PatriciaDHinkleMD

PubMed

• Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane.
  Malik, S.,Dolan, T. M.,Maben, Z. J.,Hinkle, P. M.> ;J. Biol. Chem.. 2015 Oct 02
• Ostα-/- mice are not protected from western diet-induced weight gain.
  Hammond, C. L.,Wheeler, S. G.,Ballatori, N.,Hinkle, P. M.> ;Physiol Rep. 2015 Jan 30
• 14 citations
  Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity
  Sadie G. Wheeler, Christine L. Hammond, François R Jornayvaz, Varman T. Samuel, Gerald I. Shulman, Carol J. Soroka, James L. Boyer, Patricia M. Hinkle, Nazzareno Balla...> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2014 Mar 1
• Developmental Control of the Melanocortin-4 Receptor by MRAP2 Proteins in Zebrafish
  Patricia Hinkle, MD> ;Science Magazine. 2013 Jul 19
• siRNA Screen Identifies the Phosphatase Acting on the G Protein-Coupled Thyrotropin-Releasing Hormone Receptor.
  Gehret, A. U.,Hinkle, P. M.> ;ACS Chem. Biol.. 2013 Mar 15
• Detection of G protein-coupled receptors by immunofluorescence microscopy.
  Hinkle, P. M., Puskas, J. A.> ;Methods Mol Biol. 2004
• Ca(2+)-induced Ca(2+) release in the pancreatic beta-cell: direct evidence of endoplasmic reticulum Ca(2+) release.
  Graves, T. K., Hinkle, P. M.> ;Endocrinology. 2003 Aug
• Thyrotropin-releasing hormone receptor processing: role of ubiquitination and proteasomal degradation.
  Cook, L. B., Zhu, C. C., Hinkle, P. M.> ;Mol Endocrinol. 2003 Sep
• Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides.
  Goubaeva, F., Ghosh, M., Malik, S., Yang, J., Hinkle, P. M., Griendling, K. K., Neubig, R. R., Smrcka, A. V.> ;J Biol Chem. 2003 May 30
• Endoplasmic reticulum calcium storage and release in cells expressing misfolded growth hormone.
  Graves, T. K., Hinkle, P. M.> ;Growth Horm IGF Res. 2003 Feb
• Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides.
  Hinkle, P. M., Pekary, A. E., Senanayaki, S., Sattin, A.> ;Brain Res. 2002 May 10
• Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation.
  Zhu, C. C., Cook, L. B., Hinkle, P. M.> ;J Biol Chem. 2002 Aug 2
• Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers.
  Sebag, J. A., Hinkle, P. M.> ;Proc Natl Acad Sci U S A. 2007 Dec 18
• A novel TRH analog, Glp-Asn-Pro-D-Tyr-D-TrpNH2, binds to [3H][3-Me-His2]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expres...
  Hogan, N., O'Boyle, K. M., Hinkle, P. M., Kelly, J. A.> ;Neurosci Lett. 2008 Jan 24
• Dimerization of the thyrotropin-releasing hormone receptor potentiates hormone-dependent receptor phosphorylation.
  Song, G. J., Jones, B. W., Hinkle, P. M.> ;Proc Natl Acad Sci U S A. 2007 Nov 13
• Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone.
  Scalabrino, G. A., Hogan, N., O'Boyle, K. M., Slator, G. R., Gregg, D. J., Fitchett, C. M., Draper, S. M., Bennett, G. W., Hinkle, P. M., Bauer, K., Williams, C. H., T...> ;Neuropharmacology. 2007 Jun
• Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies.
  Jones, B. W., Song, G. J., Greuber, E. K., Hinkle, P. M.> ;J Biol Chem. 2007 Apr 27
• Regulation of endogenous melanocortin-4 receptor expression and signaling by glucocorticoids.
  Sebag, J. A., Hinkle, P. M.> ;Endocrinology. 2006 Dec
• Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor.
  Jones, B. W., Hinkle, P. M.> ;J Biol Chem. 2005 Nov 18
• Regulated dimerization of the thyrotropin-releasing hormone receptor affects receptor trafficking but not signaling.
  Song, G. J., Hinkle, P. M.> ;Mol Endocrinol. 2005 Nov
• Fate of internalized thyrotropin-releasing hormone receptors monitored with a timer fusion protein.
  Cook, L. B., Hinkle, P. M.> ;Endocrinology. 2004 Jul
• Agonist-dependent up-regulation of thyrotrophin-releasing hormone receptor protein.
  Cook, L. B., Hinkle, P. M.> ;Biochem J. 2004 Jun 15
• Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s.
  Liang, L., Sebag, J. A., Eagelston, L., Serasinghe, M. N., Veo, K., Reinick, C., Angleson, J., Hinkle, P. M., Dores, R. M.> ;Gen Comp Endocrinol. 2011 Oct 1
• Use of chimeric melanocortin-2 and -4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein.
  Hinkle, P. M., Serasinghe, M. N., Jakabowski, A., Sebag, J. A., Wilson, K. R., Haskell-Luevano, C.> ;Eur J Pharmacol. 2011 Jun 11
• Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2.
  Sebag, J. A., Hinkle, P. M.> ;Sci Signal. 2010
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