NaderNajafianMD

PubMed

• Advancing mouse models for transplantation research.
  Cravedi, P., Riella, L., Ford, M., Valujskikh, A., Menon, M., Kirk, A., Alegre, M., Alessandrini, A., Feng, S., Kehn, P., Najafian, N., Hancock, W., Heeger, P., Maltzm...> ;American Journal of Transplantation. 2024 Jan 12
• 10 citations
  Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies.
  Carla Nester, Gerald B Appel, Andrew S Bomback, Koenraad Peter Bouman, H Terence Cook, Erica Daina, Bradley P Dixon, Kara Rice, Nader Najafian, James Hui, Steven D Pod...> ;American Journal of Nephrology. 2022 Jan 1
• 15 citations
  Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms.
  Ciara N. Magee, Naoka Murakami, Thiago J. Borges, Tetsunosuke Shimizu, Kassem Safa, Shunsuke Ohori, Songjie Cai, Audrey Uffing, Jamil Azzi, Wassim Elyaman, Louis-Marie...> ;Circulation. 2019 Sep 3
• 54 citations
  A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection.
  Weijia Zhang, Zhengzi Yi, Karen L. Keung, Huimin Shang, Chengguo Wei, Paolo Cravedi, Zeguo Sun, Caixia Xi, Christopher Woytovich, Samira S. Farouk, Weiqing Huang, Khad...> ;Journal of the American Society of Nephrology. 2019 Jul 5
• 21 citations
  Pretransplant transcriptomic signature in peripheral blood predicts early acute rejection
  Weijia Zhang, Zhengzi Yi, Chengguo Wei, Karen L. Keung, Zeguo Sun, Caixia Xi, Christopher Woytovich, Samira S. Farouk, Lorenzo Gallon, Madhav C. Menon, Ciara N. Magee,...> ;JCI Insight. 2019 Jun 6
• 6 citations
  IL-6 production by monocytes is associated with graft function decline in patients with borderline changes suspicious for acute T-cell-mediated rejection: a pilot study.
  Olivier Désy, Stéphanie Béland, Patrice Vallin, Julie Riopel, Eva Latulippe, Nader Najafian, Anil Chandraker, Mohsen Agharazii, Ibrahim Batal, Sacha A. De Serres> ;Transplant International. 2018 Jan 1
• 4 citations
  Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report
  I.A. Echenique, D. Beltran, L. Ramirez-Ruiz, Nader Najafian, N. Agrawal> ;Transplantation Proceedings. 2017 Sep 1
• 2 citations
  Divergent Function of Programmed Death-Ligand 1 in Donor Tissue versus Recipient Immune System in a Murine Model of Bronchiolitis Obliterans.
  Katharina Schütte-Nütgen, Olaf Boenisch, Hakima Harrach, Alicia Casey, Indira Guleria, Nader Najafian, Mohamed H. Sayegh, Craig Gerard, Meera Subramaniam> ;The American Journal of Pathology. 2017 Jun 1
• 128 citations
  An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria
  Abigail Liebow, Xingsheng Li, Timothy Racie, Julia Hettinger, Brian Bettencourt, Nader Najafian, Patrick Haslett, Kevin Fitzgerald, Ross P. Holmes, David Erbe, William...> ;Journal of the American Society of Nephrology. 2017 Feb 1
• 126 citations
  Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study
  Philip J. O'Connell, Weijia Zhang, Madhav C. Menon, Zhengzi Yi, Bernd Schröppel, Lorenzo Gallon, Y. Luan, Ivy A. Rosales, Yongchao Ge, Bojan Losic, Caixia Xi, Christop...> ;Lancet. 2016 Sep 3
• 27 citations
  Codominant Role of Interferon-γ- and Interleukin-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.
