
Page B Pennell MD MSci (hon) (She/Her)
Epilepsy, Neurophysiology
Chair, Department of Neurology, UPMC Henry B. Higman Professor of Neurology
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8th floor, Kaufmann Medical Building3471 5th AvenuePittsburgh, PA 15213
Phone+1 412-692-4622
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Summary
- Dr. Page B. Pennell is the Chair of Neurology and Henry B. Higman Professor at the University of Pittsburgh School of Medicine and UPMC.
She completed her medical education at the University of Florida College of Medicine and her neurology residency and epilepsy fellowship at the University of Michigan. Her former roles include Professor of Harvard Medical School and Vice-Chair of Academic Affairs in the department of neurology at Brigham and Women's Hospital, and Associate Professor and Program Director of Epilepsy at Emory University. Dr. Pennell's primary areas of research include pharmacokinetics of anti-seizure medications (ASMs) during different reproductive phases and sex-specific issues for women with epilepsy: pregnancy planning, epilepsy management during pregnancy with an emphasis on optimizing maternal and fetal outcomes, and the effects of neuroactive steroids on seizure provocation. She has been PI on several NIH-funded studies including the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study. She has published widely on these topics. Dr. Pennell has also been recognized in several top doctor listings by Castle Connolly.
Education & Training
University of MichiganResidency, Neurology, 1990 - 1993
University of FloridaInternship, Internal Medicine, 1989 - 1990
University of Florida College of MedicineClass of 1989
Certifications & Licensure
PA State Medical License 2021 - 2026
MA State Medical License 2009 - 2022
GA State Medical License 1995 - 2011
MI State Medical License 1993 - 1997
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2017
- CMS Meaningful Use Stage 1 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2017
- CMS Meaningful Use Stage 2 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2017
Clinical Trials
Publications & Presentations
PubMed
- Contraceptive and Enzyme-Inducing Antiseizure Medication Coprescription Among US Medicaid Beneficiaries With Epilepsy.Elizabeth Harrison, Laura Kirkpatrick, Caryn Dutton, Wesley T Kerr, Scott Rothenberger
Neurology. 2026-11-10 - Association Between Alzheimer Pathology, Sleep, and Cognition in Patients With Late-Onset Unexplained Epilepsy.Rani A Sarkis, Hyun-Sik Yang, Lei Liu, Alice D Lam, Milena Pavlova
Neurology. 2026-09-22 - Breastfeeding and Neurodevelopmental Outcomes in Children of Women Taking Antiseizure Medications.Yi Li, David W Loring, Morris J Cohen, Elizabeth E Gerard, Angela K Birnbaum
JAMA Network Open. 2026-09-01
Journal Articles
- Changes in Seizure Frequency and Antiepileptic Therapy During PregnancyPage B Pennell, Jacqueline A French, Laura Kalayjian, Patricia Penovich, Evan Gedzelman, Alison M Pack, Kimford J Meador, The New England Journal of Medicine
- Exposure of Infants Who Are Breastfed to Antiepileptic Drugs—ReplyKimford J Meador, Page B Pennell, JAMA Neurology
Authored Content
- Exposure of Infants Who Are Breastfed to Antiepileptic Drugs—ReplyAugust 2020
Press Mentions
Newer Epilepsy Medications Used During Pregnancy Do Not Affect Neurological Development in ChildrenNovember 27th, 2024
Anti-Epileptic Dosages Associated with Breakthrough Seizures in Pregnancy – MONEAD StudyFebruary 22nd, 2022
Blood Levels of Common Antiepileptic Drugs Drop During Pregnancy, Causing Breakthrough SeizuresFebruary 14th, 2022
Grant Support
- N3-PREP (Neurology, Neurosurgery, & Neuropathology Pitt Research Education Program)UNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- Physiological-based Pharmacokinetics Approach to Determine the Extent of Drug Exposure of Antiseizure Medications During Pregnancy and BreastfeedingUNIVERSITY OF MINNESOTA2021–2027
- Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)NINDS and NICHD, NIH2012–2017
- Neuroactive Steroids And Seizure Control During Pregnancy In Women With EpilepsyNational Institute Of Neurological Disorders And Stroke2009–2010
- Metabolism Of Antiepileptic DrugsNational Center For Research Resources2006
Committees
- President, American Epilepsy Society 2018 - 2019
Professional Memberships
- Member
- Member
- American Neurological AssociationMember
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