MyungHeeParkMD

Cardiology • Tacoma, WA

Adult Congenital Heart Disease, Heart Failure & Transplantation, Interventional Cardiology

Division Chief, Heart Failure

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Office
1802 Yakima Ave
Ste 302
Tacoma, WA 98405
Phone+1 253-627-1244

Fax+1 253-627-6576
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Education & Training

Virginia Commonwealth University Health SystemFellowship, Cardiovascular Disease, 1994 - 1997
Temple University HospitalResidency, Internal Medicine, 1991 - 1994
Lewis Katz School of Medicine at Temple UniversityClass of 1991

Certifications & Licensure

WA State Medical License 2019 - 2023
TX State Medical License 2015 - 2020
MD State Medical License 2005 - 2015
LA State Medical License 1998 - 2006
PA State Medical License 1993 - 1994
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Fellow (FACC) American College of Cardiology

Clinical Trials

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) Start of enrollment: 2006 May 01
Completed
Phase 4
The "Power 15 Study": Safety Study of Inhalation of Ventavis With the Power Disc-15 Setting Start of enrollment: 2006 Sep 01
Terminated
Phase 2
Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program Start of enrollment: 2011 Jun 01
Completed
An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension Start of enrollment: 2013 Sep 11
Completed
Phase 3
Targeting the Right Ventricle in Pulmonary Hypertension Start of enrollment: 2013 Jul 01
Completed
Phase 4
Beraprost-314d Added-on to Tyvaso® (BEAT) Start of enrollment: 2013 May 31
Completed
Phase 3
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Publications & Presentations

