MuhammadAfzalMDMS

PubMed

• Downregulation of homeobox B8 in attenuating non-small cell lung cancer cell migration and invasion though the epithelial-mesenchymal transition pathway.
  Jiang, S., Wang, T., Han, Y., Hida, T., Zhou, C., Zhu, J., Wang, H., Afzal, M.> ;Translational Cancer Research. 2024 Jan 31
• Acute myeloid leukemia cutis with KMT2A::MLLT3 fusion presenting with leonine facies.
  Lansigan, E., Wankel, B., Afzal, M., Loo, E., LeBlanc, R., Carter, J., Yerrabothala, S.> ;Leukemia Research Reports. 2024 Jan 1
• Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Series.
  John P Palmer, Arief A Suriawinata, Shaofeng Yan, Darcy A Kerr, Muhammad Z Afzal, Keisuke Shirai> ;The American Journal of Case Reports. 2023 Nov 18
• Rare immune-related adverse events in a patient with metastatic melanoma: a case report highlighting sarcoidosis-like reactions triggered by immune-checkpoint inhibitors.
  Yuanzhen Cao, Muhammad Zubair Afzal, Keisuke Shirai, Edward J Gutmann> ;Melanoma Research. 2024 Feb 1
• Durable complete response to early immunotherapy discontinuation in a kidney transplant recipient with advanced cutaneous squamous cell carcinoma: A case report and re...
  Ziyao Lu, Muhammad Afzal, Keisuke Shirai> ;Transplant Immunology. 2023 Dec 1
• Clinical presentation of Warburg effect in aggressive lymphoma: a case report.
  Yenong Cao, Margaret C Liu, Emma L Hanlon, York Chen, Muhammad Z Afzal, Christi A Hayes, John M Hill Jr> ;Journal of Medical Case Reports. 2023 Aug 23
• Overexpression ofin predicting poor prognosis and promoting the development of lung adenocarcinoma.
  Dong Wei, Daqiang Sun, Rafael Sirera, Muhammad Zubair Afzal, Tracy L Leong, Xin Li, Yuhang Wang> ;Translational Lung Cancer Research. 2023 Jul 31
• 1 citations
  Complete response of a large basosquamous carcinoma following treatment with cemiplimab and vismodegib.
  Jonathan Pirruccello, Muhammad Zubair Afzal, Keisuke Shirai, Voudouri, M., Mariana Voudouri> ;BMJ Case Reports. 2023 Jul 14
• 1 citations
  Immunotherapy in Anal Cancer.
  Natasha Dhawan, Muhammad Z Afzal, Manik Amin> ;Current Oncology. 2023 Apr 27
• 1 citations
  Ipilimumab and nivolumab induced immune-related adverse events in metastatic mucosal melanoma.
  Yenong Cao, Muhammad Zubair Afzal, Keisuke Shirai> ;BMJ Case Reports. 2021 Aug 20
• 7 citations
  Does denosumab offer survival benefits? -Our experience with denosumab in metastatic non-small cell lung cancer patients treated with immune-checkpoint inhibitors.
  Yenong Cao, Muhammad Zubair Afzal, Keisuke Shirai> ;Journal of Thoracic Disease. 2021 Aug 1
• 26 citations
  Neoadjuvant programmed cell death protein 1 inhibitors combined with chemotherapy in resectable non-small cell lung cancer: an open-label, multicenter, single-arm study.
  Hongtao Duan, Tianhu Wang, Zhilin Luo, Liping Tong, Xiaoping Dong, Yong Zhang, Muhammad Zubair Afzal, Pierpaolo Correale, Honggang Liu, Tao Jiang, Xiaolong Yan> ;Translational Lung Cancer Research. 2021 Feb 1
• 10 citations
  Prognostic Significance of Hematological Indices in Malignant Melanoma Treated With Immune Checkpoint Inhibitors.
  Muhammad Zubair Afzal, Keisuke Shirai, Tayyaba Sarwar> ;Journal of Immunotherapy. 2019 Sep 1
• 82 citations
  The association of PD-L1 expression with the efficacy of anti-PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis of randomiz...
  Yangyang Xu, Bing Wan, Xi Chen, Ping Zhan, Yuan Zhao, Tianli Zhang, Hongbing Liu, Muhammad Zubair Afzal, Said Dermime, Steven N. Hochwald, Paul Hofman, Hossein Borghae...> ;Translational Lung Cancer Research. 2019 Aug 1
• 50 citations
  Clinical outcomes in non-small-cell lung cancer patients receiving concurrent metformin and immune checkpoint inhibitors.
  Muhammad Zubair Afzal, Konstantin H. Dragnev, Keisuke Shirai, Tayyaba Sarwar> ;Lung Cancer Management. 2019 May 7
• 5 citations
  An extended overall survival analysis of pemetrexed and carboplatin with or without pembrolizumab as first-line therapy for advanced non-squamous non-small cell lung c...
  Muhammad Zubair Afzal, Konstantin H. Dragnev, Keisuke Shirai> ;Annals of Translational Medicine. 2019 Nov 3
• 4 citations
  Response to the Rechallenge With Talimogene Laherparepvec (T-VEC) After Ipilimumab/Nivolumab Treatment in Patient With Cutaneous Malignant Melanoma Who Initially Had a...
  Muhammad Zubair Afzal, Keisuke Shirai> ;Journal of Immunotherapy. 2019 Feb 9
• 23 citations
  Immune checkpoint inhibitor (anti-CTLA-4, anti-PD-1) therapy alone versus immune checkpoint inhibitor (anti-CTLA-4, anti-PD-1) therapy in combination with anti-RANKL d...
  Muhammad Zubair Afzal, Keisuke Shirai> ;Melanoma Research. 2018 Aug 1
• 110 citations
  Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma
  Muhammad Zubair Afzal, Rima R. Mercado, Keisuke Shirai> ;Journal for Immunotherapy of Cancer. 2018 Jul 2
• 23 citations
  A tertiary care cancer center experience with carboplatin and pemetrexed in combination with pembrolizumab in comparison with carboplatin and pemetrexed alone in non-s...
  Muhammad Zubair Afzal, Konstantin H. Dragnev, Keisuke Shirai> ;Journal of Thoracic Disease. 2018 Jun 1
• 25 citations
  Metastatic uveal melanoma showing durable response to anti-CTLA-4 and anti-PD-1 combination therapy after experiencing progression on anti-PD-1 therapy alone.
  Muhammad Zubair Afzal, Rodwell Mabaera, Keisuke Shirai> ;Journal for Immunotherapy of Cancer. 2018 Feb 12
• 1 citations
  A retrospective analysis of tolerance and outcomes of cutaneous malignant melanoma in patients receiving adjuvant interferon-alpha 2B: a community oncology perspective.
  Muhammad Zubair Afzal, Vani Pinnamaneni, K C Birendra, Alan T. Davis, Tracy J. Koehler, Nehal Lakhani> ;Journal of Experimental Therapeutics & Oncology. 2017 Sep 1
• 9 citations
  Modification of Technique for Suprapubic Catheter Placement After Robot-assisted Radical Prostatectomy Reduces Catheter-associated Complications
  Muhammad Zubair Afzal, Conrad M. Tobert, Emi Bulica, Sabrina L. Noyes, Brian R. Lane> ;Urology. 2015 Aug 1
• 12 citations
  Spontaneous Regression of Refractory Diffuse Large B-Cell Lymphoma with Improvement in Immune Status with ART in a Patient with HIV: A Case Report and Literature Review.
  K C Birendra, Muhammad Zubair Afzal, Katherine A. Wentland, Hamza Hashmi, Sudhir Singh, Elena Ivan, Nehal Lakhani> ;The American Journal of Case Reports. 2015 Jun 5
• 4 citations
  Utility of Lower Extremity Doppler in Patients with Lower Extremity Cellulitis: A Need to Change the Practice?
  Muhammad Zubair Afzal, Mian Muhammad Saleh, Syed Razvi, Hamza Hashmi, Russell J Lampen> ;Southern Medical Journal. 2015 Mar 10
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Journal Articles

