Nils Axel Loewen MD PhD

PubMed

• VEGF-A-induced changes in distal outflow tract structure and function.
  Jannis Oltmann, Mark Morell, Mohamad Dakroub, Raoul Verma-Fuehring, Jost Hillenkamp
  Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2024-02-01
• Coarsened Exact Matching of Excisional to Plasma-ablativeTrabeculectomy.
  Mohamad Dakroub, Raoul Verma-Fuehring, Alicja Strzalkowska, Jost Hillenkamp, Yousef Al Yousef
  Journal of Current Glaucoma Practice. 2023-05-25
• 1 citations
  Tissue-engineered anterior segment eye cultures demonstrate hallmarks of conventional organ culture.
  Susannah Waxman, Alicja Strzalkowska, Chao Wang, Ralitsa Loewen, Yalong Dang
  Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2023-05-01

Journal Articles

• Structure–Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide  
  Nils A Loewen, Ralitsa T Loewen, Investigative Ophthalmology and Visual Science
• High-Resolution, Three-Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes  
  Ralitsa T Loewen, Nils A Loewen, Investigative Ophthalmology and Visual Science
• Clinical Results of Ab Interno Trabeculotomy Using the Trabectome in Patients with Pigmentary Glaucoma compared to Primar Open Angle Glaucoma  
  Akil H, Chopra V, Huang A, Loewen N, Noguchi J, Francis BA, Clin Experiment Ophthalmol, 1/6/2016
• NA Porcine Anterior Segment Perfusion and Transduction Model with Direct Visualization of A the Trabecular Meshwork  
  Loewen RT, Roy P, Park DB, Jensen A, Scott G, Cohen­Karni D, Fautsch MP, Schuman JS, Loewen NA, Invest Ophthalmol Vis Sci, 1/1/2016
• Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier­Domain Optical Coherence Tomography  
  Zhang X, Loewen N, Tan O, Greenfield DS, Schuman JS, Varma R, Huang D; Advanced Imaging for Glaucoma Study Group, Am J Ophthalmol, 1/1/2016
• Coarsened Exact Matching of Phaco­Trabectome to Trabectome in Phakic Patients: Lack of Additional Pressure Reduction from Phacoemulsification  
  Parikh HA, Bussel II, Schuman JS, Brown EN, Loewen NA, PLoS One, 1/1/2016
• Randomized Controlled Comparison of Titanium­Sapphire versus Standard Q­switched Nd:YAG Laser Trabeculoplasty  
  Kaplowitz, K., Wang, S., Bilonick, R., Oatts, J.T., Grippo, T., Loewen, N.A., J Glaucoma, 1/28/2015
• Trabectome Patient Selection, Preparation, Technique, Management, and Outcomes  
  Hardik A. Parikh, Pritha Roy, Amar Dhaliwal, Kevin B. Kaplowitz, Nils A. Loewen, US Ophthalmic Review, 1/1/2015
• Effect of alpha­2­agonist premedication on intraocular pressure after selective laser trabeculoplasty  
  Oatts JT, Wang X, Loewen NA, Indian J Ophthalmol, 1/1/2015
• Ab interno trabeculectomy demonstrates positive outcomes, even in patients with narrow angles  
  Parikh H., Bussel I., Loewen., Ophthalmology Times Europe, 1/1/2015
• Review and Meta­Analysis of Ab­Interno Trabeculectomy Outcomes  
  Kaplowitz K, Bussel I.I., Honkanen R., Schuman J.S., Loewen N.A., Br J Ophthalmol, 1/1/2015
• Combining Z measurements from three anatomical areas for glaucoma diagnosis using Fourier­domain optical coherence tomography  
  Loewen, N.A.,hang, X, Tan O., Greenfield D.S., Schuman J.S., Varma R., Huang D, Br J Ophthalmol, 1/1/2015
• Time Spent in Lateral Sleep Position and Asymmetry in Glaucoma  
  Kaplowitz K, Blizzard S, Blizzard DJ, Nwogu E, Hamill CE, Weinreb RN, Mohsenin V,Loewen NA, Invest Ophthalmol Vis Sci, 1/1/2015
• O utflow tract ablation using a conditionally cytotoxic feline immunodeficiency viral vector  
  Zhang Z, Dhaliwal AS, Tseng H, Kim JD, Schuman JS, Weinreb RN, Lo ewen NA, Invest Ophthalmol Vis Sci, 1/1/2014
• Trabectome Study Group Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening  
  Bussel II, Kaplowitz K, Schuman JS, Loewen NA, Br J Ophthalmol, 1/1/2014
• Clinical results of ab interno trabeculotomy using the Trabectome for open­angle glaucoma: the Mayo clinic series in Rochester, Minnesota  
  Minckler D, Mosaed S, Francis B, Loewen N, Weinreb RN, Am J Ophthalmol, 1/1/2014
• Advanced Imaging for Glaucoma Study Group Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter­Site Comparison  
  Le PV, Zhang X, Francis BA, Varma R, Greenfield DS, Schuman JS, Loewen N, Huang D, Am J Ophthalmol, 1/1/2014
• Trabectome: Ab Interno Trabeculectomy  
  Polat J., Loewen N.A., EyeWiki, 1/1/2014
• Treatment Pathways in Glaucoma and Cataract Care  
  Brown E., Loewen N.A., Ocular Surgery News, 1/1/2014
• Large referral center explores efficacy of Trabectome­mediated ab interno trabeculectomy  
  Loewen N.A., Ocular Surgery News, 1/1/2014
• The Right Microscope for Demanding Surgery  
  Lagouros E.,Loewen N.A., Ocular Surgery News, 1/1/2014
• Expanding Indications of Ab­Interno Trabeculectomy  
  Kaplowitz K., Bussel I., Schuman J.S., Loewen N.A., Ophthalmology Times Europe, 1/1/2014
• iStent Surgery as an Option for Mild to Moderate Glaucoma  
  K Kaplowitz, A Abazari, R Honkanen and Loewen N, Expert Rev Ophthalmol, 1/18/2013
• Cl inicopathologic Correlation of Disc and Peripapillary Region Using SD­OCT  
  Sigler EJ, Mascarenhas KG, Tsai JC, Lo ewen NA, Optom Vis Sci, 1/1/2013
• Opinion Piece: We Must Do Better, Acquire Excellent MIGS Skills  
  Loewen N.A., International Glaucoma Review, 1/1/2013
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Books/Book Chapters

