OfraSarid-SegalMD

Psychiatry • Cambridge, MA

Addiction, Forensic Psychiatry

Assistant Clinical Professor, Psychiatry, Tufts Medical Center

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Office
Mount Auburn Hospital
330 Mount Auburn Street
Cambridge, MA 02138
Phone+1 617-499-5054

Fax+1 617-499-5465
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Education & Training

Institute of Living/Hartford HospitalResidency, Psychiatry, 1985 - 1989
Tel Aviv University SacklerClass of 1984

Certifications & Licensure

MA State Medical License 1989 - 2025
American Board of Psychiatry and Neurology Psychiatry
American Board of Psychiatry and Neurology Addiction Psychiatry

Clinical Trials

The Effects of Levetiracetam on Alcohol Dependent Subjects Start of enrollment: 2006 Jan 01
Completed
Phase 4
Transcranial Magnetic Stimulation in Major Depression With EEG and Near Infrared Spectroscopy (NIRS) Monitoring Start of enrollment: 2012 Dec 01
Terminated
Early Phase 1
Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders Start of enrollment: 2012 Jan 01
Terminated

Publications & Presentations

PubMed

8 citations
Payment expectations for research participation among subjects who tell the truth, subjects who conceal information, and subjects who fabricate information
Eric Devine, Clifford M. Knapp, Ofra Sarid-Segal, Sean M. O'Keefe, Cale Wardell, Morgan Baskett, Ashley Pecchia, Katie Ferrell, Domenic A. Ciraulo> ;Contemporary Clinical Trials. 2015 Mar 1
37 citations
Zonisamide, Topiramate, and Levetiracetam: Efficacy and Neuropsychological Effects in Alcohol Use Disorders
Clifford M. Knapp, Domenic A. Ciraulo, Ofra Sarid-Segal, Mark A. Richardson, Eric Devine, Chris C. Streeter, Marlene Oscar-Berman, Caitlin Surprise, Laurie Sickles Col...> ;Journal of Clinical Psychopharmacology. 2015 Feb 1
73 citations
Concealment and fabrication by experienced research subjects.
Eric Devine, Megan E. Waters, Megan A. Putnam, Caitlin Surprise, Katie O’Malley, Courtney Richambault, Rachel Lea Fishman, Clifford M. Knapp, Elissa H. Patterson, Ofra...> ;Clinical Trials. 2013 Jul 18
186 citations
A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence.
Raye Z. Litten, Megan L. Ryan, Joanne B. Fertig, Daniel E. Falk, Bankole A. Johnson, Kelly E. Dunn, Alan I. Green, Helen M. Pettinati, Domenic A. Ciraulo, Ofra Sarid-S...> ;Journal of Addiction Medicine. 2013 Jul 1
35 citations
The Efficacy of Mirtazapine in the Treatment of Cocaine Dependence with Comorbid Depression
Maryam Afshar, Clifford M. Knapp, Ofra Sarid-Segal, Eric Devine, Laurie Sickles Colaneri, Lisa Tozier, Megan E. Waters, Megan A. Putnam, Domenic A. Ciraulo> ;The American Journal of Drug and Alcohol Abuse. 2012 Feb 22
16 citations
Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence.
Clifford M. Knapp, Ofra Sarid-Segal, Mark A. Richardson, Laurie Sickles Colaneri, Maryam Afshar, Eric Devine, Chris C. Streeter, Joanne Piechniczek-Buczek, Domenic A. ...> ;The American Journal of Drug and Alcohol Abuse. 2010 Mar 25
21 citations
The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers.
Ofra Sarid-Segal, Clifford M. Knapp, William L. Burch, Mark A. Richardson, Sean Bahtia, Kimberly DeQuattro, Maryam Afshar, Courtney Richambault, Laurie Sickels, Eric D...> ;The American Journal of Drug and Alcohol Abuse. 2009 Sep 15
135 citations
Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals.
Chris C. Streeter, Devin Blair Terhune, Theodore H. Whitfield, Staci A. Gruber, Ofra Sarid-Segal, Marisa M. Silveri, Golfo K. Tzilos, Maryam Afshar, Elizabeth D. Rouse...> ;Neuropsychopharmacology. 2008 Mar 1
22 citations
The Effects of Levetiracetam on Alcohol Consumption in Alcohol-Dependent Subjects: An Open Label Study
Ofra Sarid-Segal, Joanna Piechniczek-Buczek, Clifford M. Knapp, Maryam Afshar, Eric Devine, Laurie Sickles, Emma Uwodukunda, Courtney Richambault, Jillian Koplow, Dome...> ;The American Journal of Drug and Alcohol Abuse. 2008 Jan 1
27 citations
A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence
Theresa Winhusen, Eugene Somoza, Ofra Sarid-Segal, R. Jeffrey Goldsmith, Judy M. Harrer, Florence S. Coleman, Roberta Kahn, Sabuhi Osman, Juris P. Mezinskis, Shou-Hua ...> ;Drug and Alcohol Dependence. 2007 Dec 1
2 citations
