PanZhengMDPhD

PubMed

• 2 citations
  A phase 2 trial of CD24Fc for prevention of graft-versus-host disease.
  John Magenau, Samantha Jaglowski, Joseph Uberti, Sherif S Farag, Mary Mansour Riwes, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Thomas Braun, Ma...> ;Blood. 2024 Jan 4
• 1 citations
  Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease.
  Christopher Bailey, Yuanyi Wei, Jinsong Yan, Dan Huang, Peng Zhang, Chong Qi, Christopher Lazarski, JuanJuan Su, Fei Tang, Chun-Shu Wong, Pan Zheng, Yan Liu, Yang Liu,...> ;Cell Reports. Medicine. 2023 Nov 21
• 2 citations
  A novel aptamer-based small RNA delivery platform and its application to cancer therapy.
  Toshihiko Tanno, Peng Zhang, Christopher Bailey, Yin Wang, Wannaporn Ittiprasert, Martin Devenport, Pan Zheng, Yang Liu> ;Genes & Diseases. 2023 May 1
• 7 citations
  CD24-Siglec interactions in inflammatory diseases.
  Yang Liu, Pan Zheng> ;Frontiers in Immunology. 2023 Jan 1
• 1 citations
  CD24-Fc suppression of immune related adverse events in a therapeutic cancer vaccine model of murine neuroblastoma.
  Xiaofang Wu, Priya Srinivasan, Mousumi Basu, Talia Zimmerman, Samuel Li, Yin Wang, Pan Zheng, Yang Liu, Anthony David Sandler> ;Frontiers in Immunology. 2023 Jan 1
• 18 citations
  CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
  Xu Wang, Mingyue Liu, Jifeng Zhang, Nicholas K Brown, Peng Zhang, Yan Zhang, Heng Liu, Xuexiang Du, Wei Wu, Martin Devenport, Weng Tao, Yang Mao-Draayer, Guo-Yun Chen,...> ;Cell Metabolism. 2022 Aug 2
• 25 citations
  Efficacy and safety of CD24Fc in hospitalised patients with COVID-19: a randomised, double-blind, placebo-controlled, phase 3 study.
  James Welker, Juan D Pulido, Andrew T Catanzaro, Carlos D Malvestutto, Zihai Li, Jonathan B Cohen, Eric D Whitman, Dana Byrne, Olivia K Giddings, Jordan E Lake, Joel V...> ;The Lancet. Infectious Diseases. 2022 May 1
• 8 citations
  Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology.
  No-Joon Song, Carter Allen, Anna E Vilgelm, Brian P Riesenberg, Kevin P Weller, Kelsi Reynolds, Karthik B Chakravarthy, Amrendra Kumar, Aastha Khatiwada, Zequn Sun, An...> ;Journal of Hematology & Oncology. 2022 Jan 10
• 5 citations
  Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes.
  Jun-yi Zhu, Xiaohu Huang, Yulong Fu, Yin Wang, Pan Zheng, Yang Liu, Zhe Han> ;Disease Models & Mechanisms. 2022 Feb 1
• 20 citations
  The HIF1α-PDGFD-PDGFRα axis controls glioblastoma growth at normoxia/mild-hypoxia and confers sensitivity to targeted therapy by echinomycin.
  Gong Peng, Yin Wang, Pengfei Ge, Christopher Bailey, Peng Zhang, Di Zhang, Zhaoli Meng, Chong Qi, Qian Chen, Jingtao Chen, Junqi Niu, Pan Zheng, Yang Liu, Yan Liu> ;Journal of Experimental & Clinical Cancer Research. 2021 Sep 1
• 33 citations
  Immunological Insights Into the Therapeutic Roles of CD24Fc Against Severe COVID-19
  No-Joon Song, Carter Allen, Anna E. Vilgelm, Brian Riesenberg, Kevin P. Weller, Kelsi Reynolds, Karthik Chakravarthy, Amrendra Kumar, Aastha Khatiwada, Zequn Sun, Anju...> ;Medrxiv. 2021 Aug 23
• 7 citations
  Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor.
  Yan Liu, Marie V. Nelson, Christopher Bailey, Peng Zhang, Pan Zheng, Jeffrey S. Dome, Yang Liu, Yin Wang> ;Oncogene. 2021 Jun 21
• 31 citations
  MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination.
