PaulAtkinsonMannJr.MD

PubMed

• 39 citations
  Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins
  Anna Konovalova, Marcin Grabowicz, Carl J. Balibar, Juliana C. Malinverni, Ronald E. Painter, Daniel Riley, Paul Mann, Hao Wang, Charles G. Garlisi, Brad Sherborne, Na...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 10
• 80 citations
  TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci
  Sang Ho Lee, Hao Wang, Marc A. Labroli, Sandra Koseoglu, Paul Zuck, Todd Mayhood, Charles Gill, Paul Mann, Xinwei Sher, Sookhee Ha, Shu-Wei Yang, Mihir Mandal, Christi...> ;Science Translational Medicine. 2016 Mar 9
• 246 citations
  Selective small-molecule inhibition of an RNA structural element
  John A. Howe, Hao Wang, Thierry O. Fischmann, Carl J. Balibar, Li Xiao, Andrew Galgoci, Juliana C. Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Mu...> ;Nature. 2015 Oct 29
• 56 citations
  Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis
  Paul A. Mann, Catherine A. McLellan, Sandra Koseoglu, Qian Si, Elena Kuzmin, Amy M. Flattery, Guy H. Harris, Xinwei Sher, Nicholas J. Murgolo, Hao Wang, Kristine Devit...> ;ACS Infectious Diseases. 2015 Jan 9
• 41 citations
  Murgocil is a highly bioactive staphylococcal-specific inhibitor of the peptidoglycan glycosyltransferase enzyme MurG.
  Paul Mann, Anna Müller, Li Xiao, Pedro M. Pereira, Christine Yang, Sang Ho Lee, Hao Wang, Joanna Trzeciak, Jonathan Schneeweis, Margarida Moreira dos Santos, Nicholas ...> ;ACS Chemical Biology. 2013 Sep 5
• Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA ?-Lactam Combination Agents.
  Wang, H.,Gill, C. J.,Lee, S. H.,Mann, P.,Zuck, P.,Meredith, T. C.,Murgolo, N.,She, X.,Kales, S.,Liang, L.,Liu, J.,Wu, J.,Santa Maria, J.,Su, J.,Pan, J.,Hailey, J.,McGu...> ;Chem. Biol.. 2013 Feb 21
• 45 citations
  Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors
  Scott S. Walker, Yiming Xu, Ilias Triantafyllou, Michelle F. Waldman, Cara A. Mendrick, Nathaniel Brown, Paul Mann, Andrew S. Chau, Reena Patel, Nicholas Bauman, Chris...> ;Antimicrobial Agents and Chemotherapy. 2011 Nov 1
• 20 citations
  Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1).
  Paul M. McNicholas, Paul A. Mann, Lisa Wojcik, Ping Qiu, Erin Lee, Michael McCarthy, Junwu Shen, Todd A. Black, Julie M. Strizki> ;Journal of Acquired Immune Deficiency Syndromes. 2011 Mar 1
• 64 citations
  Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species
  Paul A. Mann, Paul M. McNicholas, Andrew Chau, Reena Patel, Cara Mendrick, Andrew J. Ullmann, Oliver A. Cornely, Hernando Patino, Todd A. Black> ;Antimicrobial Agents and Chemotherapy. 2009 Dec 1
• 20 citations
  Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae
  Andrew S. Chau, Guodong Chen, Paul M. McNicholas, Paul A. Mann> ;Antimicrobial Agents and Chemotherapy. 2006 Nov 1
• 332 citations
  In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts.
  F J Sabatelli, Reena Patel, Paul A. Mann, Cara Mendrick, Christine Norris, Roberta S. Hare, David Loebenberg, Todd A. Black, Paul M. McNicholas> ;Antimicrobial Agents and Chemotherapy. 2006 Jun 1
• 63 citations
  Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds
  H. Munayyer, Paul A. Mann, Andrew S. Chau, Taisa Yarosh-Tomaine, Jonathan R. Greene, Roberta S. Hare, Larry Heimark, Robert Palermo, David Loebenberg, Paul M. McNicholas> ;Antimicrobial Agents and Chemotherapy. 2004 Oct 1
• 183 citations
  Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole
  Adriana Mendes do Nascimento, Gustavo H. Goldman, Steven Park, Salvatore A. E. Marras, Guillaume Delmas, Uma Oza, Karen Lolans, Michael N. Dudley, Paul A. Mann, David ...> ;Antimicrobial Agents and Chemotherapy. 2003 May 1
• 145 citations
  Mutations in Aspergillus fumigatus Resulting in Reduced Susceptibility to Posaconazole Appear To Be Restricted to a Single Amino Acid in the Cytochrome P450 14α-Demeth...
  Paul A. Mann, Raulo Parmegiani, Shui-Qing Wei, Cara Mendrick, Xin Li, David Loebenberg, Beth DiDomenico, Roberta S. Hare, Scott S. Walker, Paul M. McNicholas> ;Antimicrobial Agents and Chemotherapy. 2003 Feb 1
• 20 citations
  Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin
  Paul M. McNicholas, Paul A. Mann, David J. Najarian, Lynn Miesel, Roberta S. Hare, Todd A. Black> ;Antimicrobial Agents and Chemotherapy. 2001 Jan 1
• 51 citations
  Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria
  Paul M. McNicholas, David J. Najarian, Paul A. Mann, David Hesk, Roberta S. Hare, Karen J. Shaw, Todd A. Black> ;Antimicrobial Agents and Chemotherapy. 2000 May 1
• 14 citations
  Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase.
  P N Rather, Paul A. Mann, R Mierzwa, Roberta S. Hare, George H. Miller, K J Shaw> ;Antimicrobial Agents and Chemotherapy. 1993 Oct 1
• 74 citations
  Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens.
  K J Shaw, P N Rather, F J Sabatelli, Paul A. Mann, H. Munayyer, R Mierzwa, G. L. Petrikkos, Roberta S. Hare, George H. Miller, P. Bennett, P. Downey> ;Antimicrobial Agents and Chemotherapy. 1992 Jul 1
• 59 citations
  Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates.
  K J Shaw, Roberta S. Hare, F J Sabatelli, M Rizzo, C A Cramer, L. Naples, S Kocsi, H. Munayyer, Paul A. Mann, George H. Miller> ;Antimicrobial Agents and Chemotherapy. 1991 Nov 1
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