NicholasASmyrniosMD

PubMed

• A Controlled Study in CPR-Survival in Propensity Score Matched Full-Code and Do-Not-Resuscitate ICU Patients.
  Nicholas A Smyrnios, Khaldoun Faris, Yurima Guilarte-Walker, Ugur Celik, Ulises Torres, Baldor, D.> ;Journal of Intensive Care Medicine. 2022 Oct 1
• Early Mobility for Critically Ill Patients: Building Staff Commitment Through Appreciative Inquiry.
  Michelle M Fernald, Nicholas A. Smyrnios, Joan Vitello> ;Critical Care Nurse. 2020 Aug 1
• 5 citations
  A Comparison of Non-Invasive Blood Pressure Measurement Strategies with Intra-Arterial Measurement.
  M Cornelia Pinkston, Nicholas A. Smyrnios, Stacy N. Weisberg> ;Prehospital and Disaster Medicine. 2020 Jul 21
• 1 citations
  Comparison of a Self-Inflating Bulb Syringe and a Colorimetric CO2 Indicator With Capnography and Radiography to Detect the Misdirection of Naso/Orogastric Tubes Into ...
  Nicholas A. Smyrnios, Richard Lenard, Sunil Rajan, Michael S. Newman, Stephen P. Baker, Nehal Thakkar, Wahid Wassef, Niraj K. Ajmere, Richard S. Irwin> ;Chest. 2015 Jun 1
• 29 citations
  The Sequential Organ Failure Assessment score and copeptin for predicting survival in ventilator-associated pneumonia
  Lucas Boeck, Philippe Eggimann, Nicholas A. Smyrnios, Hans Pargger, Nehal Thakkar, Martin Siegemund, Nils G. Morgenthaler, Janko Rakic, Michael Tamm, Daiana Stolz> ;Journal of Critical Care. 2012 Oct 1
• 39 citations
  Pancreatic stone protein: a marker of organ failure and outcome in ventilator-associated pneumonia
  Lucas Boeck, Rolf Graf, Philippe Eggimann, Hans Pargger, Dimitri A. Raptis, Nicholas A. Smyrnios, Nehal Thakkar, Martin Siegemund, Janko Rakic, Michael Tamm, Daiana Stolz> ;Chest. 2011 Oct 1
• 24 citations
  Midregional pro-atrial natriuretic peptide and procalcitonin improve survival prediction in VAP
  Lucas Boeck, Philippe Eggimann, Nicholas A. Smyrnios, Hans Pargger, Nehal Thakkar, Martin Siegemund, Stephan Marsch, Janko Rakic, Michael Tamm, Daiana Stolz> ;The European Respiratory Journal. 2011 Mar 1
• 218 citations
  Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study
  Daiana Stolz, Nicholas A. Smyrnios, Philippe Eggimann, Hans Pargger, Nehal Thakkar, Martin Siegemund, Stephan Marsch, Andrea Azzola, Janko Rakic, Beat Mueller, Michael...> ;The European Respiratory Journal. 2009 Dec 1
• 7 citations
  Applicability of Prediction Rules in Patients With Community-Acquired Pneumonia Requiring Intensive Care: A Pilot Study:
  Nicholas A. Smyrnios, Oren P. Schaefer, Roslinde M. Collins, J. Mark Madison> ;Journal of Intensive Care Medicine. 2005 Jul 1
• 63 citations
  Effects of a multifaceted, multidisciplinary, hospital-wide quality improvement program on weaning from mechanical ventilation.
  Nicholas A. Smyrnios, Ann E. Connolly, Mark M. Wilson, Frederick J. Curley, Cynthia T. French, Stephen O. Heard, Richard S. Irwin> ;Critical Care Medicine. 2002 Jun 1
• 16 citations
  The influence of liposome-encapsulated prostaglandin E1 on hydrogen peroxide concentrations in the exhaled breath of patients with the acute respiratory distress syndr...
