NicholasJospeMD

PubMed

• 6 citations
  Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Rece...
  Yury Kryvalap, Chi-Wen Lo, Ekaterina Manuylova, Raman Baldzizhar, Nicholas Jospe, Jan Czyzyk> ;The Journal of Biological Chemistry. 2016 Jan 1
• 5 citations
  Avidity-dependent programming of autoreactive T cells in T1D.
  Ivana Durinovic-Belló, Vivian H. Gersuk, Chester Ni, Rebecca P. Wu, Jerill Thorpe, Nicholas Jospe, Srinath Sanda, Carla J. Greenbaum, Gerald T. Nepom> ;Plos One. 2014 May 20
• 19 citations
  Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report—HLA Class I Tetramer Validation Init...
  Roberto Mallone, Matthieu Scotto, Claire Nicola Janicki, Eddie A. James, Lisa Fitzgerald-Miller, Rebecca Wagner, Peter A. Gottlieb, Jerill Thorpe, Nicholas Jospe, Ivan...> ;Diabetes/metabolism Research and Reviews. 2011 Nov 1
• 20 citations
  Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.
  Eddie A. James, Roberto Mallone, Nanette C. Schloot, Marie-Claude Gagnerault, Jerill Thorpe, Lisa Fitzgerald-Miller, Jessica Reichow, Rebecca Wagner, M. N. Pham, Nicho...> ;Diabetes/metabolism Research and Reviews. 2011 Nov 1
• 19 citations
  Uncoupling of Proliferation and Cytokines From Suppression Within the CD4+CD25+Foxp3+ T–Cell Compartment in the 1st Year of Human Type 1 Diabetes
  Angela Hughson, Irina Bromberg, Barbara Johnson, Sally A. Quataert, Nicholas Jospe, Deborah J. Fowell> ;Diabetes. 2011 Aug 1
• 2 citations
  Growth hormone deficiency and HIV infection.
  Geoffrey A. Weinberg, Nicholas Jospe> ;The Journal of Pediatrics. 2005 Oct 1
• 37 citations
  Continuous subcutaneous insulin infusion in toddlers and children with type 1 diabetes mellitus is safe and effective.
  Jean E. Mack-Fogg, Craig C. Orlowski, Nicholas Jospe> ;Pediatric Diabetes. 2005 Mar 1
• Hermaphroditus in Greco-Roman myth: lessons and hypotheses for intersex today.
  Nicholas Jospe, Monica Florence> ;Journal of Pediatric Endocrinology & Metabolism. 2004 Nov 1
• 41 citations
  Comprehensive Assessment of Professional Competence: The Rochester Experiment
  Ronald M. Epstein, Elaine F. Dannefer, Anne C. Nofziger, John T. Hansen, Stephen Schultz, Nicholas Jospe, Laura W. Connard, Sean Meldrum, Lindsey C. Henson> ;Teaching and Learning in Medicine. 2004 Jan 1
• 11 citations
  Third-year medical student survey of office preceptorships during the pediatric clerkship
  Nicholas Jospe, Paul B. Kaplowitz, Fred A. McCurdy, Ruth P. Gottlieb, Mitch A. Harris, Russell Boyle> ;Archives of Pediatrics & Adolescent Medicine. 2001 May 1
• 5 citations
  Hyponatremia secondary to reset osmostat in a child with a central nervous system midline defect and a chromosomal abnormality.
  P Gupta, G Mick, Chin-To Fong, Nicholas Jospe, K McCormick> ;Journal of Pediatric Endocrinology & Metabolism. 2000 Jan 1
• 1 citations
  Ambiguity of the external genitalia in an infant with Down syndrome: gender assignment and ethical implications.
  Nicholas Jospe, Andrew Lane, Jane Greenlaw, Stephen B. Sulkes> ;Mental Retardation. 1999 Jun 1
• 9 citations
