OrsolyaZsuzsannaPolgarMDPhD

PubMed

• 32 citations
  Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2
  Orsolya Polgar, Caterina Ieranò, Akina Tamaki, Bradford J. Stanley, Yvona Ward, Di Xia, Nadya I. Tarasova, Robert W. Robey, Susan E. Bates> ;Biochemistry. 2010 Mar 16
• 22 citations
  Arginine 383 is a crucial residue in ABCG2 biogenesis.
  Orsolya Polgar, Lilangi S. Ediriwickrema, Robert W. Robey, Ajay Sharma, Ramanujan S. Hegde, Yongfu Li, Di Xia, Yvona Ward, Michael Dean, Csilla Özvegy-Laczka, Balázs S...> ;Biochimica Et Biophysica Acta. 2009 Jul 1
• 3 citations
  The 315-316 deletion determines the BXP-21 antibody epitope but has no effect on the function of wild type ABCG2 or the Q141K variant.
  Orsolya Polgar, John F. Deeken, Lilangi S. Ediriwickrema, Akina Tamaki, Seth M. Steinberg, Robert W. Robey, Susan E. Bates> ;Molecular and Cellular Biochemistry. 2009 Feb 1
• 338 citations
  ABCG2: a perspective.
  Robert W. Robey, Kenneth K.K. To, Orsolya Polgar, Marius Dohse, Patricia Fetsch, Michael Dean, Susan E. Bates> ;Advanced Drug Delivery Reviews. 2009 Jan 31
• 20 citations
  Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.
  Robert W. Robey, Tomasz Obrzut, Suneet Shukla, Orsolya Polgar, Sira Macalou, Julian C. Bahr, Attilio Di Pietro, Suresh V. Ambudkar, Susan E. Bates> ;Cancer Chemotherapy and Pharmacology. 2009 Jan 9
• 30 citations
  Reduced Expression of DNA Topoisomerase I in SF295 Human Glioblastoma Cells Selected for Resistance to Homocamptothecin and Diflomotecan
  Zhi-Yong Liao, Robert W. Robey, Josée Guirouilh-Barbat, Kenneth K.W. To, Orsolya Polgar, Susan E. Bates, Yves Pommier> ;Molecular Pharmacology. 2008 Feb 1
• 98 citations
  Histone Modifications at the ABCG2 Promoter following Treatment with Histone Deacetylase Inhibitor Mirror Those in Multidrug-Resistant Cells
  Kenneth K.W. To, Orsolya Polgar, Lyn Mickley Huff, Kuniaki Morisaki, Susan E. Bates> ;Molecular Cancer Research. 2008 Jan 1
• 154 citations
  ABCG2: structure, function and role in drug response
  Orsolya Polgar, Robert W. Robey, Susan E. Bates> ;Expert Opinion on Drug Metabolism & Toxicology. 2008 Jan 1
• 34 citations
  Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study.
  Yong-Fu Li, Orsolya Polgar, Masaki Okada, Lothar Esser, Susan E. Bates, Di Xia> ;Journal of Molecular Graphics & Modelling. 2007 Mar 1
• 295 citations
  ABCG2: determining its relevance in clinical drug resistance.
  Robert W. Robey, Orsolya Polgar, John Deeken, Kin Wah To, Susan E. Bates> ;Cancer Metastasis Reviews. 2007 Feb 24
• 17 citations
  The livestock photosensitizer, phytoporphyrin (phylloerythrin), is a substrate of the ATP-binding cassette transporter ABCG2.
  Robert W. Robey, Patricia Fetsch, Orsolya Polgar, Michael Dean, Susan E. Bates> ;Research in Veterinary Science. 2006 Dec 1
• 26 citations
  Mutational Studies of G553 in TM5 of ABCG2: a Residue Potentially Involved in Dimerization
  Orsolya Polgar, Csilla Özvegy-Laczka, Robert W. Robey, Kuniaki Morisaki, Masaki Okada, Akina Tamaki, Gabriella Köblös, N. Barry Elkind, Yvona Ward, Michael Dean, Baláz...> ;Biochemistry. 2006 Apr 25
• 173 citations
  Single nucleotide polymorphisms modify the transporter activity of ABCG2
  Kuniaki Morisaki, Robert W. Robey, Csilla Özvegy-Laczka, Yasumasa Honjo, Orsolya Polgar, Kenneth Steadman, Balázs Sarkadi, Susan E. Bates> ;Cancer Chemotherapy and Pharmacology. 2005 Apr 19
• 150 citations
  ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy.
  Robert W. Robey, Kenneth Steadman, Orsolya Polgar, Susan E. Bates> ;Cancer Biology & Therapy. 2005 Feb 1
• 84 citations
  Mutational Analysis of ABCG2: Role of the GXXXG Motif
  Orsolya Polgar, Robert W. Robey, Kuniaki Morisaki, Michael Dean, Christopher J. Michejda, Zuben E. Sauna, Suresh V. Ambudkar, Nadya I. Tarasova, Susan E. Bates> ;Biochemistry. 2004 Jul 2
• 275 citations
  Pheophorbide a is a specific probe for ABCG2 function and inhibition.
  Robert W. Robey, Kenneth Steadman, Orsolya Polgar, Kuniaki Morisaki, Margaret Blayney, Prakash Mistry, Susan E. Bates> ;Cancer Research. 2004 Feb 15
• 84 citations
  ABC transporters and inhibitors: new targets, new agents.
  Gregory D. Leonard, Orsolya Polgar, Susan E. Bates> ;Current Opinion in Investigational Drugs. 2002 Nov 1
• Join now to see all