PaulJanDeutschMD

PubMed

• 25 citations
  Safety and Pharmacokinetics of Higher Doses of Caspofungin in Healthy Adult Participants
  Elizabeth Migoya, Goutam C. Mistry, Julie A. Stone, Wendy Comisar, Peng Sun, Alisha Norcross, Sheng Bi, Gregory A. Winchell, Kalyan Ghosh, Naoto Uemera, Paul J. Deutsc...> ;Journal of Clinical Pharmacology. 2011 Feb 1
• 46 citations
  Single- and Multiple-Dose Administration of Caspofungin in Patients With Hepatic Insufficiency: Implications for Safety and Dosing Recommendations
  Goutam C. Mistry, Elizabeth Migoya, Paul J. Deutsch, Gregory A. Winchell, Michael Hesney, Susan X. Li, Sheng Bi, Stacy C. Dilzer, Kenneth C. Lasseter, Julie A. Stone> ;Journal of Clinical Pharmacology. 2007 Aug 1
• Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women.
  Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen B, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE> ;Antimicrob. Agents Chemother.. 2007-02-01
• 29 citations
  The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers.
  A. Van Hecken, Marleen Depré, I De Lepeleire, C. Thach, M. Oeyen, J. Van Effen, T Laethem, Kathryn E. Mazina, Tami Crumley, Larissa Wenning, Keith Gottesdiener, Paul J...> ;European Journal of Clinical Pharmacology. 2007 Jan 3
• Pharmacokinetics of ertapenem in patients with varying degrees of renal insufficiency and in patients on hemodialysis.
  Mistry, G.C., Majumdar, A.K., Swan, S., Sica, D., Fisher, A., Xu, Y., Hesney, M., Xi, L., Wagner, J.A., Deutsch, P.J.> ;J Clin Pharmacol. 2006 Oct
• 91 citations
  Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.
  Jason S. Simon, Maha Karnoub, David J. Devlin, Maria G. Arreaza, Ping Qiu, Stephanie A. Monks, Michael E. Severino, Deutsch Paul J, Joanne Palmisano, Alan B. Sachs, Ma...> ;Genomics. 2005 Dec 1
• Single-dose pharmacokinetics and tolerability of alendronate 35- and 70-milligram tablets in children and adolescents with osteogenesis imperfecta type I.
  Ward LM, Denker AE, Porras A, Shugarts S, Kline W, Travers R, Mao C, Rauch F, Maes A, Larson P, Deutsch P, Glorieux FH> ;J. Clin. Endocrinol. Metab.. 2005-07-01
• 202 citations
  A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients.
  Hongyue Dai, Laura J. van't Veer, John Lamb, Yudong D. He, Mao Mao, Bernard M. Fine, René Bernards, Marc J. van de Vijver, Deutsch Paul J, Alan B. Sachs, Roland Stough...> ;Cancer Research. 2005 May 15
• Potential for interactions between caspofungin and nelfinavir or rifampin.
  Stone, J.A., Migoya, E.M., Hickey, L., Winchell, G.A., Deutsch, P.J., Ghosh, K., Freeman, A., Bi, S., Desai, R., Dilzer, S.C., Lasseter, K.C., Kraft, W.K., Greenberg, ...> ;Antimicrob Agents Chemother. 2004 Nov
• 63 citations
  A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer.
  Neil E. Martin, Thomas Brunner, Krystina D. Kiel, Thomas F. DeLaney, William F. Regine, Mohammed Mohiuddin, Ernest F. Rosato, Daniel G. Haller, James P. Stevenson, Deb...> ;Clinical Cancer Research. 2004 Aug 15
• 30 citations
  Pharmacokinetics of montelukast in asthmatic patients 6 to 24 months old.
  Elizabeth Migoya, Gregory L. Kearns, Alan Hartford, Jamie Zhao, Janet van Adelsberg, Carol A. Tozzi, Barbara Knorr, Paul J. Deutsch> ;Journal of Clinical Pharmacology. 2004 May 1
• Indinavir and rifabutin drug interactions in healthy volunteers.
  Kraft, W.K., McCrea, J.B., Winchell, G.A., Carides, A., Lowry, R., Woolf, E.J., Kusma, S.E., Deutsch, P.J., Greenberg, H.E., Waldman, S.A.> ;J Clin Pharmacol. 2004 Mar
• Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma.
  Stone, J.A., Xu, X., Winchell, G.A., Deutsch, P.J., Pearson, P.G., Migoya, E.M., Mistry, G.C., Xi, L., Miller, A., Sandhu, P., Singh, R., deLuna, F., Dilzer, S.C., Las...> ;Antimicrob Agents Chemother. 2004 Mar
• Pharmacokinetics of total and unbound ertapenem in healthy elderly subjects.
