NormanL.LehmanMDPhD

PubMed

• Spatially Resolved Microglia/Macrophages in Recurrent Glioblastomas Overexpress Fatty Acid Metabolism and Phagocytic Genes.
  Jonah Daneshmand, SeonYeong Jamie Seo, Dylan A Goodin, Hermann B Frieboes, Joseph Chen, Kavitha Yaddanapudi, Akshitkumar M Mistry, Norman L Lehman, Donald M Miller, Ad...> ;Current Oncology. 2024 Feb 23
• 2 citations
  Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2023 Jan 31
• 1 citations
  The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo.
  Müge Sak, Brian J Williams, Cory T Zumbar, Landon Teer, Mustafa N G Al-Kawaaz, Aastha Kakar, Andrew J Hey, Megan J Wilson, Leslie M Schier, Joseph Chen, Norman L Lehman> ;Cancer Chemotherapy and Pharmacology. 2023 Feb 1
• 3 citations
  Early ependymal tumor with MN1-BEND2 fusion: a mostly cerebral tumor of female children with a good prognosis that is distinct from classical astroblastoma.
  Norman L Lehman> ;Journal of Neuro-Oncology. 2023 Feb 1
• 1 citations
  Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2022 Apr 19
• 1 citations
  Malignant melanotic nerve sheath tumor with PRKAR1A, KMT2C, and GNAQ mutations.
  Merryl Terry, Kristina Wakeman, Brian J Williams, Donald M Miller, Müge Sak, Zied Abdullaev, Marwil C Pacheco, Kenneth Aldape, Norman L Lehman> ;Free Neuropathology. 2022 Jan 1
• Aurora-A kinase is differentially expressed in the nucleus and cytoplasm in normal Müllerian epithelium and benign, borderline and malignant serous ovarian neoplasms.
  Khaled J. Alkhateeb, Jason E. Crane, Muge Sak, Caitlin J. Jorgensen, James P. O’Donnell, Cory T. Zumbar, Jason A. Wozniak, Clarence R. Salazar, Anil V. Parwani, Norman...> ;Diagnostic Pathology. 2021 Oct 27
• 27 citations
  HNRNPA2B1 regulates tamoxifen- and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells.
  Belinda J Petri, Kellianne M. Piell, Gordon C. South Whitt, Ali E. Wilt, Claire C. Poulton, Norman L. Lehman, Brian F. Clem, Matthew A. Nystoriak, Marcin Wysoczynski, ...> ;Cancer Letters. 2021 Oct 10
• 3 citations
  Pituitary carcinomas: review of the current literature and report of atypical case.
  Alexandre B. Todeschini, André Beer-Furlan, Alaa S. Montaser, Ali O. Jamshidi, Luma Ghalib, Jesus A Chavez, Norman L. Lehman, Daniel M. Prevedello> ;British Journal of Neurosurgery. 2020 Sep 2
• 7 citations
  Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.
  Muge Sak, Cory T. Zumbar, Paul D. King, Xiaohui Li, Caroline S. Mifsud, Aisulu Usubalieva, Charles D. Anderson, Hailey M Chesnick, Joseph P. McElroy, Arnab Chakravarti...> ;Journal of Neuro-Oncology. 2019 Apr 22
• 54 citations
  Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorabl...
  Norman L. Lehman, Aisulu Usubalieva, Tong Lin, Sariah Allen, Quynh T. Tran, Bret C. Mobley, Roger E. McLendon, Matthew Schniederjan, Maria Magdalena Georgescu, Marta C...> ;Acta Neuropathologica Communications. 2019 Mar 15
• 38 citations
  PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance
  Luke Russell, Jessica Swanner, Alena Cristina Jaime-Ramirez, Yufeng Wang, Alex Sprague, Yeshavanth Kumar Banasavadi-Siddegowda, Ji Young Yoo, Gina M. Sizemore, Raleigh...> ;Nature Communications. 2018 Nov 27
• 113 citations
  A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
  Rai, K., Anil Korkut, Sobia Zaidi, Rupa S. Kanchi, Shuyun Rao, Nancy R. Gough, Andre Schultz, Xubin Li, Philip L. Lorenzi, Ashton C. Berger, Gordon Robertson, Lawrence...> ;Cell Systems. 2018 Oct 24
• 249 citations
  Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))
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• Multiple lesions of skull and cervical spine: a rare presentation of unicameral bone cysts.
