1/2015
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Books/Book Chapters

• Scleroderma: From Pathogenesis to Comprehensive Management 
  Chapter: Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis. 
  Hinchcliff M, Whitfield MEdition 2nd,2016
• Scleroderma: From Pathogenesis to Comprehensive Management. 
  Chapter: Generic Patient �Reported Outcome Instruments In Systemic Sclerosis: Patient-Reported Outcomes Information System (PROMIS) and Functional Assessment of Chronic Illness Therapy (FACIT). 
  Hinchcliff M, Cella DEditors: Varga J, Denton C, Wigley F.2012

Abstracts/Posters

• High-throughput Quantitative Histology in Systemic Sclerosis Skin Disease Using Computer Vision.
  Correia C, Saber R, Hoffmann A, Wood TA, Whitfield ML, Hinchcliff M, Mahoney JM, Scleroderma World Congress, Amsterdam, Netherlands, 1/1/2018
• Optimal forced vital capacity and lung diffusion cut-points for associated interstitial lung disease in systemic sclerosis.
  Showalter K, Hoffmann A, Aaby D, Richardson C, Dematte J, Chang RW, Rishi Agrawal R, Lee J, Hinchcliff M, American College of Physicians Residents' and Medical Students' Day, Chicago, IL, 1/9/2016

Lectures

• New Clinical and Research Developments in Systemic Sclerosis 
  Bridgeport Hospital, 2019, Griffin Hospital, 2019 - 1/7/2019
• Academia with a Focus on Research and Work/Life Balance. 
  American College of Rheumatology, Chicago, IL, 2016, 2018 - 1/13/2018
• Translational Research in Systemic Sclerosis. 
  Yale School of Medicine Rheumatology, New Haven, CT - 1/29/2017
• The modified Rodnan skin score. 
  American College of Rheumatology, Chicago, IL - 1/28/2017
• Clinical and research update in systemic sclerosis. 
  Presence St. Joseph Hospital, Chicago, IL - 1/26/2017
• Starting a Career in Translational Research. 
  San Diego, CA - 1/3/2017
• Rheumatology Update for the Primary Care Physician. 
  Rosemont, IL - 1/15/2016
• The Scleroderma Esophagus. 
  Cleveland, OH, 2015; New York University Langone Medical Center, New York, NY, 2015 - 1/12/2015
• Scleroderma. 
  Fontana, WI - 1/31/2014
• SSc intrinsic subset classification in patients that demonstrate clinical improvement during treatment. 
  Boston, MA, 2013; Rome, Italy, 2014 - 1/5/2014
• Essential Role for Alternately-Spliced Tenascin-C and TLR4 in Persistence of Organ Fibrosis. 
  Boston, MA - 1/1/2014
• Novel High-throughput Biomarkers in SSc. 
  San Francisco, CA - 1/23/2013
• Systemic Sclerosis: A Treatable Multi-System Disease. 
  Chicago, IL - 1/22/2013
• The utility of measuring gene expression in skin as a biomarker of systemic sclerosis. 
  Geisel School of Medicine at Dartmouth Medical Center, Hanover, NH, 2012; University of Utah, Salt L - 1/15/2013
• Gene Expression in SSc skin and esophagus provides insights into pathogenesis. 
  University of Alabama Birmingham, Birmingham, AL - 1/7/2013
• Autologous Stem Cell Transplant Outcomes in Systemic Sclerosis: The Northwestern Scleroderma Program experience. 
  Montereggioni, Italy - 1/4/2013
• Gene Expression in Skin: Biomarker Studies. 
  Stanford University, Stanford, CA - 1/23/2012
• Pathogenesis and Treatment of Systemic Sclerosis. 
  Mt. Sinai Hospital, Chicago, IL - 1/15/2012
• Crystalline Arthropathies: other crystals that cause joint pain in addition to gout. 
  Rehabilitation Institute of Chicago Academy, Chicago, IL - 1/28/2011
• The Genetics of Systemic Scleroderma. 
  Chicago, IL - 1/24/2011
• Assessing gene expression before and after mycophenolate mofetil (Cellcept) treatment in skin biopsies from patients with scleroderma: the agony and the ecstasy of RNA... 
  Ann Arbor, MI - 1/1/2011
• Navigating the American College of Rheumatology Annual Scientific Meeting. 
  Atlanta, GA - 1/6/2010
• Raynaud's Phenomenon: not just a medley of color. 
  Northwestern University Feinberg School of Medicine - 1/26/2009
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Other

• Contributed equally. Integrative Cardiac Phenomapping and Skin Genome Expression Analysis Identify Similarities in Pathophysiology in Systemic Sclerosis 
  Hinchcliff M, Frech T, Wood TA, Huang CC, Ryan JJ, Beussink-Nelson L, Ma M, Julia Lee J, Varga J, Chang RW, Whitfield ML, Deo RC, Shah SJ
  https://www.biorxiv.org/content/early/2017/11/03/213678
  1/1/2017