Patricia Leonor Musolino MD PhD
Co-Director Pediatric Stroke and Cerebrovascular Service, Massachusetts General Hospital
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185 Cambridge StSuite 5248Boston, MA 02114
Phone+1 617-643-9644
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Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Child Neurology, 2008 - 2011
Nicklaus Children's HospitalResidency, Pediatrics, 2006 - 2008
University of Buenos AiresClass of 2003
Certifications & Licensure
MA State Medical License 2009 - 2026
ME State Medical License 2013 - 2022
NY State Medical License 2020 - 2022
NH State Medical License 2013 - 2021
OK State Medical License 2017 - 2021
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology
UCNSNeurocritical Care
Clinical Trials
- Immersive Virtual Reality for Visuo-motor Integration Skill Assessment Start of enrollment: 2021 May 01
- Mucolipidosis Type IV Natural History Study Start of enrollment: 2023 Mar 15
Roles: Contact, Principal Investigator
Publications & Presentations
PubMed
- Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice.Christiano R R Alves, Sabyasachi Das, Vijai Krishnan, Leillani L Ha, Lauren R Fox
Nature Biomedical Engineering. 2025-09-11 - COL4A1 and COL4A2-related disorders: Clinical features, diagnostic guidelines, and management.Diana Tambala, Rachel Vassar, John Snow, Simona Balestrini, Anna Bersano
Genetics in Medicine. 2025-09-01 - Ophthalmic Artery Occlusion as a Novel Ophthalmic Manifestation of ACTA2- Related Vascular Smooth Muscle Disorder.Srujay Pandiri, Celine Chaaya, Ryan S Meshkin, Sandra Hoyek, Joseph F Rizzo 3rd
Ophthalmic Surgery, Lasers & Imaging Retina. 2025-09-01
Press Mentions
Tailored Gene-Editing Technology Emerges as a Promising Treatment for Fatal Pediatric DiseasesSeptember 11th, 2025
Customized Gene-Editing Technology Shows Potential to Treat Lethal Pediatric DiseaseSeptember 11th, 2025- A Mass General Team Is the First to Trace a Rare Smooth Muscle Disorder to a Single Mutation in a Non-Coding GeneMarch 1st, 2023
Grant Support
- Modeling and Therapeutic Approaches for Genetic VasculopathiesMASSACHUSETTS GENERAL HOSPITAL2022–2027
- Modeling and Therapeutic Approaches for Genetic VasculopathiesMASSACHUSETTS GENERAL HOSPITAL2022–2027
- Gene therapy for disorders of the extracellular matrixUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2023–2026
- Effects of ABCD1 Deficiency on Endothelial Function and Permeability to Leukocytes in Cerebral X-linked AdrenoleukodystrophyMASSACHUSETTS GENERAL HOSPITAL2020–2025
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