OrenAbrahamLevyMD

PubMed

• 74 citations
  Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial.
  Tanya Simuni, Brian K. Fiske, Kalpana Merchant, Christopher S. Coffey, Elizabeth A. Klingner, Chelsea Caspell-Garcia, David-Erick Lafontant, Helen Matthews, Richard K....> ;JAMA Neurology. 2021 Mar 1
• 16 citations
  Volumetric MRI-Based Biomarkers in Huntington's Disease: An Evidentiary Review.
  Kirsi M. Kinnunen, Adam J. Schwarz, Emily C. Turner, Dorian Pustina, Emily C. Gantman, Mark F. Gordon, Richard Joules, Ariana P. Mullin, Rachael I. Scahill, Nellie Geo...> ;Frontiers in Neurology. 2021 Jan 1
• 19 citations
  Longitudinal measurements of glucocerebrosidase activity in Parkinson’s patients
  Roy N. Alcalay, Pavlina Wolf, Ming Sum Ruby Chiang, Karolina Helesicova, Xiaokui Kate Zhang, Kalpana Merchant, Samantha J. Hutten, Clemens R. Scherzer, Chelsea Caspell...> ;Annals of Clinical and Translational Neurology. 2020 Sep 5
• 12 citations
  Analysis of common and rare VPS13C variants in late-onset Parkinson disease.
  Uladzislau Rudakou, Jennifer A. Ruskey, Lynne Krohn, Sandra B. Laurent, Dan Spiegelman, Lior Greenbaum, Gilad Yahalom, Alex Desautels, Jacques Montplaisir, Stanley Fah...> ;Neurology. Genetics. 2020 Jan 9
• 54 citations
  Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase.
  Thibaut Imberdis, Joseph Negri, Nagendran Ramalingam, Elizabeth Terry-Kantor, Gary P.H. Ho, Saranna Fanning, Georgia L. Stirtz, Tae-Eun Kim, Oren A. Levy, Tracy L. You...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 8
• 10 citations
  Stress-induced phospho-ubiquitin formation causes parkin degradation
  Lyudmila Kovalchuke, Eugene V. Mosharov, Oren A. Levy, Lloyd A. Greene> ;Scientific Reports. 2019 Aug 12
• 65 citations
  SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease
  Roy N. Alcalay, Victoria Mallett, Benoît Vanderperre, Omid Tavassoly, Yves Dauvilliers, Richard Y.J. Wu, Jennifer A. Ruskey, Claire S. Leblond, Amirthagowri Ambalavana...> ;Movement Disorders. 2019 Apr 1
• 40 citations
  Increased yield of full GBA sequencing in Ashkenazi Jews with Parkinson's disease.
  Jennifer A. Ruskey, Lior Greenbaum, Léanne Roncière, Armaghan Alam, Dan Spiegelman, Christopher Liong, Oren A. Levy, Cheryl Waters, Stanley Fahn, Karen Marder, Wendy K...> ;European Journal of Medical Genetics. 2019 Jan 1
• 2 citations
  Association of Low Lysosomal Enzymes Activity With Brain Arterial Dilatation.
  Harsh Shah, Christopher Liong, Oren A. Levy, Cheryl Waters, Stanley Fahn, Karen Marder, Un Jung Kang, Pavlina Wolf, Petra Oliva, Kate Zhang, Roy N. Alcalay, Jose Gutie...> ;Stroke. 2018 Aug 1
• 6 citations
  Context-dependent expression of a conditionally-inducible form of active Akt
  Soyeon Park, Robert E. Burke, Tatyana Kareva, Nikolai Kholodilov, Pascaline Aimé, Thomas F. Franke, Oren A. Levy, Lloyd A. Greene> ;Plos One. 2018 Jun 19
• 24 citations
  Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease.
  Xiaotian Sun, Pascaline Aimé, David Dai, Nagendran Ramalingam, John F. Crary, Robert E. Burke, Lloyd A. Greene, Oren A. Levy> ;Experimental Neurology. 2018 Feb 9
• 50 citations
  Alpha galactosidase A activity in Parkinson's disease.
  Roy N. Alcalay, Pavlina Wolf, Oren A. Levy, Un Jung Kang, Cheryl Waters, Stanley Fahn, Blair Ford, Sheng-Han Kuo, Nora Vanegas, H. Shah, Christopher Liong, S. Narayan,...> ;Neurobiology of Disease. 2018 Feb 2
• 4 citations
  Spasmodic Dysphonia in Hereditary Spastic Paraplegia Type 7
  Devin Hall, Nicholas Stong, Natalie Lippa, Michael J. Pitman, Seth L. Pullman, Oren A. Levy> ;Movement Disorders Clinical Practice. 2018 Mar 1
• 64 citations
  Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells.