  BACK TO BASICS: Fluids and Electrolytes—Clinical Aspects
  Nicholas Jospe, Gilbert B. Forbes> ;Pediatrics in Review. 1996 Nov 1
• 7 citations
  Deletion of Lysine 121 Creates a Temperature-sensitive Alteration in Insulin Binding by the Insulin Receptor
  Ruichun Liu, Jian Zhu, Nicholas Jospe, Richard W. Furlanetto, William Bastian, James N. Livingston> ;The Journal of Biological Chemistry. 1995 Jan 6
• 36 citations
  Comparison of transdermal and oral estrogen therapy in girls with Turner's syndrome.
  Nicholas Jospe, Craig C. Orlowski, Richard W. Furlanetto> ;Journal of Pediatric Endocrinology & Metabolism. 1995 Jan 1
• 17 citations
  Deletion of 3 basepairs resulting in the loss of lysine-121 in the insulin receptor alpha-subunit in a patient with leprechaunism: binding, phosphorylation, and biolog...
  Nicholas Jospe, Jin Zhu, Ruichun Liu, James N. Livingston, Richard W. Furlanetto> ;The Journal of Clinical Endocrinology and Metabolism. 1994 Nov 1
• 16 citations
  Melanocytic Nevi in Turner Syndrome
  Brad Becker, Nicholas Jospe, Lowell A. Goldsmith> ;Pediatric Dermatology. 1994 Jun 1
• 7 citations
  Temporal and individual variations in the dose of glucocorticoid used for the treatment of salt-losing congenital virilizing adrenal hyperplasia due to 21-hydroxylase ...
  R Sandrini, Nicholas Jospe, Claude J. Migeon> ;Acta Paediatrica . Supplement. 2008 Jan 21
• 27 citations
  Growth hormone deficiency in an 8-year-old girl with human immunodeficiency virus infection.
  Nicholas Jospe, Keith R. Powell> ;Pediatrics. 1990 Aug 1
• 43 citations
  Two distinct areas of unequal crossingover within the steroid 21-hydroxylase genes produce absence of CYP21B.
  Patricia A. Donohoue, Nicholas Jospe, Claude J. Migeon, Cornelis Van Dop> ;Genomics. 1989 Oct 1
• 5 citations
  Factitious transient neonatal hyperthyrotropinemia
  Nicholas Jospe, G. D. Berkovitz, L. E. Corcoran, R. L. Humphrey> ;Journal of Endocrinological Investigation. 1988 Feb 1
• 12 citations
  Restriction fragment analysis of duplication of the fourth component of complement (C4A).
  Robert H. McLean, Patricia A. Donohoue, Nicholas Jospe, Wilma B. Bias, Cornelis Van Dop, Claude J. Migeon> ;Genomics. 1988 Jan 1
• 27 citations
  Prevalence of polymorphic 21-hydroxylase gene (Ca21HB) mutations in salt-losing congenital adrenal hyperplasia
  Nicholas Jospe, Patricia A. Donohoue, Cornelis Van Dop, Robert H. McLean, Wilma B. Bias, Claude J. Migeon> ;Biochemical and Biophysical Research Communications. 1987 Feb 13
• 6 citations
  Congenital adrenal hyperplasia: molecular mechanisms resulting in 21-hydroxylase deficiency.
  Patricia A. Donohoue, C Van Dop, Nicholas Jospe, Claude J. Migeon> ;Acta Endocrinologica. Supplementum. 1986 Dec 1
• 100 citations
  Gene conversion in salt-losing congenital adrenal hyperplasia with absent complement C4B protein.
  Patricia A. Donohoue, C Van Dop, Robert H. McLean, Perrin C. White, Nicholas Jospe, Claude J. Migeon> ;The Journal of Clinical Endocrinology and Metabolism. 1986 May 1
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Journal Articles

