PaulThomasGolumbekMD

Neurology • Saint Louis, MO

Child Neurology

Assistant Professor, Neurology, Washington University School of Medicine

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Office
4921 Parkview Pl
Ste 6c
Saint Louis, MO 63110
Phone+1 314-362-6981

Fax+1 314-362-3752
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Education & Training

University of WashingtonFellowship, Child Neurology, 1995 - 1999
Johns Hopkins University School of MedicineClass of 1995

Certifications & Licensure

MO State Medical License 2003 - 2019

Publications & Presentations

PubMed

29 citations
Twice-weekly glucocorticosteroids in infants and young boys with Duchenne muscular dystrophy.
Anne M. Connolly, Craig M. Zaidman, Paul T. Golumbek, Mary Michaeleen Cradock, Kevin M. Flanigan, Nancy L. Kuntz, Richard S. Finkel, Craig M. McDonald, Susan T. Iannac...> ;Muscle & Nerve. 2019 Jun 1
7 citations
Child Neurology: Brown-Vialetto-Van Laere syndrome: Dramatic visual recovery after delayed riboflavin therapy.
Ahmed K. Bamaga, Robi N. Maamari, Susan M. Culican, Marwan Shinawi, Paul T. Golumbek> ;Neurology. 2018 Nov 13
25 citations
De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants.
Amanda B. Rogers, Paul T. Golumbek, Elena Cellini, Viola Doccini, Renzo Guerrini, Carina Wallgren-Pettersson, Ann-Charlotte Thuresson, Christina A. Gurnett> ;American Journal of Medical Genetics. Part A. 2018 Aug 1
1200 citations
Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;The New England Journal of Medicine. 2017 Nov 1
58 citations
Association Study of Exon Variants in the NF-κB and TGFβ Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy
Luca Bello, Jaya Punetha, Heather Gordish-Dressman, Mamta Giri, Eric P. Hoffman, Andrea Barp, Sara Vianello, Elena Pegoraro, Kevin M. Flanigan, Robert B. Weiss, Pietro...> ;American Journal of Human Genetics. 2016 Nov 3
28 citations
Clinical trial readiness in non-ambulatory boys and men with duchenne muscular dystrophy: MDA-DMD network follow-up.
Anne M. Connolly, Julaine Florence, Craig M. Zaidman, Paul T. Golumbek, Jerry R. Mendell, Kevin M. Flanigan, Peter I. Karachunski, John W. Day, Craig M. McDonald, Basi...> ;Muscle & Nerve. 2016 Oct 1
53 citations
Outcome reliability in non-ambulatory boys/men with Duchenne muscular dystrophy.
Anne M. Connolly, Elizabeth C. Malkus, Jerry R. Mendell, Kevin M. Flanigan, J. Philip Miller, Jeanine Schierbecker, Catherine Siener, Paul T. Golumbek, Craig M. Zaidma...> ;Muscle & Nerve. 2015 Apr 1
33 citations
One Year Outcome of Boys With Duchenne Muscular Dystrophy Using the Bayley-III Scales of Infant and Toddler Development
Anne M. Connolly, Julaine Florence, Mary Michaeleen Cradock, Michelle Eagle, Kevin M. Flanigan, Craig M. McDonald, Peter I. Karachunski, Basil T. Darras, Kate Bushby, ...> ;Pediatric Neurology. 2014 Jun 1
56 citations
Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function
Kristin P. Bibee, Ya-Jian Cheng, James Kain Ching, Jon N. Marsh, Allison Jinquan Li, Richard M. Keeling, Anne M. Connolly, Paul T. Golumbek, Jacob W. Myerson, Grace Hu...> ;FASEB Journal. 2014 May 1
70 citations
Motor and cognitive assessment of infants and young boys with Duchenne Muscular Dystrophy: results from the Muscular Dystrophy Association DMD Clinical Research Network.
Anne M. Connolly, Julaine Florence, Mary Michaeleen Cradock, Elizabeth C. Malkus, Jeanine Schierbecker, Catherine Siener, Charlie Wulf, Pallavi Anand, Paul T. Golumbek...> ;Neuromuscular Disorders. 2013 Jul 1
3 citations