  Ulf Dettmer, Nagendran Ramalingam, Victoria E. von Saucken, Tae-Eun Kim, Andrew J. Newman, Elizabeth Terry-Kantor, Silke Nuber, Maria Ericsson, Saranna Fanning, Tim Ba...> ;Human Molecular Genetics. 2017 Sep 15
• 76 citations
  Elevated GM3 plasma concentration in idiopathic Parkinson’s disease: A lipidomic analysis
  Robin B. Chan, Adler J. Perotte, Bowen Zhou, Christopher Liong, Evan Shorr, Karen Marder, Un Jung Kang, Cheryl Waters, Oren A. Levy, Yimeng Xu, Hong Bin Shim, Itsik Pe...> ;Plos One. 2017 Feb 17
• 12 citations
  The effect of MAPT haplotype on neocortical Lewy body pathology in Parkinson disease.
  Daphne Robakis, Etty Cortes, Lorraine N. Clark, Jean Paul G. Vonsattel, Tuhin Virmani, Roy N. Alcalay, John F. Crary, Oren A. Levy> ;Journal of Neural Transmission. 2016 Apr 20
• 30 citations
  SCARB2 variants and glucocerebrosidase activity in Parkinson’s disease
  Roy N. Alcalay, Oren A. Levy, Pavlina Wolf, Petra Oliva, Xiaokui Kate Zhang, Cheryl Waters, Stanley Fahn, Un Jung Kang, Christopher Liong, Blair Ford, Pietro Mazzoni, ...> ;NPJ Parkinson's Disease. 2016 Mar 10
• 272 citations
  Glucocerebrosidase activity in Parkinson’s disease with and without GBA mutations
  Roy N. Alcalay, Oren A. Levy, Cheryl Waters, Stanley Fahn, Blair Ford, Sheng-Han Kuo, Pietro Mazzoni, Michael W. Pauciulo, William C. Nichols, Ziv Gan-Or, Guy A. Roule...> ;Brain. 2015 Sep 1
• 38 citations
  Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models
  Pascaline Aimé, Xiaotian Sun, Neela Zareen, Apeksha Rao, Zachary Berman, Laura A. Volpicelli-Daley, Paulette Bernd, John F. Crary, Oren A. Levy, Lloyd A. Greene> ;The Journal of Neuroscience. 2015 Jul 29
• 17 citations
  Genetic markers of Restless Legs Syndrome in Parkinson disease.
  Ziv Gan-Or, Roy N. Alcalay, Anat Bar-Shira, Claire S. Leblond, Ronald B. Postuma, Shay Ben-Shachar, Cheryl Waters, Amelie Johnson, Oren A. Levy, Anat Mirelman, Mali Ga...> ;Parkinsonism & Related Disorders. 2015 Jun 1
• 32 citations
  Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease
  Joan Romaní-Aumedes, Mercè Canal, Núria Martín-Flores, Xiaotian Sun, V Pérez-Fernández, S Wewering, Rubén Fernández-Santiago, Mario Ezquerra, Claustre Pont-Sunyer, A L...> ;Cell Death & Disease. 2014 Aug 7
• 151 citations
  Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes.
  Roy N. Alcalay, Tama Dinur, Timothy Quinn, Karina Sakanaka, Oren A. Levy, Cheryl Waters, Stanley Fahn, Tsvyatko Dorovski, Wendy K. Chung, Michael W. Pauciulo, William ...> ;JAMA Neurology. 2014 Jun 1
• 118 citations
  Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.
  Roy N. Alcalay, Anat Mirelman, Rachel Saunders-Pullman, Ming X. Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe-Reilly, Tanya Gurevich, Anat Bar S...> ;Movement Disorders. 2013 Dec 1
• 25 citations
  Knowledge of and interest in genetic results among Parkinson disease patients and caregivers.
  Karina Sakanaka, Cheryl Waters, Oren A. Levy, Elan D. Louis, Wendy K. Chung, Karen Marder, Roy N. Alcalay> ;Journal of Genetic Counseling. 2014 Feb 1
• 43 citations
  Postural and Intention Tremors: A Detailed Clinical Study of Essential Tremor vs. Parkinson’s Disease
  Eliezer J Sternberg, Roy N. Alcalay, Oren A. Levy, Elan D. Louis> ;Frontiers in Neurology. 2013 May 10
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