NancyChanMD

PubMed

• 1 citations
  A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850.
  Spencer, K., Portal, D., Aisner, J., Stein, M., Malhotra, J., Shih, W., Chan, N., Silk, A., Ganesan, S., Goodin, S., Gounder, M., Lin, H., Li, J., Cerchio, R., Marinar...> ;Oncotarget. 2023 Apr 10
• 6 citations
  A phase Ib dose-escalation study of troriluzole (BHV-4157), an oral glutamatergic signaling modulator, in combination with nivolumab in patients with advanced solid tu...
  Ann W Silk, Biren Saraiya, Roman Groisberg, Nancy Chan, Kristen Spencer, Eugenia Girda, Weichung Shih, Marisa Palmeri, Tracie Saunders, Robert M Berman, Vlad Coric, Su...> ;European Journal of Medical Research. 2022 Jul 2
• 3 citations
  Phase I trial of daily subcutaneous SPL-108 injections in combination with paclitaxel in patients with platinum resistant CD44+ advanced ovarian epithelial cancer.
  Eugenia Girda, June Hou, David Nelson, Malcolm Finlayson, Alexandre Buckley de Meritens, Marina Chekmareiva, Aliza Leiser, Mihae Song, Ruth Stephenson, Nancy Chan, Ana...> ;International Journal of Gynecological Cancer. 2022 Jun 24
• 6 citations
  Clinical outcomes and immune phenotypes associated withco-occurring mutations in non-small cell lung cancer.
  Jyoti Malhotra, Brid Ryan, Malini Patel, Nancy Chan, Yanxiang Guo, Joseph Aisner, Salma K Jabbour, Sharon Pine> ;Journal of Thoracic Disease. 2022 Jun 1
• 7 citations
  A phase I study of talazoparib (BMN 673) combined with carboplatin and paclitaxel in patients with advanced solid tumors (NCI9782).
  Ticiana A Leal, Marina N Sharifi, Nancy Chan, Robert Wesolowski, Anita A Turk, Justine Y Bruce, Ruth M O'Regan, Jens Eickhoff, Lisa M Barroilhet, Jyoti Malhotra, Janic...> ;Cancer Medicine. 2022 Nov 1
• 84 citations
  Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers.
  M Palmeri, J Mehnert, A W Silk, S K Jabbour, S Ganesan, P Popli, G Riedlinger, R Stephenson, A B de Meritens, A Leiser, T Mayer, N Chan, K Spencer, E Girda, J Malhotra...> ;ESMO Open. 2022 Feb 1
• 1 citations
  Toxicities and Locoregional Control After External Beam Chest Wall and/or Regional Lymph Node Re-irradiation for Recurrent Breast Cancer.
  Mutlay Sayan, Irina Vergalasova, Imraan Jan, Shicha Kumar, Nancy Chan, Bruce G Haffty, Nisha Ohri> ;Anticancer Research. 2022 Jan 1
• 10 citations
  Immune Checkpoint Inhibitors in Triple Negative Breast Cancer: The Search for the Optimal Biomarker.
  Sadaf Qureshi, Nancy Chan, Mridula George, Shridar Ganesan, Deborah Toppmeyer, Coral Omene> ;Biomarker Insights. 2022 Jan 1
• 1 citations
  A phase I study of veliparib with cyclophosphamide and veliparib combined with doxorubicin and cyclophosphamide in advanced malignancies
  Antoinette R. Tan, Nancy Chan, Brian F. Kiesel, Mark N. Stein, Rebecca A. Moss, Jyoti Malhotra, Joseph Aisner, Mansi Shah, Murugesan Gounder, Hongxia Lin, Michael P. K...> ;Cancer Chemotherapy and Pharmacology. 2021 Oct 20
• 8 citations
  Durable Response to PD1 Inhibitor Pembrolizumab in a Metastatic, Metaplastic Breast Cancer.
  Elan Gorshein, Kant Matsuda, Gregory Riedlinger, Levi Sokol, Lorna Rodriguez-Rodriguez, Firas Eladoumikdachi, Miral S. Grandhi, Shridar Ganesan, Deborah Toppmeyer, Lin...> ;Case Reports in Oncology. 2021 Jun 18
• 2 citations
  Neratinib + capecitabine sustains health-related quality of life in patients with HER2-positive metastatic breast cancer and ≥ 2 prior HER2-directed regimens
  Beverly Moy, Mafalda Oliveira, Cristina Saura, William J. Gradishar, Sung Bae Kim, Adam Brufsky, Sara A. Hurvitz, Larisa Ryvo, Daniele Fagnani, Sujith Kalmadi, Paula S...> ;Breast Cancer Research and Treatment. 2021 Apr 28
• 5 citations
  Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy
  Firas Al-Zubaydi, Dayuan Gao, Dipti Kakkar, Shike Li, Jennifer Holloway, Zoltan Szekely, Nancy Chan, Shicha Kumar, Hatem E. Sabaawy, Susan Love, Patrick J. Sinko> ;Drug Delivery and Translational Research. 2021 Feb 15
