PaulAlanKlekotkaMD

PubMed

• 1 citations
  A randomized, placebo-controlled clinical trial of bamlanivimab and etesevimab together in high-risk ambulatory patients with COVID-19 and validation of the prognostic...
  Michael Dougan, Masoud Azizad, Bharat Mocherla, Robert L. Gottlieb, Peter Chen, Corey Hebert, Russell Perry, Joseph Boscia, Barry Heller, Jason Morris, Chad Crystal, A...> ;Clinical Infectious Diseases. 2021 Oct 28
• 7 citations
  Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy
  Manish Chandra Choudhary, Kara W Chew, Rinki Deo, James P. Flynn, James Regan, Charles R Crain, Carlee Moser, Michael Hughes, Justin Ritz, Ruy M. Ribeiro, Ruian Ke, Jo...> ;medRxiv. 2021 Sep 15
• 5 citations
  First-in-Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients With COVID-19.
  Peter Chen, Gourab Datta, Ying Grace Li, Jenny Y. Chien, Karen L. Price, Emmanuel Chigutsa, Patricia Brown-Augsburger, Josh Poorbaugh, Jeffrey Fill, Robert J. Benschop...> ;Clinical Pharmacology & Therapeutics. 2021 Oct 16
• 142 citations
  Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19.
  Michael Dougan, Ajay Nirula, Masoud Azizad, Bharat Mocherla, Robert L. Gottlieb, Peter Chen, Corey Hebert, Russell Perry, Joseph Boscia, Barry Heller, Jason Morris, Ch...> ;The New England Journal of Medicine. 2021 Jul 14
• 69 citations
  Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial
  Myron S. Cohen, Ajay Nirula, Mark J. Mulligan, Richard M. Novak, Mary A. Marovich, Catherine Yen, Alexander Stemer, Stockton Mayer, David A. Wohl, Blair Brengle, Brian...> ;JAMA. 2021 Jul 6
• 391 citations
  Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.
  Robert L. Gottlieb, Ajay Nirula, Peter Chen, Joseph Boscia, Barry Heller, Jason Morris, Gregory D. Huhn, Jose Cardona, Bharat Mocherla, Valentina Stosor, Imad Shawa, P...> ;JAMA. 2021 Feb 16
• 605 citations
  SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19.
  Peter Chen, Ajay Nirula, Barry Heller, Robert L. Gottlieb, Joseph Boscia, Jason Morris, Gregory D. Huhn, Jose Cardona, Bharat Mocherla, Valentina Stosor, Imad Shawa, A...> ;The New England Journal of Medicine. 2021 Jan 21
• 176 citations
  A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.
  J D Lundgren, Birgit Grund, Christina E. Barkauskas, Thomas L. Holland, Robert L. Gottlieb, Uriel Sandkovsky, Samuel M. Brown, Kirk U. Knowlton, Wesley H. Self, D. Cla...> ;The New England Journal of Medicine. 2021 Mar 11
• 33 citations
  The Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD): The development and reliability testing of a novel clinical outcome measurement instrumen...
  Eric L. Simpson, Robert Bissonnette, Lawrence F. Eichenfield, Emma Guttman-Yassky, Brett A. King, Jonathan I. Silverberg, Lisa A. Beck, Thomas Bieber, Kristian Reich, ...> ;Journal of The American Academy of Dermatology. 2020 Sep 1
• 13 citations
  Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis
  Lewis Tomalin, Chris B. Russell, Sandra Garcet, David Adrian Ewald, Paul Klekotka, Ajay Nirula, Hanne Norsgaard, Mayte Suárez-Fariñas, James G. Krueger> ;The Journal of Allergy and Clinical Immunology. 2020 Mar 1
• 53 citations
  Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Ulcerative Colitis.
  William J. Sandborn, Marc Ferrante, Bal R. Bhandari, Elina Berliba, Brian G. Feagan, Toshifumi Hibi, Jay Tuttle, Paul Klekotka, Stuart Friedrich, Michael Durante, Mary...> ;Gastroenterology. 2020 Feb 1
• 43 citations
  Efficacy and safety of mirikizumab (LY3074828) in the treatment of moderate-to-severe plaque psoriasis: results from a randomized phase II study.
  Kristian Reich, Phoebe Rich, Catherine Maari, Robert Bissonnette, C. Leonardi, Alan Menter, Atsuyuki Igarashi, Paul Klekotka, Dipak R. Patel, J Li, Jay Tuttle, MaryAnn...> ;British Journal of Dermatology. 2019 Jul 1
• 7 citations
  Measurement Properties of the Psoriasis Symptom Inventory Electronic Daily Diary in Patients with Moderate to Severe Plaque Psoriasis.
