NanetteSantoroMD

Obstetrics & Gynecology • Denver, CO

Reproductive Endocrinology & Infertility

Professor, Obstetrics & Gynecology, University of Colorado School of Medicine

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Office
Cherry Creek Medical Center
100 Cook Street
Denver, CO 80206
Phone+1 720-674-7157

Fax+1 720-516-9438
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Education & Training

Massachusetts General HospitalResidency, Internal Medicine, 1985 - 1989
Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1983 - 1985
Icahn School of Medicine at Mount Sinai (Beth Israel)Residency, Obstetrics and Gynecology, 1979 - 1983
Albany Medical CollegeClass of 1979

Certifications & Licensure

CO State Medical License 2010 - 2025
NY State Medical License 1980 - 2010
NJ State Medical License 1988 - 2009
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Reproductive Endocrinology/Infertility

Awards, Honors, & Recognition

Outstanding Mentor Award Endocrine Society, 2016
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Top Doctors: New York Metro Area Castle Connolly, 2003-2009
Westchester Magazine: Top Doctors Castle Connolly, 2004-2008
New York Magazine: Top Doctors Castle Connolly, 2004-2005
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
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Clinical Trials

KEEPS Cognitive and Affective Study Start of enrollment: 2007 May 01
Pregnancy in Polycystic Ovary Syndrome II Start of enrollment: 2009 Feb 01
Completed
Phase 3
Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis Start of enrollment: 2010 May 01
Terminated
Phase 3
Registry of Pregnancies Conceived Following Exposure to Ovulation Stimulation Medications Start of enrollment: 2009 May 01
Completed
The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes Start of enrollment: 2010 Mar 01
Completed
Phase 3
Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation Start of enrollment: 2010 Jun 01
Completed
Phase 3
Reproductive Medicine Network Biologic Specimen Repository Start of enrollment: 2010 Sep 01
Completed
Reproductive Hormonal Alterations in Obesity Start of enrollment: 2010 Jun 01
Completed
Not Applicable
Mirena and Estrogen for Control of Perimenopause Symptoms and Ovulation Suppression Start of enrollment: 2012 Apr 01
Completed
Not Applicable
Mediators of Abnormal Reproductive Function in Obesity (MARO) Start of enrollment: 2013 Mar 01
Completed
Early Phase 1
Reprometabolic Syndrome Mediates Subfertility in Obesity Start of enrollment: 2016 Jun 01
Completed
Not Applicable
The PrISICE Clinical Trial (Pre-Implantation Screening and Investigation on the Cryopreservation of Embryos) Start of enrollment: 2018 Aug 21
Terminated
Not Applicable
Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis Start of enrollment: 2022 Mar 15
Recruiting
Phase 3
Roles: Principal Investigator
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Publications & Presentations

