NeelroopNarendraParikshakMDPhD(He/Him)

PubMed

• A large meta-analysis identifies genes associated with anterior uveitis.
  Sahar Gelfman, Arden Moscati, Santiago Mendez Huergo, Rujin Wang, Veera Rajagopal, Neelroop Parikshak, Vijay Kumar Pounraja, Esteban Chen, Michelle Leblanc, Ralph Hazl...> ;Nature Communications. 2023 Nov 11
• 4 citations
  LIF signaling regulates outer radial glial to interneuron fate during human cortical development.
  Madeline G Andrews, Clara Siebert, Li Wang, Matthew L White, Jayden Ross, Raul Morales, Megan Donnay, Gradi Bamfonga, Tanzila Mukhtar, Arpana Arjun McKinney, Kaila Gem...> ;Cell Stem Cell. 2023 Oct 5
• 7 citations
  Rare coding variants in CHRNB2 reduce the likelihood of smoking.
  Veera M Rajagopal, Kyoko Watanabe, Joelle Mbatchou, Ariane Ayer, Peter Quon, Deepika Sharma, Michael D Kessler, Kavita Praveen, Sahar Gelfman, Neelroop Parikshak, Jacq...> ;Nature Genetics. 2023 Jul 1
• Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes.
  Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li, Kyoko Watanabe, Anthony Marketta, Michael Van Meter, Stefan Semrau, Julie Horowitz, Jing T...> ;Nature. 2023 Mar 1
• 56 citations
  Common and rare variant associations with clonal haematopoiesis phenotypes.
  Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li, Kyoko Watanabe, Anthony Marketta, Michael Van Meter, Stefan Semrau, Julie Horowitz, Jing T...> ;Nature. 2022 Dec 1
• 47 citations
  Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
  Michael J Gandal, Jillian R Haney, Brie Wamsley, Chloe X Yap, Sepideh Parhami, Prashant S Emani, Nathan Chang, George T Chen, Gil D Hoftman, Diego de Alba, Gokul Ramas...> ;Nature. 2022 Nov 1
• 61 citations
  Tropism of SARS-CoV-2 for human cortical astrocytes.
  Madeline G Andrews, Tanzila Mukhtar, Ugomma C Eze, Camille R Simoneau, Jayden Ross, Neelroop Parikshak, Shaohui Wang, Li Zhou, Mark Koontz, Dmitry Velmeshev, Clara-Vit...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jul 26
• Integrative functional genomic analysis of human brain development and neuropsychiatric risks.
  Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Cho...> ;Science (New York, N.Y.).
• 170 citations
  Histone Acetylome-wide Association Study of Autism Spectrum Disorder
  Wenjie Sun, Jeremie Poschmann, Ricardo C.H. del Rosario, Neelroop N. Parikshak, Hajira Shreen Hajan, Vibhor Kumar, Ramalakshmi Ramasamy, T. Grant Belgard, Bavani Elang...> ;Cell. 2016 Nov 17
• 140 citations
  The road to precision psychiatry: translating genetics into disease mechanisms.
  Michael J. Gandal, Virpi Leppa, Hyejung Won, Neelroop N. Parikshak, Daniel H. Geschwind> ;Nature Neuroscience. 2016 Nov 1
• The PsychENCODE project.
  PsychENCODE Consortium, Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, ...> ;Nature neuroscience.
• A quantitative framework to evaluate modeling of cortical development by neural stem cells.
  Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwin...> ;Neuron.
• Corrigendum: Case Report: A False Negative Case of Anti-Yo Paraneoplastic Myelopathy.
  Christopher M Bartley, Neelroop N Parikshak, Thomas T Ngo, Jessa A Alexander, Kelsey C Zorn, Bonny D Alvarenga, Min K Kang, Massimo Pedriali, Samuel J Pleasure, Michae...> ;Frontiers in Neurology. 2022 Jan 1
• 2 citations
  Case Report: A False Negative Case of Anti-Yo Paraneoplastic Myelopathy.
  Christopher M. Bartley, Neelroop N. Parikshak, Thomas T. Ngo, Jessa A. Alexander, Kelsey C. Zorn, Bonny A. Alvarenga, Min K. Kang, Massimo Pedriali, Samuel J. Pleasure...> ;Frontiers in Neurology. 2021 Oct 22
