NikhilShashikantJoshiMD

Cardiology • Sherman, TX

Interventional Cardiology, Peripheral Endovascular Interventional Cardiology, Non-Invasive Cardiology

Physician

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Office
2800 N Sam Rayburn Fwy
Sherman, TX 75090
Phone+1 903-201-6000

Fax+1 877-915-7181
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Education & Training

Texas A&M College of Medicine-Scott and White Medical Center (Temple)Fellowship, Interventional Cardiology, 2007 - 2008
University of Texas Health Science Center San Antonio Joe and Teresa Lozano Long School of MedicineFellowship, Cardiovascular Disease, 2004 - 2007
University of Texas Health Science Center San Antonio Joe and Teresa Lozano Long School of MedicineResidency, Internal Medicine, 2001 - 2004
Wayne State University School of MedicineClass of 2001

Certifications & Licensure

TX State Medical License 2004 - 2025
OK State Medical License 2023 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Interventional Cardiology

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Publications & Presentations

PubMed

19 citations
Inducible de novo expression of neoantigens in tumor cells and mice
, , , , , , , , , , , , , , , , , , , > ;Nature Biotechnology. 2021 Jan 1
39 citations
Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation.
Leah Marie Schmidt, Banu Eskiocak, Ryan Kohn, Celeste Dang, Nikhil S. Joshi, Michel DuPage, Da-Yae Lee, Tyler Jacks> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Aug 27
57 citations
Incidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: A systematic review and meta-analysis
John George, Divyansh Bajaj, Kesavan Sankaramangalam, Jin Woo (Gene) Yoo, Nikhil S. Joshi, Scott N. Gettinger, Christina Price, James J. Farrell> ;Pancreatology. 2019 Jun 1
44 citations
The American Brachytherapy Society consensus statement on intraoperative radiation therapy.
Martin C. Tom, Nikhil S. Joshi, Frank A. Vicini, Albert J. Chang, Theodore S. Hong, Timothy N. Showalter, Samuel T. Chao, Suzanne L. Wolden, Abraham J. Wu, Douglas Mar...> ;Brachytherapy. 2019 May 1
23 citations
Treg cell IL-10 and IL-35 exhaust CD8+ T cells in tumors.
Martina Damo, Nikhil S. Joshi> ;Nature Immunology. 2019 Jun 1
Lineage Specifiers in Lung Cancer Are Ahead of Their TIME.
Kelli A. Connolly, Brittany Fitzgerald, Nikhil S. Joshi> ;Immunity. 2018 Oct 16
3 citations
Investigating Tumor-Associated Tertiary Lymphoid Structures in Murine Lung Adenocarcinoma.
Kelli A. Connolly, Mursal Nader, Nikhil S. Joshi> ;Methods in Molecular Biology. 2018 Jan 1
213 citations
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
Tuomas Tammela, Francisco J. Sánchez-Rivera, Naniye Malli Cetinbas, Katherine Wu, Nikhil S. Joshi, Katja Helenius, Yoona K Park, Roxana Azimi, Natanya R. Kerper, R. Al...> ;Nature. 2017 May 10
21 citations
Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors.
Gang Xin, David M. Schauder, Weiqing Jing, Aimin Jiang, Nikhil S. Joshi, Bryon D. Johnson, Weiguo Cui> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jan 24
18 citations
NK Cell Responses Redefine Immunological Memory.
Nicholas M. Adams, Timothy E. O’Sullivan, Clair D. Geary, Jenny M. Karo, Robert A. Amezquita, Nikhil S. Joshi, Susan M. Kaech, Joseph C. Sun> ;Journal of Immunology. 2016 Oct 15
39 citations
A Modular Assembly Platform for Rapid Generation of DNA Constructs
