
Nestoras Nicolas Mathioudakis MD MHS (He/him)
Diabetes, Lipid Metabolism
Associate Professor, Endocrinology, Diabetes, & Metabolism; Co-Medical Director, Baltimore Metropolitan Diabetes Regional Partnership
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601 North Caroline StreetFloor 2Baltimore, MD 21287
Phone+1 410-955-9270
Fax+1 410-367-2042
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Summary
- Dr. Nestoras Mathioudakis is an endocrinologist in Lutherville, MD and is affiliated with multiple hospitals in the area, including Johns Hopkins Hospital, Johns Hopkins Bayview Medical Center, and Johns Hopkins Hospital. He received his medical degree from Johns Hopkins University School of Medicine and has been in practice 10 years. He also speaks multiple languages, including Greek and French. He specializes in diabetes and lipid metabolism.
Education & Training
Johns Hopkins UniversityFellowship, Endocrinology, Diabetes, and Metabolism, 2009 - 2012
Johns Hopkins UniversityResidency, Internal Medicine, 2006 - 2009
Johns Hopkins University School of MedicineClass of 2006
Johns Hopkins UniversityBA, French, 1997 - 2001
Certifications & Licensure
FL State Medical License 2021 - Present
MD State Medical License 2012 - 2027
VA State Medical License 2021 - 2026
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Baltimore Top Doc - Diabetes Care Baltimore Magazine, 2020-2021
- Baltimore Top Doc - Endocrinology Baltimore Magazine, 2018
- Phi Beta Kappa Johns Hopkins University, 1999
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Clinical Trials
- Diabetes Prevention Program Outcomes Study Start of enrollment: 2002 Sep 01
- Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs Start of enrollment: 2021 Oct 01
Roles: Contact, Principal Investigator
- Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes Start of enrollment: 2016 Oct 10
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Publications & Presentations
PubMed
- Semaglutide and diabetic retinopathy: an OHDSI network study.Cindy Xinji Cai, Akihiko Nishimura, Sally Baxter, Kerry Goetz, Michelle Hribar
BMJ Open Diabetes Research & Care. 2025-11-04 - Machine Learning to Diagnose Complications of Diabetes.Agatha F Scheideman, Mandy M Shao, Henry Zelada, Jorge Cuadros, Joshua Foreman
Journal of Diabetes Science and Technology. 2025-11-01 - Continuous Glucose Monitoring Data Analysis 2.0: Functional Data Pattern Recognition and Artificial Intelligence Applications.David C Klonoff, Richard M Bergenstal, Eda Cengiz, Mark A Clements, Daniel Espes
Journal of Diabetes Science and Technology. 2025-11-01
Journal Articles
- Development and Validation of a Machine Learning Model to Predict near-Term Risk of Iatrogenic Hypoglycemia in Hospitalized PatientsNestoras N Mathioudakis, Mihail Zilbermint, JAMA Network Open
- ACTH-secreting pituitary microadenomas are associated with a higher prevalence of central hypothyroidism compared to other microadenoma typesMathioudakis N, Thapa S, Wand GS, Salvatori R, Clin Endocrinol (Oxf.), 5/15/2012
- A lifelong smoker with hypopituitarism: rethinking the hypothesis of a tumore in the hypophysisMathioudakis N, Quinones-Hinojosa A, Salvatori R, Basaria S, Case Report Med, 1/1/2012
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Books/Book Chapters
Lectures
- "Thyroid Nodules and Thyroid Cancer"Johns Hopkins School of Medicine - 12/1/2013
- "Thyroid Disorders"Johns Hopkins School of Nursing - 11/1/2013
- "Diabetes: A Cardiovascular Disease"Trinidad and Tobago - 10/1/2013
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Other
- U-500 insulin.Mathioudakis N, The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Technology Center)
Baltimore, MD - 8/1/2013 - Insulin Pumps.Mathioudakis N, The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Technology Center)
Baltimore, MD - 8/1/2013 - Global Health and Diabetes.Mathioudakis N, The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Technology Center)
Baltimore, MD - 8/1/2013 - Join now to see all
Authored Content
- The Society for Vascular Surgery Wound, Ischemia, and Foot Infection (WIfI) Classification System Predicts Wound Healing Better Than Direct Angiosome Perfusion in Diabetic Foot WoundsJanuary 2018
Press Mentions
AI Diabetes Prevention Program Yields Similar Results as Human-Led ProgramNovember 13th, 2025
AI-Powered Coach Effective as a Human in Preventing DiabetesNovember 6th, 2025
A New Kind of Coach: How Artificial Intelligence Is Helping People Prevent DiabetesOctober 31st, 2025- Join now to see all
Grant Support
- Implementation of a diabetes navIgator to Mitigate disPArities and improve CGM upTake and sustained use across the lifespan of T1D (IMPACT T1D)JOHNS HOPKINS UNIVERSITY2022–2026
- Effectiveness of Digital Versus In-Person Diabetes Prevention ProgramsJOHNS HOPKINS UNIVERSITY2020–2025
- Supplement to Effectiveness of Digital Versus In-Person Diabetes Prevention ProgramsJOHNS HOPKINS UNIVERSITY2020–2025
- Effectiveness of Digital Versus In-Person Diabetes Prevention ProgramsNIDDK2020–2025
- Implementation and Evaluation of a Real-Time Informatics Alert to Prevent Insulin-Associated Hypoglycemia in the Hospital.NIH- NIDDK2016–2020
Committees
- Clinical Director, Division of Endocrinology, Diabetes, & Metabolism 2016 - Present
- Chair, Glucose Steering Committee 2015 - Present
- Associate Director, Inpatient Diabetes Management Service, Johns Hopkins Hospital 2012 - 2016
Research History
- Co-principal investigatorDiabetes Prevention Program Outcomes Study (Johns Hopkins site)2012 - Present
- Postdoctoral FellowStudied the role of pituitary stem cells in pituitary tumorigenesis (Lab of Dr. Alfredo Quinones-HInojosa)2009 - 2012
Professional Memberships
- Member
- Member
- Member
Other Languages
- Greek, French
Industry Relationships
- Principle investigator, Sweetch Health LTDPersonalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With PrediabetesDisclosure: None2015 - Present
External Links
- Hopkins Profilehttp://www.hopkinsmedicine.org/profiles/results/search/
- Hopkins Endocrinologyhttp://www.hopkinsmedicine.org/endocrinology_diabetes_metabolism/our_team/
- Lab Websitehttps://www.nestorasmathioudakislab.com/
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