• 53 citations
  Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue.
  Chloe C. Y. Wong, Rebecca G. Smith, Eilis Hannon, Gokul Ramaswami, Neelroop N. Parikshak, Elham Assary, Claire Troakes, Jeremie Poschmann, Leonard C. Schalkwyk, Wenjie...> ;Human Molecular Genetics. 2019 Jul 1
• 8 citations
  Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap.
  Michael J. Gandal, Jillian R. Haney, Neelroop N. Parikshak, Virpi Leppa, Gokul Ramaswami, Christopher Hartl, Andrew J. Schork, Vivek Appadurai, Alfonso Buil, Thomas We...> ;Focus. 2019 Jan 10
• 18 citations
  Integrative network analysis reveals biological pathways associated with Williams syndrome.
  Ryo Kimura, Vivek Swarup, Kiyotaka Tomiwa, Michael J. Gandal, Neelroop N. Parikshak, Yasuko Funabiki, Masatoshi Nakata, Tomonari Awaya, Takeo Kato, Kei Iida, Shin Okaz...> ;Journal of Child Psychology and Psychiatry, and Allied Disciplines. 2019 May 1
• 85 citations
  Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing
  Alberto Parras, Héctor Anta, María Santos-Galindo, Vivek Swarup, Ainara Elorza, Jose Luis Nieto-Gonzalez, Sara Picó, Ivó H. Hernández, Juan Ignacio Díaz-Hernández, Eul...> ;Nature. 2018 Aug 15
• 4 citations
  Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.
  Neelroop N. Parikshak, Vivek Swarup, T. Grant Belgard, Manuel Irimia, Gokul Ramaswami, Michael J. Gandal, Christopher Hartl, Virpi Leppa, Luis de la Torre Ubieta, Jerr...> ;Nature. 2018 Aug 1
• 103 citations
  Sex-chromosome dosage effects on gene expression in humans.
  Armin Raznahan, Neelroop N. Parikshak, Vijayendran Chandran, Jonathan D. Blumenthal, Liv S. Clasen, Aaron Alexander-Bloch, Andrew R. Zinn, Danny Wangsa, Jasen Wise, De...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 10
• 40 citations
  Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex
  Matthew Schwede, Shailender Nagpal, Michael J. Gandal, Neelroop N. Parikshak, Karoly Mirnics, Daniel H. Geschwind, Eric M. Morrow> ;Journal of Neurodevelopmental Disorders. 2018 Jun 1
• 618 citations
  Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
  Michael J. Gandal, Jillian R. Haney, Neelroop N. Parikshak, Virpi Leppa, Gokul Ramaswami, Christopher Hartl, Andrew J. Schork, Vivek Appadurai, Alfonso Buil, Thomas We...> ;Science. 2018 Feb 9
• 418 citations
  Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism
  Neelroop N. Parikshak, Vivek Swarup, T. Grant Belgard, Manuel Irimia, Gokul Ramaswami, Michael J. Gandal, Christopher Hartl, Virpi Leppa, Luis de la Torre Ubieta, Jerr...> ;Nature. 2016 Dec 15
• 345 citations
  Chromosome conformation elucidates regulatory relationships in developing human brain
  Hyejung Won, Luis de la Torre-Ubieta, Jason L. Stein, Neelroop N. Parikshak, Jerry Huang, Carli K. Opland, Michael J. Gandal, Gavin J. Sutton, Farhad Hormozdiari, Dani...> ;Nature. 2016 Oct 27
• 132 citations
  Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder
  Ye E Wu, Neelroop N. Parikshak, T. Grant Belgard, Daniel H. Geschwind> ;Nature Neuroscience. 2016 Nov 1
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Journal Articles

• Autism-like Phenotype and Risk Gene mRNA Deadenylation by CPEB4 Mis-Splicing  
  Daniel H Geschwind, Neelroop N Parikshak, Nature
• Sex-Chromosome Dosage Effects on Gene Expression in Humans  
  Daniel H Geschwind, Neelroop N Parikshak, Andrew R Zinn, Judith Ross, Proceedings of the National Academy of Sciences