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Nicole Simone, MD, Radiation Oncology, Philadelphia, PA

Nicole L Simone MD

Breast Cancer


Professor and Vice Chair of Research, Faculty Affairs, Radiation Oncology, SKCCC Associate Director, Cancer Research Education and Training, Director, Breast Radiation Oncology, Thomas Jefferson University

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  • 111 S. 11th StreetBodine Center For Cancer TreatmentPhiladelphia, PA 19107

  • Phone+1 215-955-6702

  • Fax+1 215-955-5331

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Summary

  • Dr. Nicole Simone is the Margaret Q. Landenberger Professor and Vice Chair of Research and Faculty Development of Radiation Oncology, Associate Director of Cancer Research Training and Education at the Sidney Kimmel Cancer Center at Jefferson Health, and radiation lead for the Jefferson Breast Care Center. She received her undergraduate degree in Bioengineering from the University of Pennsylvania, her MD from Rutgers – New Jersey Medical School and did her radiation oncology training at the National Cancer Institute. She stayed on as staff at the National Cancer Institute where she investigated the long term toxicity caused by cancer treatment. Since that time, she has been a Physician-Scientist at Thomas Jefferson University. Her NCI funded laboratory focuses on how caloric restriction, or a reduction in overall calories can augment the response of chemotherapy and radiation to inhibit tumor growth and metastases while improving survival in breast, prostate and lung cancer models. She incorporates the knowledge gained in the laboratory directly to patients and currently has 2 open clinical trials using diet for breast cancer, and brain metastases. She has authored over 100 research publications, sits on many national review committees, is a Councilor at Radiation Research Society, Chair of the Scientific Education Committee in ASTRO, Co-Chair of the Curriculum committee for CABTRAC, and serves on the Physician Leadership Committee for the American Association of Cancer Institutes. Her long term goal is to find creative ways to ensure each cancer patient has access to nutritional counseling.

Education & Training

  • National Capital Consortium
    National Capital ConsortiumResidency, Radiation Oncology, 2004 - 2008
  • Rutgers Health/New Jersey Medical School
    Rutgers Health/New Jersey Medical SchoolInternship, Internal Medicine, 2003 - 2004
  • Rutgers New Jersey Medical School
    Rutgers New Jersey Medical SchoolClass of 2003

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 2010 - 2026
  • NJ State Medical License
    NJ State Medical License 2017 - 2021
  • MD State Medical License
    MD State Medical License 2004 - 2011
  • Radiation Oncology
    American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

  • CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2013
  • CMS Meaningful Use Stage 1 Certification MOSAIQ EMR, Elekta, 2012

Clinical Trials

Publications & Presentations

PubMed

Press Mentions

  • Nutritional Interventions Have Potential to Improve Cancer Outcomes
    Nutritional Interventions Have Potential to Improve Cancer OutcomesApril 15th, 2025
  • Low-Calorie Diet Helps Prevent Aggressive Breast Cancer from Spreading
    Low-Calorie Diet Helps Prevent Aggressive Breast Cancer from SpreadingMay 28th, 2014
  • Fighting Cancer with Dietary Changes
    Fighting Cancer with Dietary ChangesMay 26th, 2014
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Grant Support

  • Radiation Oncology-Biology Integration Network on Oligometastasis (ROBIN OligoMET) CenterUNIVERSITY OF MARYLAND BALTIMORE2022–2027
  • Radiation Oncology-Biology Integration Network on Oligometastasis (ROBIN OligoMET) CenterUNIVERSITY OF MARYLAND BALTIMORE2022–2027
  • Radiation Oncology-Biology Integration Network on Oligometastasis (ROBIN OligoMET) CenterUNIVERSITY OF MARYLAND BALTIMORE2022–2027
  • Mechanism of lung cancer resistance to tyrosine kinase inhibitor and radiation treatmentsTHOMAS JEFFERSON UNIVERSITY2018–2025
  • (11) Diet Modification to Augment Radiation for Breast Cancer Brain MetastasesTHOMAS JEFFERSON UNIVERSITY2018–2025
  • Underlying Cause Of Radiation-Induced FibrosisNational Cancer Institute2010–2011
  • Mechanism Of Radiation Affects On MicrornaNational Cancer Institute2010–2011
  • Underlying Cause Of Radiation-Induced FibrosisDivision Of Basic Sciences - Nci2009
  • Mechanism Of Radiation Affects On MicrornaDivision Of Basic Sciences - Nci2009
  • Underlying Cause Of Radiation-Induced FibrosisNational Cancer Institute2008

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