  Stephen O. Heard, Karen J. Longtine, Ildiko Toth, Juan Carlos Puyana, Bruce Potenza, Nicholas A. Smyrnios> ;Anesthesia and Analgesia. 1999 Aug 1
• 45 citations
  From a Prospective Study of Chronic Cough Diagnostic and Therapeutic Aspects in Older Adults
  Nicholas A. Smyrnios, Richard S. Irwin, Frederick J. Curley, Cynthia L. French> ;Archives of Internal Medicine. 1998 Jun 8
• 10 citations
  The jury on femoral vein catheterization is still out.
  Nicholas A. Smyrnios, Richard S. Irwin> ;Critical Care Medicine. 1997 Dec 1
• 93 citations
  Interpretation of positive results of a methacholine inhalation challenge and 1 week of inhaled bronchodilator use in diagnosing and treating cough-variant asthma.
  Richard S. Irwin, Cynthia T. French, Nicholas A. Smyrnios, Frederick J. Curley> ;Archives of Internal Medicine. 1997 Sep 22
• 54 citations
  Accuracy of 30-minute indirect calorimetry studies in predicting 24-hour energy expenditure in mechanically ventilated, critically ill patients
  Nicholas A. Smyrnios, Frederick J. Curley, K G Shaker> ;JPEN. Journal of Parenteral and Enteral Nutrition. 1997 May 1
• 2 citations
  Asthma: a six-part strategy for managing older patients.
  Nicholas A. Smyrnios> ;Geriatrics. 1997 Feb 1
• 33 citations
  Chronic cough with a history of excessive sputum production. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific...
  N A Smyrnios, R S Irwin, F J Curley> ;Chest. 1995 Oct 1
• 8 citations
  Pleural effusion in an asymptomatic patient: spectrum and frequency of causes and management considerations
  Nicholas A. Smyrnios, Peter J. Jederlinic, Richard S. Irwin> ;Chest. 1990 Jan 1
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Journal Articles

• The effect of encapsulated PGE1 on systemic oxygen delivery and consumption in patients with the acute respiratory distress syndrome (ARDS).  
  Heard SO, Longtine K, Smyrnios N, Puyana JC, J Intensive Care Med;17:127-131
• Routine monitoring of critically ill patients.  
  Curley FJ, Smyrnios NA, J Intensive Care Med; 5:153-174
• Current concepts in the pathophysiology and management of near-drowning.  
  Smyrnios NA, Irwin RS, J Intensive Care Med; 6:26-35
• Clinicopathologic Conference: A critically ill patient with cholestatic jaundice and altered mental status.  
  Labarre R, Smyrnios NA, J Intensive Care Med;6:143-149
• Clinicopathologic Conference: A 47 year old woman with hypotension and recurrent pulmonary infiltrates.  
  Smyrnios NA, Forster R, Hollingsworth HM, Jederlinic PJ, Gitlin D, Clive D, Linden C, J Intensive Care Med;7:261-273
• Clinicopathologic Conference: A 37 year old woman with altered mental status, fever, and renal failure.  
  Smyrnios NA, Nitzberg MC, Irwin RS, et al, J Intensive Care Med;8:298-309
• Accuracy of 30 minute indirect calorimetry (IC) studies in predicting 24 hour energy expenditure (EE) in mechanically ventilated, critically ill patients.  
  Smyrnios NA, Curley FJ, Shaker KG, JPEN; 21:168-174
• The effect of liposome encapsulated PGE1 on systemic oxygen delivery and consumption in patients with the acute respiratory distress syndrome (ARDS).  
  Heard SO, Longtine K, Smyrnios N, Puyana JC, J Intensive Care Med;17:127-131
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Books/Book Chapters

• Review of Intensive Care Medicine. 