  Hema N. Viswanathan, Alex Mutebi, Cassandra E Milmont, Kenneth B. Gordon, Hilary Wilson, Hao Zhang, Paul Klekotka, Dennis A. Revicki, Matthias Augustin, Gregory Kricor...> ;Value in Health. 2017 Sep 1
• 138 citations
  Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, in Patients With Moderate to Severe Crohn’s Disease: A Phase 2a Study
  Bruce E. Sands, Jingjing Chen, Brian G. Feagan, Mark Penney, William Rees, Silvio Danese, Peter D.R. Higgins, Paul Newbold, Raffaella Faggioni, Kaushik Patra, Jing Li,...> ;Gastroenterology. 2017 Jul 1
• 61 citations
  Clinical meaningfulness of complete skin clearance in psoriasis
  Bruce Strober, Kim A. Papp, Mark Lebwohl, Kristian Reich, Carle Paul, Andrew Blauvelt, Kenneth B. Gordon, Cassandra E Milmont, Hema N. Viswanathan, Joanne Li, Lionel P...> ;Journal of The American Academy of Dermatology. 2016 Jul 1
• 35 citations
  Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases.
  Ajay Nirula, Jon Nilsen, Paul Klekotka, Greg Kricorian, Ngozi Erondu, Jennifer E. Towne, Chris B. Russell, David Martin, Alison L. Budelsky> ;Rheumatology. 2016 Dec 1
• 190 citations
  A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's Disease.
  Stephan R. Targan, Brian G. Feagan, Severine Vermeire, Remo Panaccione, Gil Y. Melmed, Carol J. Landers, Dalin Li, Chris B. Russell, Richard Newmark, Nan Zhang, Yun Ch...> ;The American Journal of Gastroenterology. 2016 Aug 2
• 5 citations
  Development of the chronic obstructive pulmonary disease morning symptom diary (COPD-MSD)
  Brooke Currie, Nancy Kline Leidy, Paul W. Jones, David M. Mannino, Fernando J. Martinez, Paul Klekotka, Sean O'Quinn, Niklas Karlsson, Ingela Wiklund> ;Health and Quality of Life Outcomes. 2016 Jul 16
• 275 citations
  A prospective phase III, randomized, double-blind, placebo-controlled study of brodalumab in patients with moderate-to-severe plaque psoriasis†
  Kim A. Papp, Kristian Reich, Carle Paul, Andrew Blauvelt, W. Baran, Chantal Bolduc, Darryl Toth, Richard G. Langley, J. Cather, Alice B. Gottlieb, Diamant Thaçi, James...> ;British Journal of Dermatology. 2016 Jun 23
• 19 citations
  Differences in psoriasis signs and symptom severity between patients with clear and almost clear skin in clinical practice.
  Steven R. Feldman, Donald M. Bushnell, Paul Klekotka, M. Scanlon, Mona L. Martin, Sally W. Wade, Wenjing Yang, Lionel Pinto, Leon H Kircik, Hema N. Viswanathan> ;Journal of Dermatological Treatment. 2016 Jan 1
• 38 citations
  Biomarker Profiles in Asthma With High vs Low Airway Reversibility and Poor Disease Control.
  William W. Busse, Stephen T. Holgate, Sally W. Wenzel, Paul Klekotka, Yun Chon, J. Feng, Edward P. Ingenito, Ajay Nirula> ;Chest. 2015 Dec 1
• Real World Skin Clearance Rates for Biologic Treatments In Patients With Moderate to Severe Plaque Psoriasis: Interim Results From A Large Prospective, Observational S...
  Carle Paul, Anthony Bewley, Giampiero Girolomoni, Kristian Reich, Lluís Puig, Jean-Philippe Lacour, Matthias Augustin, Luigi Naldi, Alan Menter, S Wade, Hema N. Viswan...> ;Value in Health. 2015 Nov 1
• 473 citations
  Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis
  Mark Lebwohl, Bruce Strober, Alan Menter, Kenneth B. Gordon, Jolanta Weglowska, Lluís Puig, Kim A. Papp, Lynda Spelman, Darryl Toth, Francisco A. Kerdel, April W. Arms...> ;The New England Journal of Medicine. 2015 Sep 30
• 50 citations
  Total skin clearance results in improvements in health-related quality of life and reduced symptom severity among patients with moderate to severe psoriasis
  Hema N. Viswanathan, Dina Chau, Cassandra E Milmont, Wenjjing Yang, Ngozi Erondu, Dennis A. Revicki, Paul Klekotka> ;Journal of Dermatological Treatment. 2015 Jul 22
• 35 citations
  Efficacy and safety of brodalumab in subpopulations of patients with difficult-to-treat moderate-to-severe plaque psoriasis.
  Kim A. Papp, Alan Menter, Bruce Strober, Greg Kricorian, Elizabeth H.Z. Thompson, Cassandra E Milmont, Ajay Nirula, Paul Klekotka> ;Journal of The American Academy of Dermatology. 2015 Mar 1
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