PubMed

Acceptability and Feasibility of Initiating a Low Fat Eating Plan in Reproductive Aged Women with Obesity.
Nicola Hendricks, Lauren Gibbs, Katherine Kuhn, Andrew P Bradford, Nanette Santoro, Dorothy Mitchell-Leef> ;Reproductive Sciences. 2024 Apr 15
1 citations
Fezolinetant treatment of moderate-to-severe vasomotor symptoms due to menopause: effect of intrinsic and extrinsic factors in two phase 3 studies (SKYLIGHT 1 and 2).
Rossella E Nappi, Marci English, Deanna D King, Yusuke Yamaguchi, Faith D Ottery, Nanette Santoro, Genevieve Neal-Perry> ;Menopause. 2024 Apr 1
Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife.
Susanna D Mitro, Lauren A Wise, L Elaine Waetjen, Catherine Lee, Siobán D Harlow, Daniel H Solomon, Rebecca C Thurston, Samar R El Khoudary, Monique M Hedderson, Eve Z...> ;JAMA Network Open. 2024 Apr 1
Cost-effectiveness analysis of expectant versus active management for treatment of persistent pregnancies of unknown location.
Nathanael C Koelper, Heping Zhang, Tracey R Thomas, Hao Huang, , Jessica R Walter, Kurt T Barnhart, Nanette F Santoro, Heidi S Harvie> ;American Journal of Obstetrics and Gynecology. 2024 Mar 27
An egg is not a chicken and an embryo is not a child.
Eve C Feinberg, Nanette Santoro, Marcelle I Cedars, Paula Amato> ;Fertility and Sterility. 2024 Mar 18
Effectiveness of preconception weight loss interventions on fertility in women: a systematic review and meta-analysis.
Ann E Caldwell, Anna M Gorczyca, Andrew P Bradford, Jacinda M Nicklas, Robert N Montgomery, Heather Smyth, Shannon Pretzel, Thy Nguyen, Kristen DeSanto, Celia Ernstrom...> ;Fertility and Sterility. 2024 Feb 24
How Sex Hormones Affect Migraine: An Interdisciplinary Preclinical Research Panel Review.
Godley, F. A., John Meitzen, Hadas Nahman-Averbuch, Mary Angela O'Neal, David Yeomans, Nanette Santoro, Nina Riggins, Lars Edvinsson, Frederick Godley 3rd> ;Journal of Personalized Medicine. 2024 Feb 7
Fezolinetant impact on health-related quality of life for vasomotor symptoms due to the menopause: Pooled data from SKYLIGHT 1 and SKYLIGHT 2 randomised controlled tri...
Cano, A., Nappi, R., Stute, P., Blogg, M., English, M., Morga, A., Scrine, L., Siddiqui, E., Ottery, F., Santoro, N.> ;BJOG. 2024 Feb 6
Mathematical recapitulation of the end stages of human ovarian aging.
Lawley, S., Sammel, M., Johnson, J., Santoro, N.> ;Science Advances. 2024 Jan 12
Association of duration of embryo culture with risk of large for gestational age delivery in cryopreserved embryo transfer cycles.
Roshong, A., Santoro, N., Pier, B., Sammel, M.> ;Fertility and Sterility. 2024 Jan 5
The Fit After Baby randomized controlled trial: An mHealth postpartum lifestyle intervention for women with elevated cardiometabolic risk.
Pyle, L., Soares, A., Leiferman, J., Bull, S., Tong, S., Caldwell, A., Nicklas, J., Santoro, N., Barbour, L.> ;Plos One. 2024 Jan 1
A high-fat eucaloric diet induces reprometabolic syndrome of obesity in normal weight women.
Kuhn, K., Pretzel, S., Schauer, I., Fought, A., D'Alessandro, A., Stephenson, D., Bradford, A., Santoro, N.> ;PNAS Nexus. 2024 Jan 1
Masters of the menstrual cycle or masters of the life cycle?
Santoro, N.> ;Fertility and Sterility. 2024 Feb 1
Should menopause care be part of the skill set of a reproductive endocrinology and infertility specialist?
Schirmer, D., Berga, S., Merkison, J., Kawwass, J., Santoro, N.> ;Fertility and Sterility. 2024 Feb 1
Cardiometabolic outcomes in Kronos Early Estrogen Prevention Study continuation: 14-year follow-up of a hormone therapy trial.
Kejal Kantarci, Nirubol Tosakulwong, Timothy G Lesnick, Firat Kara, June Kendall-Thomas, Ekta Kapoor, Julie A Fields, Taryn T James, Rogerio A Lobo, JoAnn E Manson, Lu...> ;Menopause. 2024 Jan 1
"Weight loss is my goal and being healthy is my goal… I can get over the hot flashes": a qualitative exploration of menopausal transition experiences and preferences f...
Chelsea L Kracht, Jessica St Romain, Julie C Hardee, Nanette Santoro, Leanne M Redman, Kara L Marlatt> ;Menopause. 2023 Oct 1
Moderate and increased physical activity is not detrimental to live birth rates among women with unexplained infertility and obesity.
Wendy S Vitek, Fangbai Sun, Eden Cardozo, Kathleen M Hoeger, Karl R Hansen, Nanette Santoro, Heping Zhang, Richard S Legro> ;F&S Reports. 2023 Sep 1
1 citations
NK3R antagonists: a novel approach for menopause symptoms.
Simone Elder, Nanette Santoro> ;Nature Reviews. Endocrinology. 2023 Nov 1
1 citations
Sex Hormones, the Stool Microbiome, and Subclinical Atherosclerosis in Women With and Without HIV.
Brandilyn A Peters, David B Hanna, Yi Wang, Kathleen M Weber, Elizabeth Topper, Allison A Appleton, Anjali Sharma, Howard N Hodis, Nanette Santoro, Chantal Guillemette...> ;The Journal of Clinical Endocrinology and Metabolism. 2024 Jan 18
Reply of the author: "A day in the life of a reproductive endocrinologist and infertility subspecialist-integration or dissolution?"
Nanette Santoro> ;Fertility and Sterility. 2023 Oct 1
Do Your Ovaries Keep You Slim? WHAM Says No.
Nanette Santoro> ;The Journal of Clinical Endocrinology and Metabolism. 2024 Jan 18
Scholarly activity following National Institutes of Health Women's Reproductive Health Research K12 training-a cohort study.
Erin E McCoy, Ronit Katz, Diana K N Louden, Emiko Oshima, Amy Murtha, Nanette Santoro, Elizabeth A Howell, Lisa Halvorson, Susan D Reed, Barbara A Goff, Gyamfi-Bannerm...> ;American Journal of Obstetrics and Gynecology. 2023 Oct 1
1 citations
Type and age of menopause: potential implications for female sexual health.
Jill Liss, Jessica Pettigrew, Nanette Santoro> ;The Journal of Sexual Medicine. 2023 Jun 28
2 citations
Neurokinin receptor antagonists as potential non-hormonal treatments for vasomotor symptoms of menopause.
Melissa Conklin, Nanette Santoro> ;Therapeutic Advances in Reproductive Health. 2023 Jun 22
A day in the life of a reproductive endocrinologist and infertilty subspecialist-integration or dissolution?
Nanette Santoro> ;Fertility and Sterility. 2023 Jul 1
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Journal Articles