• Minimally Invasive Glaucoma Surgery: the Science and the Practice. 
  Chapter: Chapter 7: Trabeculectomy by Internal Approach: Trabectome. 
  Kaplowitz K., Bussel I., Loewen N.A.Editors: Francis B. & Sarkisian S.Thieme2015
• Trabeculectomy for Secondary Glaucoma or as a Secondary Procedure 
  Chapter: Trabectome­Mediated Ab Interno 
  Page 51 - 73Kaplowitz, K., Loewen, N. A.Editors: Aref, A. A. & Varma, R..Springer2014
• Surgical Innovations in Glaucoma. 
  Chapter: Minimally Invasive Glaucoma Surgery: Trabeculectomy Ab Interno. 
  Page 175 - 186Kaplowitz K., Loewen N.A.Editors: Samples, John R. & Ahmed, Iqbal Ike K..Springer, New York, NY2014
• The Glaucoma Book: A Practical, Evidence­Based Approach to Patient Care. 
  Chapter: Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma 
  Page 35 - 50Loewen N.A., Tanna A.P.Editors: Schacknow PN, Samples JR.SpringerEdition 2nd,2013
• Ophthalmology: Expert Consult: Online and Print. 
  Chapter: Minimally Invasive and Nonpenetrating Glaucoma Surgery 
  Page 1133 - 1146Kaplowitz K., Bussel I., Loewen N.A.Editors: Yanoff, M. & Duker, J. S..Elsevier­Health Sciences Division2013
• The Glaucoma Book: A Practical, Evidence­Based Approach to Patient Care. 
  Chapter: Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma. 
  Loewen N.A., Tanna A.P.Editors: Schacknow PN, Samples JR.SpringerEdition 1st,2010
• Gene Transfer: A Laboratory Manual. 
  Chapter: Production and Use of Feline Immunodeficiency Virus (FIV)­Based Lentiviral Vectors 
  Page 57 - 73Saenz D.T., Barraza R., Loewen N., Teo W., Poeschla E.Editors: Rossi, J., Friedman, T..Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY2005
• Lentiviral gene engineering protocols. 
  Chapter: FIV Vectors. 
  Page 251 - 273Loewen N., Barraza R., Whitwam T., Saenz, D.T., Kemler I., Poeschla E.M.Editors: M. Federico.Humana Press2003
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Abstracts/Posters

