Paul Martin Busse MD PhD

Clinical Director, Department of Radiation Oncology, Massachusetts General Hospital

100 Blossom StCox LLBoston, MA 02114
Phone+1 617-724-1548
Fax+1 617-724-8334

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Education & Training

Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Radiation Oncology, 1983 - 1986
Washington University/B-JH/SLCH ConsortiumInternship, Internal Medicine, 1982 - 1983
Saint Louis University School of MedicineClass of 1982

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Certifications & Licensure

MA State Medical License 1986 - 2027
NH State Medical License 2007 - 2025
WV State Medical License 1985 - 1987
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification Partners Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016-2017
CMS Meaningful Use Stage 2 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016-2017
CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2014, 2016-2017

Clinical Trials

Boron Neutron Capture Therapy in Treating Patients With Stage III Melanoma
UNKNOWN
PHASE1
Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain
COMPLETED
PHASE1, PHASE2
Boron Neutron Capture Therapy in Treating Patients With Melanoma
COMPLETED
PHASE2

Publications & Presentations

PubMed

Proton versus photon therapy for oropharyngeal cancer - Authors' reply.
Steven J Frank, Paul M Busse, J Jack Lee, Robert L Foote,
Lancet. 2026-05-16
15 citations
Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA: a multicentre, randomised, open-label, non-inferiority phase 3 trial.
Steven J Frank, Paul M Busse, J Jack Lee, David I Rosenthal, Mike Hernandez
Lancet. 2026-01-10
95 citations
NCCN Guidelines® Insights: Head and Neck Cancers, Version 2.2025.
A Dimitrios Colevas, Anthony J Cmelak, David G Pfister, Sharon Spencer, Douglas Adkins
Journal of the National Comprehensive Cancer Network. 2025-02-01

Journal Articles

Comparing Intensity-Modulated Proton Therapy with Intensity-Modulated Photon Therapy for Oropharyngeal Cancer: The Journey from Clinical Trial Concept to Activation
Steven J Frank, G Brandon Gunn, Adam S Garden, Katherine Hutcheson, Paul M Busse, Merrill S Kies, Nancy Y Lee, Alexander Lin, Erich M Sturgis, C David Fuller, J Jack L..., ScienceDirect

Grant Support

A Phase II Trial For Neutron Capture Therapy In MelanomaNational Cancer Institute2002–2003
Phase I / II Trial For Neutron Capture TherapyNational Cancer Institute2001