Paul Lindholm, MD, Pathology, Chicago, IL, Northwestern Memorial Hospital

PaulLindholmMD

Pathology • Chicago, IL

Blood Banking & Transfusion Medicine, Hematopathology, Transplantation Immunology, Clinical Pathology

Professor of Pathology, Northwestern University Medical School

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Summary

  • As a seasoned medical doctor and clinical educator, I have dedicated my professional career to not only patient-centered outcomes, but to making significant contributions to research and teaching in the areas of hemostasis and coagulation.

    Currently, as the Medical Director Northwestern Medicine Hemostasis and Coagulation Laboratory where I oversee research and patient outcomes while also interpreting patient coagulation and platelet function assays for our physicians. Additionally, I co-direct the NMH Blood Bank and Molecular Diagnostic Laboratories. In both of these situations, I strive to teach and provide safest transfusion practices and optimal service and quality in laboratory hemostasis and coagulation testing.

    My special clinical and academic interest concerns thrombosis and thrombophilia or the pathologic development of blood clots. I am interested in the etiology and pathogenesis of thrombosis and in the methods for providing therapeutic monitoring for anticoagulation therapies, with a special interest in pathological thrombosis that develops in many cancer patients, in an effort to understand the major causes of patient morbidity and mortality and then design successful therapies to prevent and treat these adverse outcomes for patients.

    While my research often takes center stage, my responsibilities also include extensive teaching and administrative responsibilities. I excel in situations that require structured teamwork with individuals with diverse intellectual and personal perspectives. I also take great pride in my work, and strike to adhere to the standards, protocols, and regulations surrounding research projects of this magnitude.

Education & Training

  • National Cancer InstituteFellowship, Molecular Virology, 1988 - 1994
  • University of Minnesota at Fairview
    University of Minnesota at FairviewResidency, Anatomic and Clinical Pathology, 1983 - 1988
  • University of Minnesota Medical School
    University of Minnesota Medical SchoolClass of 1983
  • University of Minnesota MinneapolisB.A, Biometry, Summa cum laude, 1979
  • University of Minnesota
    University of MinnesotaB.A., Biometry, Summa cum laude, 1979

Certifications & Licensure

  • IL State Medical License
    IL State Medical License 2002 - 2023
  • WI State Medical License
    WI State Medical License 1994 - 2003
  • MN State Medical License
    MN State Medical License 1984 - 1994
  • American Board of Pathology Anatomic Pathology & Clinical Pathology
  • American Board of Pathology Blood Banking/Transfusion Medicine

Awards, Honors, & Recognition

  • Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011
  • PEDF regulation of adipogenesis and leptin in prostate cancer Co-Investigator, Main Project, Northwestern University Robert H. Lurie Cancer Center Prostate S.P.O.R.E, 2009, 2014
  • RhoA and Transcription Factor Regulation of Prostate Cancer Cell Invasion Career Development Project, Northwestern University Robert H. Lurie Cancer Center Prostate S.P.O.R.E, 2003, 2006
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Publications & Presentations

PubMed

Journal Articles

  • Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: towards large-scale platelet production.  
    S Panuganti, AC Schlinker, PF Lindholm, ET Papoutsakis and WM Miller, Tissue Engineering, 1/1/2013
  • Early Platelet Transfusion Improves Platelet Activity and May Reduce Final Hematoma Size.  
    AM Naidech, SM Liebling, NF Rosenberg, PF Lindholm, RA Bernstein, H Batjer, MJ Alberts and HC Kwaan, Neurocritical Care, 1/1/2012
  •  
    Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ, Kozlowski J, Smith N, Kundu SD, Yang G, Raji AA, Javonovic B, Pins M, Lindholm P, Guo Y, Catalona WJ, Lee C, Clin Cancer Res, 5/15/2009
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Books/Book Chapters

  • Infect Disorders Drug Targets. 
    Chapter: Approaches to Minimize Infection Risk in Blood Banking and Transfusion Practice. 
    Page 45 - 56PF Lindholm, K Annen, G Ramsey2011
  • Metal Ions in Biology and Medicine 
    Chapter: The effect of iron on prostate and breast cancer cell invasion. 
    Page 617 - 620Kajdacsy-Balla AA, S Kaul, C Chitambar, PF LindholmEditors: L Khassanova, P Collery, I Maymard, Z Khassanova, J-C Etienne.John Libbey Eurotext, Paris2002
  • Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 
    Chapter: Determination of Cyclooxygenase and Arachidonic Acid Metabolites in Invasive Human Prostate Cancer Cells. 
    Nithipatikom K, Borscheid CL, Kajdacsy-Balla A, Kaul S, Lindholm PF, Pytynia KB, Campbell WBEditors: Honn KV, Marnett LJ, Nigam S, Dennis E, Serhan C.Kluwer Academic/Plenum Publishers, New York, NY2002
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Abstracts/Posters

  • Production of high-ploidy megakaryocytic cells and functional platelets in culture using a 3-phase process.
    AC Schlinker, S Panuganti, PF Lindholm, ET Papoutsakis, WM Miller, Gordon Research Conference Cell Biology of Megakaryocytes & Platelets in Galveston, TX, 3/9/2013
  • Production of high-ploidy megakaryocytic cells and functional platelets in culture using a 3-phase process.
    AC Schlinker, S Panuganti, PF Lindholm, ET Papoutsakis, WM Miller, ECI cell-based therapies conference Scale-Up and Manufacturing of Cell Based Therapies II, San Diego, 1/21/2013
  • G Ramsey, Mroz, P, Thompson AA, Williams LM, Lindholm PF, Crowley, Horn JT, Keller, MA, American Association of Blood Banks 2012 Annual Meeting in Boston, MA, 10/6/2012
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Hospital Affiliations

Dr. Paul Lindholm, Dr. Paul Lindholm, MD, Dr. P Lindholm