NeilKumarSinglaMD

Anesthesiology • Pasadena, CA

Chief Scientific Officer at Lotus Clinical Research

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Office
100 W. California Blvd, Unit 25
Pasadena, CA 91105
Phone+1 626-397-2390

Fax+1 626-628-0384
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Summary

Dr. Neil Singla, MD is an anesthesiologist in Pasadena, California. He is currently licensed to practice medicine in California. He is affiliated with Huntington Health.

Education & Training

Loma Linda University Health Education ConsortiumResidency, Anesthesiology, 1998 - 2001
Hamot Medical CenterInternship, Transitional Year, 1996 - 1997
Northeast Ohio Medical UniversityClass of 1996

Certifications & Licensure

CA State Medical License 1997 - 2023

Clinical Trials

Single Ascending Dose Safety, Tolerability and Pharmacokinetics Study of GLYX-13 in Normal Volunteers Start of enrollment: 2009 Nov 01
Completed
Phase 1
An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS Start of enrollment: 2014 Mar 01
Completed
Phase 4
An Open Label, Prospective Study of the Analgesic Efficacy of Oral Xartemis Compared to Generic Oxycodone/APAP( Acetaminophen) in the Treatment of Moderate to Severe Post Operative Pain. Start of enrollment: 2014 May 01
Completed
Phase 4
Study Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal Women Start of enrollment: 2016 Oct 07
Terminated
Phase 3
Phase 2 Herniorrhaphy Study for Opioid Elimination Start of enrollment: 2018 Oct 01
Completed
Phase 2
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Publications & Presentations

