NicolaMSpirtosMD

Obstetrics & Gynecology • Las Vegas, NV

General Gynecology, Gynecologic Oncology

Professor of Obstetrics & Gynecology

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Office
3131 La Canada St
Suite Number 241
Las Vegas, NV 89169
Phone+1 702-693-6870

Fax+1 702-693-6899
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Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Gynecologic Oncology, 1985 - 1987
University of Southern California/LAC+USC Medical CenterResidency, Obstetrics and Gynecology, 1981 - 1984
Northwestern University The Feinberg School of MedicineClass of 1980

Certifications & Licensure

NV State Medical License 1997 - 2025
CA State Medical License 1981 - 2025
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Gynecologic Oncology

Awards, Honors, & Recognition

Vegas Seven Castle Connolly, 2014
America's Top Doctors Castle Connolly, 2006-2011, 2013-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Desert Companion Castle Connolly, 2011
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
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Clinical Trials

Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer Start of enrollment: 2008 Feb 25
Active, not recruiting
Phase 2
Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer Start of enrollment: 2007 Dec 06
Active, not recruiting
Phase 3
Laparoscopic Approach to Cervical Cancer Start of enrollment: 2008 Jan 01
Completed
Not Applicable
Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Start of enrollment: 2012 Jun 18
Recruiting
Phase 3
CA-IX, p16, Proliferative Markers, and HPV in Diagnosing Cervical Lesions in Patients With Abnormal Cervical Cells Start of enrollment: 2009 Feb 09
Active, not recruiting
Not Applicable
Collecting Tumor Samples From Patients With Gynecological Tumors Start of enrollment: 1992 Jun 01
Completed
Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer Start of enrollment: 2012 Jun 01
Unknown status
Not Applicable
Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors Start of enrollment: 2010 Feb 08
Active, not recruiting
Phase 2
Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery Start of enrollment: 2010 Apr 12
Active, not recruiting
Phase 3
Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer Start of enrollment: 2012 Jan 09
Completed
Phase 3
Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery Start of enrollment: 2012 Jun 04
Terminated
Phase 3
Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Start of enrollment: 2012 Jun 18
Completed
Phase 3
Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva Start of enrollment: 2012 Jul 02
Active, not recruiting
Phase 2
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer Start of enrollment: 2012 Oct 01
Active, not recruiting
Not Applicable
Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer Start of enrollment: 2014 Feb 14
Terminated
Phase 2
Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer Start of enrollment: 2014 Mar 17
Active, not recruiting
Phase 2, Phase 3
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer Start of enrollment: 2014 Feb 27
Active, not recruiting
Phase 2, Phase 3
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Publications & Presentations