  Xiaofang Wu, Marie V. Nelson, Mousumi Basu, Priya Srinivasan, Christopher A. Lazarski, Peng Zhang, Pan Zheng, Anthony D. Sandler> ;Journal for Immunotherapy of Cancer. 2021 Mar 1
• 6 citations
  Dual Targeting Oncoproteins MYC and HIF1α Regresses Tumor Growth of Lung Cancer and Lymphoma.
  Xiaohu Huang, Yan Liu, Yin Wang, Christopher Bailey, Pan Zheng, Yang Liu> ;Cancers. 2021 Feb 9
• 5 citations
  Structure of CTLA-4 complexed with a pH-sensitive cancer immunotherapeutic antibody.
  Han Gao, Haiyan Cai, Jia Liu, Xiaoxiao Wang, Pan Zheng, Martin Devenport, Ting Xu, Fei Dou, Yang Liu, Aiwu Zhou> ;Cell Discovery. 2020 Nov 3
• 21 citations
  Microsatellite instability status differentially associates with intratumoral immune microenvironment in human cancers.
  Peng Zhang, Mingyue Liu, Ya Cui, Pan Zheng, Yang Liu> ;Briefings in Bioinformatics. 2021 May 20
• 31 citations
  Liposomal formulation of HIF-1α inhibitor echinomycin eliminates established metastases of triple-negative breast cancer
  Christopher Bailey, Yan Liu, Gong Peng, Huixia Zhang, Miao He, Duxin Sun, Pan Zheng, Yang Liu, Yin Wang> ;Nanomedicine. 2020 Jul 30
• 27 citations
  CD24Fc protects against viral pneumonia in simian immunodeficiency virus-infected Chinese rhesus monkeys.
  Ren-Rong Tian, Ming-Xu Zhang, Mingyue Liu, Xianfeng Fang, Dongling Li, Liguo Zhang, Pan Zheng, Yong-Tang Zheng, Yang Liu> ;Cellular & Molecular Immunology. 2020 May 7
• 19 citations
  Therapeutic targeting of TP53-mutated acute myeloid leukemia by inhibiting HIF-1α with echinomycin.
  Yin Wang, Yan Liu, Christopher Bailey, Huixia Zhang, Miao He, Duxin Sun, Peng Zhang, Brian Parkin, Maria R. Baer, Pan Zheng, Sami N. Malek, Yang Liu> ;Oncogene. 2020 Feb 15
• 11 citations
  Mechanism- and Immune Landscape-Based Ranking of Therapeutic Responsiveness of 22 Major Human Cancers to Next Generation Anti-CTLA-4 Antibodies
  Peng Zhang, Xinxin Xiong, Christian Rolfo, Xuexiang Du, Yan Zhang, Han Yang, Alessandro Russo, Martin Devenport, Penghui Zhou, Yang Liu, Pan Zheng> ;Cancers. 2020 Jan 24
• 76 citations
  Preserving the CTLA-4 Checkpoint for Safer and More Effective Cancer Immunotherapy
  Yang Liu, Pan Zheng> ;Trends in Pharmacological Sciences. 2020 Jan 1
• 130 citations
  T Regulatory Cells and Priming the Suppressive Tumor Microenvironment.
  Christina Paluskievicz, Xuefang Cao, Reza Abdi, Pan Zheng, Yang Liu, Jonathan S. Bromberg> ;Frontiers in Immunology. 2019 Oct 15
• 1 citations
  En masse discovery of anti-cancer human monoclonal antibodies by de novo assembly of immunoglobulin sequences from transcriptomes and genome sequences of cancer tissues.
  Peng Zhang, Hung-Yen Chou, Lei Young, Pan Zheng, Yang Liu> ;Cellular & Molecular Immunology. 2019 Sep 27
• 64 citations
  Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.
  Yan Zhang, Xuexiang Du, Mingyue Liu, Fei Tang, Peng Zhang, Chunxia Ai, James K. Fields, Eric J. Sundberg, Olga Latinovic, Martin Devenport, Pan Zheng, Yang Liu> ;Cell Research. 2019 Jul 2
• 15 citations
  Amplification of the CD24 Gene Is an Independent Predictor for Poor Prognosis of Breast Cancer.
  Peng Zhang, Pan Zheng, Yang Liu> ;Frontiers in Genetics. 2019 Jun 12
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Journal Articles

• CD24 and Fc Fusion Protein Protects SIVmac239-Infected Chinese Rhesus Macaque Against Progression to AIDS  
  Pan Zheng, MD, ScienceDirect