• A temperature sensitive mutant insulin receptor exhibiting negative cooperativity.  
  Liu, R., Zhu, J., Jospe, N., Furlanetto, RW., Livingston, JN, J. Biol. Chem
• Who has the power to stop the abuse of power?  
  O.J. Z. Sahler and Jospe, N, Annals of Behavioral Science and Medical Education

Books/Book Chapters

• Endocrine and Metabolic Disorders. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Berkow, R.Rahway, NJ. Edition 1,
• Endocrine Disorders. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Berkow, R.Rahway, NJEdition 17,
• Hyperthyroidism. 
  Chapter: Primary Pediatric Care 
  Page 1554 - 1557Jospe, NEditors: Hoekelman R, et al.Mosby Year Book Publishers, St. LouisEdition 4,
• Disorders of Puberty. 
  Chapter: Pediatrics 
  Jospe, NEditors: Osborn, Dewitt, First, and Zenel.
• Disorders of Sexual Differentiation. 
  Chapter: Pediatrics 
  Jospe, NEditors: Osborn, Dewitt, First, and Zenel.
• Disorders of the Adrenal Gland. 
  Chapter: Pediatrics 
  Page 1031 - 1039Jospe, NEditors: Osborn, Dewitt, First, and Zenel.Fall
• Ambiguous Genitalia. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Garfunkel, Christy and Kaczaroswski.Harcourt, Health Sciences, St Louis, MO
• Diabetes Mellitus type 1. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Garfunkel, Christy and Kaczaroswski.Harcourt, Health Sciences, St Louis, MO
• Diabetes Mellitus type 2. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Garfunkel, Christy and Kaczaroswski.Harcourt, Health Sciences, St Louis, MO
• Diabetic ketoacidosis. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Christy and Kaczaroswski.Harcourt, Health Sciences, St Louis, MO
• Endocrinology. 
  Chapter: Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship 
  Jospe, NEditors: Woodhead JC.Mosby, St Louis, MO
• Growth problems. 
  Chapter: Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship 
  Jospe, NEditors: Woodhead JC.Mosby, St Louis, MO
• Computer-assisted Learning. 
  Chapter: Pediatrics Project, CLIPP 
  Jospe NEditors: LH Fall, A Olson, NB Berman Dartmouth, NH.
• Section on Endocrinology. 
  Chapter: Nelson Essentials of Pediatrics 
  Page 771 - 824Jospe, NEditors: W.B. Saunders.Philadelphia, PAEdition 5,
• Ambiguous Genitalia. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Editors Garfunkel, Christy and KaczarowskiEditors Garfunkel, Christy and Kaczarowski.Harcourt, Health Sciences, St Louis, MOEdition 2,
• Diabetes Mellitus type 1. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Editors Garfunkel, Christy and Kaczarowski.Harcourt, Health Sciences, St Louis, MO
• Diabetes Mellitus type 2. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Jospe,NEditors: Garfunkel, Christy and Kaczarowski.Harcourt, Health Sciences, St Louis, MOEdition 2,
• Diabetic ketoacidosis. 
  Chapter: Mosby’s Pediatric Clinical Advisor 
  Page 167 - 168Jospe,NEditors: Garfunkel, Christy and Kaczarowski.Harcourt, Health Sciences, St Louis, MO
• Diabetes in Childhood and Adolescence. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Beers, MH.Rahway, NJ
• Endocrine and Metabolic Disorders. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Beers, MH.Rahway, NJ
• Hyperthyroidism. 
  Chapter: Textbook of Pediatric Care 
  Page 2154 - 2157Jospe, NEditors: McInerny, T, et al.Mosby Year Book Publishers, St. Louis
• Endocrinology. 
  Chapter: Pediatric Clerkship Guide: Essential Guide to the Pediatric Clerkship 
  Jospe, NEditors: Woodhead JC.St Louis, MO
• Endocrine and Metabolic Disorders: pediatric diabetes. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Rahway, NJ.
• Endocrine and Metabolic Disorders. 
  Chapter: The Merck Manual of Medical Information 
  Jospe, NEditors: Beers, MH.Rahway, NJEdition 19,
• Section on Endocrinology. 
  Chapter: Nelson Essentials of Pediatrics 
  Jospe, NEditors: W.B. Saunders.Philadelphia, PAEdition 6,
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Abstracts/Posters