  Nicholas A. SmyrniosEditors: Smyrnios NA, Irwin RS, Cerra F, Rippe JM.Lippincott, Williams, & Wilkins, New York
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Indirect Calorimetry 
  Smyrnios NA, Curley FJEditors: RS Irwin, JM Rippe, F Cerra.Lippincott Williams & WilkinsEdition 4,
• Internal Medicine Pearls. 
  Chapter: A 54 year old woman with a persistent cough 
  Smyrnios NA, Irwin RSEditors: JE Heffner, SA Sahn. Hanley and Belfus.PhiladelphiaEdition 2,
• Manual of Intensive Care Medicine. 
  Chapter: Smyrnios NA, Curley FJ, Irwin RS 
  Page 106 - 110Smyrnios NA, Curley FJ, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott Williams& Wilkins, Philadelphia
• Manual of Intensive Care Medicine. 
  Chapter: Aspiration and Near-Drowning 
  Page 293 - 297Smyrnios NA, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott Williams& Wilkins, Philadelphia
• Cardiovascular Medicine, Practice and Management. 
  Chapter: Management of pulmonary emergencies 
  Smyrnios NA, Murillo BARC Becker, JS Alpert. Arnold Publishers, London
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Near-drowning 
  Smyrnios NA, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 5,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Routine Monitoring of Critically Ill Patients 
  Curley FJ, Smyrnios NAEditors: RS Irwin and JM Rippe.Lippincott Williams & WilkinsEdition 5,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Indirect Calorimetry 
  Smyrnios NA, Curley FJEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 5,
• Manual of Intensive Care Medicine. 
  Chapter: Indirect Calorimetry 
  Page 115 - 118Smyrnios NA, Curley FJEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 4,
• Manual of Intensive Care Medicine. 
  Chapter: Aspiration and Near Drowning 
  Smyrnios NA, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott, Williams & Wilkins
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Routine monitoring of Critically Ill Patients 
  Howell MD, Curley FJ, Smyrnios NAEditors: RS Irwin and JM Rippe.Lippincott Williams & WilkinsEdition 6,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Indirect Calorimetry 
  Page 256 - 260Smyrnios NA, Curley FJEditors: RS Irwin and JM Rippe.Lippincott Williams & WilkinsEdition 6,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Drowning 
  Page 607 - 613Smyrnios NA, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 6,
• Manual of Intensive Care Medicine. 
  Chapter: Aspiration and Drowning 
  Smyrnios NA, Irwin RSEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 5,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Routine Monitoring of Critically Ill Patients 
  Page 227 - 245Troy P, Smyrnios NA, Howell MDEditors: RS Irwin and JM Rippe.Lippincott Williams & WilkinsEdition 7,
• Irwin and Rippe’s Intensive Care Medicine. 
  Chapter: Mechanical Ventilation Part III: Discontinuation 
  Page 658 - 669Irwin RS, Smyrnios NA, Hubmayr RDEditors: RS Irwin and JM Rippe.Lippincott, Williams & WilkinsEdition 7,
• Intensive Care Medicine. 
  Chapter: Near-drowning 
  Page 532 - 539Smyrnios NA, Irwin RSEditors: JM Rippe, RS Irwin, JS Alpert, MP Fink.Little, Brown and Company, BostonEdition 2,
• Intensive Care Medicine. 
  Chapter: Monitoring in the ICU 
  Curley FJ, Smyrnios NAEditors: JM Rippe, RS Irwin, JS Alpert, MP Fink.Little, Brown and Company, BostonEdition 2,
• Pulmonary Disease in the Elderly Patient. 
  Chapter: Wheeze and Cough in the Elderly 
  Page 113 - 157Smyrnios NA, Irwin RSEditors: DA Mahler.Marcel Dekker, New York, NY
• Current Pulmonology. 
  Chapter: Chronic cough 
  Page 73 - 93Smyrnios NA, Irwin RSEditors: DF Tierney.Mosby, St. Louis
• Intensive Care Medicine. 