  Musson DG, Majumdar A, Holland S, Birk K, Xi L, Mistry G, Sciberras D, Muckow J, Deutsch P, Rogers JD> ;Antimicrob. Agents Chemother.. 2004-02-01
• 139 citations
  Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone
  Jacqueline B. McCrea, Anup K. Majumdar, Michael R. Goldberg, Marian Iwamoto, Cynthia Gargano, Deborah Panebianco, Michael Hesney, Christopher Lines, Kevin J. Petty, Pa...> ;Clinical Pharmacology and Therapeutics. 2003 Jul 1
• Pharmacokinetics of intramuscularly administered ertapenem.
  Musson DG, Majumdar A, Birk K, Holland S, Wickersham P, Li SX, Mistry G, Fisher A, Waldman S, Greenberg H, Deutsch P, Rogers JD> ;Antimicrob. Agents Chemother.. 2003-05-01
• 36 citations
  Tissue Penetration by Ertapenem, a Parenteral Carbapenem Administered Once Daily, in Suction-Induced Skin Blister Fluid in Healthy Young Volunteers
  T Laethem, I De Lepeleire, Jacqueline B. McCrea, Ji Zhang, Anup K. Majumdar, D. Musson, D. Rogers, Susan X. Li, M. Guillaume, A. Parneix-Spake, Paul J. Deutsch> ;Antimicrobial Agents and Chemotherapy. 2003 Apr 1
• Steady-state pharmacokinetic interaction of modified-dose indinavir and rifabutin.
  Hamzeh FM, Benson C, Gerber J, Currier J, McCrea J, Deutsch P, Ruan P, Wu H, Lee J, Flexner C> ;Clin. Pharmacol. Ther.. 2003-03-01
• Coadministration of indinavir and nelfinavir in human immunodeficiency virus type 1-infected adults: safety, pharmacokinetics, and antiretroviral activity.
  Riddler SA, Havlir D, Squires KE, Kerr B, Lewis RH, Yeh K, Wynne LH, Zhong L, Peng Y, Deutsch P, Saah A> ;Antimicrob. Agents Chemother.. 2002-12-01
• Pharmacokinetics of ertapenem in healthy young volunteers.
  Majumdar AK, Musson DG, Birk KL, Kitchen CJ, Holland S, McCrea J, Mistry G, Hesney M, Xi L, Li SX, Haesen R, Blum RA, Lins RL, Greenberg H, Waldman S, Deutsch P, Roger...> ;Antimicrob. Agents Chemother.. 2002-11-01
• 94 citations
  Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I
  Robert B. Lobell, Dongming Liu, Carolyn A. Buser, Joseph P. Davide, Elizabeth DePuy, Kelly Hamilton, Kenneth S. Koblan, Yih Lee, Scott D. Mosser, Sherri L. Motzel, Jam...> ;Molecular Cancer Therapeutics. 2002 Jul 1
• 69 citations
  A Phase I trial of the farnesyltransferase inhibitor L-778,123 and radiotherapy for locally advanced lung and head and neck cancer
  Stephen M. Hahn, Eric J. Bernhard, William F. Regine, Mohammed Mohiuddin, Daniel G. Haller, James P. Stevenson, Debbie Smith, Barnali Pramanik, Joel E. Tepper, Thomas ...> ;Clinical Cancer Research. 2002 May 1
• 55 citations
  Characterization of a Novel Prostate-Specific Antigen–Activated Peptide-Doxorubicin Conjugate in Patients With Prostate Cancer
  Robert S. DiPaola, John J. Rinehart, John Nemunaitis, S. Ebbinghaus, Eric J. Rubin, Terry Capanna, Marie Ciardella, S. Doyle-Lindrud, Susan Goodwin, Michelle Fontaine,...> ;Journal of Clinical Oncology. 2002 Apr 1
• Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.
  Stone, J.A., Holland, S.D., Wickersham, P.J., Sterrett, A., Schwartz, M., Bonfiglio, C., Hesney, M., Winchell, G.A., Deutsch, P.J., Greenberg, H., Hunt, T.L., Waldman,...> ;Antimicrob Agents Chemother. 2002 Mar
• 69 citations
  A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies.
  Carolyn D. Britten, Eric K. Rowinsky, Steven L. Soignet, Amita Patnaik, Siu-Long Yao, Paul J. Deutsch, Yih Lee, Robert B. Lobell, Kathryn E. Mazina, Heather McCreery, ...> ;Clinical Cancer Research. 2001 Dec 1
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