  Thiago J. Borges, John T. O'Malley, Luccie Wo, Naoka Murakami, Brian Smith, Jamil Azzi, Sudipta Tripathi, J. D. Lane, Ericka M. Bueno, Rachael A. Clark, Stefan G. Tull...> ;American Journal of Transplantation. 2016 Apr 7
• 24 citations
  Dendritic Cells in Kidney Transplant Biopsy Samples Are Associated with T Cell Infiltration and Poor Allograft Survival
  Ibrahim Batal, Sacha A. De Serres, Kassem Safa, Vanesa Bijol, Takuya Ueno, Maristela L. Onozato, A. John Iafrate, Jan M. Herter, Andrew H. Lichtman, Tanya N. Mayadas, ...> ;Journal of the American Society of Nephrology. 2015 Apr 8
• 28 citations
  Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus
  Lorenzo Gallon, Opas Traitanon, Nedjema Sustento-Reodica, Joseph R. Leventhal, M. Javeed Ansari, Ricardo C. Gehrau, Venkatesh Kumar Ariyamuthu, Sacha A. De Serres, Ant...> ;Kidney International. 2015 Apr 1
• 65 citations
  TIM-1 signaling is required for maintenance and induction of regulatory B cells
  Melissa Y. Yeung, Qing Ding, Craig R. Brooks, Sheng Xiao, Creg J. Workman, Dario A. A. Vignali, Takuya Ueno, Robert F. Padera, Vijay K. Kuchroo, Nader Najafian, David ...> ;American Journal of Transplantation. 2015 Apr 1
• 31 citations
  Tregitope: Immunomodulation Powerhouse
  Leslie P. Cousens, Nader Najafian, William D. Martin, Anne S. De Groot> ;Human Immunology. 2014 Dec 1
• 32 citations
  Immunophenotyping and Efficacy of Low Dose ATG in Non-Sensitized Kidney Recipients Undergoing Early Steroid Withdrawal: A Randomized Pilot Study
  Monica Grafals, Brian Smith, Naoka Murakami, Agnes Trabucco, Katherine Hamill, Erick Marangos, Hannah Gilligan, Elizabeth A. Pomfret, James J. Pomposelli, Mary Ann Sim...> ;Plos One. 2014 Aug 11
• 39 citations
  Long-term outcomes of kidney transplantation across a positive complement-dependent cytotoxicity crossmatch.
  Leonardo V. Riella, Kassem Safa, Jude Yagan, Belinda T. Lee, Jamil Azzi, Nader Najafian, Reza Abdi, Edgar L. Milford, Helen Mah, Steven Gabardi, Sayeed K. Malek, Stefa...> ;Transplantation. 2014 Jun 27
• 22 citations
  Glomerular inflammation correlates with endothelial injury and with IL-6 and IL-1β secretion in the peripheral blood.
  Ibrahim Batal, Sacha A. De Serres, Bechara Mfarrej, Monica Grafals, Geraldine S. Pinkus, Aarti Kalra, Astrid Weins, Vanesa Bijol, Helmut G. Rennke, Indira Guleria, Rez...> ;Transplantation. 2014 May 27
• 8 citations
  Targeting CD28 to prevent transplant rejection
  Melissa Y. Yeung, Nader Najafian, Mohamed H. Sayegh> ;Expert Opinion on Therapeutic Targets. 2014 Jan 13
• 8 citations
  T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance
  Rozita Abdoli, Nader Najafian> ;International Journal of Organ Transplantation Medicine. 2014 Jan 1
• 25 citations
  Impact of Calcineurin‐Inhibitor Conversion to mTOR Inhibitor on Renal Allograft Function in a Prednisone‐Free Regimen
  Darshika Chhabra, Antonio Alvarado, Pranav Dalal, Joseph R. Leventhal, C. Wang, Nedjema Sustento-Reodica, Nader Najafian, Anton I. Skaro, Josh Levitsky, Valeria R. Mas...> ;American Journal of Transplantation. 2013 Nov 1
• 33 citations
  Interruption of Dendritic Cell–Mediated TIM-4 Signaling Induces Regulatory T Cells and Promotes Skin Allograft Survival
  Melissa Y. Yeung, Martina M. McGrath, Masafumi Nakayama, Tetsunosuke Shimizu, Olaf Boenisch, Ciara N. Magee, Rozita Abdoli, Hisaya Akiba, Takuya Ueno, Laurence A. Turk...> ;Journal of Immunology. 2013 Oct 15
• 145 citations
  Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.
  Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hid...> ;Blood. 2013 Oct 24
• 22 citations
  Jagged2‐signaling promotes IL‐6‐dependent transplant rejection
  Leonardo V. Riella, Jun Yang, Susanne Chock, Kassem Safa, Ciara N. Magee, Vijay K. Vanguri, Wassim Elyaman, Youmna Lahoud, Hideo Yagita, Reza Abdi, Nader Najafian, Jos...> ;European Journal of Immunology. 2013 Jun 1
• 50 citations
  Standardization and Cross Validation of Alloreactive IFNγ ELISPOT Assays Within the Clinical Trials in Organ Transplantation Consortium
  I. Ashoor, Nader Najafian, Y. Korin, Elaine F. Reed, T. Mohanakumar, David Ikle, Peter S. Heeger, Marvin Lin> ;American Journal of Transplantation. 2013 Jul 1
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