• Metastatic Uveal Melanoma Showing Complete Remission to Anti-CTLA4 and Anti-PD-1 Combination Therapy after Experiencing Progression on Anti-CTLA4 alone  
  Afzal MZ, Mabaera R, Keisuke S, Journal for ImmunoTherapy of Cancer, 1/1/2018
• Immune Checkpoint Inhibitor (Anti-CTLA-4, Anti-PD-1) Therapy Alone versus Immune Checkpoint Inhibitor (Anti-CTLA-4, Anti-PD-1) Therapy in Combination with Anti-RANKL D...  
  Afzal MZ, Keisuke S, Melanoma Research, 1/1/2018
• An Ingestion of Industrial Strength Hydrogen Peroxide Resulting in Cerebral Embolism and Death  
  Afzal MS, Dar SS, Sarwar T, Afzal MZ, American Journal of Medical Case Reports, 1/1/2017
• A retrospective Analysis of Tolerance and Outcomes of Cutaneous Malignant Melanoma in patients receiving Adjuvant Interferon- alpha 2B: A Community Oncology Perspective  
  Afzal MZ, Pinnamaneni V, Birendra KC, Davis AT, Koehler T, Lakhani N, J Exp Ther Oncol, 1/1/2015
• Neuroendocrine prostate cancer (NEPC) after androgen deprivation therapy (ADT): Clinical characteristics  
  Akhtar N H, Beltran H, Afzal MZ, Ecker C, Nanus DM, Tagawa S T, Journal of Clinical Oncology, 1/1/2012
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Abstracts/Posters

