NikeBeaubierMD

Pathology • Chicago, IL

Molecular Genetics, Anatomic Pathology, Clinical Pathology

Instructor in Pathology

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Office
251 E Huron St
Feinberg 7-220
Chicago, IL 60611
Phone+1 312-926-6692
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Education & Training

New York Presbyterian Hospital (Cornell Campus)Fellowship, Molecular Genetic Pathology, 2011 - 2012
New York Presbyterian Hospital (Cornell Campus)Residency, Pathology-Anatomic and Clinical, 2007 - 2010
Columbia University Vagelos College of Physicians and SurgeonsClass of 2007

Certifications & Licensure

IL State Medical License 2012 - 2026
NY State Medical License 2010 - 2025
CA State Medical License 2016 - 2024
MD State Medical License 2017 - 2022
IN State Medical License 2018 - 2021
American Board of Pathology Pathology - Anatomic
American Board of Pathology Pathology - Molecular Genetic

Publications & Presentations

PubMed

Development and validation of a deep learning-based microsatellite instability predictor from prostate cancer whole-slide images.
Qiyuan Hu, Abbas A Rizvi, Geoffery Schau, Kshitij Ingale, Yoni Muller, Rachel Baits, Sebastian Pretzer, Aïcha BenTaieb, Abigail Gordhamer, Roberto Nussenzveig, Adam Co...> ;NPJ Precision Oncology. 2024 Apr 9
1 citations
Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry an...
Minoru Miyashita, Joshua S K Bell, Stephane Wenric, Ezgi Karaesmen, Brooke Rhead, Matthew Kase, Kristiyana Kaneva, Francisco M De La Vega, Yonglan Zheng, Toshio F Yosh...> ;Breast Cancer Research. 2023 May 25
6 citations
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin.
Jackson Michuda, Alessandra Breschi, Joshuah Kapilivsky, Kabir Manghnani, Calvin McCarter, Adam J Hockenberry, Brittany Mineo, Catherine Igartua, Joel T Dudley, Martin...> ;Molecular Diagnosis & Therapy. 2023 Jul 1
6 citations
Longitudinal Shifts of Solid Tumor and Liquid Biopsy Sequencing Concordance in Metastatic Breast Cancer.
Minetta C Liu, Matthew MacKay, Matthew Kase, Aneta Piwowarczyk, Christine Lo, Jeff Schaeffer, Justin D Finkle, Christopher E Mason, Nike Beaubier, Kimberly L Blackwell...> ;JCO Precision Oncology. 2022 Jun 1
18 citations
Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort.
Benjamin D Leibowitz, Bonnie V Dougherty, Joshua S K Bell, Joshuah Kapilivsky, Jackson Michuda, Andrew J Sedgewick, Wesley A Munson, Tushar A Chandra, Jonathan R Dry, ...> ;BMC Cancer. 2022 May 28
15 citations
Homologous Recombination Deficiency: Concepts, Definitions, and Assays.
Mark D Stewart, Diana Merino Vega, Rebecca C Arend, Jonathan F Baden, Olena Barbash, Nike Beaubier, Grace Collins, Tim French, Negar Ghahramani, Patsy Hinson, Petar Je...> ;The Oncologist. 2022 Mar 11
15 citations
Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA.
Justin D. Finkle, Hala Boulos, Terri M. Driessen, Christine Lo, Richard A. Blidner, Ashraf T. Hafez, Aly A. Khan, Ariane Lozac’hmeur, Kelly E. McKinnon, Jason Perera, ...> ;NPJ Precision Oncology. 2021 Jul 2
80 citations
Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States.
Tara Alpert, Anderson F. Brito, Erica Lasek-Nesselquist, Jessica E. Rothman, Andrew L Valesano, Matthew MacKay, Mary E. Petrone, Mallery I. Breban, Anne E. Watkins, Ch...> ;Cell. 2021 May 13
11 citations
Early introductions and community transmission of SARS-CoV-2 variant B.1.1.7 in the United States
Tara Alpert, Erica Lasek-Nesselquist, Anderson F. Brito, Andrew L Valesano, Jessica E. Rothman, Matthew MacKay, Mary E. Petrone, Mallery I. Breban, Anne E. Watkins, Ch...> ;Medrxiv. 2021 Feb 12
71 citations
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.
Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. V...> ;Nature Communications. 2021 Jan 13
6 citations
Real-world Evidence of Diagnostic Testing and Treatment Patterns in US Patients With Breast Cancer With Implications for Treatment Biomarkers From RNA Sequencing Data.
Louis E. Fernandes, Caroline G. Epstein, Alexandria M. Bobe, Joshua S.K. Bell, Martin C. Stumpe, Michael E. Salazar, Ameen A. Salahudeen, Ruth A. Pe Benito, Calvin McC...> ;Clinical Breast Cancer. 2021 Aug 1
50 citations
Integrating Next-Generation Sequencing with Morphology Improves Prognostic and Biologic Classification of Spitz Neoplasms