Pharmacologic Agents for Pediatric Neuroimmune Disorders
Paul T. Golumbek> ;Seminars in Pediatric Neurology. 2010 Dec 1
136 citations
Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis
Jason R. Lees, Paul T. Golumbek, Julia Sim, Denise A. Dorsey, John H. Russell> ;The Journal of Experimental Medicine. 2008 Oct 27
6 citations
RAG2 gene knockout in mice causes fatigue.
Paul T. Golumbek, Richard M. Keeling, Anne M. Connolly> ;Muscle & Nerve. 2007 Oct 1
23 citations
Strength and corticosteroid responsiveness of mdx mice is unchanged by RAG2 gene knockout
Paul T. Golumbek, Richard M. Keeling, Anne M. Connolly> ;Neuromuscular Disorders. 2007 May 1
51 citations
Weekly oral prednisolone improves survival and strength in male mdx mice.
Richard M. Keeling, Paul T. Golumbek, Elizabeth M. Streif, Anne M. Connolly> ;Muscle & Nerve. 2007 Jan 1
181 citations
Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy.
Anne M. Connolly, Michael G. Chez, Elizabeth M. Streif, Richard M. Keeling, Paul T. Golumbek, Jennifer M. Kwon, James J. Riviello, Ricki Robinson, Rosalind J. Neuman, ...> ;Biological Psychiatry. 2006 Feb 15
25 citations
Neurologic manifestations of celiac disease: proven, or just a gut feeling?
Anne H. Cross, Paul T. Golumbek> ;Neurology. 2003 May 27
950 citations
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
Alex Yee-Chen Huang, Paul Golumbek, Mojgan Ahmadzadeh, Elizabeth M. Jaffee, Drew M. Pardoll, Hyam I. Levitsky> ;Science. 1994 May 13
26 citations
Bone marrow-derived cells present MHC class I-restricted tumour antigens in priming of antitumour immune responses.
Alex Yee-Chen Huang, Paul Golumbek, Mojgan Ahmadzadeh, Elizabeth M. Jaffee, D. Pardoll, H. Levitsky> ;Ciba Foundation Symposium. 1994 Jan 1
134 citations
Controlled Release, Biodegradable Cytokine Depots: A New Approach in Cancer Vaccine Design
Paul Golumbek, Rosa Azhari, Elizabeth M. Jaffee, Hyam I. Levitsky, Audrey J. Lazenby, Kam W. Leong, Drew M. Pardoll> ;Cancer Research. 1993 Dec 15
2223 citations
Vaccination with Irradiated Tumor Cells Engineered to Secrete Murine Granulocyte-Macrophage Colony-Stimulating Factor Stimulates Potent, Specific, and Long-Lasting Ant...
Glenn Dranoff, Elizabeth M. Jaffee, Audrey J. Lazenby, Paul Golumbek, Hyam I. Levitsky, Katja Brose, Valerie Jackson, Hirofumi Hamada, Drew M. Pardoll, Richard C. Mull...> ;Proceedings of the National Academy of Sciences of the United States of America. 1993 Apr 15
16 citations
The antitumor immune response as a problem of self-nonself discrimination: implications for immunotherapy.
Paul Golumbek, Hy Levitsky, Liz Jaffee, Drew M. Pardoll> ;Immunologic Research. 1993 Jun 1
53 citations
Herpes simplex-1 virus thymidine kinase gene is unable to completely eliminate live, nonimmunogenic tumor cell vaccines.
Paul Golumbek, Fayez M. Hamzeh, Elizabeth M. Jaffee, Hyam I. Levitsky, Paul S. Lietman, Drew M. Pardoll> ;Journal of Immunotherapy. 1992 Nov 1
7 citations
Molecular engineering of the antitumor immune response.
Drew M. Pardoll, Paul Golumbek, H. Levitsky, Liz M. Jaffee> ;Bone Marrow Transplantation. 1992 Jan 1
586 citations
Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4
Paul Golumbek, Audrey J. Lazenby, Hyam I. Levitsky, Liz M. Jaffee, Hajime Karasuyama, Mitzi Baker, Drew M. Pardoll> ;Science. 1991 Nov 1
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Press Mentions

This 6-Year-Old Suddenly Had Trouble Reading. Why Was She Going Blind?August 16th, 2017
YOUR HEALTH: How the B2 Vitamin Is Saving a GirlMay 12th, 2017