PubMed

3 citations
The United States Chronic Thromboembolic Pulmonary Hypertension Registry: Protocol for a Prospective, Longitudinal Study.
Kim M. Kerr, C. Greg Elliott, Raymond L. Benza, Richard N. Channick, Kelly Chin, R. Duane Davis, Sonia Jain, Andrea Z. LaCroix, Michael M. Madani, Vallerie V. McLaughl...> ;JMIR Research Protocols. 2021 May 25
7 citations
Elevated Pulmonary Pressure Noted on Echocardiogram: A Simplified Approach to Next Steps
Manreet Kanwar, Ryan J. Tedford, Thenappan Thenappan, Teresa De Marco, Myung H. Park, Vallerie V. McLaughlin> ;Journal of the American Heart Association. 2021 Apr 6
22 citations
Ranolazine Improves Right Ventricular Function in Patients With Precapillary Pulmonary Hypertension: Results From a Double-Blind, Randomized, Placebo-Controlled Trial
Yuchi Han, Paul R. Forfia, Anjali Vaidya, Jeremy A. Mazurek, Myung H. Park, Gautam V. Ramani, Stephen Y. Chan, Aaron B. Waxman> ;Journal of Cardiac Failure. 2021 Feb 1
69 citations
Combination therapy with oral treprostinil for pulmonary arterial hypertension: A double-blind placebo-controlled clinical trial
R. James White, Carlos Jerjes-Sánchez, Gisela Martina Bohns Meyer, Tomas Pulido, Pablo Sepúlveda, Kuo Yang Wang, Ekkehard Grünig, Shirish Hiremath, Zaixin Yu, Gangchen...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Mar 15
1 citations
Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells.
Ashleigh S. Hanner, Matthew Dunworth, Robert A. Casero, Colin W. MacDiarmid, Myung Hee Park> ;The Journal of Biological Chemistry. 2019 Nov 8
12 citations
Delayed autologous stem cell transplantation following cardiac transplantation experience in patients with cardiac amyloidosis.
Barry H. Trachtenberg, Rammurti T. Kamble, Lawrence Rice, Raquel Araujo-Gutierrez, Arvind Bhimaraj, Ashrith Guha, Myung H. Park, I. Hussain, Brian A. Bruckner, Erik E....> ;American Journal of Transplantation. 2019 Oct 1
7 citations
Implication of Ventricular Assist Devices in Extracorporeal Membranous Oxygenation Patients Listed for Heart Transplantation.
Ashrith Guha, Bashar Hannawi, Ana S. Cruz-Solbes, Duc T. Nguyen, Brian A. Bruckner, Barry H. Trachtenberg, Edward A. Graviss, Arvind Bhimaraj, Myung H. Park, I. Hussai...> ;Journal of Clinical Medicine. 2019 Apr 26
32 citations
Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder
Mythily Ganapathi, Leah R. Padgett, Kentaro Yamada, Orrin Devinsky, Rebecca Willaert, Richard E. Person, Ping Yee Billie Au, Julia Tagoe, Marie T. McDonald, Danielle K...> ;American Journal of Human Genetics. 2019 Feb 7
99 citations
Hypusine, a polyamine-derived amino acid critical for eukaryotic translation.
Myung Hee Park, Edith C. Wolff> ;The Journal of Biological Chemistry. 2018 Nov 30
28 citations
Rewiring of cisplatin-resistant bladder cancer cells through epigenetic regulation of genes involved in amino acid metabolism.
Austin Yeon, Sungyong You, Minhyung Kim, Amit Gupta, Myung Hee Park, Daniel J. Weisenberger, Gangning Liang, Jayoung Kim> ;Theranostics. 2018 Aug 10
7 citations
Incidence and outcomes of cancer treatment-related cardiomyopathy among referrals for advanced heart failure
Raquel Araujo-Gutierrez, Sergio H. Ibarra-Cortez, Jerry D. Estep, Arvind Bhimaraj, Ashrith Guha, I. Hussain, Myung H. Park, Guillermo Torre-Amione, Barry H. Trachtenberg> ;Cardio-Oncology. 2018 Mar 20
12 citations
Rationale and design of the ranolazine PH–RV study: a multicentred randomised and placebo-controlled study of ranolazine to improve RV function in patients with non-gr...
Yuchi Han, Paul R. Forfia, Anjali Vaidya, Jeremy A. Mazurek, Myung H. Park, Gautam V. Ramani, Stephen Y. Chan, Aaron B. Waxman> ;Open Heart. 2018 Feb 1
8 citations
Bosentan-based, treat-to-target therapy in patients with pulmonary arterial hypertension: results from the COMPASS-3 study.
Raymond L. Benza, Amresh Raina, Himanshu Gupta, Srinivas Murali, Annie Burden, Michael S. Zastrow, Myung H. Park, Marc A. Simon> ;Pulmonary Circulation. 2018 Jan 19
5 citations
Design of the exercise MRI evaluation of HIV-pulmonary arterial hypertension longitudinal determinants (EXALTED) trial.
Mohamad Amer Alaiti, Aditya Goud, Gautam V. Ramani, Sashwatee Bagchi, Sadeer G. Al-Kindi, Steven Sawicki, Chris T. Longenecker, Trevor Jenkins, David Pauza, Myung H. P...> ;Journal of Cardiovascular Medicine. 2017 Nov 1
7 citations
Melding a high-risk patient for continuous flow left ventricular assist device into a low-risk patient
Javier Amione-Guerra, Ana S. Cruz-Solbes, Hilda Mariana Gonzalez Bonilla, Jerry D. Estep, Ashrith Guha, Arvind Bhimaraj, Erik E. Suarez, Brian A. Bruckner, Guillermo T...> ;ASAIO Journal. 2017 Nov 1
11 citations
Pulmonary Arterial Hypertension in Women
Humna Abid Memon, Myung H. Park> ;Methodist Debakey Cardiovascular Journal. 2017 Oct 1
6 citations
Risk Stratification of Patients With Current Generation Continuous-Flow Left Ventricular Assist Devices Being Bridged to Heart Transplantation
Ashrith Guha, Duc T.M. Nguyen, Ana S. Cruz-Solbes, Javier Amione-Guerra, Robert C. Schutt, Arvind Bhimaraj, Barry H. Trachtenberg, Myung H. Park, Edward A. Graviss, Os...> ;ASAIO Journal. 2017 Sep 11
8 citations
Recommendations for the clinical management of patients receiving macitentan for pulmonary arterial hypertension (PAH): A Delphi consensus document
Franck Rahaghi, Hassan Alnuaimat, Rana Awdish, Vijay Balasubramanian, Robert C. Bourge, Charles D. Burger, John Butler, C. Gregory Cauthen, Murali M. Chakinala, Bennet...> ;Pulmonary Circulation. 2017 Aug 22
6 citations
A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening
Myung Hee Park, Ajeet Mandal, Swati Mandal, Edith C. Wolff> ;Amino Acids. 2017 Aug 17
15 citations
Anemia after continuous-flow left ventricular assist device implantation: characteristics and implications.
Javier Amione-Guerra, Ana S. Cruz-Solbes, Arvind Bhimaraj, Barry H. Trachtenberg, Sai Ravi Pingali, Jerry D. Estep, Myung H. Park, Ashrith Guha> ;The International Journal of Artificial Organs. 2017 Jun 14
Left Heart Disease and Pulmonary Hypertension: Controversy Redefined
Myung H. Park> ;Methodist Debakey Cardiovascular Journal. 2016 Dec 1
Diagnostic and Treatment Advances for Chronic Thromboembolic Pulmonary Hypertension
Alan B. Lumsden, Myung H. Park> ;Methodist Debakey Cardiovascular Journal. 2016 Oct 1
15 citations
Genome‐scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells
Su Xiao, Yu-Chi Chen, Eugene Buehler, Swati Mandal, Ajeet Mandal, Michael J. Betenbaugh, Myung Hee Park, Scott E. Martin, Joseph Shiloach> ;Biotechnology and Bioengineering. 2016 Sep 21
18 citations
Pulmonary Arterial Hypertension: Diagnosis and Treatment
Christopher Barnett, Paulino Alvarez, Myung H. Park> ;Cardiology Clinics. 2016 Aug 1
14 citations
X-ray absorption spectroscopic characterization of the diferric-peroxo intermediate of human deoxyhypusine hydroxylase in the presence of its substrate eIF5a.
Andrew J. Jasniewski, Lisa M. Engstrom, Van V. Vu, Myung Hee Park, Lawrence Que> ;Journal of Biological Inorganic Chemistry. 2016 Jul 5
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Journal Articles