• "Recognizing these signs "Will Save Lives"...Classical features of catastrophic syndrome.
  Hashmi H, Afzal MZ, National ACP Meeting, Boston, MA, 1/1/2015
• Facial Nerve Paralysis- A Rare Manifestation and diagnostic prompt for Underlying Sarcoidosis.
  Hashmi H, Afzal MZ, Emig M, GRMEP Research Day, ACP- Michigan Associate Day, 1/1/2014
• Positron emission tomography- computed tomography (PET- CT) in assessment of neuroendocrine prostate cancer (NEPC).
  Martin R, Fareedy SB, Chalasani SR, Tarlington SL, Belal SL, Afzal MZ, Spratt D, Osborn J, 2014 New England Symposium, 1/1/2014
• Utility of Lower Extremity Doppler in Patients with Lower Extremity Cellulitis: A Need to Change the Practice?
  Afzal MZ, Mian M, Razvi S, Hashmi H, Lampen R, ACP Associate Day, 1/1/2014
• Aplastic Anemia and Paroxysmal nocturnal hemoglobinuria in a patient with Chron's disease.
  Afzal MZ, Syed S, Zulfiqar S, Brett B, ACP-Michigan Chapter Meeting, 1/1/2013
• Refractory Hypokalemia in Paraneoplastic Syndrome.
  Syed S, Afzal MZ, Zulfiqar S, ACP-Michigan Chapter Meeting, 1/1/2013
• A Case of Disseminated Zoster in the Setting of Imuran use and Stable Chronic Lymphocytic Leukemia.
  Zulfiqar S, Syed S, Afzal MZ, ACP-Michigan Chapter Meeting, 1/1/2013
• Hydrogen Peroxide: An Accidental Ingestion.
  Afzal MZ, Khan MH, Shabarang C, Eisenga B, ACP-Michigan Chapter Meeting, 1/1/2013
• Ludwig angina secondary to dental abscess leading to medistinitis.
  Khan MH, Afzal MZ, Afzal MS, Lampen R, ACP-Michigan Chapter Meeting, 1/1/2013
• Elevated markers of hemostasis, fibrinolysis and angiogenesis in patients with advance prostate cancer decrease following hormonal therapy in responding patients.
  Arnason JE, Akhtar NH, Afzal MZ, Saran A, Nanus DM, Tagawa, ST, 6th International Conference of Thrombosis and Hemostasis in Cancer, Italy, 1/1/2012
• A 48- year- old woman with 10 days of progressive, painful, ulcerating skin lesions.
  Afzal MZ, ACP-Michigan Chapter Meeting, 1/1/2012
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Lectures

• "Recognizing these signs "Will Save Lives"...Classical features of catastrophic syndrome. 
  Gay Lord, MI - 1/1/2014
• Sty? A rare presentation of Gastric MALT Lymphoma. 
  1/1/2013

Other

• Recognizing these signs will save lives': Classical Features of a Catastrophic Syndrome. 
  Hashmi H, Afzal MZ
  1/1/2015