• Gene deletions of the fourth component of complement (C4) and 21-hydroxylase (21-OH) genes in salt-losing congenital adrenal hyperplasia.
  Jospe, N., Donohoue, P.A., Van Dop, C., McLean, R.H., White, P.C., Migeon, C.J, The Endocrine Society, Baltimore, MD
• Restriction fragment length polymorphisms of the fourth component of complement on duplicated C4 haplotypes.
  McLean, R.H., Donohoue, P.A., Jospe, N., Bias, W.B., Van Dop, C., Migeon, C.J, XIIth International Complement Workshop, Grenoble, France
• 21-Hydroxylase gene recombinations in patients with salt-losing congenital adrenal hyperplasia.
  Jospe, N., Donohoue, P.A., Van Dop, C., Migeon, C.J, The Society for Pediatric Research, Washington, D.C
• Pubertal changes in gonadotropin secretion of subjects with partial androgen insensitivity syndrome.
  Jospe, N., Brown, T.R., and Berkovitz, G.D, The Endocrine Society, Los Angeles, CA
• Growth hormone (GH) deficiency due to neurosecretory dysfunction in an eight year old girl with human immunodeficiency virus (HIV) infection.
  Jospe, N., Powell, K.R, Meeting of the Eastern Great Lakes Endocrine Society, Ithaca, NY
• Mutations of the insulin receptor gene in two patients with severe insulin resistance due to leprechaunism.
  Jospe, N., Livingston, J.N., Furlanetto, R.W, Meeting of the Eastern Great Lakes Endocrine Society, Rochester, NY
• Functional changes within the CD4+CD25+Foxp3 T cell compartment during remission Type 1 Diabetes Mellitus in children.
  Bromberg I, Hughson A, Johnson B, Quataert S, Jospe N. and Fowell D, 11th Annual Meeting of the Federation of Clinical Immunology Societies, Washington DC
• Heterozygous deletion of 3 base-pairs resulting in the deletion of lysine-121 in the insulin receptor -subunit from a patient with leprechaunism.
  Jospe, N., Zhu, J., Livingston, J.N., Furlanetto, R.W, The American Diabetes Association, Las Vegas, NE
• Homozygous mutation in the insulin receptor $-subunit of a patient with leprechaunism altering arginine 786 to a stop codon.
  Jospe, N., Kaplowitz, P.B., Furlanetto, R.W, The Endocrine Society, Las Vegas, NE
• Abnormal temperature sensitivity and negative cooperativity in an insulin receptor (IR) with deletion of Lys-121.
  Liu, R., Zhu, J., Jospe, N., Furlanetto, RW., Livingston, JN, The American Diabetes Association, New Orleans, LA
• The Power of the written word: balancing objectivity and sensitivity in the evaluation narrative.
  Jospe, N., Sahler O.J, 2nd Annual Meeting of The Council on Medical Education in Pediatrics, San Antonio, TX
• A survey of the reasons parents give for non-participation in the Diabetes Prevention Trial-type 1 (DPT-1).
  Jospe, N. Edwards Daniel, Sixth Florida Conference on Child Health Psychology
• A pediatric Dentistry Curriculum for the third-year Pediatric Clerkship.
  Jospe, N. Berkowitz, R. Sahler, OJ, Annual Meeting of The Association of Medical School Pediatric Chairs and Council on Medical Educatio, Bal Harbor, FL
• Ultrasound study in Turner syndrome.
  Hoeger, K. Jospe, N. Jaffe, R, National Association of Pediatric and Adolescent Gynecology
• Expanding the Teaching sites for the third-year Pediatric Clerkship in a time of decreasing Inpatient Census: Barriers and Solutions.
  Jospe, N.Algranati, P, Chartrand S, Annual Meeting of the Pediatric Academic Societies, San Francisco, CA
• Third-year Medical Student Survey of Office Preceptorships during the Pediatric Clerkship.
  Jospe, N. Kaplowitz, P. McCurdy FA, Gottlieb RP, Harris MA, Annual Meeting of the Pediatric Academic Societies, San Francisco, CA
• Helping Students Optimize Their Use of the Internet in Clinical Medicine.
  Swantz, R, and Jospe N, Annual Meeting of The Association of Medical School Pediatric Chairs and Council on Medical Edu, Vancouver, B.C
• Safe and effective use of continuous subcutaneous insulin infusion in young children with type 1 diabetes mellitus.
  Mack-Fogg, J., Bates, S., Faro, B., Sciera, M., Ippolito, K., Orlowski, C., Jospe, N, Annual Meeting of the Pediatric Academic Societies, Baltimore, MD
• Adoption of the electronic medical record in pediatric endocrinology.
  Vignare, C., Jospe, N, Presentation at the 22nd Annual meeting of the TEPR conference and Exhibition, Baltimore, MD
• Content of Narrative Peer Feedback among Second Year Medical Students.
  Nofziger AC, Jospe, N. and Epstein, RM, Annual Meeting of the Association of American Colleges, Washington, DC
• Content of Narrative Peer Feedback among Second Year Medical Students.
  Nofziger AC, Jospe, N. and Epstein, RM, Annual Educational Retreat of the Northeast Group on Educational Affairs, Stony Brook, New York
• The honeymoon period in type 1 Diabetes Mellitus.
  Jospe, N. Nepom, JT, Bi-annual meeting of the Immunology of Diabetes Society, Miami, FL
• Progressive Loss of Regulatory T cell Function from Diagnosis in Children with Type 1 Diabetes.
  Fowell. D, Johnson B, Jospe N, 9th Annual Meeting of the Federation of Clinical Immunology Societies, San Francisco, CA
• Progressive Loss of Regulatory T cell Function in the first year from Diagnosis in Children with Type 1 Diabetes Mellitus.
  Hughson A, Bromberg I, Johnson B, Fowell D, and Jospe, N, LWPES/ESPE 8th Joint Meeting, New York, NY
• Case report of an 11 year old male with gigantism and acromegaly without demonstrable growth hormone hypersecretion or increase in the Insulin-like growth factor-1 axis.
  Jospe, N, Fang P, Hwa V, and Rosenfeld R., LWPES/ESPE 8th Joint Meeting, New York, NY
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Lectures

• Syndromes of congenital insulin resistance. 
  Brookdale Hospital Medical Center, Brooklyn, NY
• Mutations of the Insulin Receptor Gene in Severe Congenital Insulin Resistance: Identification and Functional Characterization. 
  The Children’s Hospital, Pittsburgh, PA
• Treatment of New-Onset Type1 Diabetes Mellitus with an Anti-CD20 Monoclonal Antibody (Rituximab). 
  Autoimmune Center of Excellence, University of Rochester, Rochester, NY
• The Fetal Programming of Adult Endocrine Disease. 
  Benaroya Research Institute, Seattle WA
• Type 1 Diabetes Mellitus: some updates from Immunology. 
  Strong Children’s Research Center
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