PubMed

A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty.
Alina C Beaton, Daneshvari Solanki, Hernan Salazar, Steve Folkerth, Neil Singla, Harold S Minkowitz, David Leiman, Ben Vaughn, Nina Skuban, Gwendolyn Niebler> ;Regional Anesthesia and Pain Medicine. 2023 Dec 1
10 citations
Intravenous Tramadol is Effective in the Management of Postoperative Pain Following Abdominoplasty: A Three-Arm Randomized Placebo- and Active-Controlled Trial
Harold S. Minkowitz, Hernan Salazar, David A. Leiman, Daneshvari Solanki, Lucy Lu, Scott A Reines, Michael Ryan, Mark Harnett, Neil Singla> ;Drugs in R&D. 2020 Sep 1
32 citations
Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations
Jennifer S. Gewandter, Robert H. Dworkin, Dennis C. Turk, Eric Devine, David J. Hewitt, Mark P. Jensen, Nathaniel P. Katz, Amy A. Kirkwood, Richard Malamut, John D. Ma...> ;The Journal of Pain. 2020 Sep 1
5 citations
IV Tramadol - A New Treatment Option for Management of Post-Operative Pain in the US: An Open-Label, Single-Arm, Safety Trial Including Various Types of Surgery.
Harold S. Minkowitz, David A. Leiman, Lucy Lu, Scott A Reines, Michael Ryan, Mark Harnett, Neil Singla> ;Journal of Pain Research. 2020 May 22
34 citations
Characterisation and monitoring of postoperative respiratory depression: current approaches and future considerations
Sabry Ayad, Ashish Khanna, Sheikh Usman Iqbal, Neil Singla> ;British Journal of Anaesthesia. 2019 Sep 1
96 citations
APOLLO-2: A Randomized, Placebo and Active-Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein–Biased Ligand at the μ-Opioid Receptor, for Manag...
Neil Singla, Franck Skobieranda, David G. Soergel, Monica Y Salamea, David A. Burt, Mark A. Demitrack, Eugene R. Viscusi> ;Pain Practice. 2019 Jun 24
89 citations
APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for manage...
Eugene R. Viscusi, Franck Skobieranda, David G. Soergel, Emily Cook, David A. Burt, Neil Singla> ;Journal of Pain Research. 2019 Mar 11
5 citations
Intravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects.
Eugene R. Viscusi, Tong J. Gan, Sergio D. Bergese, Neil Singla, Randall J Mack, Stewart W. McCallum, Wei Du, Sue Hobson> ;Regional Anesthesia and Pain Medicine. 2019 Feb 7
7 citations
Safety and efficacy of an intravenous nanocrystal formulation of meloxicam in the management of moderate to severe pain following laparoscopic abdominal surgery.
Neil Singla, Stewart W. McCallum, Randall J Mack, Alex Freyer, Sue Hobson, Wei Du> ;Journal of Pain Research. 2018 Sep 18
3 citations
Pharmacokinetics of Fentanyl Sublingual Spray in Opioid-Naïve Participants: Results of a Phase 1, Multiple Ascending Dose Study.
Richard Rauck, D. Alexander Oh, Neil Singla, Christian Koch, Neha Parikh, Srinivas Nalamachu, Jin Yu, Steven James> ;Clinical Drug Investigation. 2018 Aug 1
19 citations
Efficacy and Safety of Intravenous Meloxicam in Subjects with Moderate-to-severe Pain Following Abdominoplasty.
Neil Singla, Matthew Bindewald, Sonia Singla, David A. Leiman, Harold S. Minkowitz, Mccallum Stewart, Randall J Mack, Rosemary Keller, Alex Freyer, Wei Du> ;Plastic and Reconstructive Surgery. Global Open. 2018 Jun 19
3 citations
Exploring the Interplay between Rescue Drugs, Data Imputation, and Study Outcomes: Conceptual Review and Qualitative Analysis of an Acute Pain Data Set.
Neil K Singla, Diana S Meske, Paul J Desjardins> ;Pain and Therapy. 2017 Dec 1
Erratum to: Exploring the Interplay between Rescue Drugs, Data Imputation, and Study Outcomes: Conceptual Review and Qualitative Analysis of an Acute Pain Data Set.
Neil K Singla, Diana S Meske, Paul J Desjardins> ;Pain and Therapy. 2017 Dec 1
2 citations
Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a multiple ascending dose study in opioid-naïve healthy volunteers.
Richard L Rauck, D Alexander Oh, Neil Singla, Christian Koch, Neha Parikh, Srinivas Nalamachu, Daniel Wilson, Jin Yu, Santosh Vetticaden> ;Current Medical Research and Opinion. 2017 Nov 1
1 citations
Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a single ascending dose study in opioid-naïve healthy volunteers.
Richard Rauck, D Alexander Oh, Neha Parikh, Christian Koch, Neil Singla, Jin Yu, Srinivas Nalamachu, Santosh Vetticaden> ;Current Medical Research and Opinion. 2017 Nov 1
111 citations
A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (μ-GPS) modulator, for the management of moderate to s...
Neil Singla, Harold S. Minkowitz, David G. Soergel, David A. Burt, Ruth Ann Subach, Monica Y Salamea, Michael J. Fossler, Franck Skobieranda> ;Journal of Pain Research. 2017 Oct 6
24 citations
Sufentanil Sublingual Tablet 30 mcg for the Management of Pain Following Abdominal Surgery: A Randomized, Placebo-Controlled, Phase-3 Study
Harold S. Minkowitz, David A. Leiman, Timothy I. Melson, Neil Singla, Karen P. DiDonato, Pamela Pierce Palmer> ;Pain Practice. 2017 Sep 1
8 citations
Postoperative opioid sparing with injectable hydroxypropyl-β-cyclodextrin-diclofenac: pooled analysis of data from two Phase III clinical trials.
Tong J. Gan, Neil Singla, Stephen E. Daniels, Douglas A. Hamilton, Peter G. Lacouture, Christian Russel D. Reyes, Daniel B. Carr> ;Journal of Pain Research. 2016 Dec 20
Reply.
Singla N, Desjardins PJ> ;Pain. 2016-10-01
A Pooled Analysis Evaluating Renal Safety in Placebo- and Active Comparator-Controlled Phase III Trials of Multiple-Dose Injectable HPβCD-Diclofenac in Subjects with A...
Daniels SE, Gan TJT, Hamilton DA, Singla N, Lacouture PG, Johnson O, Min LH, Reyes CRD, Carr DB> ;Pain Med. 2016-07-17
A Pooled Analysis Evaluating Renal Safety in Placebo- and Active Comparator-Controlled Phase III Trials of Multiple-Dose Injectable HPβCD-Diclofenac in Subjects with A...
Neil Singla, Douglas A Hamilton, Daniel B Carr> ;British Journal of Anaesthesia. 2016 Dec 28
14 citations
Cardiovascular safety of hydroxypropyl-β-cyclodextrin-diclofenac in the management of acute postsurgical pain: a pooled analysis of 2 randomized, double-blind, placebo...
Tong J. Gan, Neil Singla, Stephen E. Daniels, Peter G. Lacouture, Lauren H. Min, Christian Russel D. Reyes, Daniel B. Carr> ;Journal of Clinical Anesthesia. 2016 Jun 1
22 citations
Assay Sensitivity of Pain Intensity Versus Pain Relief in Acute Pain Clinical Trials: ACTTION Systematic Review and Meta-Analysis
Neil Singla, Matthew Hunsinger, Phoebe D. Chang, Michael P. McDermott, Amit K. Chowdhry, Paul J. Desjardins, Dennis C. Turk, Robert H. Dworkin> ;The Journal of Pain. 2015 Aug 1
10 citations
Delayed-onset muscle soreness: a pilot study to assess analgesic study design features
Neil Singla, Paul J. Desjardins, Evelyn B. Cosca, Cherri Parulan, Anne Arriaga, Kelly C. Poole, Dan M. Batz, Phoebe D. Chang> ;Pain. 2015 Jun 1
5 citations
Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen table...
Neil Singla, Rachel Margulis, Kenneth Kostenbader, Yanping Zheng, Thomas Barrett, Michael J. Giuliani, Yin Chen, Jim L Young> ;The Physician and Sportsmedicine. 2015 Apr 26
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Press Mentions

Unintended Consequences of COVID-19 Safety Measures on Patients with Chronic Knee Pain Forced to Defer Joint Replacement SurgeryOctober 12th, 2020
Trevena Announces Publication of APOLLO-2 Results in Pain PracticeJune 24th, 2019
Accelerating Development of Non-Opioid Pain MedicinesMay 22nd, 2019
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Hospital Affiliations

Huntington HealthPasadena, California