  Chapter: Near-drowning 
  Page 702 - 708Smyrnios NA, Irwin RSEditors: JM Rippe, RS Irwin, MP Fink, F Cerra.Little Brown and Company, BostonEdition 3,
• Intensive Care Medicine. 
  Chapter: Monitoring in the ICU 
  Page 275 - 294Curley FJ, Smyrnios NAEditors: JM Rippe, RS Irwin, MP Fink, F Cerra.Little Brown and Company, BostonEdition 3,
• Intensive Care Medicine. 
  Chapter: Indirect Calorimetry 
  Smyrnios NA, Curley FJEditors: JM Rippe, RS Irwin, MP Fink, F Cerra.Little Brown and Company, BostonEdition 3,
• Textbook of Internal Medicine. 
  Chapter: Approach to the patient with cough 
  Page 1912 - 1917Smyrnios NA, Irwin RSEditors: WN Kelley. J.B.Lippincott Company, PhiladelphiaEdition 3,
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Abstracts/Posters

• Indirect calorimetry in the medical ICU: Comparison with traditional practice and effect on cost of care.
  Smyrnios NA, Curley FJ, Jederlinic PJ, Hoffman P, Phillpotts M, Egan P, Larrivee G, Irwin RS, Am Rev Respir Dis; 141:A581
• Acute effects of nutritional changes and role in weaning.
  Smyrnios NA, Curley FJ, Jederlinic PJ, Hoffman P, Larrivee G, Chest; 98:103S
• The effect of inhaled metaproterenol on cough-variant asthma.
  Irwin RS, French CL, Smyrnios NA, Curley FJ, LaJeunesse SM, Lenard RA, Bennett, FM, Am Rev Respir Dis;145:A12
• Chronic cough in the elderly: Causes and outcome of diagnostic evaluation and specific therapy.
  Smyrnios NA, Curley FJ, French CL, Irwin RS, Am Rev Respir Dis; 147: A381
• Causes, evaluation, and treatment of chronic bronchorrhea.
  Smyrnios NA, Irwin RS, Curley FJ, Am Rev Respir Dis;147:A871
• The role of bronchoscopy following negative sputum induction in the diagnosis of pneumocystis carinii pneumonia in the HIV and non-HIV immunocompromised individual.
  Osmanski JO, Schaefer OP, Smyrnios NA, Horan GF, Am J Respir Crit Care Med;153:A437
• Short term impact of a multidisciplinary ventilator management program on quality of care, ICU utilization, and economics.
  Smyrnios NA, Irwin RS, Curley FJ, French CL, Bergeron J, Gaw V, Krikorian C, Am J Respir Crit Care Med;153:A548
• A multidisciplinary ventilator management program: improvement in quality of care, ICU utilization, and economics at one year.
  Smyrnios NA, Irwin RS, Connolly A, Curley FJ, Krikorian C, and the UMMC Ventilator Management Team, Am J Respir Crit Care Med;155: A19
• The effect of liposome encapsulated PGE1 (C-53) on hydrogen peroxide concentrations in the expired breath of patients with the acute respiratory distress syndrome.
  Hughes F, Longtine K, Smyrnios N, Puyana JC, Potenza B, Frassica J, Toth I, Heard S, Anesth Analg
• The effect of liposome encapsulated PGE1 on systemic oxygen delivery and consumption in patients with the acute respiratory distress syndrome.
  Heard SO, Longtine K, Smyrnios NA, Puyana JC, Crit Care Med;27:A125 (suppl.)
• Applicability of prediction rules in patients with severe community acquired pneumonia.
  Collins RM, Smyrnios NA, Schaefer OP, Am J Respir Crit Care Med;163: A806
• Nasojejunal feeding in pancreatitis: a single center experience.
  Marshall C, Wassef W, Smyrnios N, Leblanc G, American J Gastroenterology;106:s74
• Acute physiologic changes during threshold inspiratory resistive loading.