• Outflow Modification.
  Loewen N, Nantucket Glaucoma Meeting, 1/1/2015
• Semi­Quantitative Measurements and Live Outflow Imaging In Porcine Eyes.
  Loewen R., Brown E., Sengupta P., Kola S., Schuman J.S., Loewen N.A., Vision Restoration Conference, University of Pittsburgh, 1/1/2015
• Matched Comparison of Phaco­Trabectome to Trabectome in Phakic Patients.
  Hardik Parikh,BS, Igor I. Bussel,MD, Joel S. Schuman,MD, Nils A. Loewen MD, PhD, American Glaucoma Society Meeting, 1/1/2015
• Trabectome Surgery Calculator: Additive Effect from Combining Phacoemulsification with Trabectome in a Matched Comparison to Sequential Trabectome in Pseudophakic Eyes.
  Neiweem, A., Bussel, I.I., Schuman, J.S., Brown, E.N., Loewen, N.A., American Glaucoma Society Meeting, 1/1/2015
• Stratification of Results of Trabectome with Phacoemulsification by Glaucoma Severity: Larger IOP Reduction in More Advanced Glaucoma.
  Pritha Roy, MD, Ralitsa Loewen, MD, Hardik Parikh, BS, Yalong Dang, MD, Joel Schuman, MD, Nils Loewen, MD, PhD, American Glaucoma Society Meeting, 1/1/2015
• Impact of Relative Glaucoma Severity on Results of Trabectome Surgery.
  Ralitsa Loewen, Pritha Roy, Hardik Parikh, Yalong Dang, Joel Schuman, Nils Loewen, American Glaucoma Society Meeting, 1/1/2015
• Trabectome­Mediated Ab Interno Trabeculectomy for Steroid­Induced Glaucoma.
  Yalong Dang, Hardik Parikh, Pritha Roy, Igor Bussel, Ralitsa Loewen, Nils Loewen, American Glaucoma Society Meeting, 1/1/2015
• Trabecular Meshwork Engineering and Live Tracking in Perfused Porcine Anterior Segments.
  Loewen R., Sengupta P., Cohen­Karni D., Kola S., Ladley R., Dhaliwal A., Mandell J., Espandar L., Schuman J.S., Loewen N.A., Association for Research in Vision and Ophthalmology, 1/1/2015
• Live Outflow Imaging In Porcine Eyes.
  Loewen R., Sengupta P., Kola S., Schuman J.S., Loewen N.A., Association for Research in Vision and Ophthalmology, 1/1/2015
• Comparison of Trabectome Ab Interno Trabeculectomy to Baerveldt Glaucoma Implants using Propensity Score Matching.
  Steven Wang, Eric Brown, Kevin Kaplowitz, Sushma Kola, Julia Polat, Joel S. Schuman, Nils A. Loewen, Association for Research in Vision and Ophthalmology, 1/1/2015
• Case­Matched Intraocular Pressure Results of Trabectome Ab Interno Trabeculectomy versus Ahmed Glaucoma Implant.
  Sushma Kola, Eric Brown, Kevin Kaplowitz, Steven Wang, Julia Polat, Joel S. Schuman, Nils A. Loewen, Association for Research in Vision and Ophthalmology, 1/1/2015
• Meta­Analysis of Trabeculectomy Ab­Interno Outcomes.
  Loewen N.A., Bussel I, Kaplowitz K., American Glaucoma Society Meeting, 1/1/2015
• The Utility of iPhone­based Imaging for Tele­ophthalmology in a Triage Capacity for Emergency Room Consultations.
  John E. Legarreta, Ian P. Conner, Nils A. Loewen, Kimberly V. Miller, Jeremy Wingard, Association for Research in Vision and Ophthalmology, 1/1/2014
• Trabectome Only Surgery.
  Constance Okeke, Eydie Miller­Ellis, Nils Loewen, American Glaucoma Society Meeting, Washington, DC, 1/1/2014
• Degree of Angle Opening not Related to Outcome in Phaco­Trabectome or Trabectome Surgery.
  Kaplowitz K., Bussel I., Loewen N.A., American Glaucoma Society Meeting, Washington, DC, 1/1/2014
• Trabectome Ab Interno Trabeculectomy in Highly Complex Glaucomas.
  Loewen R., Lagouros E., Loewen N.A., Association for Research in Vision and Ophthalmology, 1/1/2014
• Comparison of Trabectome Ab Interno Trabeculectomy to Baerveldt and Ahmed Glaucoma Implants.
  Sushma K., Lagouros, E, Kaplowitz, K, Davis R., Schuman J.S., Loewen N.A., Association for Research in Vision and Ophthalmology, 1/1/2014
• Predicting Glaucomatous Visual Field Damage With Fourier Domain OCT in the Advanced Imaging for Glaucoma Study.
  Xinbo Zhang , Nils A Loewen, Ou Tan PHD, Brian A Francis MD, Rohit Varma MD MPH, David S Greenfield MD, Joel S Schuman MD, American Academy of Ophthalmology, Chicago, IL, 1/1/2014
• Subgroup Analysis of Trabectome after Failed Trabeculectomy.
  Bussel I., Loewen N.A., Deutsche Ophthalmologische Gesellschaft Meeting, Berlin, Germany, 1/1/2013
• Outflow Tract Ablation using a Conditionally Cytotoxic Feline Immunodeficiency Viral Vector.
  Dhaliwal, A, Kim J, Zhang Z, Tseng H, Weinreb R.N., Loewen N.A., Vision Restoration: Regenerative Medicine in Ophthalmology, University of Pittsburgh, PA, 1/1/2013
• Lack of Inflammation in Outflow Tract Ablation using a Conditionally Cytotoxic Feline Immunodeficiency Viral Vector.
  Kim J, Dhaliwal A, Zhang Z, Tseng H, Weinreb R.N., Loewen N.A., Research Retreat Ophthalmology, University of Pittsburgh, 1/1/2013
• Post­Procedure Intraocular Pressure of Titanium­Sapphire Laser Compared to Standard Selective Trabeculoplasty.
  Oatts J., Kaplowitz K., Loewen N.A., American Glaucoma Society, San Francisco, CA, 1/1/2013
• Two Year Results of 180° Trabectome Ablation.
  Kaplowitz K., Chen X., Loewen N.A., American Glaucoma Society, San Francisco, CA, 1/1/2013
• Postoperative Intraocular Pressure After Selective Laser Trabeculoplasty Not Affected by Alpha­2­Agonist Premedication.
  Oatts J., Kaplowitz K., Patel N., Loewen N.A., American Glaucoma Society, New York, NY, 1/1/2012
• In Vitro Biocompatibility Assay of Suprachoroidal Glaucoma Shunts Indicates Vulnerability to Fibrosis In Vivo.
  Tseng H., Zhang Z., Oatts J., Loewen N.A., Albany Medical College Medical Student Investigation Event, Albany Medical College, Albany, NY, 1/1/2012
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Lectures