Reduced Plasma Nitric Oxide End Products in Cocaine-dependent Men.
Marc J. Kaufman, Chris C. Streeter, Tanya L. Barros, Ofra Sarid-Segal, Maryam Afshar, Hua Tian, Elizabeth D. Rouse, Karen K. B. Foy, Melanie Brimson, Courtney A. Archa...> ;Journal of Addiction Medicine. 2007 Jun 1
130 citations
Cerebellar gray matter volume correlates with duration of cocaine use in cocaine-dependent subjects.
Minyoung Sim, In Kyoon Lyoo, Chris C. Streeter, Julie Covell, Ofra Sarid-Segal, Domenic A. Ciraulo, Minue J. Kim, Marc J. Kaufman, Deborah A. Yurgelun-Todd, Perry F. R...> ;Neuropsychopharmacology. 2007 Feb 14
47 citations
Pharmacokinetics and Pharmacodynamics of Multiple Sublingual Buprenorphine Tablets in Dose‐Escalation Trials
Domenic A. Ciraulo, Robert Hitzemann, Eugene Somoza, Clifford M. Knapp, John Rotrosen, Ofra Sarid-Segal, Ann Marie Ciraulo, David J. Greenblatt, C. Nora Chiang> ;Journal of Clinical Pharmacology. 2006 Feb 1
27 citations
Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment
Chris C. Streeter, John Hennen, Yong Ke, J. Eric Jensen, Ofra Sarid-Segal, Leanne E. Nassar, Clifford M. Knapp, Angela A. Meyer, Tae Kwak, Perry F. Renshaw, Domenic A....> ;Psychopharmacology. 2005 Aug 2
21 citations
Nefazodone treatment of cocaine dependence with comorbid depressive symptoms.
Domenic A. Ciraulo, Clifford M. Knapp, John Rotrosen, Ofra Sarid-Segal, Ann Marie Ciraulo, Joseph S. LoCastro, David J. Greenblatt, Deborah B. Leiderman> ;Addiction. 2005 Mar 1
41 citations
Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence
Domenic A. Ciraulo, Ofra Sarid-Segal, Clifford M. Knapp, Ann Marie Ciraulo, Joseph S. LoCastro, Daniel A. Bloch, Margaret A. Montgomery, Deborah B. Leiderman, Ahmed El...> ;Addiction. 2005 Mar 1
80 citations
White matter hyperintensities in subjects with cocaine and opiate dependence and healthy comparison subjects.
In Kyoon Lyoo, Chris C. Streeter, Kyung-Heup Ahn, Ho Kyu Lee, Mark H. Pollack, Marisa M. Silveri, Leanne E. Nassar, Jonathan M. Levin, Ofra Sarid-Segal, Domenic A. Cir...> ;Psychiatry Research. 2004 Jul 30
65 citations
Frontal lobe GABA levels in cocaine dependence: a two-dimensional, J-resolved magnetic resonance spectroscopy study.
Yong Ke, Chris C. Streeter, Leanne E. Nassar, Ofra Sarid-Segal, John Hennen, Deborah A. Yurgelun-Todd, Lily A. Awad, Melanie J. Rendall, Staci A. Gruber, Ariel Nason, ...> ;Psychiatry Research. 2004 Apr 30
52 citations
Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects.
Bankole A. Johnson, Stephanie S. O'Malley, Domenic A. Ciraulo, John D. Roache, Robert A. Chambers, Ofra Sarid-Segal, David Couper> ;Journal of Clinical Psychopharmacology. 2003 Jun 1
4 citations
Decreased EEG sensitivity to alprazolam in subjects with a parental history of alcoholism
Ofra Sarid-Segal, Clifford M. Knapp, Ann Marie Ciraulo, David J. Greenblatt, Richard I. Shader, Domenic A. Ciraulo> ;Journal of Clinical Pharmacology. 2000 Jan 1
16 citations
Alterations in pharmacodynamics of anxiolytics in abstinent alcoholic men: subjective responses, abuse liability, and electroencephalographic effects of alprazolam, di...
Domenic A. Ciraulo, Jamie G. Barnhill, Ann Marie Ciraulo, Ofra Sarid-Segal, Clifford M. Knapp, David J. Greenblatt, Richard I. Shader> ;Journal of Clinical Pharmacology. 1997 Jan 1
15 citations
Liability to alprazolam abuse in daughters of alcoholics.
Domenic A. Ciraulo, Ofra Sarid-Segal, Clifford M. Knapp, Ann Marie Ciraulo, David J. Greenblatt, Richard I. Shader> ;The American Journal of Psychiatry. 1996 Jul 1
88 citations
A placebo-controlled trial of fluoxetine added to neuroleptic in patients with schizophrenia
Donald C. Goff, Kamal K. Midha, Ofra Sarid-Segal, John W. Hubbard, Edward Amico> ;Psychopharmacology. 1995 Feb 1
28 citations
A Placebo-Controlled Trial of Selegiline (L-Deprenyl) in the Treatment of Tardive Dyskinesia
Donald C. Goff, Perry F. Renshaw, Ofra Sarid-Segal, Daniel A. Dreyfuss, Edward Amico, Domenic A. Ciraulo> ;Biological Psychiatry. 1993 May 15
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Hospital Affiliations

Veterans Affairs Boston Healthcare System - Jamaica PlainJamaica Plain, Massachusetts
Mount Auburn HospitalCambridge, Massachusetts
Boston Medical CenterBoston, Massachusetts