
Nathan Benj Fountain MD
Epilepsy, Neurophysiology
Professor of Neurology
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1221 Hospital DrCharlottesville, VA 22908
Phone+1 434-924-2706
Fax+1 434-924-9068
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Summary
- Nathan B. Fountain, M.D. is the Thomas E. Worrell, Jr Professor of Neurology and Epileptology, Director of the F.E. Dreifuss Comprehensive Epilepsy Program, and Director of EEG and Epilepsy Fellowships at the University of Virginia School of Medicine where he completed neurology residency as well as clinical neurophysiology and clinical and research epilepsy fellowships.
Dr. Fountain's clinical interests include drug, device, and surgical treatment of epilepsy. His research focuses on clinical trials of new drugs and devices for epilepsy and other clinical research. He was formerly chair of the FDA Advisory Committee for Peripheral and Central Nervous System Drugs and president of the National Association of Epilepsy Centers and the Epilepsy Foundation Professional Advisory Board and is founding co-chair of the Epilepsy Foundation's Research Roundtable for Epilepsy. He sits on the board of directors for Acumen Pharmaceuticals, is co-founder of Hexokine Therapeutics, and is chair of the scientific advisory board for Shackleford Pharma.
Education & Training
University of Virginia Medical CenterFellowship, Clinical and Experimental Epilepsy, 1994 - 1996
University of Virginia Medical CenterFellowship, Clinical Neurophysiology, 1993 - 1994
University of Virginia Medical CenterResidency, Neurology, 1990 - 1993
University of Virginia Medical CenterInternship, Internal Medicine, 1989 - 1990
University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1989
Certifications & Licensure
VA State Medical License 1992 - 2028
TN State Medical License 1997 - 2005
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Epilepsy
Awards, Honors, & Recognition
- Top Doctors Castle Connolly, 2011-2022
- CMS Meaningful Use Stage 1 Certification EpicCare Inpatient - Core EMR, Epic Systems Corporation, 2013-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2013-2017
Clinical Trials
- RNS® System Pivotal Study Start of enrollment: 2005 Dec 01
- Radiosurgery or Open Surgery for Epilepsy Trial Start of enrollment: 2009 Sep 01
- MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001) Start of enrollment: 2016 Jun 07
Publications & Presentations
PubMed
- A randomized feasibility pilot trial of a remotely delivered physical activity intervention for adults with epilepsy.Halley B Alexander, Nathaniel O'Connell, Heidi M Munger Clary, Carolina Burgos-Aguilar, Case Peters
Epilepsy & Behavior. 2026-07-01 - Associations Between Testing and Treatment Pathways in a Case of Pediatric Nonlesional Epilepsy: A Census Survey of NAEC Center Directors.Christopher W Beatty, Stephanie M Ahrens, Kristen H Arredondo, Anto I Bagic, Shasha Bai
Journal of Child Neurology. 2025-03-01 - Preclinical toxicity studies supporting 2DG for treatment of status epilepticus.Thomas P Sutula, Nathan B Fountain
Epilepsy & Behavior. 2024-11-01
Press Mentions
- U.S. FDA Panel Votes Cannot Ignore Unsuccessful Trial Data on Biogen Alzheimer's DrugNovember 6th, 2020
Epilepsy Foundation and Its Partners Announce Epilepsy Learning Healthcare SystemJune 17th, 2019
Can Focused Sound Waves Fix Rare ‘Giggling’ Form of Epilepsy?June 2nd, 2018
Grant Support
- 2-deoxy-glucose oral pharmacokinetic and tolerability study in patients with epilepsyEpilepsy Foundation2019–2023
- Trial Of Harkoseride For Partial SeizuresNational Center For Research Resources2000–2002
- New Anticonvulsant (Ucb L059) In ChildrenNational Center For Research Resources1999–2000
- Inhibition In Enthorhinal Cortex In Chronic EpilepsyNational Institute Of Neurological Disorders And Stroke1998–2000
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