Vitamin D Deficiency Is Associated with Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility
Suneeta Senapati, Nanette Santoro, Richard S Legro, Samantha F Butts, Andrew N Hoofnagle, The Journal of Clinical Endocrinology and Metabolism
Allostatic Load, a Measure of Chronic Physiological Stress, Is Associated with Pregnancy Outcomes, but Not Fertility, Among Women with Unexplained Infertility
Valerie Baker, Peter Casson, Nanette Santoro, Wendy Vitek, Richard S Legro, Randal Robinson, G Wright Bates, Christos Coutifaris, Karl Hansen, Ruben Alvero, Esther Eis..., Human Reproduction
Gestational Weight Gain in Women with Polycystic Ovary Syndrome: A Controlled Study
Ruben Alvero, Peter Casson, Gregory M Christman, Karl R Hansen, William D Schlaff, Nanette Santoro, Christos Coutifaris, The Journal of Clinical Endocrinology and Metabolism
Letter to the Editor: Higher TSH Levels Within the Normal Range Are Associated with Unexplained Infertility
Clarisa Gracia, Nanette Santoro, The Journal of Clinical Endocrinology and Metabolism
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Lectures

Colorado Integrative Medicine Conference (cIMc 2013): Focus on Mind-Body Medicine & Lifestyle Management
Altermed Research Foundation, Estes Park, Colorado - 7/12/2013

Authored Content

Fertility-Related Quality of Life, Gonadal Function, and Erectile Dysfunction in Male Partners of Couples with Unexplained InfertilityMarch 2019
Religiosity and Faith in Relation to Time to Metabolic Syndrome for Hispanic Women in a Multiethnic Cohort of Women—Findings from the Study of Women’s Health Across the Nation (SWAN)March 2018
Religiosity and Faith in Relation to Time to Metabolic Syndrome for Hispanic Women in a Multiethnic Cohort of Women—Findings from the Study of Women’s Health Across the Nation (SWAN)March 2018

Press Mentions

What to Know About the New Treatment for Hot FlashesMay 12th, 2023
Perimenopause: Tackling the Dearth of Treatments for Anxiety and DepressionMarch 8th, 2023
Women Have Been Misled About MenopauseFebruary 1st, 2023
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Grant Support

Colorado Womens Reproductive Health Research Career Development CenterNICHD2015–2019
Reprometabolic Syndrome Mediates Subfertilty in ObesityNICHD2015–2019
The Clinical Research/Reproductive Scientist Training ProgramNICHD2013–2018
The Colorado Building Interdisciplinary Research Careers in Womens HealthNICHD2011–2016