PubMed

1 citations
Corrigendum to "Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis" [Gynecologic Oncology ...
Kimberly Levinson, Anna Beavis, Christopher Purdy, Anne F. Rositch, Akila N. Viswanathan, Aaron H. Wolfson, Michael G. Kelly, Krishnansu S. Tewari, Leah McNally, Saket...> ;Gynecologic Oncology. 2021 Oct 12
22 citations
Beyond Sedlis—A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis
Kimberly Levinson, Anna Beavis, Christopher Purdy, Anne F. Rositch, Akila N. Viswanathan, Aaron H. Wolfson, Michael Kelly, Krishnansu S. Tewari, Leah McNally, Saketh R...> ;Gynecologic Oncology. 2021 Sep 1
54 citations
Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II
Maaike H. M. Oonk, Brian Slomovitz, Peter Baldwin, Helena C. van Doorn, Jacobus van der Velden, Joanne A. de Hullu, Katja N. Gaarenstroom, Brigitte F. M. Slangen, Igna...> ;Journal of Clinical Oncology. 2021 Aug 25
16 citations
A phase II randomized, double-blind trial of a polyvalent Vaccine-KLH conjugate (NSC 748933 IND# 14384) + OPT-821 versus OPT-821 in patients with epithelial ovarian, f...
Roisin E. O'Cearbhaill, Wei Deng, Lee-may Chen, Joseph A. Lucci, Kian Behbakht, Nick M. Spirtos, Carolyn Y. Muller, Benedict B. Benigno, Matthew A. Powell, Emily Berry...> ;Gynecologic Oncology. 2019 Dec 1
8 citations
The addition of paclitaxel to doxorubicin and cisplatin and volume-directed radiation does not improve overall survival (OS) or long-term recurrence-free survival (RFS...
Nick M. Spirtos, Danielle Enserro, Howard D. Homesley, Susan K. Gibbons, David Cella, Robert T. Morris, Koen DeGeest, Roger B. Lee, David Miller> ;Gynecologic Oncology. 2019 Jul 1
48 citations
Surgical-pathological findings in type 1 and 2 endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study on GOG-210 protocol ☆
William T. Creasman, Shamshad Ali, David G. Mutch, Richard J. Zaino, Matthew A. Powell, Robert S. Mannel, Floor J. Backes, Paul DiSilvestro, Peter A. Argenta, Michael ...> ;Gynecologic Oncology. 2017 Jun 1
13 citations
A stratified randomized double-blind phase II trial of celecoxib for treating patients with cervical intraepithelial neoplasia: The potential predictive value of VEGF ...
Janet S. Rader, Michael W. Sill, Jan H. Beumer, Heather A. Lankes, Doris M. Benbrook, Francisco A.R. Garcia, Connie Trimble, J. Tate Thigpen, Richard W. Lieberman, Ros...> ;Gynecologic Oncology. 2017 May 1
The complexities of benchmarking surgical complications in gynaecological oncology.
Spirtos NM> ;BJOG. 2016-12-01
67 citations
Impact of histology and surgical approach on survival among women with early-stage, high-grade uterine cancer: An NRG Oncology/Gynecologic Oncology Group ancillary ana...
Amanda N. Fader, James J. Java, Meaghan Tenney, Stephanie Ricci, Camille C. Gunderson, Sarah M. Temkin, Nick M. Spirtos, Christina L. Kushnir, Michael L. Pearl, Oliver...> ;Gynecologic Oncology. 2016 Dec 1
Radiological predictors of cytoreductive outcomes in women with advanced ovarian cancer.
CL Kushnir, NM Spirtos> ;BJOG. 2015 May 1
77 citations
Phase III Randomized Trial of Weekly Cisplatin and Irradiation Versus Cisplatin and Tirapazamine and Irradiation in Stages IB2, IIA, IIB, IIIB, and IVA Cervical Carcin...
Paul DiSilvestro, Shamshad Ali, Peter S. Craighead, Joseph A. Lucci, Yi-Chun Lee, David E. Cohn, Nicola M. Spirtos, Krishnasu S. Tewari, Carolyn Y. Muller, Walter H. G...> ;Journal of Clinical Oncology. 2014 Feb 10
1 citations
Authors' response to: Lymphadenectomy in ovarian cancer--an overrated procedure?
NM Spirtos> ;BJOG. 2013 Sep 1
3 citations
Defining the role of lymphadenectomy in gynaecological oncology
NM Spirtos> ;BJOG. 2013 Mar 1
Upper abdominal cytoreduction and thoracoscopy for advanced epithelial ovarian cancer: unanswered questions and the impact on treatment.
Fleury AC, Kushnir CL, Giuntoli RL, Spirtos NM> ;BJOG. 2012-01-01
Tumor heterogeneity in ovarian cancer as demonstrated by in vitro chemoresistance assays.
McAlpine JN, Eisenkop SM, Spirtos NM> ;Gynecol. Oncol.. 2008-09-01
The relative importance of surgical training and laboratory research in a gynecologic oncology fellowship.
Eisenkop SM, Spirtos NM> ;Int. J. Gynecol. Cancer. 2004-01-01
Regional blood flow occlusion during extensive pelvic procedures for ovarian cancer: a randomized trial.
Eisenkop SM, Spirtos NM, Lin WM, Rafidi F, Gross GM> ;Int. J. Gynecol. Cancer. 2004-01-01
Radiation fields in gynecologic oncology: correlation of soft tissue (surgical) to radiologic landmarks.
McAlpine J, Schlaerth JB, Lim P, Chen D, Eisenkop SM, Spirtos NM> ;Gynecol. Oncol.. 2004-01-01
131 citations
Radical trachelectomy and pelvic lymphadenectomy with uterine preservation in the treatment of cervical cancer
John B. Schlaerth, Nicola M. Spirtos, Alan C. Schlaerth> ;American Journal of Obstetrics and Gynecology. 2003 Jan 1
Surgical chores and approach in the management of endometrial cancer.
McAlpine JN, Spirtos NM, Chen MD> ;Curr Opin Oncol. 2002-09-01
66 citations
Laparoscopic retroperitoneal lymphadenectomy followed by immediate laparotomy in women with cervical cancer: a gynecologic oncology group study.
John B. Schlaerth, Nicola M. Spirtos, Linda F. Carson, Guy M. Boike, Thomas A. Adamec, Bette Stonebraker> ;Gynecologic Oncology. 2002 Apr 1
Procedures required to accomplish complete cytoreduction of ovarian cancer: is there a correlation with "biological aggressiveness" and survival?
Eisenkop SM, Spirtos NM> ;Gynecol. Oncol.. 2001-09-01
What are the current surgical objectives, strategies, and technical capabilities of gynecologic oncologists treating advanced epithelial ovarian cancer?
Eisenkop SM, Spirtos NM> ;Gynecol. Oncol.. 2001-09-01
The clinical significance of occult macroscopically positive retroperitoneal nodes in patients with epithelial ovarian cancer.
Eisenkop SM, Spirtos NM> ;Gynecol. Oncol.. 2001-07-01
Second-look laparotomy after modified posterior exenteration: patterns of persistence and recurrence in patients with stage III and stage IV ovarian cancer.
Spirtos NM, Eisenkop SM, Schlaerth JB, Ballon SC> ;Am. J. Obstet. Gynecol.. 2000-06-01
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Lectures

Through the Cloud: Demystifying Medical Marijuana
2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018

Professional Memberships

American College of Obstetricians and Gynecologists
Fellow

Hospital Affiliations

Sunrise Hospital and Medical CenterLas Vegas, Nevada
University Medical CenterLas Vegas, Nevada
St. Rose Dominican Hospitals - San Martin CampusLas Vegas, Nevada
St. Rose Dominican Hospitals - Rose de Lima CampusHenderson, Nevada
Spring Valley Hospital Medical CenterLas Vegas, Nevada
MountainView HospitalLas Vegas, Nevada
Dominican HospitalSanta Cruz, California