• Laser Trabeculoplasty as 1st line of treatment for glaucomas with open angle. 
  1/1/2015
• Introduction to Trabectome Surgery: Technique and Outcomes. 
  Sanmenxia, China - 1/1/2015
• Outcomes in Expanded Indications. 
  University of Lanzhou, China - 1/1/2015
• Trabectome Surgery: Techniques and Technology. 
  University of Lanzhou, China - 1/1/2015
• Trabeculoplasty. 
  University of Lanzhou, China - 1/1/2015
• Outflow Engineering. 
  University of Mainz, Germany - 1/1/2015
• Trabectome Surgery: Update on Technique and New Range of Indications. 
  Guangzhou, China - 1/1/2015
• Restoring Outflow. 
  University of Pittsburgh - 1/1/2015
• Ab Interno Trabeculectomy: Techniques and range of Indications. 
  1/1/2015
• Ab Interno Approach to Schlemm's Canal. 
  Chicago, IL - 1/1/2014
• Trabeculoplasty as First Line of Treatment in POAG. 
  Tampa, FL - 1/1/2014
• Bioengineering Outflow. 
  Tampa, FL - 1/1/2014
• Ab Interno Trabeculectomy from Hypertension to Advanced Glaucoma. 
  Tampa, FL - 1/1/2014
• A Conditionally Cytotoxic Viral Vector for Trabecular Meshwork Ablation. 
  1/1/2014
• Glaucoma Surgery. 
  University of Pittsburgh - 1/1/2014
• Towards Outflow Tract Regeneration. 
  University of Pittsburgh - 1/1/2014
• Anterior Chamber Anatomy and Glaucoma. 
  University of Pittsburgh - 1/1/2014
• Phaco­Trabectome Techniques ­ Video. 
  1/1/2013
• Putting Phaco­Trabectome into Perspective. 
  1/1/2013
• Bioengineering of Trabecular Meshwork. 
  University of Pittsburgh, PA - 1/1/2013
• Key Steps in Trabectome Surgery. 
  University of Pittsburgh, School of Medicine - 1/1/2013
• Trabectome Study Group. 1­Year Outcomes for Trabectome after Failed Trabeculectomy. 
  Vancouver, Canada - 1/1/2013
• Ab Interno Trabeculectomy. 
  Vancouver, Canada - 1/1/2013
• Vector­Mediated Trabecular Meshwork Ablation In Vivo. 
  Berlin, Germany - 1/1/2013
• Update on Trabectome Outcomes in POAG and PXG. 
  Berlin, Germany - 1/1/2013
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Other

• Trabectome Surgery: A Minimally­Invasive Glaucoma Procedure. 
  Kaplowitz K., Loewen N.A., Glaucoma Research Foundation
  1/17/2012