  Curley FJ, Jederlinic PJ, Smyrnios NA, Hoffman P, Am Rev Respir Dis; 141:A721
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Lectures

• 24th Annual Frontiers in Critical Care Nursing 
  University of Massachusetts Medical Center, Marlborough, Massachusetts - 5/7/2013
• Management of Hiccup. 
  American College of Chest Physicians, San Francisco, CA
• Programs for Weaning from Mechanical Ventilation – What works and how? 
  American College of Chest Physicians, Philadelphia, PA
• Programs for Weaning from Mechanical Ventilation – What works and how? What doesn’t work and why? 
  Pulmonary Grand Rounds, St. Elizabeth’s Hospital, Brighton, MA
• Unsuspected Bacterial Suppurative Disease of the Airways Presenting as Chronic Cough. 
  Chest 2002, Annual Meeting of the American College of Chest Physicians, San Diego, CA
• Mechanical Ventilation in Status Asthmaticus. 
  Chest 2005, Annual Meeting of the American College of Chest Physicians, Montreal, QC, Canada
• Use of Physician Extenders in the Intensive Care Unit. 
  Chest 2006, Annual Meeting of the American College of Chest Physicians, Salt Lake City, Utah
• Mechanical Ventilation in Status Asthmaticus. 
  Chest 2006, Annual Meeting of the American College of Chest Physicians, Salt Lake City, Utah
• Management of Acute Respiratory Distress Syndrome. 
  Medical Grand Rounds, Berkshire Medical Center, Pittsfield, MA
• Management of Acute Exacerbations of Asthma. 
  Athol Memorial Hospital, Athol, MA
• Management of Acute Respiratory Distress Syndrome. 
  Medical Grand Rounds, Harrington Hospital, Southbridge, MA
• Moderator, Ethics and Treatment Issues Discussion. 
  Medical Grand Rounds, UMass Memorial Medical Center, Worcester, MA
• Severe Acute respiratory Failure: Organizing Pneumonia. 
  Medical Grand Rounds M+M, UMass Memorial Medical Center, Worcester, MA
• Wheeze. 
  Symposium on Respiratory Care, UMMC Multidisciplinary Support Services Department, Sturbridge, MA
• Outpatient Mgt.of Asthma. 
  HIV Provider Group, Div. Of Infectious Diseases and Immunology, University of Massachusetts Medical
• New Medications for Asthma. 
  Asthma Awareness Group, Shrewsbury Middle School, Shrewsbury, MA
• Computers in Critical Care: Windows to the Future. 
  University of Massachusetts Medical School, Worcester, MA
• Impact of a Multidisciplinary Ventilator Management Protocol. 
  University of Massachusetts Medical School, Worcester, MA
• Computers In Critical Care: Windows to the Future. 
  Frontiers in Critical Care Medicine - Worcester, MA
• Weaning From Mechanical Ventilation - The UMass Experience. 
  N.E. States Chapter Meeting, American College of Chest Physicians, Worcester, MA
• Thrombolysis in Pulmonary Embolism. 
  Pulmonary Interhospital Conference, University of Massachusetts Medical School, Worcester, MA
• Outpatient Management of Asthma. Primary Care Lecture Series. 
  University of Massachusetts Medical School, Worcester, MA
• How to Monitor Quality and Performance in the ICU. 
  UMass Memorial Medical Center, Worcester, MA
• Programs for Weaning from Mechanical Ventilation – What works and how? What doesn’t work and why? 
  UMass Memorial Medical Center, Worcester, MA
• Acute Respiratory Distress Syndrome. 
  Beechwood Hotel, Worcester, MA
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Other

• Sailing or sinking ship? The pulmonary artery catheter treads water. 
  Smyrnios NA, Irwin RS, J Intensive Care Med; 12:113-115
• The jury on femoral venous catheters is still out. 
  Smyrnios NA, Irwin RS, Critical Care Medicine;25:1943-1946
• Editorial Consultant. 
  Smyrnios NA, Lippincott’s Interactive Critical Care Library on CD-ROM
  New York