Victor L. Quan, Bin Zhang, Yongzhan Zhang, Lauren S. Mohan, Katherine Shi, Annette Wagner, Lacey Kruse, Timothy Taxter, Nike Beaubier, Kevin P. White, Lihua Zou, Pedra...> ;The Journal of Investigative Dermatology. 2020 Aug 1
13 citations
Molecular analysis of atypical deep penetrating nevus progressing to melanoma.
Maria Cristina Isales, Ayesha U. Khan, Bin Zhang, Elsy V. Compres, Daniel Kim, Timothy L. Tan, Nike Beaubier, Pedram Gerami> ;Journal of Cutaneous Pathology. 2020 Jul 6
26 citations
Tumor Mutational Burden From Tumor-Only Sequencing Compared With Germline Subtraction From Paired Tumor and Normal Specimens.
Kaushal Parikh, Robert Huether, Kevin P. White, Derick Hoskinson, Nike Beaubier, Haidong Dong, Alex A. Adjei, Aaron S. Mansfield> ;JAMA Network Open. 2020 Feb 5
Retrospective Cohort: Genomic Differences Between Pigmented Spindle Cell Nevi of Reed and Reed-Like Melanomas.
Lauren S. Mohan, Ayesha U. Khan, Bin Zhang, Victor L. Quan, Katherine Shi, Maria Cristina Isales, Pedram Yazdan, Yongzhan Zhang, Nike Beaubier, Timothy Taxter, Elsy V....> ;The American Journal of Dermatopathology. 2020 Jan 29
91 citations
Integrated genomic profiling expands clinical options for patients with cancer.
Nike Beaubier, Martin Bontrager, Robert Huether, Catherine Igartua, Denise Lau, Robert Tell, Alexandria M. Bobe, Stephen Bush, Alan L. Chang, Derick Hoskinson, Aly A. ...> ;Nature Biotechnology. 2019 Sep 30
21 citations
Distinct Genomic Features in a Retrospective Cohort of Mucosal, Acral and Vulvovaginal Melanomas.
Katherine Shi, Bin Zhang, Betty Y. Kong, Yongzhan Zhang, Catherine Igartua, Lauren S. Mohan, Victor L. Quan, Maria Cristina Isales, Nike Beaubier, Timothy Taxter, Kevi...> ;Journal of the American Academy of Dermatology. 2019 Jul 12
39 citations
Activating Structural Alterations in MAPK Genes Are Distinct Genetic Drivers in a Unique Subgroup Of Spitzoid Neoplasms
Victor L. Quan, Bin Zhang, Lauren S. Mohan, Katherine Shi, Maria Cristina Isales, Timothy Taxter, Nike Beaubier, Kevin P. White, Pedram Gerami, Elnaz Panah> ;The American Journal of Surgical Pathology. 2019 Apr 1
40 citations
Distinct Genomic Patterns in Pigmented Epithelioid Melanocytoma: A Molecular and Histologic Analysis of 16 Cases.
Maria Cristina Isales, Lauren S. Mohan, Victor L. Quan, Erin M. Garfield, Bin Zhang, Katherine Shi, Nicoleta C. Arva, Nike Beaubier, Pedram Yazdan, Kevin P. White, Tim...> ;The American Journal of Surgical Pathology. 2019 Apr 1
103 citations
Clinical validation of the tempus xT next-generation targeted oncology sequencing assay.
Nike Beaubier, Robert Tell, Denise Lau, Jerod Parsons, Stephen Bush, Jason Perera, Shelly Sorrells, Timothy Baker, Alan Chang, Jackson Michuda, Catherine Iguartua, She...> ;Oncotarget. 2019 Mar 22
58 citations
Multi-field-of-view deep learning model predicts nonsmall cell lung cancer programmed death-ligand 1 status from whole-slide hematoxylin and eosin images
Lingdao Sha, Boleslaw Osinski, Irvin Ho, Timothy L. Tan, Caleb Willis, Hannah Weiss, Nike Beaubier, Brett Mahon, Tim Taxter, Stephen S.F. Yip> ;Journal of Pathology Informatics. 2019 Jan 1
46 citations
Genomic Fusions in Pigmented Spindle Cell Nevus of Reed.
Timothy VandenBoom, Victor L. Quan, Bin Zhang, Erin M. Garfield, Betty Y. Kong, Maria Cristina Isales, Catherine Igartua, Timothy Taxter, Nike Beaubier, Kevin P. White...> ;The American Journal of Surgical Pathology. 2018 Aug 1
455 citations
Recurrent glioblastoma treated with recombinant poliovirus
Annick Desjardins, Matthias Gromeier, James E. Herndon, Nike Beaubier, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea Muscat, Smita ...> ;The New England Journal of Medicine. 2018 Jun 26
34 citations
Clinical validation of the Tempus xO assay.
Nike Beaubier, Robert Tell, Robert Huether, Martin Bontrager, Stephen Bush, Jerod Parsons, Kaanan P. Shah, Timothy Baker, Gene Selkov, Tim Taxter, Amber Thomas, Sam Be...> ;Oncotarget. 2018 May 25
93 citations
Concordance of Genomic Alterations by Next-Generation Sequencing in Tumor Tissue versus Circulating Tumor DNA in Breast Cancer.
Young Kwang Chae, Andrew M. Davis, Sarika Jain, Cesar A. Santa-Maria, Lisa Flaum, Nike Beaubier, Leonidas C. Platanias, William J. Gradishar, Francis J. Giles, Massimo...> ;Molecular Cancer Therapeutics. 2017 Jul 1
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Hospital Affiliations

Northwestern Memorial HospitalChicago, Illinois