Invasive Hemodynamic After LVAD Implantation and Association with Outcomes
Arvind Bhimaraj, Jerry Estep, Barry Trachtenberg, Myung H Park, Imad Hussain, Journal of Cardiac Failure

Authored Content

Invasive Hemodynamic After LVAD Implantation and Association with OutcomesSeptember 2018

Grant Support

The Post-Translational Synthesis Of Hypusine In Eif5aNational Institute Of Dental &Craniofacial Research2009–2011
The Post-Translational Synthesis Of Hypusine In Eif5aNational Institute Of Dental &Craniofacial Research2002–2008
Oral Carcinogenesis: Studies With Human Gingival KeratinNational Institute Of Dental &Craniofacial Research2004
Oral Carcinogenesis: Human Gingival KeratinocytesNational Institute Of Dental &Craniofacial Research2003
Oral Carcinogenesis: Studies With Human Gingival KerocytNational Institute Of Dental &Craniofacial Research2002
Post Translational Synthesis Of Hypusine In Eif5aNational Institute Of Dental &Craniofacial Research2001
Oral Carcinogenesis--Human Gingival KerocytesNational Institute Of Dental &Craniofacial Research2001
Oral Carcinogenesis: Human Gingival KeratinoocytesNational Institute Of Dental &Craniofacial Research2000
The Post-Translational Synthesis Of Hypusine In Eif5a: Deoxyhypusine SynthaseNational Institute Of Dental &Craniofacial Research1998–2000
Oral Carcinogenesis Studies With Human Gingivial KerocytesNational Institute Of Dental &Craniofacial Research1999
Posttranslational Synthesis Of Hypusine In Eif-5a--Deoxyhypusine SynythaseNational Institute Of Dental &Craniofacial Research1997
Deoxyhypusine Synthase--Purification, Characterization, And CDNA CloningNational Institute Of Dental &Craniofacial Research1994–1996