MorganLocyMD

PubMed

• 14 citations
  Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice.
  Mary E. Robbins, Hye Youn Cho, Jason M. Hansen, Joseph R. Luchsinger, Morgan L. Locy, Markus Velten, Steven R. Kleeberger, Lynette K. Rogers, Trent E. Tipple> ;Redox Biology. 2021 Jan 1
• 9 citations
  Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration
  Morgan L. Locy, Sunad Rangarajan, Sufen Yang, Mark R. Johnson, Karen Bernard, Ashish Kurundkar, Nathaniel B. Bone, Jaroslaw W. Zmijewski, Jaeman Byun, Subramaniam Penn...> ;Science Signaling. 2020 Aug 11
• 25 citations
  Reversing Mechanoinductive DSP Expression by CRISPR/dCas9–mediated Epigenome Editing
  Jing Qu, Lanyan Zhu, Zijing Zhou, Ping Chen, Shuyan Liu, Morgan L. Locy, Victor J. Thannickal, Yong Zhou> ;American Journal of Respiratory and Critical Care Medicine. 2018 Aug 31
• 27 citations
  Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis.
  Jarrod W. Barnes, Dawn Duncan, Scott Helton, Samuel B. Hutcheson, Deepali Kurundkar, Naomi J. Logsdon, Morgan L. Locy, Jaleesa M. Garth, R. Denson, Carol Farver, Hai T...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2019 May 1
• 61 citations
  Fibronectin on the Surface of Extracellular Vesicles Mediates Fibroblast Invasion.
  Diptiman Chanda, Eva Otoupalova, Kenneth P. Hough, Morgan L. Locy, Karen Bernard, Jessy S. Deshane, Ralph D. Sanderson, James A. Mobley, Victor J. Thannickal> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Mar 1
• 28 citations
  The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanisms
  Katelyn Dunigan, Qian Li, Rui Li, Morgan L. Locy, Stephanie B. Wall, Trent E. Tipple> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2018 Oct 1
• 9 citations
  Author Correction: Metformin reverses established lung fibrosis in a bleomycin model.
  Sunad Rangarajan, Nathaniel B. Bone, Anna A. Zmijewska, Shaoning Jiang, Dae Won Park, Karen Bernard, Morgan L. Locy, Saranya Ravi, Jessy S. Deshane, Roslyn B. Mannon, ...> ;Nature Medicine. 2018 Oct 1
• 338 citations
  Metformin reverses established lung fibrosis in a bleomycin model.
  Sunad Rangarajan, Nathaniel B. Bone, Anna A. Zmijewska, Shaoning Jiang, Dae Won Park, Karen Bernard, Morgan L. Locy, Saranya Ravi, Jessy S. Deshane, Roslyn B. Mannon, ...> ;Nature Medicine. 2018 Jul 2
• 13 citations
  Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.
  Philip J. O'Reilly, Qiang Ding, Samia Akthar, Guo-Qiang Cai, Kristopher R. Genschmer, Dhiren F. Patel, Patricia L. Jackson, Liliana Viera, Mojtaba Abdul Roda, Morgan L...> ;JCI Insight. 2017 Nov 16
• 42 citations
  Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis.
  Diptiman Chanda, Ashish Kurundkar, Sunad Rangarajan, Morgan L. Locy, Karen Bernard, Nirmal S. Sharma, Naomi J. Logsdon, Hui Liu, David K. Crossman, Jeffrey C. Horowitz...> ;Scientific Reports. 2016 Nov 21
• 44 citations
  Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2–Related Factor 2 Activation
  Qian Li, Stephanie B. Wall, Changchun Ren, Markus Velten, Cynthia L. Hill, Morgan L. Locy, Lynette K. Rogers, Trent E. Tipple> ;American Journal of Respiratory Cell and Molecular Biology. 2016 Sep 1
• 30 citations
  Oxidative Modifications of Protein Tyrosyl Residues Are Increased in Plasma of Human Subjects with Interstitial Lung Disease.
  Subramaniam Pennathur, Anuradha Vivekanandan-Giri, Morgan L. Locy, Tejaswini Kulkarni, Degui Zhi, Lixia Zeng, Jaeman Byun, Joao A. de Andrade, Victor J. Thannickal> ;American Journal of Respiratory and Critical Care Medicine. 2016 Apr 15
• 55 citations
  The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.
  Ashish Kurundkar, Deepali Kurundkar, Sunad Rangarajan, Morgan L. Locy, Yong Zhou, Rui-Ming Liu, Jaroslaw W. Zmijewski, Victor J. Thannickal> ;FASEB Journal. 2016 Feb 16
• 13 citations
  Modification of Platelet Proteins by 4-hydroxynonenal: Potential Mechanisms for Inhibition of Aggregation and Metabolism
  Saranya Ravi, Michelle S. Johnson, Balu K. Chacko, Philip A. Kramer, Hirotaka Sawada, Morgan L. Locy, Landon Wilson, Stephen Barnes, Marisa B. Marques, Victor M. Darle...> ;Free Radical Biology & Medicine. 2016 Feb 1
• 43 citations
  Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?
  Sunad Rangarajan, Morgan L. Locy, Tracy Luckhardt, Victor J. Thannickal> ;Drugs. 2016 Jan 4
• 32 citations
  The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome.
  Rodney D. Britt, Markus Velten, Morgan L. Locy, Lynette K. Rogers, Trent E. Tipple> ;Antioxidants & Redox Signaling. 2014 Jun 10
• 12 citations
  Neonatal hyperoxic exposure persistently alters lung secretoglobins and annexin A1.
  Thomas M. Raffay, Morgan L. Locy, Cynthia L. Hill, Nik S. Jindal, Lynette K. Rogers, Stephen E. Welty, Trent E. Tipple> ;Biomed Research International. 2013 Sep 26
• 25 citations
  Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation.
  Bernadette Chen, Viktoria Nelin, Morgan L. Locy, Yi Jin, Trent E. Tipple> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2013 Sep 1
• 45 citations
  Thioredoxin reductase inhibition elicits Nrf2-mediated responses in Clara cells: implications for oxidant-induced lung injury.
  Morgan L. Locy, Lynette K. Rogers, Justin R. Prigge, Edward E. Schmidt, Elias S.J. Arnér, Trent E. Tipple> ;Antioxidants & Redox Signaling. 2012 Nov 15
• 17 citations
  Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed Clara cells.
  Rodney D. Britt, Morgan L. Locy, Trent E. Tipple, Leif D. Nelin, Lynette K. Rogers> ;Cellular Physiology and Biochemistry. 2012 Jan 1
• Join now to see all

Journal Articles

• Author Correction: Metformin Reverses Established Lung Fibrosis in a Bleomycin Model  
  Morgan L Locy, Roslyn B Mannon, Sunad Rangarajan, Edward Abraham, Nature
• Metformin Reverses Established Lung Fibrosis in a Bleomycin Model  
  Sunad Rangarajan, Morgan L Locy, Edward Abraham, Roslyn B Mannon, Nature