Elliot H. Akama-Garren, Nikhil S. Joshi, Tuomas Tammela, Gregory P. Chang, Bethany L. Wagner, Da-Yae Lee, William M. Rideout, Thales Papagiannakopoulos, Wen Xue, Tyler...> ;Scientific Reports. 2016 Feb 18
178 citations
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection
Claudia X. Dominguez, Robert A. Amezquita, Tianxia Guan, Heather D. Marshall, Nikhil S. Joshi, Steven H. Kleinstein, Susan M. Kaech> ;The Journal of Experimental Medicine. 2015 Nov 16
309 citations
Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses
Nikhil S. Joshi, Elliot H. Akama-Garren, Yisi Lu, Da-Yae Lee, Gregory P. Chang, Amy Li, Michel DuPage, Tuomas Tammela, Natanya R. Kerper, Anna F. Farago, Rebecca Robbi...> ;Immunity. 2015 Sep 15
Development and characterization of Haemophilus influenzae type b conjugate vaccine prepared using different polysaccharide chain lengths.
Rana R, Dalal J, Singh D, Kumar N, Hanif S, Joshi N, Chhikara MK> ;Vaccine. 2015-05-28
277 citations
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
Francisco J. Sánchez-Rivera, Thales Papagiannakopoulos, Rodrigo Romero, Tuomas Tammela, Matthew R. Bauer, Arjun Bhutkar, Nikhil S. Joshi, Lakshmipriya Subbaraj, Roderi...> ;Nature. 2014 Dec 18
520 citations
CRISPR-mediated direct mutation of cancer genes in the mouse liver
Wen-Bin Xue, Sidi Chen, Hao Yin, Tuomas Tammela, Thales Papagiannakopoulos, Nikhil S. Joshi, Wenxin Cai, Gillian R. Yang, Roderick T. Bronson, Denise G. Crowley, Feng ...> ;Nature. 2014 Oct 16
47 citations
TLR4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A Differentially Regulate Effector and Memory CD8+ T Cell Differentiation
Weiguo Cui, Nikhil S. Joshi, Ying Liu, Hailong Meng, Steven H. Kleinstein, Susan M. Kaech> ;Journal of Immunology. 2014 May 1
Koch Institute Symposium on Cancer Immunology and Immunotherapy
Adam Drake, Nikhil S. Joshi, Gregory L. Szeto, Eric F. Zhu, Herman N. Eisen, Darrell J. Irvine> ;Cancer Immunology Research. 2013 Oct 1
3 citations
Guilty by Association
Nikhil S. Joshi, Tyler Jacks> ;Science. 2013 Mar 8
69 citations
Increased Numbers of Preexisting Memory CD8 T Cells and Decreased T-bet Expression Can Restrain Terminal Differentiation of Secondary Effector and Memory CD8 T Cells
Nikhil S. Joshi, Weiguo Cui, Claudia X. Dominguez, Jonathan H. Chen, Timothy W. Hand, Susan M. Kaech> ;Journal of Immunology. 2011 Oct 15
85 citations
Differential Localization of Effector and Memory CD8 T Cell Subsets in Lymphoid Organs during Acute Viral Infection
Yong Woo Jung, Rachel L. Rutishauser, Nikhil S. Joshi, Ann M. Haberman, Susan M. Kaech> ;Journal of Immunology. 2010 Nov 1
161 citations
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
Timothy W. Hand, Weiguo Cui, Yong Woo Jung, Esen Sefik, Nikhil S. Joshi, Anmol Chandele, Ying Liu, Susan M. Kaech> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Sep 21
42 citations
Viperin Is Highly Induced in Neutrophils and Macrophages during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection
Ella R. Hinson, Nikhil S. Joshi, Jonathan H. Chen, Christoph Rahner, Yong Woo Jung, Xiuyan Wang, Susan M. Kaech, Peter Cresswell> ;Journal of Immunology. 2010 May 15
101 citations
Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.
Weiguo Cui, Nikhil S. Joshi, Aimin Jiang, Susan M. Kaech> ;Vaccine. 2009 Mar 26
69 citations
Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.
Anmol Chandele, Nikhil S. Joshi, Jinfang Zhu, William E. Paul, Warren J. Leonard, Susan M. Kaech> ;Journal of Immunology. 2008 Apr 15
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