Nancy Uan-Tsin Lin MD

Breast Cancer

Associate Professor of Medicine, Harvard Medical School; Associate Chief, Division of Breast Oncology Center, Dana-Farber Cancer Institute

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44 Binney St# Dana-FarBoston, MA 02115
Phone+1 617-632-3800
Fax+1 617-632-1930

Education & Training

Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2002 - 2005
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 1999 - 2002
Harvard Medical SchoolClass of 1999

Certifications & Licensure

FL State Medical License 2022 - Present
MA State Medical License 2002 - 2027
VT State Medical License 2023 - 2026
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Lapatinib in Combination With Trastuzumab in Patients With HER2-Positive, Metastatic Breast Cancer Start of enrollment: 2007 May 14
COMPLETED
PHASE2
Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer Start of enrollment: 2007 Apr 01
Completed
Phase 1
ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases Start of enrollment: 2007 Jul 01
Terminated
Phase 2
Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU
TERMINATED
PHASE3
Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases Start of enrollment: 2009 Nov 01
Completed
Phase 2
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
ACTIVE_NOT_RECRUITING
PHASE3
Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer Start of enrollment: 2011 Aug 01
Completed
Phase 1, Phase 2
GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases Start of enrollment: 2011 Oct 01
Completed
Phase 2
Fulvestrant With or Without Ganetespib in HR+ Breast Cancer
ACTIVE_NOT_RECRUITING
PHASE2
A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer Start of enrollment: 2012 Jun 01
Completed
Phase 2
BKM120 For Triple Negative Breast Cancer Start of enrollment: 2012 Jun 01
Completed
Phase 2
ARRY-380 + Trastuzuamab for Breast w/ Brain Mets
COMPLETED
PHASE1
Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer Start of enrollment: 2014 May 01
Terminated
Phase 1, Phase 2
Avoiding Growth Factor During Paclitaxel Treatment in Breast Cancer Start of enrollment: 2016 Apr 07
Completed
Phase 2
Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC Start of enrollment: 2018 May 21
ACTIVE_NOT_RECRUITING
PHASE2
Clinical Information and Biospecimen Collection from Patients with Recurrent or Stage IV Breast Cancer Start of enrollment: 2019 Sep 16
SUSPENDED
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Clinicogenomic characterization of inflammatory breast cancer.
Nolan Priedigkeit, Beth Harrison, Robert Shue, Melissa E Hughes, Yvonne Li
Clinical Cancer Research. 2025-05-16
Nivolumab plus low-dose ipilimumab in hypermutated HER2-negative metastatic breast cancer: a phase II trial (NIMBUS).
Romualdo Barroso-Sousa, Jorge Gomez Tejeda Zanudo, Tianyu Li, Sangeetha M Reddy, Leisha A Emens
Nature Communications. 2025-05-13
1 citations
RANO criteria for response assessment of brain metastases based on amino acid PET imaging.
Nathalie L Albert, Norbert Galldiks, Benjamin M Ellingson, Martin J van den Bent, Susan M Chang
Nature Medicine. 2025-05-08

Journal Articles

Attitudes of Patients with Metastatic Cancer Towards Research Biopsies
Nancy Lin, MD, Asia‐Pacific Journal of Clinical Oncology

Press Mentions

CBD Trial Shows Promise for Cancer Anxiety ReliefDecember 17th, 2024
Managing Central Nervous System Metastasis in Patients with HER2-Positive Breast CancerOctober 22nd, 2024
T-dXd Demonstrated Intracranial Activity in HER2+ Breast CancerOctober 5th, 2024
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