  Kristin Huntoon, Sophia Shaddy, Norman L. Lehman, James B. Elder> ;BMJ Case Reports. 2018 Jul 14
• 558 citations
  Genomic and Functional Approaches to Understanding Cancer Aneuploidy
  Rai, K., Alison M. Taylor, Juliann Shih, Gavin Ha, Galen F. Gao, Xiaoyang Zhang, Ashton C. Berger, Steven E. Schumacher, Chen Wang, Hai Hu, Jianfang Liu, Alexander J. ...> ;Cancer Cell. 2018 Apr 9
• 1273 citations
  Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
  Rai, K., Katherine A Hoadley, Christina Yau, Toshinori Hinoue, Denise M. Wolf, Alexander J. Lazar, Esther Drill, Ronglai Shen, Alison M. Taylor, Andrew D. Cherniack, V...> ;Cell. 2018 Apr 5
• 201 citations
  Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
  Rai, K., Joshua D. Campbell, Christina Yau, Reanne Bowlby, Yuexin Liu, Kevin Brennan, Huihui Fan, Alison M. Taylor, Chen Wang, Vonn Walter, Rehan Akbani, Lauren Averet...> ;Cell Reports. 2018 Apr 3
• 224 citations
  Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
  Rai, K., Franz X. Schaub, Varsha Dhankani, Ashton C. Berger, Mihir Trivedi, Anne B. Richardson, Reid Shaw, Wei Zhao, Xiaoyang Zhang, Andrea Ventura, Yuexin Liu, Donald...> ;Cell Systems. 2018 Mar 28
• 15 citations
  The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells
  Cory T. Zumbar, Aisulu Usubalieva, Paul D. King, Xiaohui Li, Caroline S. Mifsud, Hailey M. Dalton, Muge Sak, Sara Urio, William M. Bryant, Joseph P. McElroy, George Fa...> ;Journal of Neuro-Oncology. 2018 Feb 2
• 46 citations
  Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair.
  Steven T. Sizemore, Manchao Zhang, Ju Hwan Cho, Gina M. Sizemore, Brian Hurwitz, Balveen Kaur, Norman L. Lehman, Michael C. Ostrowski, Pierre A. Robe, Weili Miao, Yins...> ;Cell Research. 2018 Oct 8
• 7 citations
  IgG4-Related Disease: A New Etiology Underlying Diffuse Intracranial Dilating Vasculopathy.
  Evan S. Marlin, David Dornbos, Daniel S. Ikeda, Norman L. Lehman, Ciaran J. Powers> ;World Neurosurgery. 2017 Nov 1
• 9 citations
  Cerebrospinal fluid dissemination of high-grade gliomas following boron neutron capture therapy occurs more frequently in the small cell subtype of IDH1R132H mutation-...
  Natsuko Kondo, Rolf F. Barth, Shin-Ichi Miyatake, Shinji Kawabata, Minoru Suzuki, Koji Ono, Norman L. Lehman> ;Journal of Neuro-Oncology. 2017 May 22
• 7 citations
  Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing’s disease
  Amy Joehlin-Price, Douglas A. Hardesty, Christina A. Arnold, Lawrence S. Kirschner, Daniel M. Prevedello, Norman L. Lehman> ;Diagnostic Pathology. 2017 Apr 18
• 40 citations
  Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children a...
  Norman L. Lehman, Eyas M. Hattab, Bret C. Mobley, Aisulu Usubalieva, Matthew Schniederjan, Roger E. McLendon, Werner Paulus, Elisabeth J. Rushing, Maria Magdalena Geor...> ;Neuro-Oncology. 2017 Jan 1
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