• 4 citations
  Correction: Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recur...
  Nancy Chan, Amy Willis, Naomi Kornhauser, Maureen M Ward, Sharrell B Lee, Eleni Nackos, Bo Ri Seo, Ellen Chuang, Tessa Cigler, Anne Moore, Diana Donovan, Marta Vallee ...> ;Clinical Cancer Research. 2020 Sep 15
• 58 citations
  Improved tolerability of neratinib in patients with HER2-positive early-stage breast cancer: the CONTROL trial.
  Carlos H. Barcenas, Sara A. Hurvitz, J. A. Di Palma, Ron Bose, A.J. Chien, N. Iannotti, G. Marx, Adam Brufsky, A. Litvak, E. Ibrahim, R.H. Alvarez, Manuel Ruiz-Borrego...> ;Annals of Oncology. 2020 Sep 1
• 11 citations
  Breast intraductal nanoformulations for treating ductal carcinoma in situ I: Exploring metal-ion complexation to slow ciclopirox release, enhance mammary persistence a...
  Firas Al-Zubaydi, Dayuan Gao, Dipti Kakkar, Shike Li, Derek Adler, Jennifer Holloway, Zoltan Szekely, Zichao Gu, Nancy Chan, Shicha Kumar, Susan Love, Patrick J. Sinko> ;Journal of Controlled Release. 2020 Jul 10
• 11 citations
  A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors.
  Charlotte Lemech, Natasha Woodward, Nancy Chan, Joanne E. Mortimer, Louie Naumovski, Silpa Nuthalapati, Bo Tong, Fang Jiang, Peter Ansell, Christine K. Ratajczak, Jasg...> ;Investigational New Drugs. 2020 Jun 10
• 153 citations
  Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors
  Rastilav Bahleda, Antoine Italiano, Cinta Hierro, Alain C. Mita, Andrés Cervantes, Nancy Chan, Mark M. Awad, Emiliano Calvo, Victor Moreno, Ramaswamy Govindan, Alexand...> ;Clinical Cancer Research. 2019 Aug 15
• 42 citations
  Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.
  Mark N. Stein, Jyoti Malhotra, Rohinton Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert Aiken, Tina M. Mayer, Bruce G. Haffty,...> ;Journal for Immunotherapy of Cancer. 2019 May 22
• 140 citations
  Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer.
  Anshuman Panda, Janice M. Mehnert, Kim M. Hirshfield, Greg Riedlinger, Sherri Damare, Tracie Saunders, Michael P. Kane, Levi Sokol, Mark N. Stein, Elizabeth Poplin, Lo...> ;Journal of the National Cancer Institute. 2018 Mar 1
• The Final Verdict: Chemotherapy Benefits Estrogen Receptor-Negative Isolated Local Recurrence.
  Nancy Chan, Deborah Toppmeyer> ;Journal of Clinical Oncology. 2018 Feb 27
• 13 citations
  Inference of Germline Mutational Status and Evaluation of Loss of Heterozygosity in High-Depth, Tumor-Only Sequencing Data.
  Hossein Khiabanian, Kim M. Hirshfield, Mendel Goldfinger, Simon Bird, Mark N. Stein, Joseph Aisner, Deborah Toppmeyer, Serena Wong, Nancy Chan, Kalyani Dhar, Jinesh S....> ;JCO Precision Oncology. 2018 Jan 19
• 100 citations
  First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors
  Mark N. Stein, Joseph R. Bertino, Howard L. Kaufman, Tina M. Mayer, Rebecca A. Moss, Ann W. Silk, Nancy Chan, Jyoti Malhotra, Loma Rodriguez, Joseph Aisner, Robert Aik...> ;Clinical Cancer Research. 2017 Aug 1
• 49 citations
  Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in...
  Nancy Chan, Amy Willis, Naomi Kornhauser, Maureen M Ward, Sharrell B Lee, Eleni Nackos, Bo Ri Seo, Ellen Chuang, Tessa Cigler, Anne Moore, Diana Donovan, Marta Vallee ...> ;Clinical Cancer Research. 2017 Feb 1
• 6 citations
  Then and Now: Comparison of Baseline Breast Cancer Screening Rates at 2 Time Intervals
  Georgia Robins Sadler, Jenny Hung, Paula R. Beerman, Mary Chen, Janice Chow, Nancy Chan> ;Journal of Cancer Education. 2009 Mar 6
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Lectures

• A phase I study of pazopanib with weekly paclitaxel and carboplatin in advanced solid tumors. 
  ASCO Annual Meeting 2019 - Chicago, IL - 6/1/2019